• Subjects with suspected liver disease (SLD), defined on the basis of elevated serum alanine aminotransferase (ALT) and gamma-glutamyl-transferase (GGT) activity, hepatitis B surface antigen (HBsAg), or hepatitis C virus (HCV)-RNA positivity, were matched with randomly selected subjects of the same age and sex without SLD. (nih.gov)
  • Indirect alcohol biomarkers include aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma glutamyltransferase (GGT), mean corpuscular volume (MCV), and carbohydrate-deficient transferrin (CDT). (medscape.com)
  • There is insufficientc Includes the following terms: alanine aminotransferase increased, gamma-glutamyl transferase increased, aspartate information to determine the reversibility of the decrease in FEV 1or FVC after drug discontinuation. (usmedicine.com)
  • The Clinical Laboratory Improvement Amendments criteria were used in evaluating the laboratories, and their success rates were compared with the World Health Organization Regional Office for Africa's target of 80%.Results: The overall rate of acceptable results at the laboratories was over 80% for glucose, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyltransferase, alkaline phosphatase and triglycerides tests. (bvsalud.org)
  • Gamma-glutamyl transferase (GGT) is a cellular production of oxidants. (medscimonit.com)
  • Gamma glutamyl transferase (GGT) was significantly higher in repeat donors (70.5 ± 13.5 μl) than the first time donors (62.5 ± 13.3 μl) (P (scirp.org)
  • T. Adias, A. Igwilo and Z. Jeremiah, "Repeat Whole Blood Donation Correlates Significantly with Reductions in BMI and Lipid Profiles and Increased Gamma Glutamic Transferase (GGT) Activity among Nigerian Blood Donors," Open Journal of Blood Diseases , Vol. 2 No. 4, 2012, pp. 90-94. (scirp.org)
  • The most common Grade 3 or 4 laboratory abnormalities (≥ 2%) were decreased lymphocytes, decreased albumin, decreased phosphate, decreased potassium, increased alkaline phosphatase, increased glucose, increased gamma-glutamyl transferase, and decreased sodium. (drugs.com)
  • b'B:8.5"T:8.25"S:7.25"body, women of childbearing potential should use effective contraception to avoid pregnancy during treatment and forTable 2:Adverse Reactions with an Incidence of at Least 2% in ZEPOSIA (ozanimod)-Treated Patients 3 months after stopping ZEPOSIA (ozanimod) [see Use in Specific Populations]. (usmedicine.com)
  • The aim of this study was to investigate the common causes and routine diagnostic and therapeutic methods of acute pancreatitis in children in a pediatric gastrointestinal referral center and its accordance with existing guidelines. (biomedcentral.com)
  • Methods Using an ambispective cohort study, 565 Kazakhs from Xinjiang, China were selected as the study subjects. (researchsquare.com)
  • Analysis of the study results of the effect of neurotoxic OPCs, triorthocresyl phosphate (TOCP), Afos on the immune system was performed using the most sensitive model - chicken breed Leghorn in isotoxic doses (500 mg/kg and 200 mg/kg, respectively) using common immunotoxicology methods. (kiev.ua)
  • However, participation in such PT programmes assists improves test performance and result accuracy.Objective: This study assessed how well 11 government hospital laboratories performed 18 basic clinical chemistry tests and identified areas needing improvement.Methods: A cross-sectional study was carried out by the Division of Laboratories of the Ministry of Health of Togo from 01 July 2016 to 31 December 2016. (bvsalud.org)
  • Background Some studies have shown that a high level of bilirubin is a protective factor against the metabolic syndrome (MS), while a high level of transaminase is a risk factor for the MS. However, the results are inconsistent, and there are few cohort studies. (researchsquare.com)
  • A previous study by our research group found the prevalence of MS in Kazakhs to be higher than other ethnic groups in Xinjiang and the national average[ 13 ].Therefore, this study takes Xinjiang Kazakh residents as the research group and explores the relationship between both serum bilirubin and transaminase with MS and its components. (researchsquare.com)
  • The prevalence of and the risk factors for fatty liver have not undergone a formal evaluation in a representative sample of the general population. (nih.gov)
  • Furthermore, it has a greater sensitivity in populations with a lower prevalence of alcoholism. (medscape.com)
  • The main objective of this study was to investigate the prevalence of T. gondii among adults in the United States and its association with cardiovascular health using data from the National Health and Nutrition Examination Survey (NHANES 2009-2010). (mdpi.com)
  • Ong KL, 2022, 'Relationship of fibroblast growth factor 21 with the prevalence and progression of vascular and valvular calcification: Multi-ethnic study of atherosclerosis. (edu.au)
  • 1 , - , 4 This high variability may reflect the different populations considered: in fact, low severity of disease, low comorbidity burden, female sex, and younger age all seem to be associated with a higher prevalence of these symptoms. (neurology.org)
  • This study aimed to determine the prevalence of BFS among Nigerian university students and examine its associated factors. (bvsalud.org)
  • Conclusion: The high prevalence highlights the need for attention to mental health issues among this population. (bvsalud.org)
  • Objective: To determine the effect of video information in addition to the pre-anesthetic review on the mean preoperative State anxiety inventory (STAI-S) score in adult patients presenting for elective caesarean section under spinal anesthesia at Aga Khan University Hospital, Nairobi (AKUHN), and to determine the prevalence of preoperative anxiety in the obstetric population presenting for elective caesarean section at AKUHN. (bvsalud.org)
  • Gastric emptying and the global symptom response to a standardised nutrient challenge are abnormal in population based (non-health care seeking) subjects with dyspepsia. (bmj.com)
  • In conclusion, NAFLD is highly prevalent in the general population, is not associated with SLD, but is associated with many features of the metabolic syndrome. (nih.gov)
  • We aimed to elucidate the relationship of serum GGT levels and coronary artery disease (CAD) in a Chinese population. (medscimonit.com)
  • Our study aimed to determine the association between non-alcoholic fatty liver and increased epicardial adipose tissue mass with coronary artery disease severity. (springeropen.com)
  • This study was conducted on sixty patients who presented with symptoms of coronary artery disease and attended elective coronary angiography to rule out coronary artery disease. (springeropen.com)
  • One of the main concerns of the cardiology studies is how to prevent coronary artery disease development and how to estimate the risk of the disease before it becomes clinically symptomatic [ 1 ]. (springeropen.com)
  • In this retrospective, cross-sectional study, a total of 60 children with a diagnosis of acute pancreatitis, were studied. (biomedcentral.com)
  • More research should be done to study the association between COVID-19 and acute pancreatitis. (biomedcentral.com)
  • As only few original studies have investigated acute pancreatitis in children in Iran, in the present study, the clinical manifestations and etiological factors of this disease, as well as diagnostic and therapeutic measures, were investigated in children. (biomedcentral.com)
  • In this retrospective, cross-sectional study, a total of 60 children with a diagnosis of acute pancreatitis, admitted to Children's Medical Center Hospital in Tehran, Iran, from 2013 to 2020, were studied. (biomedcentral.com)
  • Based on the evaluation of medical records, patients under the age of 18 years, who met the diagnostic criteria for acute pancreatitis according to the INSPPIRE criteria, were included in the study. (biomedcentral.com)
  • The article analyses and concludes current literary data on the justified use of biomarkers of exposure and effect of OPCs that are widespread in the environmental objects and are one of the reasons of acute and chronic poisoning in the population. (kiev.ua)
  • During the last two decades, organophosphorus pesticides are directly the main reason of acute and chronic poisoning with pesticides among the agricultural workers, among population following household use as insecticides, as well as following accidental or deliberate use that requires emergency medical care, precise diagnostics, effective treatment, and prediction of consequences of intoxication [4, 6, 8-11]. (kiev.ua)
  • This new viral agent, known today as COVID-19, is the cause of atypical viral pneumonia and acute respiratory distress syndrome that affects all the world population(4). (bvsalud.org)
  • describir las alteraciones de los parámetros de laboratorio de pacientes con COVID 19 ingresados al Hospital Fundación Tesãi de Ciudad del Este-Paraguay en el período de julio de 2020 a octubre de 2021. (bvsalud.org)
  • The aim of the study and the questions in a substantial contribution to the burden of the questionnaire form were fully explained disease and premature mortality [ 2 ]. (who.int)
  • We recorded patients' em- ing at levels causing detectable biochemical ployment and economic status (monthly abnormalities is associated with mortality or daily income) and consumption of other that is twice that of the normal population psychoactive drugs. (who.int)
  • Non-invasive fatty liver markers predict liver disease mortality in the United States population. (cdc.gov)
  • ABSTRACT This study was conducted to investigate the preliminary environmental and mammalian toxicol- ogy of neem oil, temephos and chlorpyriphos-methyl/fenitrothion. (who.int)
  • Studies on hepatic vasculature can be informative about parenchymal injury and disease severity through the study of changes affecting vascular compliance. (springeropen.com)
  • This study aimed to study portal vein and hepatic artery hemodynamic variation in non-alcoholic fatty liver and to correlate it with disease severity. (springeropen.com)
  • Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o. (medscimonit.com)
  • A retrospective study using the medical charts of 103 patients admitted to the hospital due to a diagnosis of COVID-19 was carried out. (bvsalud.org)
  • In addition, the corresponding clinical characteristics of the two diagnostic criteria populations were compared. (xiahepublishing.com)
  • 1996). "Prediction of risk of liver disease by alcohol intake, sex, and age: a prospective population study" . (wikidoc.org)
  • Due to information bias, it may not be possible to accurately estimate the actual alcohol intake of the study subjects. (xiahepublishing.com)
  • This study aims to identify metabolic, clinical, and microbiota differences between small and larger dogs. (hindawi.com)
  • We conducted a diet- and environment-controlled study in canines to understand metabolic, clinical, and microbiota differences between small and larger dogs. (hindawi.com)
  • This provides theoretical support for early diagnosis and prevention of metabolic syndrome in the Xinjiang Kazakh population and may provide evidence for people living in Kazakhstan and Uzbekistan. (researchsquare.com)
  • Epidemiologic studies have shown associations between tetrachloroethylene exposure and several types of cancer. (cdc.gov)
  • The study showed a positive correlation between serum GGT and CAD in a Chinese population. (medscimonit.com)
  • Therefore, we aimed to compare the difference in epidemiological and clinical characteristics between MAFLD and non-alcoholic fatty liver disease (NAFLD) among Asian populations. (xiahepublishing.com)
  • First, due to differences in the basic characteristics, living habits and genetic susceptibility of the population, the clinical manifestations, pathological characteristics and clinical outcomes of NAFLD are obviously heterogeneous. (xiahepublishing.com)
  • All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment. (wjgnet.com)
  • For example, the results of a recent study of the interaction between peculiarities of nutrition of Canadian population (5,604 subjects aged 6 to 79 years) and concentrations of OPCs metabolites (dialkyl phosphates) in urine suggest that more than 90 % of participants had at least one type of dialkyl phosphates in urine samples. (kiev.ua)
  • Results:The study included a total of 625 participants, in their young adulthood. (bvsalud.org)
  • Key Words: Appetite, ileal break, orocecal transit time, overweight, weight maintenance ''Fabuless'' is a stable fat emulsion consisting of palm oil and oat oil that can reduce food intake and Overweight and obesity have become a global epi- enhance satiety [4 7], although not all such studies demic, associated with significant increases in mor- have yielded significant effects [8]. (marysfamilymedicine.org)
  • 100 kilocalories per day (e.g. 4% of daily energy The mechanism by which this stable fat emulsion intake), weight gain in most of the US population exerts these short- and long-term effects has so could be prevented [3]. (marysfamilymedicine.org)
  • The results of the above mentioned studies are inconsistent. (researchsquare.com)
  • In this respect, although many studies have shown a relation between diabetes and elevated liver enzymes, the results remain inconsistent [ 12 ]. (biomedcentral.com)
  • The results emphasize the importance of considering the course of study and academic performance when studying BFS. (bvsalud.org)
  • The results of surveys, analyses, and studies are made known through a number of data release mechanisms including publications, mainframe computer data files, CD-ROMs (Search and Retrieval Software, Statistical Export and Tabulation System (SETS)), and the Internet (http://www.cdc.gov/nchswww/nchshome.htm). (cdc.gov)
  • We used data obtained from the Rafsanjan Cohort Study (RCS), as a part of the prospective epidemiological research studies in IrAN (PERSIAN). (biomedcentral.com)
  • An observational analytical study was conducted cross-sectionally, using medical records of cholestasis patients treated at RSUP Prof. Dr. I.G.N.G Ngoerah, Denpasar, from January 2015 to May 2023. (isainsmedis.id)
  • A total of 513 adult subjects who had undergone coronary angiography were enrolled in the study. (medscimonit.com)
  • The effect of repeated blood donation on some biochemical values of healthy adult male blood donors in Calabar, Nigeria was studied. (scirp.org)
  • Our aim was to investigate the correlation of the level of liver enzymes with diabetes in the adult population of Rafsanjan. (biomedcentral.com)
  • Pretomanid in combination with bedaquiline and linezolid is approved for treating a limited and specific population of adult patients with extensively drug resistant, treatment-intolerant or nonresponsive multidrug resistant pulmonary TB. (worldpharmanews.com)
  • In the MS pooled analyses of Study 1 and Study 2, the decline in absolute FEV 1from baseline in patients treated with ZEPOSIA compared to patients who receivedUpper abdominal pain 2 1IFN beta-1a was 60 mL (95% CI: -100, -20) at 12 months. (usmedicine.com)
  • 2001]. However, due to several limitations of these studies, firm conclusions cannot be drawn [EPA 2012a]. (cdc.gov)
  • Based on the geographical distribution of Xinjiang's ethnic minorities in northwestern China, a representative county (six villages in Nalati Township, Xinyuan County) was selected and an ambispective cohort study was conducted on the local Kazakh population. (researchsquare.com)
  • Considering the limitation of studies investigating the relationship between T. gondii and cardiovascular biomarkers, this study was focused on assessing the association of T. gondii to nine cardiovascular biomarkers. (mdpi.com)
  • To identify and investigate the susceptibility genes of Kashin-Beck disease (KBD) in Chinese population. (escholarship.org)
  • Subjects with alcohol consumption of more than 20 g/day, other causes of chronic liver disease, morbid obesity, and diabetics were excluded from the study population. (springeropen.com)
  • A result of the studies emphasized that there was some parallelism between visceral adiposity and ischemic heart disease [ 5 ]. (springeropen.com)
  • The study utilized a self-administered questionnaire to collect data on socio-demographic characteristics, stimulant use, course of study, and academic performance. (bvsalud.org)
  • MORRISTOWN, N.J., Nov. 07, 2022 (GLOBE NEWSWIRE) -- Intercept Pharmaceuticals, Inc. (Nasdaq:ICPT), a biopharmaceutical company focused on the development and commercialization of novel therapeutics to treat progressive non-viral liver diseases, today announced additional supportive data from its pivotal Phase 3 REGENERATE study of obeticholic acid (OCA) in patients with liver fibrosis due to nonalcoholic steatohepatitis (NASH). (biospace.com)
  • These data will be presented on Monday, November 7, 2022, at The Liver Meeting®, the annual meeting of the American Association for the Study of Liver Diseases (AASLD) in Washington, D.C. (biospace.com)
  • We tested whether coding variants are the basis for linkage peaks of complex traits in 42 African-American (n = 596) and 90 Hispanic (n = 1,414) families in the Insulin Resistance Atherosclerosis Family Study (IRASFS) using Illumina HumanExome Beadchips. (escholarship.org)
  • Select patients for treatment with RYBREVANT based on the presence of EGFR exon 20 insertion mutations in tumor or plasma specimens [see Clinical Studies (14) ]. (drugs.com)
  • Evidence from a limited number of well-conducted reproductive studies in laboratory animals suggests that tetrachloroethylene is a potential female reproductive toxicant, resulting in decreased number of liveborn pups, increased pre-and post-implantation loss, and increased resorptions [ATSDR 2015]. (cdc.gov)
  • Objective: analysis and summary of the literature data and own studies on the possibility of using biomarkers of exposure and effect of organophosphorus compounds (OPCs), determination of immunological biomarkers of the effect under exposure to OPCs that cause delayed neurotoxicity (DN). (kiev.ua)
  • Another recent Danish study showed similar result (cumulative incidence of 6.0% after 10 years) 10 . (nature.com)
  • We therefore performed a cross-sectional study in the town of Campogalliano (Modena, Italy), within the context of the Dionysos Project. (nih.gov)
  • In a population of psychiatric patients, research evidence has shown the usefulness of biological measures in the detection of alcohol use disorders when compared with patient self-report. (medscape.com)
  • 56% of patients underreported alcohol use as evaluated by carbohydrate-deficient transferrin (CDT), and 37% of patients underreported alcohol use as evaluated by CDT + gamma glutamyltransferase (GGT). (medscape.com)
  • Multiple studies on medical inpatients and surgical patients in university and community hospitals, as well as outpatients in internal medicine and family medicine practices, show a low recognition rate and an even poorer treatment rate. (medscape.com)
  • This study aimed to assess the risk and predictors of HCC in Korean patients with alcoholic cirrhosis by using competing risk analysis. (nature.com)
  • In this study, we sought to perform a competing-risk analysis for predicting the risk and predictors of HCC in alcoholic cirrhosis patients in Korea. (nature.com)
  • All patients included in our study have given written informed consent after explaining the procedures and before they participated in the study. (springeropen.com)
  • and at Least 1% Greater than IFN beta-1a in Patients with Multiple Sclerosis (Pooled MS aStudy 1 and Study 2) Increased Blood PressureIn MS Study 1 and Study 2, patients treated with ZEPOSIA had an average increase of approximately 1 to 2 mm Hg inMS Studies 1 and 2systolic pressure over patients who received IFN beta-1a, and no effect on diastolic pressure. (usmedicine.com)
  • Two patients treated with ZEPOSIA in MS Study 1 and one patient treated with interferon (IFN)(n=882)(n=885) beta-1a in Study 2 experienced a hypertensive crisis that was not clearly influenced by a concomitant medication. (usmedicine.com)
  • We hope we continue to see more development of antibacterial drugs for treating serious or life-threatening infections in limited populations of patients with unmet medical needs. (worldpharmanews.com)
  • The safety and effectiveness of Pretomanid, taken orally in combination with bedaquiline and linezolid, was primarily demonstrated in a study of 109 patients with extensively drug-resistant, treatment‑intolerant or non-responsive multidrug-resistant pulmonary TB (of the lungs). (worldpharmanews.com)
  • Pretomanid is the second drug to be approved under the Limited Population Pathway for Antibacterial and Antifungal Drugs, or LPAD pathway, established by Congress under the 21st Century Cures Act to advance development and approval of antibacterial and antifungal drugs to treat serious or life-threatening infections in a limited population of patients with unmet need. (worldpharmanews.com)
  • An additional analysis of the subset of patients in the ITT population who had evaluable biopsies at baseline and Month 18 (n=747) was conducted within each treatment arm to show improvement, worsening or no change in fibrosis stage. (biospace.com)
  • Following the original analysis of the ITT population in 2019, an additional 676 patients became eligible for Month 18 biopsies prior to a protocol change in REGENERATE that eliminated this biopsy requirement. (biospace.com)
  • RÉSUMÉ Tous les patients de sexe masculin soignés en psychiatrie et en médecine générale adressés à deux hôpitaux de Basra (Iraq) de septembre 2000 à avril 200l ont été soumis à un dépistage de l'alcoolisme par le test AUDIT (Alcohol Use Disorder Identification Test). (who.int)
  • One hundred and fifty three (153) healthy repeat blood donors and 90 first time blood donors constituted the study population. (scirp.org)
  • A reduction in the values of some lipid profiles and high GGT activity is associated with repeated blood donations in this study population. (scirp.org)
  • R. S. Bharadwaj, "A Study of Lipid Profiles among Male Voluntary Blood Donors in Chennai City," Indian Journal of Community Medicine, Vol. 30, No. 1, 2005, pp. 1-5. (scirp.org)
  • T. Pekka and R. Salonen, "Cohort Study of Relationship between Donating Blood and the Risk of Myocardial Infarction," British Medical Journal, Vol. 314, No. 7083, 1997, pp. 793-794. (scirp.org)
  • Computed tomography (CT) scanning and MRI studies of the brain may be important in ruling out intracranial lesions when the diagnosis of hepatic encephalopathy is in question. (medscape.com)
  • This study was conducted to investigate the relationship of obesity and lifestyle to health status among Korean men in the Health Screen Examinees. (sch.ac.kr)
  • However, there was a significant relationship between the course of study and the occurrence of BFS. (bvsalud.org)
  • Further study revealed that pterostilbene played a therapeutic role in restoring energy supply, rebalancing neurotransmitters, reducing abnormal polyamine accumulation and phospholipid metabolism. (bvsalud.org)
  • One patient in MSaminotransferase increased, hepatic enzyme increased, abnormal liver function test, and increased transaminases.Study 1 discontinued ZEPOSIA because of dyspnea. (usmedicine.com)
  • The design of the study was approved by the ethical committee of the faculty of medicine, Ain Shams University, and was following the 1975 Helsinki declaration. (springeropen.com)
  • [ 38 ] Replication of such research in a primary care population is needed to show that biological measures aid the primary care clinician in detecting alcohol use disorders. (medscape.com)
  • This study was conducted in accordance with the Helsinki Declaration and was approved by the ethics and research committee of the Federal University of Health Sciences of Porto Alegre (UFCSPA), RS, Brazil, under the number 5203619. (wjgnet.com)
  • The present study is a cross-sectional research including 9991 adults participated via sampling. (biomedcentral.com)