• [ 3 ] The differential diagnosis of polyuria includes central diabetes insipidus, congenital or acquired nephrogenic diabetes insipidus, psychogenic polydipsia, high protein or hyperglycemic osmotic diuresis, salt-wasting nephropathies, mixed polyuria due to excess solute and water intake, and postobstructive diuresis following recovery from urinary obstruction. (medscape.com)
  • [ 3-14 ] Osmotic diuresis, driven by high protein intake, is typically encountered in hospitalized patients fed with exogenous protein administered by the enteral or parenteral route. (medscape.com)
  • Polyuria is caused by osmotic diuresis secondary to hyperglycemia. (medscape.com)
  • Answer: Kidney cannot reabsorb all of the glucose causing osmotic diuresis. (flashcardmachine.com)
  • Additionally, high amounts of solutes within the renal tubules cause a passive osmotic diuresis (solute diuresis) and thus an increase in urine volume. (msdmanuals.com)
  • Glucose-induced osmotic diuresis in diabetes mellitus is further increased with use of sodium-glucose cotransporter 2 inhibitors (SGLT2i) that lower plasma glucose levels by inhibiting renal glucose reabsorption and increasing renal glucose excretion. (msdmanuals.com)
  • can have an osmotic diuresis. (msdmanuals.com)
  • Consequently, in bitches with pyometra, factors other than osmotic diuresis appear to be mainly responsible for the reduction in concentrating ability and polyuria. (biomedcentral.com)
  • The water is drawn out by osmotic diuresis secondary to excess glucose in the urine. (shrinksinsneakers.com)
  • DKA patients are severely dehydrated due to osmotic diuresis from their hyperglycemic state. (iem-student.org)
  • When glucose passes through urine, it draws more water into urine due to a phenomenon called (osmotic diuresis). (doctor-explains.com)
  • However, it seems more likely that volume expansion (due to initial sodium retention) and a urea osmotic diuresis (as the daily urea load is excreted by fewer functioning nephrons), due in part to solute intake, play a more important role in the persistent urine output. (ecogateclinic.com)
  • As the osmotic diuresis continues, the intravascular volume is profoundly depleted, which further decreases renal perfusion and the ability of the kidneys to remove glucose from the blood. (ems1.com)
  • Sodium, potassium, phosphate and magnesium are typically lost during the osmotic diuresis leading to electrolyte imbalances. (ems1.com)
  • Based on information recorded in the diary, a physician can classify the patient as having global polyuria, nocturnal polyuria, or bladder storage problems. (wikipedia.org)
  • citation needed] Nocturnal polyuria is defined as an increase in urine production during the night but with a proportional decrease in daytime urine production that results in a normal 24-hour urine volume. (wikipedia.org)
  • With the 24-hour urine production within normal limits, nocturnal polyuria can be translated to having a nocturnal polyuria index (NPi) greater than 35% of the normal 24-hour urine volume. (wikipedia.org)
  • Severe nocturnal enuresis secondary to polyuria can be an indication of onset of diabetes in young children. (medscape.com)
  • 4 Elevated BNP levels have been "independently associated with both the presence and the severity of nocturnal voiding and nocturnal polyuria in elderly patients. (empr.com)
  • This year, An-Sofie Goessaert from Ghent, Belgium, convinced the international jury with the presentation of her project entitled " Nocturnal polyuria in spinal cord injury patients and the effect of conservative measures on urine production " and reached the highest scoring. (bjuinternational.com)
  • She demonstrated in a prospective study on patients with spinal cord injury that compressive stockings have an effect on nocturnal urine production, increasing diuresis during daytime and decreasing it during sleep to nearly normal bladder capacity, which might allow to have undisturbed sleep and higher quality of life. (bjuinternational.com)
  • Compared to controls mice have polyuria without serious impairment in keeping regular electrolyte and acid-base stability [30]. (bioskinrevive.com)
  • In particular, the magnitude of postnatal diuresis, immaturity of kidney function, and insensible fluid loss is higher at lower gestational age (GA). Thus, it is important for the clinician caring for the neonate, especially very preterm (VPT) infants, to have an understanding of the basic physiologic mechanisms that regulate and maintain water and electrolyte balance. (medilib.ir)
  • It may be used with more potent diuretics when a greater diuresis is required while maintaining a more balanced serum electrolyte pattern. (janusinfo.se)
  • Solute-induced polyuria can be seen in hospitalized patients after a high solute load from exogenous protein administration or following relief of urinary obstruction. (medscape.com)
  • Polyuria can result in volume depletion, rapid fluctuations in serum sodium levels, and distension of the renal outflow tract due to high urinary output volume. (medscape.com)
  • Restriction of the daily solute load and water intake resulted in complete resolution of polyuria. (medscape.com)
  • However, there were no significant differences in number of dialysis sessions and time on dialysis therapy between the furosemide and placebo groups, even in the subgroup of patients reaching a 2-L/d diuresis. (marysfamilymedicine.org)
  • Although Amiloride Hydrochloride may be used alone, its principal indication is as concurrent therapy with thiazides or more potent diuretics in order to conserve potassium during periods of vigorous diuresis and during long-term maintenance therapy. (janusinfo.se)
  • We describe a case of polyuria due to high solute ingestion and excessive water intake leading to a mixed picture of solute and water diuresis. (medscape.com)
  • citation needed] Polyuria is excessive or an abnormally large production or passage of urine. (wikipedia.org)
  • 5 Additionally, redistribution and elimination of fluid from HF-induced edema further contribute to urinary frequency and excessive diuresis -especially nocturnally, when peripheral edema is resorbed in the supine position. (empr.com)
  • The diagnostic principles used in this teaching case illustrate the approach to the evaluation of polyuria in an outpatient setting. (medscape.com)
  • To verify the polyuria phenotype we performed additional metabolic evaluation further. (bioskinrevive.com)
  • Global polyuria occurs in response to increased fluid intake and is defined as urine outputs of greater than 40 mL/kg/24 hours. (wikipedia.org)
  • Taken together these data for the first time identify Aqp5 as a Dot1a potential transcriptional target and an Aqp2 binding partner and regulator and suggest that the upregulated Aqp5 may contribute to polyuria possibly by impairing Aqp2 membrane localization in mice and in patients with diabetic nephropathy. (bioskinrevive.com)
  • Once an initial diuresis has been achieved, reduction in dosage may be attempted for maintenance therapy. (janusinfo.se)
  • In hepatic cirrhosis with ascites, Amiloride Hydrochloride usually provides adequate diuresis, with diminished potassium loss and less risk of metabolic alkalosis, when used alone. (janusinfo.se)
  • Polyuria, defined as daily urine output in excess of 3.0 to 3.5 L/d, can occur due to solute or water diuresis. (medscape.com)
  • Polyuria is usually viewed as a symptom or sign of another disorder (not a disease by itself), but it can be classed as a disorder, at least when its underlying causes are not clear. (wikipedia.org)
  • Increased production and passage of urine may also be termed diuresis. (wikipedia.org)
  • Infusion therapy was initiated to decrease the azotemia, to improve the diuresis and to stimulate the passage of the uroliths through the ureters. (ugent.be)
  • After diuresis has been achieved, the dosage may be reduced by 5mg increments to the least amount required. (janusinfo.se)
  • If necessary, dosage of both agents may be increased gradually until there is effective diuresis. (janusinfo.se)
  • Determination of the daily excreted urinary osmoles may yield important clues to the cause of polyuria and should be included in the routine workup of polyuria. (medscape.com)
  • Reduced expression and/or apical localization of Aqp2 under pathological conditions (i.e. nephrosis hypokalemia and mutations) results in polyuria. (bioskinrevive.com)
  • After birth, there is a physiologic diuresis of ECF resulting in a weight loss during the first week of life. (medilib.ir)
  • The magnitude of diuresis and relative weight loss decreases with increasing GA. Normal weight loss varies between infants and may be as much as approximately 10 to 15 percent of birth weight in preterm and 4 to 7 percent of birth weight for term breastfed infants in the first day of life [ 2 ]. (medilib.ir)
  • The postnatal diuresis is approximately 1 to 3 mL/kg per hour in term infants and is greater in preterm infants. (medilib.ir)