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  • enzymology
  • In enzymology, a xanthan lyase (EC 4.2.2.12) is an enzyme that catalyzes the chemical reaction of cleaving the beta-D-mannosyl-beta-D-1,4-glucuronosyl bond on the polysaccharide xanthan. (wikipedia.org)
  • In enzymology, a chondroitin B lyase (EC 4.2.2.19) is an enzyme that catalyzes the chemical reaction Eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (deltaUA-GalNAc-4S). (wikipedia.org)
  • In enzymology, an oligogalacturonide lyase (EC 4.2.2.6) is an enzyme that catalyzes the chemical reaction 4-(4-deoxy-beta-D-gluc-4-enuronosyl)-D-galacturonate ⇌ {\displaystyle \rightleftharpoons } 2 5-dehydro-4-deoxy-D-glucuronate Hence, this enzyme has one substrate, 4-(4-deoxy-beta-D-gluc-4-enuronosyl)-D-galacturonate, and one product, 5-dehydro-4-deoxy-D-glucuronate. (wikipedia.org)
  • In enzymology, a glucuronan lyase (EC 4.2.2.14) is an enzyme that catalyzes the chemical reaction of eliminative cleavage of (1->4)-beta-D-glucuronans. (wikipedia.org)
  • In enzymology, a levan fructotransferase (DFA-IV-forming) (EC 4.2.2.16) is an enzyme that catalyzes the chemical reaction Produces di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. (wikipedia.org)
  • In enzymology, a pectin lyase also known as pectolyase is a naturally occurring pectinase a type of enzyme that degrades pectin. (wikipedia.org)
  • In enzymology, a poly(beta-D-mannuronate) lyase (EC 4.2.2.3) is an enzyme that catalyzes the chemical reaction Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. (wikipedia.org)
  • In enzymology, a chondroitin AC lyase (EC 4.2.2.5) is an enzyme that catalyzes the chemical reaction Eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. (wikipedia.org)
  • PMID
  • One such enzyme is hyaluronate lyase, a Streptococcal surface enzyme that degrades hyaluronan and chondroitin, thereby helping to spread the bacteria throughout host tissues [ PMID: 14523022 ]. (ebi.ac.uk)
  • protein
  • however, whether this protein is a lyase has yet to be determined. (cazypedia.org)
  • Opportunistic pathogens such as Pseudomonas aeruginosa and Stenotrophomonas maltophilia colonize the lungs of cystic fibrosis patients and secrete an extracellular matrix of protein, DNA, and polysaccharides which acts as a diffusion barrier against dehydration, phagocytosis, and antibiotic treatment. (lehigh.edu)
  • Substrate
  • In an effort to understand the potential role that two putative alginate lyases (Smlt1473 and Smlt2602) from S. maltophilia may play in bacterial virulence, each enzyme was heterologously expressed in Escherichia coli, purified in a one-step fashion via affinity chromatography, and assayed for catalytic activity as well as substrate specificity for a range of polysaccharides. (lehigh.edu)
  • residues
  • Xanthan is a polysaccharide secreted by several different bacterial taxa, such as the plant pathogen Xanthomonas campestris, and it consists of a main linear chain based on cellulose with side chains attached to alternate glucosyl (glucose) residues. (wikipedia.org)
  • Aspergillus
  • The first report on retting of sunn hemp (Crotalaria juncea) by pectin lyase produced by Aspergillus flavus MTCC 7589 was published in 2008 but this aspect of pectin lyases needs to be extensively investigated further. (wikipedia.org)
  • Mechanism
  • Pectin lyases are the only known pectinases capable of degrading highly esterified pectins (like those found in fruits) into small molecules via β-elimination mechanism without producing methanol (which is toxic), in contrast with the combination of PG and PE, which are normally found in commercial products. (wikipedia.org)
  • mutant
  • The result was the successful engineering of a completely unique mutant lyase that was exolytically active against both alginate and poly-β-D-glucuronic acid. (lehigh.edu)
  • domain
  • Hyaluronate lyase ( EC:4.2.2.1 ) is a four-domain enzyme containing an N-terminal carbohydrate-binding domain, a spacer domain, a catalytic domain, and a C-terminal domain that modulates access to the catalytic cleft of the enzyme. (ebi.ac.uk)
  • include
  • Other names in common use include heparin-sulfate eliminase, heparitin-sulfate lyase, heparitinase I, and heparitinase II. (wikipedia.org)
  • plant
  • We have also shown that the different topologies displayed by xylan binding modules reflect the variation in the context of this polysaccharide within the plant cell wall. (uga.edu)
  • complex
  • I am interested in glycoside hydrolases, which hydrolyse the glycosidic bonds that link sugar monomers in polysaccharides, and glycosyltransferases, which catalyze the synthesis of glycosidic bonds and thus the formation of complex carbohydrates or glycoconjugants. (uga.edu)
  • Most of the latter are generalists and consume red, green, and brown macroalgae, three distinct lineages characterized by a specific composition in complex polysaccharides, which represent half of their biomass. (beds.ac.uk)
  • known
  • Pectin lyases are the only known pectinases capable of degrading highly esterified pectins (like those found in fruits) into small molecules via β-elimination mechanism without producing methanol (which is toxic), in contrast with the combination of PG and PE, which are normally found in commercial products. (wikipedia.org)