• adhesion
  • In this study, we investigated the molecular mechanisms of a novel marine bacterial polysaccharide EPS11 which exerts its cytotoxic effects through affecting cancer cell adhesion and anoikis. (mdpi.com)
  • The physical and chemical characteristics of bacterial cells can be affected by EPS composition, influencing factors such as cellular recognition, aggregation, and adhesion in their natural environments. (wikipedia.org)
  • pathogens
  • Thus, a better understanding of the mechanisms involved in the generation, ontogeny, production, and selection of B cells bearing Abs with Ag binding sites specific to polysaccharides and T-independent Ags is needed to optimize the design and ontogenetic timing of vaccines directed against pathogens bearing these types of immunodominant Ags. (jimmunol.org)
  • meningitis
  • As an exclusively human pathogen it is the main cause of bacterial meningitis in children and young adults, causing developmental impairment and death in about 10% of cases. (wikipedia.org)
  • It causes the only form of bacterial meningitis known to occur epidemically , mainly Africa and Asia. (wikipedia.org)
  • binds
  • For example, the human symbiont Bacteroides fragilis produces polysaccharide A (PSA), which binds to toll-like receptor 2 (TLR-2) on CD4+ T cells. (wikipedia.org)
  • immune
  • 2004) Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system. (springer.com)
  • PRP covalently linked to a protein carrier was found to elicit a greater immune response than the polysaccharide form of the vaccine. (wikipedia.org)
  • Growth
  • EPSs are the construction material of bacterial settlements and either remain attached to the cell's outer surface, or are secreted into its growth medium. (wikipedia.org)
  • Furthermore, the EPS layer acts as a nutrient trap, facilitating bacterial growth. (wikipedia.org)
  • cells
  • In bacterial colonies, Pam is associated with an extracellular polysaccharide (EPS)-like matrix, and modifies the ability of wild-type cells to attach to an artificial surface. (beds.ac.uk)
  • Since optimal contact between B cells and T cells is required (via MHC II) to maximize antibody production, it is reasoned that the conjugate vaccine allows B cells to properly recruit T cells, this is in contrast to the polysaccharide form in which it is speculated that B cells do not interact optimally with T cells leading to the TI interaction. (wikipedia.org)
  • Structure
  • This cellular exoskeleton is the main structure responsible for the cell shape and the mechanical strength and elasticity of the bacterial envelope [ 10 ]. (mdpi.com)
  • cell
  • Mice respond to many polysaccharides in a T cell-independent manner, with the rapid production of an oligoclonal Ab response consisting primarily of IgM and IgG3 Abs ( 5 - 7 ). (jimmunol.org)
  • indicative that memory B cell formation is also improved over that of the polysaccharide form. (wikipedia.org)