• Microsatellites are commonly used as a molecular markers especially for identifying the relationship between alleles Polymorphisms have been discovered in multiple XPD exons. (wikipedia.org)
  • Microsatellite markers, or short tandem repeats (STR), are polymorphic DNA loci containing repeated nucleotide sequences, typically from 2 to 7 nucleotides per unit. (igbiosystems.com)
  • The vast amount of data emerging for thousands of microsatellite markers across organisms makes microsatellite analysis a widely accepted tool for linkage and association studies, and also for identifying individual organisms (i.e., human identification or HID). (igbiosystems.com)
  • In human and animal medicine, several molecular techniques have been developed to investigate the epidemiology of transmissible agents ( 11 - 15 ), such as multilocus sequence typing (MLST) analysis or mini/microsatellite length polymorphism using short tandem-repeat markers. (cdc.gov)
  • For the microsatellites, the ABI Prism Linkage Mapping Set version 2, with 402 microsatellite markers, was used, and, for the SNPs, the Early Access Affymetrix Mapping 10K array was used. (elsevierpure.com)
  • The greatest gain provided by the SNP markers was a large increase in the linkage information content, with an average information content of 61% for the SNPs, versus an average of 41% for the microsatellite markers. (elsevierpure.com)
  • The strengths and weaknesses of microsatellite versus SNP markers are illustrated by the results of our genome linkage scans. (elsevierpure.com)
  • microsatellite markers are available for the species (Bro wn et al. (researchgate.net)
  • A number of markers are now available to detect nuclear DNA polymorphisms. (intechopen.com)
  • In genetic diversity studies, the most frequently used markers are microsatellites. (intechopen.com)
  • To assess if the behavioral difference between the family and kenneled dogs could be due to genetic divergence of these two populations and/or to lower genetic diversity of the kenneled dogs, we analyzed their genetic structure using 11 microsatellite markers. (frontiersin.org)
  • In wheat, microsatellite markers show a higher level of polymorphism than RFLP or RAPD markers. (usda.gov)
  • Our objectives were to determine the abundance of trinucleotide microsatellites and the rate at which they can be developed into informative markers. (usda.gov)
  • Preliminary results indicate that high quality trinucleotide microsatellite markers can be developed in wheat. (usda.gov)
  • Such ancestry informative markers (AIMs), have rarely been developed for endangered species such as tigers utilizing single nucleotide polymorphisms (SNPs). (nature.com)
  • 2000 ). Traditionally, upon the advent of Polymerase Chain Reaction (PCR) technology, genetic variation within wild populations used to be determined either employing a handful of neutral microsatellite markers or assessing mitochondrial DNA sequences (Chapman et al. (nature.com)
  • Genetic resources of macroalgae: Development of an efficient method using microsatellite markers in non-model organisms. (sb-roscoff.fr)
  • Two pairs of co-dominant polymorphisms were detected, and were converted into sequence-specific PCR markers desirable for routine marker implementation. (cropscience.org.au)
  • A total of 720 individuals of 12 indigenous chicken populations, geographically localized in Southern China were genotyped for 30 microsatellite markers in polymerase chain reaction (PCR) to evaluate the genetic variation and genetic distance between populations. (scialert.net)
  • These markers reveal microsatellite (SSR) differences or more recently single nucleotide polymorphism (SNP) differences. (uwi.edu)
  • The molecular screening through microsatellite markers showed low polymorphism (0.019) between the samples analyzed. (nepjol.info)
  • Pseudomolecules as well as unmapped scaffolds were used for the bulk mining of SSR markers and for the construction of the first globe artichoke microsatellite marker database. (researchgate.net)
  • Abstract - The genetic variability of Apis mellifera ligustica was screened throughout the Italian peninsula and Sardinia with eight polymorphic microsatellite loci. (apidologie.org)
  • Population differentiation and relationships among 6 natural rockfish populations collected from northern coastal seas around Japan were assayed using microsatellite DNA loci. (eurekamag.com)
  • Short tandem repeats (STRs), also called microsatellites, are polymorphic DNA loci present throughout the genome and used for linkage mapping studies, association studies, and identification of organisms. (igbiosystems.com)
  • Four loci were analyzed with 1 minisatellite (MS4) and 3 microsatellites (MS1, MS3, and MS7). (cdc.gov)
  • exhibit low levels of polymorphism in our samples (3.13 alleles per locus for eight successfully amplified loci) and 38% of loci tested present more than two alleles per primer set (data not shown). (bioone.org)
  • A total of 47 new microsatellite loci were developed and tested for polymorphism and informativeness using the MARC bovine mapping family. (usda.gov)
  • Of the 30 microsatellite loci, number of alleles per locus (Na) and effective number of alleles per locus (Ne) ranged from 4 to 11 and 2.157 to 8.019, respectively. (scialert.net)
  • Haplotypes within haplogroups were analyzed with seven microsatellite loci. (blogspot.com)
  • Examples include: Single nucleotide polymorphisms (SNPs) are a single nucleotide changes that happen in the genome in a particular location. (wikipedia.org)
  • To investigate the possibility of a founder effect in these four families, we conducted haplotype analysis, and 14 single nucleotide polymorphisms (SNPs) throughout the SLC26A4 gene were genotyped. (nih.gov)
  • In this study, we compare genome linkage scans using microsatellites with those using single-nucleotide polymorphisms (SNPs), performed in 467 men with prostate cancer from 167 families. (elsevierpure.com)
  • The objectives of this research were to assess (1) the degree of Simple Sequence Repeats (SSR) DNA length polymorphism in melon (Cucumis melo L.) and other species within the Cucurbitaceae family and (2) the possibility of utilizing SSRs flanking primers from single species to other genera or species of Cucurbitaceae. (agri.gov.il)
  • Microsatellites are repeats of 1-6 base pairs of DNA sequence. (wikipedia.org)
  • Five of the seven SSRs detected length polymorphism among the 8 melon genotypes. (agri.gov.il)
  • 2001) reported the microsatellite-anchored fragment length polymorphism (MFLP) method. (cropscience.org.au)
  • DNA was extracted from fresh-frozen tissues of 344 patients with CRC who underwent curative surgery and genotyping analyses were performed using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. (iiarjournals.org)
  • Gene polymorphisms can occur in any region of the genome. (wikipedia.org)
  • For example, repetitive elements of the Alu and LINE1 families cause polymorphisms in human genome. (wikipedia.org)
  • Retrospective Definition of Clostridioides difficile PCR Ribotypes on the Basis of Whole Genome Polymorphisms: A Proof of Principle Study. (applied-maths.com)
  • This unusually high incidence was investigated by sequence analysis at the internal transcribed spacer rDNA locus and then by 3 microsatellites and 1 minisatellite for multilocus genotyping. (cdc.gov)
  • Locus refinement was undertaken with single nucleotide polymorphism (SNP) microarray analysis. (molvis.org)
  • The single nucleotide polymorphism microarray analysis excluded a shared founder haplotype between the families and refined the locus to 3.1 Mb. (molvis.org)
  • Four of the seven SSRs detected polymorphism among the 11 cucumber genotypes, with gene diversity values ranging between 0.18 and 0.64. (agri.gov.il)
  • The majority of polymorphisms are silent, meaning they do not alter the function or expression of a gene. (wikipedia.org)
  • In addition, we discuss reports on the interactions of OXT and AVP receptor genes and genes involved in other pathways (such as those of dopamine, serotonin, and reelin), as well as research that has shed some light on the impact of gene polymorphisms on the volume, connectivity, and activation of specific neural structures, differential receptor expression, and plasma levels of the OXT and AVP peptides. (frontiersin.org)
  • A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability. (cdc.gov)
  • en individuals (and populations) molecular coancestry coefficients (f ij ), the Kinship distance (D k ) at individual and population levels. (ucm.es)
  • There have been a number of studies looking into various polymorphisms of asthma-associated genes and how those polymorphisms interact with the carrier's environment. (wikipedia.org)
  • For CRC, polymorphisms in the genes involved in tumor progression, apoptosis, and angiogenesis have already been extensively studied for their association with cancer susceptibility and prognosis ( 1 - 7 ). (iiarjournals.org)
  • Y haplogroups were identified through typing of biallelic polymorphisms in the nonrecombining part of the chromosome. (blogspot.com)
  • Linkage was determined by genotyping microsatellite makers and calculating logarithm of the odds (LOD) scores. (molvis.org)
  • Methylation, expression, microsatellite marker, single nucleotide polymorphism array and trio whole-exome sequencing analyses were conducted. (bmj.com)
  • Once amplified, polymorphisms and mutations in the sequence can be detected by DNA sequencing, either directly or after screening for variation with a method such as single strand conformation polymorphism analysis. (wikipedia.org)
  • The single nucleotide polymorphism is the most common form of genetic variation. (wikipedia.org)
  • Asp312Asn and Lys751Gln are the two common polymorphisms of XPD that result in a change in a single amino acid. (wikipedia.org)
  • Public databases were screened to develop ultra-efficient microsatellite (STR) and single nucleotide polymorphism (SNP) panels for parentage assignment. (europa.eu)
  • Reproduction of hens selected for chosen egg quality traits vs. changes of some microsatellite allele frequencies. (wpsa.com)
  • This project is original, since the interest in melanin-based colour traits and genetic colour polymorphism has recently grown. (unil.ch)
  • Since the introgression of foreign alleles into both endemic natural and commercial A. m. ligustica populations, can be detected and monitored by microsatellite analysis, the results provide a reference data set for future local biodiversity conservation and other controlled breeding programs. (apidologie.org)
  • The results provided evidence of the applicability of microsatellite to determining the genetic relatedness among different Chinese indigenous chicken populations and evaluating of genetic variations. (scialert.net)
  • Although a large body of research, ranging from rodents to humans, has reported on the effects of OXT and AVP administration on affiliative and trust behaviors, and has highlighted the genetic contributions of OXT and AVP receptor polymorphisms to both social behaviors and to diseases related to social deficits, the consequences of peptide administration on psychiatric symptoms, and the impact of receptor polymorphisms on receptor function, are still unclear. (frontiersin.org)
  • A rule of thumb that is sometimes used is to classify genetic variants that occur below 1% allele frequency as mutations rather than polymorphisms. (wikipedia.org)
  • Polymorphisms can be identified in the laboratory using a variety of methods. (wikipedia.org)
  • First reported microsatellite study on wild Belizean Criollo cacao. (uwi.edu)
  • The studies provided mixed results, from concluding individuals who are homozygous for the Asn allele or homozygous for the Gln allele had an increased risk of developing lung cancer, to finding no statistical significance between smokers who have either allele polymorphism and their susceptibility to lung cancer. (wikipedia.org)
  • The polymorphism information content (PIC) has values between 0.560 and 0.641. (scialert.net)
  • Such weakly structured stem models explain patterns of polymorphism that had previously been attributed to contributions from archaic hominins in Africa2-7. (bvsalud.org)
  • All microsatellites were found to be polymorphic. (scialert.net)
  • The evolution, maintenance and adaptive function of genetic colour polymorphism in birds. (unil.ch)
  • Research continues to be conducted to determine the relationship between XPD polymorphisms and lung cancer risk. (wikipedia.org)
  • A database, called "Cynara cardunculus MicroSatellite DataBase" (CyMSatDB) was developed to provide a searchable interface to the SSR data. (researchgate.net)