Polymorphism asian continental ancestry group. Medical search. Frequent questions

METHODOLOGY: Lead single nucleotide polymorphism (SNPs) at 37 T2D-risk loci attaining genome-wide significance in Europeans were genotyped in 878 T2D cases and 1523 normoglycaemic controls from Sri Lanka. (ox.ac.uk)
We report a meta-analysis of four large genome-wide association studies of CAD, with ∼575,000 genotyped SNPs in a discovery dataset comprising 15,420 individuals with CAD (cases) (8,424 Europeans and 6,996 South Asians) and 15,062 controls. (ox.ac.uk)
Several single-nucleotide polymorphisms (SNPs) that may affect long-chain polyunsaturated fatty acid (LCPUFA) biosynthesis, the distribution of dietary PUFA, and their functional effects have been described in recent years (see this Guest Article ). (fatsoflife.com)
Currently, ancestry informative marker (AIM) panels have been widely utilized with up to a few hundred ancestry-informative single nucleotide polymorphisms (SNPs) to infer ancestry admixture. (omicsdi.org)
In this study, we conducted an analysis for association of single nucleotide polymorphisms (SNPs) and common haplotypes of two candidate genes, RANK (receptor activator of the NF-κB) and RANKL (receptor activator of the NF-κB ligand), with AAM in 825 unrelated Chinese women. (hku.hk)
Stage 1 analysis examined ∼18.8 million SNPs and small insertion/deletion variants in 129,913 individuals from four ancestries (European, African, Asian, and Hispanic) with follow-up analysis of promising variants in 480,178 additional individuals from five ancestries. (ox.ac.uk)
Standard GWASs testing now is available, which can query over a million variants that differ in only a single DNA building block (i.e., single nucleotide polymorphisms [SNPs]), indexing variations in the human genome and thereby providing relatively easy access to an individual's genetic makeup (i.e., genotype). (nih.gov)
To demonstrate its capabilities, we compared the FST distributions of GenoChip SNPs to those of two commercial arrays for three continental populations. (blogspot.com)

The relationship between treatment response and genotype was assessed separately for Caucasians and Asians. (york.ac.uk)
In both groups, the most common alleles were A28, A27, and A29, and the A26/A26 genotype was significantly more common in the Ca group. (geneticsmr.com)
CONCLUSION: In the largest study performed to date, the PADI4 genotype was not a significant risk factor for RA in people of European ancestry, in contrast to Asian populations. (ox.ac.uk)
Conclusions: In a white population, MCV values were not associated with genotype polymorphisms of ADH1C. (uni-luebeck.de)

Studies on polymorphisms found in one cluster of closely-located genes coding for fatty acid desaturases (FADS), enzymes that play an important role in the biosynthesis of both omega-6 and omega-3 LCPUFA, are providing an interesting perspective on the interaction between traditional diets and the population genetic history of humans. (fatsoflife.com)
Humans exhibit colour vision variations due to genetic polymorphisms, with trichromacy being the most common, while some people are classified as dichromats. (bvsalud.org)
Considering that K1 gene polymorphisms of HHV-8-infected persons reflect the divergence accumulated during the early migrations of modern humans out of Africa ( 1 ), it is tempting to put the polymorphisms observed in the different subtypes into an evolutionary perspective with their geographic distribution. (cdc.gov)
According to Nicholas Wade, "Humans cluster into five continental groups or races, and within each race there are further subclusters. (thisviewoflife.com)
Given visually complex social relationships, humans presumably have always observed and speculated about the physical differences among individuals and groups. (daynal.org)

At 10 unique loci, distinct non-rare ancestry-specific variants colocalize within the same linkage disequilibrium block despite the significantly discordant effects for the proxy shared variants between the ethnic groups. (ox.ac.uk)
Studies that traverse ancestrally diverse populations may increase power to detect novel loci and improve fine-mapping resolution of causal variants by leveraging linkage disequilibrium differences between ethnic groups. (ox.ac.uk)
The inclusion of African ancestry samples may yield further improvements because of low linkage disequilibrium and high genetic heterogeneity. (ox.ac.uk)

We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes (T2D) in east Asian populations. (ox.ac.uk)
This study aims to establish whether common variants conferring T2D-risk in Europeans contribute to T2D-susceptibility in the South Asian population of Sri Lanka. (ox.ac.uk)
Investigation on the association between IL-10 C819T gene polymorphisms and susceptibility to gastric cancer. (geneticsmr.com)
Polymorphism in the third intron of the interferonγ gene is associated with susceptibility to multiple sclerosis. (geneticsmr.com)
BACKGROUND: Polymorphisms of the peptidylarginine deiminase type 4 (PADI4) gene confer susceptibility to rheumatoid arthritis (RA) in East Asian people. (ox.ac.uk)
Given the observed ethnic/racial disparities in diabetes prevalence, we hypothesized that some diabetes susceptibility alleles are present at higher frequency in African Americans than in European Americans, resulting in association between genetic ancestry and diabetes risk that is independent of its association with other non-genetic risk factors for type 2 diabetes. (emilkirkegaard.dk)
Thus we sought 1) to establish the association of genetic ancestry with diabetes and related quantitative traits in African Americans, after accounting for the non-genetic risk factors, and 2) to identify diabetes susceptibility loci by conducting a genome-wide admixture mapping scan. (emilkirkegaard.dk)

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. (ox.ac.uk)
Interethnic analyses of blood pressure loci in populations of East Asian and European descent. (ox.ac.uk)
We report 19 new genetic loci and ancestry-specific BP variants, conforming to a common ancestry-specific variant association model. (ox.ac.uk)
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. (ox.ac.uk)
We investigate the fine-mapping resolution of trans-ethnic fixed-effects meta-analysis for five type II diabetes loci, under various settings of ancestral composition (European, East Asian, African), allelic heterogeneity, and causal variant minor allele frequency. (ox.ac.uk)
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. (ox.ac.uk)
In summary, in community-based populations with more than 7,000 African Americans, we found that genetic ancestry is significant associated with type 2 diabetes above and beyond the effects of markers of SES, and we detected several suggestive loci that may harbor genetic variants modulating diabetes risk. (emilkirkegaard.dk)

We classified those articles on the basis of their samples into high-risk and low-risk populations and white and Asian ethnic groups. (ox.ac.uk)
Haplotype-based selection analysis further suggests that this is a striking example of two functional polymorphisms being strongly selected for in human populations in response to environmental stresses. (ox.ac.uk)
Positive Selection of an Indel Polymorphism in the FADS Gene Cluster May be Driving Long-Chain PUFA Biosynthetic Capacity in Specific Human Populations. (fatsoflife.com)
The population frequency of the indel (rs66698963) is remarkably different among human populations with the insertion being far more frequent in South Asians, Africans and some East Asian populations, and far less common in European and other East Asian populations. (fatsoflife.com)
For example, the incidence rate of liver cancer has been shown with substantial disparity between Hispanic, Asian and non-Hispanic white populations. (omicsdi.org)
RESULTS:In this study we designed an unique AIM panel that infers 3-way genetic admixture from three distinct and selective continental populations (African (AFR), European (EUR), and East Asian (EAS)) within evolutionarily conserved exonic regions. (omicsdi.org)
Glioma incidence is highest in non-Hispanic Whites, and to date, glioma genome-wide association studies (GWAS) to date have only included European ancestry (EA) populations. (elsevierpure.com)
We estimated global and local ancestry using fastStructure and RFMix, respectively, using 1,000 genomes project reference populations. (elsevierpure.com)
Because of extensive admixture among these various groups, the Brazilian population shows great variability in terms of Populations on different continents vary considerably in their skin pigmentation, phenotypic features, and genomic structure [2]. (cdc.gov)
The term race refers to the concept of dividing people into populations or groups on the basis of various sets of characteristics and beliefs about common ancestry. (daynal.org)

Here, we perform a multi-stage genome-wide association study for BP (max N = 289,038) principally in East Asians and meta-analysis in East Asians and Europeans. (ox.ac.uk)
CONCLUSION: Our data indicate that most T2D-risk variants identified in Europeans have similar effects in South Asians from Sri Lanka, and that systematic difference in common variant associations are unlikely to explain inter-ethnic differences in prevalence or presentation of T2D. (ox.ac.uk)
BACKGROUND:Europeans and American Indians were major genetic ancestry of Hispanics in the U.S. These ancestral groups have markedly different incidence rates and outcomes in many types of cancers. (omicsdi.org)
Both polymorphisms are largely confined to Europeans, especially those from the north and east. (blogspot.com)
OK Oleg, but almost all modern day Europeans, especially those from across Northern and Eastern Europe, do derive a lot of their ancestry from Bronze Age steppe groups closely related to the Yamnaya people of the North Caspian. (blogspot.com)
For haplogroup R1b, we identified a previously unstudied "eastern" branch, R1b-GG400, found in East Europeans and West Asians and forming a brother clade to the "western" branch R1b-L51 found in West Europeans. (blogspot.com)
Smedley 1999) As Europeans encountered people from different parts of the world , they speculated about the physical, social, and cultural differences among various human groups. (daynal.org)
Meltzer 1993) Drawing on Classical sources and upon their own internal interactions - for example, the hostility between the English and Irish was a powerful influence on early thinking about the differences between people (Takaki 1993) - Europeans began to sort themselves and others into groups associated with physical appearance and with deeply ingrained behaviors and capacities. (daynal.org)

The most common allele of the tetranucleotide TTTA repeat polymorphism in the forth intron of CYP19 gene in Han Chinese women is 11R, which was different with the previous study in European Caucasians. (nel.edu)

The appearance of genetic polymorphisms, i.e. differences in the DNA nucleotide sequence between individuals, contributes to the opportunity for functional adaptation to specific environments that organisms may encounter. (fatsoflife.com)

The polymorphism was present as an insertion in cells derived from a group of Japanese individuals, but was completely absent (a deletion) in others, albeit with a lower frequency (hence called the minor allele). (fatsoflife.com)
The population frequency of the allele corresponding to the rs66698963 insertion (allele named I) or deletion (allele named D) was determined from genomic DNA extracted from human samples (blood, breast milk, and placenta) obtained from several participating institutions in the US and Canada (n=211, nearly all from Kansas City), as well as from a group of Asian Indians (n=76). (fatsoflife.com)
Common allele of the CYP19 tetranucleotide TTTA repeat polymorphism in this population of Han Chinese women was 11R. (nel.edu)
Here, we present Summix, a method to efficiently deconvolute ancestry and provide ancestry-adjusted allele frequencies (AFs) from summary data. (omicsdi.org)

Over many generations, the selection of beneficial traits associated with particular polymorphisms can lead to gradual changes in the frequency of specific genetic polymorphisms in a genetically-isolated population. (fatsoflife.com)

STRUCTURE is an algorithm designed to infer population structure (cluster individuals into ancestry groups) within a species (Pritchard, Stephens, and Donnelly 2000. (thisviewoflife.com)

Our results provide new evidence for the role of common ancestry-specific variants and natural selection in ethnic differences in complex traits such as BP. (ox.ac.uk)
These discoveries need to be evaluated in other major ancestral groups, to understand ethnic differences in predisposition, and establish whether these contribute to variation in T2D prevalence and presentation. (ox.ac.uk)
The effect of ancestry on any individual locus in the genome is likely to be modest, but in aggregate, differences in ancestry may contribute substantially to the observed ethnic disparity in risk of type 2 diabetes. (emilkirkegaard.dk)

This study reports a 22-bp nucleotide insertion-deletion (indel) genetic polymorphism that may be causally related to the control of gene expression of the fatty acid desaturases, enzymes that control the biosynthesis of long-chain polyunsaturated fatty acids (LCPUFA) from 18-carbon PUFA. (fatsoflife.com)

An ancestry informative marker panel design for individual ancestry estimation of Hispanic population using whole exome sequencing data. (omicsdi.org)
Subjects identified themselves as belonging to one of four major racial/ethnic groups (white, African American, East Asian, and Hispanic) and were recruited from 15 different geographic locales within the United States and Taiwan. (blogspot.com)
From left to right, the FBI assigns the above individuals to the following races: White, Black, Hispanic, Asian. (kss.org.pl)

The overall results were concordant in both ethnic groups. (ox.ac.uk)
However, often brutal conflicts between ethnic groups have existed throughout history and across the world, and racial prejudice against Africans also exists today in non-colonised countries such as China and Japan. (kss.org.pl)

We recently identified a polymorphism in exon 6 (A138G) of the gene encoding CD45 (PTPRC) that results in altered CD45 splicing. (ox.ac.uk)

the Ca group presented greater frequency of short alleles A13-A25, whereas the Ct group presented a higher frequency of long alleles. (geneticsmr.com)
We developed a framework for inference of germline variants from tumor panel sequencing, including imputation, quality control, inference of genetic ancestry, germline polygenic risk scores, and HLA alleles. (biomedcentral.com)

Blood-based single nucleotide polymorphism (SNP) analysis was performed. (cancerindex.org)
372 donors were genotyped using a custom precision medicine single nucleotide polymorphism (SNP) microarray. (nature.com)
In particular, three settings of ancestral composition were compared: (1) single ancestry (European), (2) moderate ancestral diversity (European and East Asian), and (3) high ancestral diversity (European, East Asian, and African). (ox.ac.uk)
METHODS: The PADI4_94 (rs2240340) single nucleotide polymorphism (SNP) was directly genotyped in a cohort of unrelated UK Caucasian patients with RA (n=3732) and population controls (n=3039). (ox.ac.uk)
Molecular data, in particular genome-wide single nucleotide polymorphism (SNP) markers, can complement historic and archaeological records to elucidate these past events. (biomedcentral.com)
STRUCTURE produces for individuals an estimate of the probability that a randomly chosen genetic marker (e.g. single tandem repeats, STR, or single nucleotide polymorphisms, SNP) from that individual originated from one of a set of ancestral groups. (thisviewoflife.com)
These results suggest that in African Americans, genetic ancestry has a significant effect on the risk of type 2 diabetes that are independent of the contribution of SES, but that no single locus with a major effect explains a large portion of the observed disparity in diabetes risk between African Americans and European Americans. (emilkirkegaard.dk)
The single-nucleotide polymorphisms that showed the most significant associations were tested for association with a second form of glaucoma, exfoliation-syndrome glaucoma. (prolekarniky.cz)

Although several methods exist to estimate ancestry in individual-level data, methods to estimate ancestry proportions in summary data are lacking. (omicsdi.org)
African Americans and Hispanics in the US have varying proportions of EA, African (AA) and Native American ancestries (NAA). (elsevierpure.com)
In unsupervised analyses, a Sardinian-specific ancestry component correlates with shared drift parameters with both the Neolithic farmers and Paleolithic hunter-gatherers, and is consistent with supervised estimates of ancestry proportions in which the Ogliastra individuals have higher Neolithic farmer and Paleolithic hunter-gatherer ancestries, while individuals from the rest of the island show an infusion of the pastoralist ancestry. (blogspot.com)

Air pollution impacts gene expression and pathways affecting cardio-metabolic and respiratory traits, when controlling for genetic ancestry. (nature.com)
After attributing a regional and/or continental ancestry to each individual using genome-wide polymorphism data, we are able to capture the effect of different environmental exposures on gene expression and health-related traits, while simultaneously controlling for genetic relatedness and migration. (nature.com)

Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent. (ox.ac.uk)

Data were technically validated using published algorithms to evaluate donor relatedness, ancestry, imputed HLA, and T1D genetic risk score. (nature.com)

There was little evidence for ancestry-specific associations, supporting the use of combined analyses. (ox.ac.uk)
Our simulations suggest that the European/Asian and European ancestry-only meta-analyses consistently attain similar fine-mapping resolution. (ox.ac.uk)
Model-based clustering and ancestry informative markers analyses suggested that this is due to taurine introgression. (biomedcentral.com)

Although no significant association was identified for the RANKL gene, three polymorphisms showed nearly significant (0.05 (hku.hk)

Chinese Americans constitute a subgroup of East Asian Americans which also constitute a subgroup of Asian Americans. (wikipedia.org)

INTRODUCTION: Most studies seeking common variant associations with type 2 diabetes (T2D) have focused on individuals of European ancestry. (ox.ac.uk)
Using continental reference ancestry, African (AFR), non-Finnish European (EUR), East Asian (EAS), Indigenous American (IAM), South Asian (SAS), we obtain accurate and precise estimates (within 0.1%) for all simulation scenarios. (omicsdi.org)
Conclusions: Our results indicate that European ancestry is a risk factor for cutaneous melanoma. (cdc.gov)
1) "In accordance with historical records, recent studies showed that AJ are genetically homogeneous with mixed European and Middle-Eastern ancestry and that the AJ population had undergone a severe bottleneck around 800ya followed by an extremely rapid expansion. (blogspot.com)
Medieval models of "race" mixed Classical ideas with the notion that humanity as a whole was descended from Shem , Ham and Japheth , the three sons of Noah , producing distinct Semitic ( Asian ), Hamitic ( African ), and Japhetic ( European ) peoples. (daynal.org)

In contrast with the positive selection of favorable adaptive polymorphisms, a genetic variant may also gradually disappear from a population if there is no survival advantage in having it. (fatsoflife.com)
In contrast to findings in Asians, macrocytosis does not seem to be an independent biomarker for esophageal cancer. (uni-luebeck.de)

A very important new article by a group of Greek and Chinese researchers provides the first quantitative assessment of mental processing in two groups of students, aged 8 to 14, belonging to the Caucasoid and Mongoloid races. (blogspot.com)
Conceptions of race, as well as specific ways of grouping races , vary by culture and over time, and are often controversial for scientific as well as social and political reasons. (daynal.org)

the people that they replaced in the Arctic have disappeared as a distinct group (some apparently made it to 1900 or so) but both the. (juliarauchfrei.at)

Association between interleukin-17 gene polymorphisms and the risk of laryngeal cancer in a Chinese population. (geneticsmr.com)
We showcase the feasibility and utility of our framework by analyzing 25,889 tumors and identifying the relationships between genetic ancestry, polygenic risk, and tumor characteristics that could not be studied with conventional on-target tumor data. (biomedcentral.com)
In addition, they suggest that genetic measured African ancestry contributes to the risk of type 2 diabetes via both genetic and non-genetic pathways. (emilkirkegaard.dk)

It is thought that Native Americans infected by subtype E and Pacific Islanders, including those infected by subtype D in the Japanese archipelago, originated from a common ancestral genetic stock in continental Asia. (cdc.gov)
Thus, we conducted a molecular epidemiology HHV-8 survey of the Buryat population, a major indigenous group in southern Siberia, to gain new insights into the origins, possibly common, of HHV-8 subtypes D and E. (cdc.gov)

From ∼ 1000 individuals of a founder population in Quebec, we reveal a substantial impact of the environment on the transcriptome and clinical endophenotypes, overpowering that of genetic ancestry. (nature.com)
Drawing from this founding population of individuals with largely French ancestry, we selected 1007 individuals to determine mechanisms by which genomes, the environment, and their interactions contribute to phenotypic variation. (nature.com)
68] On the other hand Edwards (2003) claims in his essay "Lewontin's Fallacy" that: "It is not true, as Nature claimed, that 'two random individuals from any one group are almost as different as any two random individuals from the entire world'" and Risch et al. (kss.org.pl)
The ancestral groups are not specified in advance, and the population membership of individuals is removed prior to analysis. (thisviewoflife.com)

Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness: a meta-analysis. (ox.ac.uk)
The inclusion of African ancestry samples in the meta-analysis leads to a marked improvement in fine-mapping resolution. (ox.ac.uk)
ADH1C genotyping was performed by PCR-based restriction fragment length polymorphism (PCR-RFLP) analysis from whole blood. (uni-luebeck.de)
The relation between MCV and ADH1C gene polymorphisms (ADH1C*1 and 1C*2) controlled for the amount of drinking, smoking, and age were investigated using both univariate and multivariate analysis. (uni-luebeck.de)

This CYP19 tetranucleotide TTTA repeat polymorphism is an ethnic and racial variant and moderately contributes to the pathogenesis of PCOS in the population of Han Chinese women. (nel.edu)

Some of the ancestry-specific association signals are also influenced by a selective sweep. (ox.ac.uk)
METHODS: We searched Medline for articles studying the association between the ACE I/D polymorphism and carotid IMT. (ox.ac.uk)
Evaluation of the association between the CYP19 Tetranucleotide (TTTA)n polymorphism and polycystic ovarian syndrome(PCOS) in Han Chinese women. (nel.edu)
The present study aims to evaluate the association between tetranucleotide TTTA repeat polymorphism in the CYP19 gene and PCOS among Han Chinese women. (nel.edu)
Hao C, Zhang N, Qu Q, Wang X, Gu H, Chen Z. Evaluation of the association between the CYP19 Tetranucleotide (TTTA)n polymorphism and polycystic ovarian syndrome(PCOS) in Han Chinese women. (nel.edu)
CASE-REPORT Association between an ACAN gene variable number tandem repeat polymorphism and lumbar disc herniation: a case control study. (geneticsmr.com)
We investigated the association between an aggrecan gene (ACAN) polymorphism and lumbar disc herniation (LDH). (geneticsmr.com)
Imputed data from the Wellcome Trust Case Control Consortium (WTCCC) was used to investigate the association of PADI4_94 with RA in an independent group of RA cases (n=1859) and controls (n=10 599). (ox.ac.uk)
Within groups with ≥40% AA (AFR ≥0.4 ), and ≥15% NAA (AMR ≥0.15 ), genome-wide association between local EA and glioma was evaluated using logistic regression conditioned on global EA for all gliomas. (elsevierpure.com)

The number of ancestral groups, K, is chosen to produce a best estimate of these probabilities, which are averaged over all genetic markers to assign a membership coefficient, namely a fraction of each individual's ancestry to one of the ancestral groups (Feldman 2010. (thisviewoflife.com)

We apply Summix to gnomAD v.2.1 exome and genome groups and subgroups, finding heterogeneous continental ancestry for several groups, including African/African American (∼84% AFR, ∼14% EUR) and American/Latinx (∼4% AFR, ∼5% EAS, ∼43% EUR, ∼46% IAM). (omicsdi.org)
GWASs analyze the presence of hundreds of thousands, or even millions, of polymorphisms across a person's genome. (nih.gov)

The polymorphism has a significant effect on baseline arachidonic acid levels, and on the product-precursor relationship for the omega-6 LCPUFA biosynthesis pathway. (fatsoflife.com)
S cone ratios (0.143:1 ± 0.002) had significant genetic variance with a heritability estimate of 43% but did not differ between sexes or age groups. (bvsalud.org)
Although a large part of South American zebu cattle also descend from taurine cows, we did not detect significant levels of taurine ancestry in these breeds, probably because of systematic backcrossing with zebu bulls. (biomedcentral.com)

It has long been known that many Mongoloid groups generally have higher IQ scores than Caucasoids, but the reasons for this difference have not been explained. (blogspot.com)
This leads scholars to conclude that, apart from the Mongoloid group that had made their way into Hokkaido, there must have been a second Mongoloid group (also originating from the ancestral Baikal Buryat people) who must have made their way from Siberia and into the southern Ryukyan part of the Japanese archipelago (and later Kyushu) via the other land bridge across the Tsushima Strait from the Korean peninsula. (dakarctu.com)
The first Mongoloid group is thought to have made their way through a corridor North of the Tibetan massif while the second Mongoloid group took the corridor South of the Himalayas heading in southerly direction into Kyushu or southeast Asia, then into Ryukyu islands. (dakarctu.com)

These findings, derived from an east Asian population, provide new perspectives on the etiology of T2D. (ox.ac.uk)

From the abstract: 'Precision prevention involves using the unique characteristics of a particular group to determine their responses to preventive interventions. (cdc.gov)

Studies that assessed the relationship between treatment response and genetic polymorphism of the serotonin transporter gene were eligible for inclusion. (york.ac.uk)

Chinese Americans are Americans of Chinese ancestry. (wikipedia.org)

Anatomy1

Diseases1

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Phenomena and Processes27

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena1

Humanities1

Information Science3

Named Groups12

Health Care8

Geographicals8

SNPs8

Genotype4

Humans5

Linkage disequilibrium3

Susceptibility7

Loci7

Populations10

Europeans8

Intron1

Nucleotide sequence1

Allele4

Genetically-isolated1

Infer1

Differences3

Insertion-deletion1

Hispanic3

Ethnic groups2

Exon1

Alleles2

Single8

Proportions3

Traits2

Variants1

Algorithms1

Analyses3

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Subgroup1

European5

Contrast2

Races2

Distinct1

Risk3

Common2

Individuals4

Analysis4

Contributes1

Association9

Ancestral groups1

Genome2

Significant3

Mongoloid3

Findings1

Characteristics1

Studies1

Americans1