• Tolvaptan
  • Unselective (mixed V1A/V2) Conivaptan V1A selective (V1RA) Relcovaptan V1B selective (V3RA) Nelivaptan V2 selective (V2RA) Lixivaptan Mozavaptan Satavaptan Tolvaptan Demeclocycline, a tetracycline antibiotic, is sometimes used to block the action of vasopressin in the kidney in hyponatremia due to inappropriately high secretion of vasopressin (SIADH), when fluid restriction has failed. (wikipedia.org)
  • It has been suggested that cardiovascular mortality may be reduced by selective V2RA such as tolvaptan in the higher risk group with kidney function impairment or severe congestive findings. (wikipedia.org)
  • volume
  • Kidney volume was assessed in T1-weighted magnetic resonance images collected at each study site and sent to a central reviewing facility. (clinicaltrials.gov)
  • At the central reviewing facility, blinded radiologists used proprietary software to measure the volume of both kidneys. (clinicaltrials.gov)
  • function
  • These receptors have a variety of functions, with the V1A and V2 receptors are expressed peripherally and involved in the modulation of blood pressure and kidney function respectively, while the V1A and V1B receptors are expressed in the central nervous system. (wikipedia.org)