• Gestational choriocarcinoma is a form of gestational trophoblastic neoplasia, which is a type of gestational trophoblastic disease (GTD), that can occur during pregnancy. (wikipedia.org)
  • Gestational choriocarcinoma can happen during and after any type of pregnancy event, though risk of the disease is higher in and after complete or partial molar pregnancies. (wikipedia.org)
  • Risk of disease may also be higher in those experiencing pregnancy at younger or older ages that average, such as below 15 years old or above 45 years old. (wikipedia.org)
  • Those with gestational choriocarcinoma may experience abnormal vaginal bleeding, abdominal pain, and have high levels of human chorionic gonadotropin (hCG), in addition to history of molar pregnancy or other metastatic cancer. (wikipedia.org)
  • Approximately 50% of those with gestational choriocarcinoma have experienced molar pregnancy, approximately 25% developed the disease after a regular, term pregnancy, and other situations have included history of ectopic pregnancy, where the pregnancy does not occur in the uterus. (wikipedia.org)
  • ABSTRACT To investigate the consequences of maternal malaria during late pregnancy, we conducted a preliminary study in the 2 hospitals in Al Hodeidah on 276 women who had uncomplicated vaginal deliveries. (who.int)
  • Data con- maternal (100/10 000 live births, 1991) and cerning personal and obstetric history, the infant (78.8/1000 live births, 1998) mortal- current pregnancy and pregnancy outcome ity rates have been recorded [ 8 ]. (who.int)
  • 4 , 5 , 6 Owing to these harmful effects, malaria in pregnancy is a significant driver of maternal and neonatal health in endemic areas. (glowm.com)
  • A Mediterranean diet with an enhanced consumption of extra virgin olive oil and pistachios improves pregnancy outcomes in women without gestational diabetes mellitus: a sub-analysis of the St. Carlos Gestational Diabetes Mellitus Prevention Study. (jamanetwork.com)
  • Elevated levels of maternal cortisol have been hypothesized as the intermediate process between symptoms of depression and psychosocial stress during pregnancy and adverse birth outcomes. (researchsquare.com)
  • Therefore, we examined associations between cortisol levels in the second trimester of pregnancy and risks of three common birth outcomes in a nested case-control study. (researchsquare.com)
  • The results of this study showed no suggestions of associations between maternal awakening cortisol levels in mid-pregnancy and adverse birth outcomes, except for an increased risk of SGA. (researchsquare.com)
  • Throughout pregnancy, maternal cortisol levels increase twofold, and cortisol crosses the placenta, accounting for 30-40% of the variability in fetal concentrations [10]. (researchsquare.com)
  • The relationships between falciparum and vivax malaria during pregnancy and the odds of gestational hypertension, pre-eclampsia, or eclampsia were examined using logistic regression amongst all women and then stratified by gravidity. (biomedcentral.com)
  • Primigravidae are also particularly susceptible to Plasmodium falciparum malaria in pregnancy with a peak of detection at 13-18 weeks' gestation in higher transmission settings [ 8 ], corresponding to the key period of fetal trophoblast invasion and maternal spiral artery transformation [ 9 ]. (biomedcentral.com)
  • CONCLUSION: These results suggest that the Gln223Arg variant in the maternal leptin receptor gene does not explain the association between placental leptin levels and birth weight, and is not associated with variation in maternal BMI in early pregnancy in our sample. (ox.ac.uk)
  • The fetal fraction in maternal plasma cfDNA increased with gestational age, serum pregnancy-associated plasma protein A (PAPP-A), β-hCG, and PlGF and decreased with increasing maternal BMI. (nih.gov)
  • WRAP-Association-between-fetal-abdominal-growth-trajectories-maternal-metabolite-signatures-early-in-pregnancy-and-childhood-growth-and-adiposity-Zammit-2022.pdf - Published Version - Requires a PDF viewer. (warwick.ac.uk)
  • Early pregnancy maternal blood and umbilical cord venous blood samples were collected for untargeted metabolomic analysis. (warwick.ac.uk)
  • These distinct phenotypes had matching feto-placental blood flow patterns throughout pregnancy, and different growth, adiposity, vision, and neurodevelopment outcomes in early childhood. (warwick.ac.uk)
  • Early pregnancy lipid biology associated with fetal abdominal growth trajectories is an indicator of patterns of growth, adiposity, vision, and neurodevelopment up to the age of 2 years. (warwick.ac.uk)
  • We searched the PubMed and MEDLINE up to August 20 2011 using combinations of the following keywords: vitamin D deficiency/insufficiency and pregnancy, reproduction, fertility/infertility, polycystic ovary syndrome, endometriosis, preeclampsia, gestational diabetes, preterm birth and bacterial vaginosis. (vitamindwiki.com)
  • Gestational diabetes mellitus occurs with the onset of pregnancy and is characterized by the inability of the pregnant patient to tolerate glucose. (healthhyme.com)
  • If women are at increased risk of gestational diabetes they will be offered a full test, which takes place during weeks 24-28 of pregnancy. (healthhyme.com)
  • Women may be screened for gestational diabetes at first antenatal appointment with doctor which takes place around weeks 8-12 of pregnancy. (healthhyme.com)
  • If women had gestational diabetes in a previous pregnancy, the GTT will be carried out at weeks 16-18 of pregnancy - or sooner, if indicated by the first blood glucose sample. (healthhyme.com)
  • The risk of complications is reduced if gestational diabetes is diagnosed and managed properly throughout pregnancy. (healthhyme.com)
  • We aimed to investigate the role of pregnancy-induced hypertension (PIH) in the association between ART and adverse neonatal outcomes. (biomedcentral.com)
  • Adult women (aged ≥ 18 years) with a singleton pregnancy in the National Vital Statistics System (NVSS) 2020 were enrolled in this retrospective cohort study. (biomedcentral.com)
  • Infertility is defined by the World Health Organization as the failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse, this definition is also supported by the American Medical Association, the European Society for Human Reproduction and Embryology, the International Committee for Monitoring Assisted Reproductive Technologies, and the American Society for Reproductive Medicine [ 1 ]. (biomedcentral.com)
  • PIH is one of the leading causes of maternal and neonatal adverse outcomes during pregnancy, including gestational hypertension and pre-eclampsia/eclampsia [ 16 ]. (biomedcentral.com)
  • Get the Fetal Life App for Apple and Android endorsed by the American Pregnancy Association. (americanpregnancy.org)
  • Originally, such studies focused on the significance of poor maternal health during pregnancy. (mdpi.com)
  • Gestational diabetes mellitus (GDM) is defined as glucose intolerance of variable degree with onset or first recognition during pregnancy. (medscape.com)
  • Gestational diabetes mellitus accounts for 90% of cases of diabetes mellitus in pregnancy, while preexisting type 2 diabetes accounts for 8% of such cases. (medscape.com)
  • The US Preventive Services Task Force (USPSTF) recommends screening for gestational diabetes mellitus after 24 weeks of pregnancy. (medscape.com)
  • Women with prediabetes identified before pregnancy should be considered at extremely high risk for developing gestational diabetes mellitus during pregnancy. (medscape.com)
  • The IGF2 (insulin-like growth factor 2) and H19 gene cluster plays an important role during pregnancy as it promotes both foetal and placental growth. (biomedcentral.com)
  • We assessed the sex-specific association between residential PM 2.5 exposure during pregnancy and the methylation level of CpG loci mapping to the IGF2 / H19 cluster, and identified prenatal vulnerability by investigating susceptible time windows of exposure. (biomedcentral.com)
  • In this study, we assessed the association between maternal PM 2.5 exposure during pregnancy and the DNA methylation level specific to IGF2/H19 gene cluster in cord blood collected at birth. (biomedcentral.com)
  • Background Limited studies have assessed the association of motor vehicle crashes (MVCs) during pregnancy with adverse maternal outcomes using a population-based nationwide dataset that covers all MVCs. (ncku.edu.tw)
  • Conclusions Women involved in MVCs during pregnancy were at increased risk of various adverse maternal outcomes, especially in those with severe MVCs and riding scooters at MVCs. (ncku.edu.tw)
  • Results from a recent study indicated that lowering the threshold for abnormal blood pressure in the second half of pregnancy from 140/90 mm Hg would not increase accuracy in identifying maternal or perinatal risk in patients. (drugtopics.com)
  • The American College of Cardiology (ACC) and American Heart Association (AHA) recommended lowering BP thresholds for HTN in 2017 to 120/80 mm Hg or more, but these recommendations have not been used in pregnancy HTN guidelines. (drugtopics.com)
  • The aim of our study is to present the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy and evaluate its impact on maternal and neonatal outcomes. (degruyter.com)
  • We documented the demographic features, clinical status, pregnancy characteristics and maternal and fetal outcomes. (degruyter.com)
  • Gestational age (GA) ranged from 10-42 weeks of pregnancy with mean GA calculated at 38 +3 weeks. (degruyter.com)
  • Her clinical interests include fetal and gynecologic imaging with ultrasound (US) and magnetic resonance (MR) and imaging of maternal complications of pregnancy. (utswmed.org)
  • This was a cross-sectional study with adult women, normal prepregnancy BMI, single pregnancy and gestational age at delivery ≥28 weeks, from the "Birth in Brazil" study, between 2011 and 2012. (scielosp.org)
  • Care by an interprofessional diabetes health-care team composed of a diabetes nurse educator, dietitian, obstetrician and endocrinologist/internist with expertise in diabetes, both prior to conception and during pregnancy, has been shown to minimize maternal and fetal risks in women with pre-existing type 1 and type 2 diabetes. (diabetes.ca)
  • We also identified cutoffs of gestational weight gain, based on pre-pregnancy BMI, associated with the risk of dystocia. (biomedcentral.com)
  • Accordingly, our aim in this study was to examine the association between BMI and the occurrence of dystocia among nulliparous women in Japan, as well as to identify the appropriate gestational weight gain cutoffs, based on the pre-pregnancy BMI, to lower the risk of dystocia. (biomedcentral.com)
  • An ILSI Europe workshop reviewed the key contributors leading to adverse outcomes in pregnancy and childhood, including gestational weight gain and nutrition. (karger.com)
  • Simple measures of gestational weight gain provide insufficient detail of the underlying physiological and metabolic adaptations occurring in pregnancy, and should be complemented by measures of body composition, metabolic and endocrine responses. (karger.com)
  • What are potential maternal complications of AT deficiency in pregnancy? (blogspot.com)
  • In pregnant women with laboratory evidence of Zika virus infection, serial ultrasound examination should be considered to monitor fetal growth and anatomy and referral to a maternal-fetal medicine or infectious disease specialist with expertise in pregnancy management is recommended. (cdc.gov)
  • Maternal-fetal transmission of Zika virus has been documented throughout pregnancy ( 4 , 7 , 8 ). (cdc.gov)
  • link cigarette smoke to fetal health and Questions on pregnancy and smoking were administered as part of this supplement include an association between nicotine to women 18-44 years of age who either had a live birth in the 5 years preceding and decreased placental blood flow and the interview, or who were pregnant at the time of the interview. (cdc.gov)
  • Women who smoked after learning of their smoking behavior, including the pregnancy were most likely to be light smokers, representing a shift in smoking gestational timing of smoking cessation behaviors after learning of pregnancy. (cdc.gov)
  • Because cyclooxygenase-2 (COX-2) dependent prostaglandin synthesis is implicated in preterm birth, we evaluated effects of mono-2-ethylhexyl phthalate (MEHP), the active metabolite of DEHP, on prostaglandin E2 (PGE2) synthesis and COX expression in human placental macrophages (PM). In addition, responses in PM were compared to those in a human macrophage-like cell line, THP-1. (biomedcentral.com)
  • A better understanding of contributing factors and mechanisms controlling untimely labor is necessary to prevent preterm birth and to improve maternal and fetal health. (biomedcentral.com)
  • Despite the mounting epidemiological evidence demonstrating an association between maternal DEHP exposure and increased risk for preterm birth, the mechanisms underlying these relationships are unclear. (biomedcentral.com)
  • We did not observe any associations between maternal cortisol levels and preterm birth and low birth weight. (researchsquare.com)
  • Common adverse birth outcomes, including preterm birth, low birth weight, and small-for-gestational age (SGA), are associated with neonatal mortality and long-term health problems, including neurodevelopmental impairments, respiratory and gastrointestinal complications, and higher sympathetic activity, which is considered a risk factor for cardiovascular disease [1-4]. (researchsquare.com)
  • The aim of this systematic review is to explore the association between placental histopathological abnormality and preterm birth in the presence of confirmed infection. (ox.ac.uk)
  • PubMed/Medline, Scopus, Web of Science and Embase were searched using the keywords related to preterm birth, placental histopathology and infection. (ox.ac.uk)
  • Studies on preterm birth needs to occur in high burden countries and control for clinical characteristics (maternal, fetal, labor, and placental) that may have an impact on placental histopathological abnormalities. (ox.ac.uk)
  • Serious maternal complications, perinatal death, small-for-gestational-age infants, preterm birth, and neonatal intensive care unit (NICU) admission were the primary outcomes of the analysis. (drugtopics.com)
  • Results Pregnant women involved in MVCs had significantly higher risks of placental abruption (aOR=1.51, 95% CI 1.30 to 1.74), prolonged uterine contractions (aOR=1.31, 95% CI 1.11 to 1.53), antepartum haemorrhage (aOR=1.19, 95% CI 1.12 to 1.26) and caesarean delivery (aOR=1.05, 95% CI 1.02 to 1.09) than the controls. (ncku.edu.tw)
  • Fetal growth restriction, stillbirth, and placental abruption. (blogspot.com)
  • Placental lesions were classified as consistent with maternal circulation abnormalities or fetal thrombo-occlusive disease or inflammatory responses of maternal (MIR) or fetal (FIR) origin. (tau.ac.il)
  • They found, however, that the sensitivity of first-trimester uterine artery Doppler is greater for SGA with preeclampsia than it is for IUGR alone and noted that this difference could be the result of different underlying placental abnormalities that are detected variably on first-trimester uterine artery Doppler evaluation. (medscape.com)
  • The Association between Placenta Accreta Spectrum Severity and Incidence of Small for Gestational Age Neonates. (bvsalud.org)
  • The aim of the study is to evaluate whether pathologic severity of placenta accreta spectrum (PAS) is correlated with the incidence of small for gestational age (SGA) and neonatal birthweight . (bvsalud.org)
  • Anterior placentation was the commonest, followed by posterior, then fundal with placenta previa being the least site of placental localization. (bvsalud.org)
  • Evaluation for placental localization in the second and third trimesters is important to rule out placenta previa. (bvsalud.org)
  • Maternal spiral arteries undergo extensive remodeling during a key window of 6 to 20 weeks' gestation allowing for appropriate perfusion of the placenta [ 7 ]. (biomedcentral.com)
  • Accumulating evidence suggests that pre-eclampsia is the product of abnormal spiral artery development leading to placental hypoxia, triggering the release of fetal-derived molecules that increase maternal blood pressure and perfusion of the placenta but result in diffuse endothelial dysfunction in the mother [ 4 ]. (biomedcentral.com)
  • Since the VDR and 1a-hydroxylase are expressed in reproductive tissues including ovary, uterus, placenta, testis and hypophysis an association with vitamin D and many potential pathways linking vitamin D to reproductive health outcomes almost suggests itself [19-21]. (vitamindwiki.com)
  • Fetal ovarian cysts have been associated with pregnancies complicated by maternal diabetes, toxemia, and Rh isoimmunization, probably due to the increased production of hCG by the placenta and are rarely associated with other congenital anomalies [2, 4, 6, 12-14]. (degruyter.com)
  • hCG, produced in the placenta, partially passes the placental barrier. (medscape.com)
  • Journal of perinatology : official journal of the California Perinatal Association. (ufl.edu)
  • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. (ufl.edu)
  • Untreated gestational diabetes leads to increased maternal and perinatal morbidity. (diabetes.ca)
  • At this time, doctor will find out if women are at increased risk of gestational diabetes. (healthhyme.com)
  • These effects may partly be related to the heightened risk of gestational diabetes, occurring in at least 16% of all pregnancies irrespective of current body weight. (karger.com)
  • Pregnant patients are routinely screened for gestational diabetes mellitus between 24 and 29 weeks' gestation. (healthhyme.com)
  • Using mixed effects regression models to control for BP measurement conditions, maternal and child characteristics, we examined the association between the F/E ratio and child BP. (umass.edu)
  • Multivariable regression analysis was used to determine whether maternal characteristics, ultrasound, and placental biomarkers affect FF and test accuracy. (nih.gov)
  • Objectives: To investigate the association between clinical characteristics and placental histopathology in women with intrapartum fever (IPF) at term. (tau.ac.il)
  • Methods: Maternal characteristics, intrapartum parameters, neonatal outcome and placental pathology were compared between 120 patients with IPF (≥380C) and a control group matched for mode of delivery. (tau.ac.il)
  • Information on the impact of maternal, gestational or neonatal characteristics on milk macronutrient composition could help identify mother-infant pairs at higher risk of extrauterine growth restriction and move towards a more individualized nutritional support [ 24 ]. (nature.com)
  • In this context, we aimed to measure macronutrient content of very preterm milk and to identify changes associated with time and maternal, gestational and neonatal characteristics. (nature.com)
  • Selected demographic characteristics spontaneous abortion, and infant death of women--including age, race, education, and family income--are also presented. (cdc.gov)
  • The objective of this study was to examine factors that influence the concentration of immunoglobulin G (IgG) in cord serum and the placental transfer of total IgG and of IgGs against Klebsiella spp. (usp.br)
  • Newborn serum beta hCG concentrations are approximately 1/400th of the corresponding maternal serum concentrations, resulting in neonate beta hCG levels of 10-50 IU/L at birth. (medscape.com)
  • Uterine enlargement as seen in an ultrasound can be a presenting sign of gestational choriocarcinoma. (wikipedia.org)
  • Ultrasound scans were performed every 5±1 weeks until delivery to measure fetal growth and feto-placental blood flow, and we used finite mixture models to derive growth trajectories of abdominal circumference. (warwick.ac.uk)
  • We identified four ultrasound-derived trajectories of fetal abdominal circumference growth that accelerated or decelerated within a crucial 20-25 week gestational age window: faltering growth, early accelerating growth, late accelerating growth, and median growth tracking. (warwick.ac.uk)
  • The most common definition of Intrauterine Growth Restrictio n (IUGR) is a fetal weight that is below the 10th percentile for gestational age as determined through an ultrasound . (americanpregnancy.org)
  • Gestational age can be calculated by using the first day of your last menstrual period (LMP) and also by early ultrasound calculations. (americanpregnancy.org)
  • Journal of Maternal-Fetal and Neonatal Medicine , 25 (8), 1273-1277. (tau.ac.il)
  • In a cohort study using propensity score-matching at the level of age, body mass index (BMI), and underlying conditions (e.g., diabetes, hypertension, asthma), Badr et al. (cdc.gov)
  • Animal data show that decreased activity of placental 11-beta-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which potently inactivates glucocorticoids (e.g. cortisol) to inert forms (cortisone), allows increased access of maternal glucocorticoids to the fetus and 'programs' hypertension. (umass.edu)
  • Placental insufficiency associated with hypertension accounted for most stillbirths. (plos.org)
  • Placental findings consistent with chronic hypertension were common among HIV-infected women who received HAART and among HIV-uninfected women (65% vs. 54%, p = 0.37), but less common among HIV-infected women not receiving HAART (28%, p = 0.003 vs. women on HAART). (plos.org)
  • Hypertension and placental insufficiency were associated with most stillbirths in this tertiary care setting. (plos.org)
  • Falciparum malaria was associated with gestational hypertension amongst multigravidae (adjusted odds ratio (AOR) 2.59, 95%CI 1.59-4.23), whereas amongst primigravidae, it was associated with the combined outcome of pre-eclampsia/eclampsia (AOR 2.61, 95%CI 1.01-6.79). (biomedcentral.com)
  • The clinical presentation ranges from gestational hypertension to pre-eclampsia to life-threatening eclampsia [ 1 ]. (biomedcentral.com)
  • It is unclear whether gestational hypertension and pre-eclampsia are separate entities or represent a spectrum of disease as they share some but not all risk factors and result in varying placental pathology, with findings consistent with placental ischemia specifically associated with pre-eclampsia [ 5 ]. (biomedcentral.com)
  • Chronic hypertension (HTN) is determined by this threshold being met before 20 weeks of gestation, while HTN is gestational when met at 20 weeks or more of gestation. (drugtopics.com)
  • Gestational hypertension is high blood pressure that you develop while you are pregnant. (medlineplus.gov)
  • Some women with gestational hypertension do go on to develop preeclampsia. (medlineplus.gov)
  • Patients who develop gestational diabetes may develop diabetes later in life. (healthhyme.com)
  • Association of intrauterine growth restriction and small for gestational age status with childhood cognitive outcomes: a systematic review and meta-analysis. (jamanetwork.com)
  • Intrauterine Growth Restriction is also known as Small-for-Gestational-Age (SGA) or fetal growth restriction. (americanpregnancy.org)
  • Melchiorre et al found that there is a significant relationship between first-trimester uterine artery Doppler resistance indices (RI) and the subsequent delivery of neonates who are small for gestational age (SGA) or have intrauterine growth restriction. (medscape.com)
  • A peripheral maternal blood smear was ni infants considered by their mothers to be made by finger prick. (who.int)
  • The risk of childhood obesity is increased among infants who had overweight or obesity at birth, but in low-resource settings one in five infants are born small for gestational age. (warwick.ac.uk)
  • The infants' health, growth, and development were monitored from birth to age 2 years. (warwick.ac.uk)
  • From Feb 8, 2012, to Nov 30, 2019, we enrolled 3598 pregnant women and followed up their infants to 2 years of age. (warwick.ac.uk)
  • In premature infants, gestational age was negatively correlated with school-age systolic blood pressure [ 12 , 13 ]. (scientificarchives.com)
  • In other words, preterm infants were smaller but had higher systolic blood pressure at school age. (scientificarchives.com)
  • In 1991, concerns about the relative safety of these procedures arose after reports were published that described a possible association between CVS and birth defects in infants. (cdc.gov)
  • In the United States, the current standard of care in obstetrical practice is to offer either CVS or amniocentesis to women who will be greater than or equal to 35 years of age when they give birth, because these women are at increased risk for giving birth to infants with Down syndrome and certain other types of aneuploidy. (cdc.gov)
  • Maternal and fetal risk factors for stillbirth: population based study. (jamanetwork.com)
  • Few studies have performed pathologic placental examinations among HIV-infected women [10] - [15] , and none to our knowledge have focused specifically on stillbirth, or the relationship between HAART and stillbirth. (plos.org)
  • The association between stillbirth and hereditary thrombophilia is not clear but does not appear to be strong, except for possibly factor V Leiden mutation. (msdmanuals.com)
  • [ 1 ] Maternal morbidity and mortality are also increased in pregnancies complicated by multiple gestations and multiple births. (medscape.com)
  • Multiple-gestation pregnancies are associated with a significantly higher maternal complication rate than are singleton gestations. (medscape.com)
  • Cortisol could also affect birth weight by stimulating the production and release of placental corticotrophin releasing hormone (CRH), leading to shortened gestation [18]. (researchsquare.com)
  • Body mass index (BMI), gestation, and placental biomarkers were found to be significant factors associated with FF. (nih.gov)
  • Eligibility criteria included having BP measurements from 20 weeks or more of gestation and evaluating the association between BP measurements and maternal or neonatal outcomes. (drugtopics.com)
  • Gestational weight gain (GWG) reflects different changes arising from gestation, including accumulation of body fat in women, liquid expansion, fetal and placental development, growth in breast tissue and the uterus. (scielosp.org)
  • The transcerebellar diameter in millimeters is equal to gestational age in weeks to 22 weeks of gestation. (medscape.com)
  • The syncytiotrophoblast produces regular hCG, which promotes progesterone production by the corpus luteum until placental progesterone production becomes established (after 6 weeks of gestation). (medscape.com)
  • Of 1529 articles, only 23 studies (13 bacterial, 6 viral and 4 parasitic) were included, and they used 7 different gestational age windows, and 20 different histopathological classification systems, precluding data pooling. (ox.ac.uk)
  • Studies span different gestational ages, analyze single or pooled samples and use a variety of techniques to determine macronutrient content. (nature.com)
  • Association between umbilical cord glucocorticoids and blood pressure " by Susanna Y. Huh, Ruth Andrew et al. (umass.edu)
  • We examined in humans the association between venous umbilical cord blood glucocorticoids, a potential marker for placental 11β-HSD2 enzyme activity, and blood pressure at age 3 years. (umass.edu)
  • A higher F/E ratio in umbilical venous cord blood, likely reflecting reduced placental 11β-HSD2 activity, was associated with higher systolic blood pressure at age 3 years. (umass.edu)
  • The most frequently studied vessel in Doppler velocimetry is the umbilical artery because of its accessibility and association with fetal outcome. (medscape.com)
  • If the estimated fetal weight is below the 10th percentile for gestational age, they suggest that further evaluation be considered, such as amniotic fluid assessment and Doppler blood flow studies of the umbilical artery. (medscape.com)
  • Recognize maternal and fetal complications of AT deficiency. (blogspot.com)
  • There is a lack of data in the literature regarding the placental transport of immunoglobulins in twin pregnancies. (usp.br)
  • Depending on the risk of gestational trophoblastic disease (GTD) development, such as in certain people with mole pregnancies, chemotherapy has been used in a preventative manner in the past. (wikipedia.org)
  • The incidence of multiple zygotic pregnancies varies in relation to maternal age, the use of assisted reproductive technology (ART), and ethnicity. (medscape.com)
  • Ie, the neonatal mortality rate in multiple-fetus pregnancies is similar to singleton rates, increasing with decreasing gestational age. (medscape.com)
  • According to the American Diabetes Association (2013), gestational diabetes affects 18% of pregnancies. (healthhyme.com)
  • Most women with gestational diabetes go on to have normal pregnancies with healthy babies. (healthhyme.com)
  • Women with gestational diabetes should be encouraged to breastfeed immediately after birth and for a minimum of 4 months to prevent neonatal hypoglycemia, childhood obesity, and diabetes for both the mother and child. (diabetes.ca)
  • Data including maternal history , neonatal birthweight , and placental pathology were collected and deidentified. (bvsalud.org)
  • and placental pathology (blinded to HIV and treatment status) were performed. (plos.org)
  • The secondary outcomes included incidence of large for gestational age (LGA) babies as defined by birth weight greater than the 90th percentile as well as incidence of SGA and LGA in preterm and term gestations. (bvsalud.org)
  • A Mediterranean diet with additional extra virgin olive oil and pistachios reduces the incidence of gestational diabetes mellitus (GDM): a randomized controlled trial: the St. Carlos GDM Prevention Study. (jamanetwork.com)
  • Sherer, DM , Spong, CY & Salafia, CM 1997, ' Residual amniotic fluid volume in preterm rupture of membranes: Association with fetal presentation and incidence of clinical and histologic evidence of infection ', American Journal of Perinatology , vol. 14, no. 3, pp. 125-128. (elsevierpure.com)
  • We conducted an international multicenter retrospective cohort study, PregOuTCOV, to examine the effect of gestational age at time of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on obstetric and neonatal outcomes. (cdc.gov)
  • Some reports have demonstrated that rates of preterm and cesarean delivery have increased ( 6 - 10 ), whereas others have reported a close association between SARS-CoV-2 infection and preeclampsia or preeclampsia-like syndromes ( 11 ). (cdc.gov)
  • Studies are under way to investigate the association of Zika virus infection and microcephaly, including the role of other contributory factors (e.g., prior or concurrent infection with other organisms, nutrition, and environment). (cdc.gov)
  • Pathophysiology of placental-derived fetal growth restriction. (jamanetwork.com)
  • Although the underlying pathophysiology of dystocia remains unclear, a high maternal BMI has been associated with a higher frequency of a prolonged first stage of labor [ 8 , 9 ]. (biomedcentral.com)
  • 3. Maternal-Newborn Nursing: A Family-Centered Approach Fifth Ed. Olds, Sally B., et al, 1996. (americanpregnancy.org)
  • To assess COVID-19 association with newborn critical care outcomes, including nursery level of care and ventilation, during three time periods: Pre-delta (May 2020-June 2021), Delta (July-November 2021), and Omicron (December 2021-February 2022). (chop.edu)
  • To the best of our knowledge, this is the first study investigating the association between prenatal PM 2.5 exposure and newborn DNA methylation of the IGF2/H19 . (biomedcentral.com)
  • Cord blood DNA methylation status of IGF2/H19 cluster was measured in 189 mother-newborn pairs from the ENVIR ON AGE birth cohort (Flanders, Belgium). (biomedcentral.com)
  • From the ongoing population-based prospective ENVIRONmental influence ON AGEing in early life (ENVIR ON AGE) birth cohort [ 23 ], 199 mother-newborn (all singleton) pairs that were recruited between July 2014 and June 2015 were included. (biomedcentral.com)
  • These findings could inform personalized preconception care for women to optimize maternal and neonatal health. (biomedcentral.com)
  • Prior Mendelian randomization (MR) studies exploring this question do not distinguish the mechanistic contributions of variants that directly influence birth weight through the foetal genome (direct foetal effects), vs. variants influencing birth weight indirectly by causing an adverse intrauterine environment (indirect maternal effects). (imperial.ac.uk)
  • Assisted reproductive technology (ART) has been widely used in the treatment of infertility, and is associated with adverse maternal and neonatal outcomes. (biomedcentral.com)
  • Logistic regression models were utilized to investigate the association between ART, PIH, and adverse neonatal outcomes, expressed as odds ratio (OR) and 95% confidence interval (CI). (biomedcentral.com)
  • The distribution-of-the-product was 0.31 (95%CI: 0.28-0.34), and 8.51% of the association between ART and adverse neonatal outcomes was mediated through PIH. (biomedcentral.com)
  • Among different adverse neonatal outcomes, PIH mediated 29.17% of the association between ART and low birth weight, 9.37% of the association between ART and premature birth, and 12.20% of the association between ART and NICU admission. (biomedcentral.com)
  • This study supports a mediating role for PIH in the association between ART and adverse neonatal outcomes. (biomedcentral.com)
  • Ambient airborne fine particulate matter with diameter smaller than 2.5 μm, PM 2.5 , is one of the air pollution components with the strongest adverse effects on health and mortality as it can penetrate the respiratory system, circulate via bloodstream to other organs [ 9 , 10 ] and cross the maternal-fetal placental barrier [ 11 , 12 ]. (biomedcentral.com)
  • Scooter riders had higher ORs of various adverse maternal outcomes than car drivers. (ncku.edu.tw)
  • Several PAH metabolites [1-hydroxyphenanthrene (1-OH-Phe), Σ2-,3-hydroxyphenanthrene (Σ2-,3-OH-Phe), 4-hydroxyphenanthrene (4-OH-Phe), 1-hydroxypyrene (1-OH-Pyr), Σ2-,3-hydroxyfluorene (Σ2-,3-OH-Flu)] were quantified in spot urine collected around gestational week 8 using LC-MS/MS. Child weight and height were measured at 19 occasions from birth to. (lu.se)
  • Multivariable-adjusted regression models were used to assess associations of maternal PAH metabolites (log 2-transformed) with child anthropometry. (lu.se)
  • Maternal urinary PAH metabolites were not associated with child anthropometry at 10 years. (lu.se)
  • 31 maternal metabolites had a negative effect for the faltering growth phenotype and 76 for the early accelerating growth phenotype. (warwick.ac.uk)
  • Determination of placental chorionicity can be evaluated by obstetric ultrasonography during the first and early second trimester. (medscape.com)
  • Maternal genotype for the Gln223Arg leptin receptor gene polymorphism showed no significant association with foetal birth weight (adjusted for gestational length) or with maternal BMI during first trimester (adjusted for age) in either population group. (ox.ac.uk)
  • Previously, gestational age was confirmed by sonography in the first trimester. (degruyter.com)
  • Among 286 newborns in Project Viva, a prospective pre-birth cohort study based in eastern Massachusetts, we measured cortisol ( F ) and cortisone ( E ) in venous cord blood and used the ratio of F/E as a marker for placental 11β-HSD2 activity. (umass.edu)
  • The F/E ratio was not associated with diastolic blood pressure or birth weight for gestational age z -score. (umass.edu)
  • A health statistics review uses existing health data from data sources like birth certificates and health registries to determine whether health outcomes in a particular community are occurring at a higher, lower, or about the same level compared to statewide or national levels after taking into account factors such as gender and age of individuals within the community. (cdc.gov)
  • For each study group, vertical box plot represents birth weight and horizontal box plot, gestational age at delivery. (jamanetwork.com)
  • 5 × 10−8) single nucleotide polymorphisms were extracted from genome-wide association studies summary statistics for birth weight overall, and after isolating direct foetal effects only. (imperial.ac.uk)
  • Previous research linked maternal psychosocial problems with increased risks of these birth outcomes, but the underlying mechanisms have not been fully understood yet [5]. (researchsquare.com)
  • Several biological mechanisms have been proposed for linking elevated maternal cortisol levels to infant birth weight. (researchsquare.com)
  • The results of previous studies on the associations between elevated maternal cortisol, fetal growth, and gestational age at birth were inconsistent [7, 20-23]. (researchsquare.com)
  • We aimed to elucidate the impact of early gestational PAH exposure on anthropometry from birth to 10 years of age in 1295 mother-child pairs from a nested sub-cohort of the MINIMat trial in Bangladesh. (lu.se)
  • OBJECTIVE: This study investigates the influence of the leptin receptor gene variant Gln223Arg (A→G, 668), on maternal body mass index (BMI), foetal gestational length and birth weight in a cohort of 455 healthy pregnant women of Asian Indian (India, Bangladesh, Pakistan) and UK/Irish origin. (ox.ac.uk)
  • Liang J, Gu1 A. Commentary on Association between Birth Weight and Risk of Cardiovascular Disease: Evidence from UK Biobank. (scientificarchives.com)
  • In our study, the association between birth weight and adult CVD was observed by Cox regression using recall of birth weight data from a large UKB cohort [ 5 ]. (scientificarchives.com)
  • Our study focused on the association between birth weight and the risk of CVD, but reckoned without the effect of other prenatal factors on CVD, such as premature birth and intrauterine malnutrition, because of the lack of prenatal factors in UK Biobank. (scientificarchives.com)
  • Cross-sectional data were collected from 369 mother-infant dyads at delivery on mother height (MH), mother haemoglobin (mHb), child haemoglobin (cHb), mid-upper arm circumference (MUAC), gestational age (GA), placental weight (PW), birth weight (BW), crown-heal length (CHL), and head circumference (HC). (who.int)
  • Results-- Of 13,674,000 women with a recent live birth, about 39 percent had consistent association with maternal ever smoked, 25 percent smoked in the year before they became pregnant, and smoking (1,5). (cdc.gov)
  • The latter may also be affected by the bi-directional association between inflammation and cortisol [19]. (researchsquare.com)
  • Placental TLR/NLR expression signatures are altered with gestational age and inflammation. (ufl.edu)
  • and hospitalization), and placental histologic parameters of maternal and/or fetal acute inflammation. (elsevierpure.com)
  • Maternal age was of the United States from which national and considerably reduce the risk of low also found to be associated with estimates of household and individual birthweight (4). (cdc.gov)
  • Four in five neonatal deaths of preterm births occur in low and middle income countries and placental histopathology examination can help clarify the pathogenesis. (ox.ac.uk)
  • Only 17 women had malaria ( Plasmodium falciparum ), 6 with peripheral parasitaemia and 11 with both peripheral parasitaemia and placental malaria. (who.int)
  • The purpose of the study is to determine and provide information on the commonest sites of placental localization in pregnant women in their second and third trimesters in Umuahia, Abia state because there are few documented reports on the sonographic assessment of placental localization in Umuahia. (bvsalud.org)
  • One hundred women between the ages of 20yrs and 42yrs with a mean age of 28.60±4.95 on their routine antenatal visit were used for the study. (bvsalud.org)
  • However, recent evidence demonstrates that the prevalence of vitamin D deficiency in women of childbearing age is surprisingly high [9-12]. (vitamindwiki.com)
  • We randomly selected 83 274 control births from women in the BN matched on age, gestational age and crash date. (ncku.edu.tw)
  • The objective of our study is to present the maternal and neonatal outcomes of COVID-19 positive pregnant women, who were admitted to our tertiary maternity hospital since the beginning of the pandemic in Greece. (degruyter.com)
  • The FL/AC Ratio for Prediction of Shoulder Dystocia in Women with Gestational Diabetes. (utswmed.org)
  • Gestational weight gain across c4ontinents and ethnicity: systematic review and meta-analysis of maternal and infant outcomes in more than one million women. (scielosp.org)
  • 20 weeks) with an A1C should be done to identify women with potentially overt diabetes to guide fetal surveillance and early maternal treatment, including self-monitoring of blood glucose, interventions that promote healthy behaviours and healthy weight gain. (diabetes.ca)
  • Dystocia is a common obstetric complication among nulliparous women, which requires medical intervention and carries the risk of negative maternal and neonatal outcomes. (biomedcentral.com)
  • Women with multiple pregnan- important predictors of fetal survival environmental factors ( 16 - 18 ), but cies, gestational diabetes, and those and health. (who.int)
  • Multivariable linear and logistic regression was performed to assess the associations between continuous and categorized cortisol levels and the selected outcomes. (researchsquare.com)
  • Association between independent and dependent variables was analyzed using binary logistic regression model. (bvsalud.org)
  • IPF at term is independently associated with placental inflammatory lesions. (tau.ac.il)
  • We investigated the association between cord blood DNA methylation status of the IGF2/H19 gene cluster and maternal fine particulate matter exposure during fetal life. (biomedcentral.com)
  • Polycyclic aromatic hydrocarbons (PAHs) have endocrine disrupting properties and they cross the placental barrier, but studies on gestational exposure and child anthropometry are inconclusive. (lu.se)
  • To determine if the definition of gestational HTN should be updated based on these guidelines, investigators conducted a systematic review. (drugtopics.com)
  • Association of gestational weight gain with maternal and infant outcomes: a systematic review and meta-analysis. (scielosp.org)
  • A quality improvement initiative to reduce the time to initial maternal visit in the neonatal intensive care unit. (ufl.edu)
  • Our data suggest that increased fetal exposure to active maternal glucocorticoids may program later systolic blood pressure. (umass.edu)
  • In conclusion, gestational PAH exposure was positively associated with fetal and early childhood growth, especially in boys. (lu.se)
  • Prenatal PM 2.5 exposure was found to have genetic region-specific significant association with IGF2 and H19 during specific gestational weeks. (biomedcentral.com)
  • Alterations in methylation of the imprinted IGF2/H19 cluster might be a potential mechanism underlying the association between in utero PM 2.5 exposure and fetal growth, as maternal residential PM 2.5 has been reported to alter their expression [ 22 ]. (biomedcentral.com)
  • One of the hypothesized intermediaries for this association is maternal cortisol, a glucocorticoid [6-8]. (researchsquare.com)