Pituitary gonadotropin releasing hormone. Medical search. Frequent questions

These drugs act as potent inhibitors of gonadotropin secretion by binding competitively on GnRH receptors. (medscape.com)
Gonadotropin-releasing hormone (GnRH) agonists, currently used in the treatment of advanced prostate cancer, have been described as a rare cause of pituitary apoplexy, a potentially life-threatening clinical condition. (unboundmedicine.com)
We report the case of a 69-year-old man with a known pituitary macroadenoma who was diagnosed with prostate cancer and started treatment with GnRH agonist leuprorelin (other hormones were not tested before treatment). (unboundmedicine.com)
This case describes a rare phenomenon, pituitary apoplexy induced by GnRH agonist. (unboundmedicine.com)
Gonadotropin-releasing hormone (GnRH) is secreted from the hypothalamus by GnRH-expressing neurons. (wikipedia.org)
GnRH travels down the anterior portion of the pituitary via the hypophyseal portal system and binds to receptors on the secretory cells of the adenohypophysis. (wikipedia.org)
Inhibin acts to inhibit activin, which is a peripherally produced hormone that positively stimulates GnRH-producing cells. (wikipedia.org)
In addition, leptin and insulin have stimulatory effects and ghrelin has inhibitory effects on gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus. (wikipedia.org)
citation needed] In males, the production of GnRH, LH, and FSH are similar, but the effects of these hormones are different. (wikipedia.org)
REPRODUCTIVE TOXICOLOGY: Impact of endocrine disruptors on neurons expressing GnRH or kisspeptin and pituitary gonadotropins. (nih.gov)
Reproduction is a complex process that is controlled centrally via a network of hypothalamic neurons to modulate the pulsatile release of gonadotropin-releasing hormone (GnRH) and subsequently pituitary gonadotropins. (nih.gov)
Due to the expression of these receptors, GnRH neurons, the hypothalamic neurons that control them, and pituitary gonadotropes are sensitive to exogenous compounds that interact with steroid and nuclear receptors or alter hormone production and metabolism. (nih.gov)
The purpose of this review is to evaluate these studies primarily focusing on GnRH and kisspeptin neurons and anterior pituitary gonadotropins and to discuss the need for deeper investigations into the hypothalamic-pituitary-gonadal axis. (nih.gov)
Gonadotropin releasing hormone (GnRH) from the hypothalamus stimulates the release of LH. (missouri.edu)
What is the effect of gonadotropin-releasing hormone (GnRH)-agonist treatment on serum anti-Müllerian hormone (AMH)? (frontiersin.org)
Similarly, the use of gonadotropin-releasing hormone (GnRH) agonist downregulation in women of reproductive age has demonstrated that AMH levels are significantly affected ( 12 , 13 ). (frontiersin.org)
12. GnRH antagonist inhibition of gonadotropin and steroid secretion in boars in vivo and steroid production in vitro. (nih.gov)
17. Absence of a direct inhibitory effect of the gonadotropin-releasing hormone (GnRH) agonist D-Ser (TBU)6, des-Gly-NH2(10) GnRH ethylamide (Buserelin) on testicular steroidogenesis in men. (nih.gov)
Gonadotropin-stimulating hormone (GnRH) is made by the hypothalamus in the brain. (childrensnational.org)
LH response to GnRH is a blood test to help determine if your pituitary gland can correctly respond to gonadotropin releasing hormone (GnRH). (medlineplus.gov)
GnRH is a hormone made by the hypothalamus gland. (medlineplus.gov)
GnRH causes (stimulates) the pituitary gland to release LH. (medlineplus.gov)
The body produces gonadotropin-releasing hormone (GnRH) about every 2 hours. (nih.gov)
GnRH travels through the bloodstream to the pituitary gland, where it stimulates the gland to produce hormones called gonadotropins. (nih.gov)
Patients who have additional pituitary deficiencies, effectively ruling out isolated GnRH deficiency, whether these deficiencies are congenital or acquired (e.g. secondary to malignancy, infection, or irradiation). (nih.gov)
Hypothalamic GnRH is the primary regulator of reproduction in vertebrates, acting via the G protein-coupled GnRH receptor (GnRHR) in pituitary gonadotrophs to control synthesis and release of gonadotropins. (nih.gov)
To identify elements of the GnRHR-coupled gene network, GnRH was applied in a pulsatile manner for 6 hours to a mixed population of perifused pituitary cells from cycling females, mRNA was extracted, and RNA sequencing analysis was performed. (nih.gov)
In vitro, GnRH-induced expression of this gene is coupled with release of DMP1 in extracellular medium through the regulated secretory pathway. (nih.gov)
Pulsatile gonadotropin releasing hormone (GnRH) (25 ng/kg) was administered every 2 h for 7 d to assess pituitary responsiveness to exogenous GnRH. (jci.org)
MH did not exhibit a gonadotropin response to pulsatile GnRH. (jci.org)
On the other hand, the failure to respond to pulsatile GnRH is consistent with a pituitary defect in gonadotropin production. (jci.org)
The brain makes gonadotropin-releasing hormone (GnRH), which starts the changes toward sexual maturity. (akronchildrens.org)
GnRH signals the pituitary gland to release two puberty hormones into the bloodstream: LH and follicle stimulating hormone (FSH) . (akronchildrens.org)
Hypothalamic gonadotropin-releasing hormone (GnRH) neurons are key regulators of reproduction. (genome.jp)
They release GnRH into the portal circulation. (genome.jp)
In turn, GnRH stimulates the pituitary gland to secrete follicle-stimulating hormone and luteinizing hormone (LH) to regulate gonadal functions. (genome.jp)
Gonadal steroids provide feedback to regulate GnRH release. (genome.jp)
GnRH neurons express the kisspeptin receptor, GPR 54, and kisspeptins potently stimulate the release of GnRH by depolarising and inducing sustained action potential firing in GnRH neurons. (genome.jp)
Puberty starts when a part of your child's brain called the hypothalamus begins producing a hormone called gonadotropin-releasing hormone (GnRH). (clevelandclinic.org)
The hypothalamus sends GnRH to another part of the brain called the pituitary gland . (clevelandclinic.org)
For example, hypogonadism can occur in girls with Turner syndrome or in individuals with hypogonadotropic (pronounced HI-po-GO-nah-doe-TROH-pik ) hypogonadism, which occurs when the hypothalamus (pronounced HI-po-THAL-uh-muss ) produces little to no gonadotropin-releasing hormone (pronounced goh-nad-uh-TROH-pin ) (GnRH). (nih.gov)
For example, Kallmann syndrome affects the body's ability to produce gonadotropin-releasing hormone (GnRH) and can, in turn, impact sperm production. (healthline.com)
As in women, gonadotropin releasing hormone, or GnRH, is released in a pulsatile fashion, stimulating the release of follicle stimulating hormone (FSH) and leutinizing hormone (LH). (ucsfhealth.org)
Repeated reproductive cycles in women require the tight integration of signals from the hypothalamus (gonadotropin-releasing hormone [GnRH]) to the pituitary, resulting in secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH). (nih.gov)
DACT treatment also decreased release of LH from the pituitary in response to exogenous gonadotropin releasing hormone (GnRH) by 47% compared to control. (cdc.gov)
The hypothalamus in the brain releases GnRH. (nih.gov)
The hypothalamus secretes gonadotropin-releasing hormone (GnRH) which causes the anterior pituitary to produce luteinising hormone (LH) and follicle stimulating hormone (FSH). (bpac.org.nz)
More recently, endometriosis has been treated experimentally with analogs of the hypothalamic hormone, gonadotropin releasing factor (GnRH), which normally stimulates the pituitary gland to secrete the gonadotropin hormones that stimulate the ovary. (nih.gov)
Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. (drugbank.com)
Introduction: Hypothalamic gonadotropin releasing hormone (GnRH) regulates mammalian reproductive system. (endocrine-abstracts.org)
The hypothalamus releases a hormone called gonadotropin-releasing hormone (GnRH), which is an important hormone in both women and men. (thedoctorwillseeyounow.com)
Puberty occurs when a part of the brain called the hypothalamus releases Gonadotropin-Releasing Hormone (GnRH). (nuhs.edu.sg)
CPP occurs when the hypothalamus releases GnRH which activates puberty earlier. (nuhs.edu.sg)
A blood test (GnRH stimulation test) may be done to measure hormone levels and an X-ray of the hand may be obtained to see if the bones are maturing too fast. (nuhs.edu.sg)
Background: Precocious puberty (PP) in girls is most frequently an idiopathic gonadotropin-releasing hormone (GnRH)-dependent PP, being thelarche the typical first sign. (endocrine-abstracts.org)
EFFECT OF ESTRADIOL ON HYPOTHALAMIC GNRH AND PITUITARY AND SERUM LH AND FSH IN OVARIECTOMIZED PIGS. (ncsu.edu)
Two experiments were conducted to measure pituitary gonadotropins, hypothalamic-gonadotropin releasing hormone (GnRH) and pituitary response to GnRH during periods when serum luteinizing hormone (LH) was suppressed by estradiol-17 beta (e2) in ovariectomized pigs. (ncsu.edu)
The observation that E2 suppressed LH in serum without a detectable suppression of LH in AP led to the hypothesis that E2 had caused the suppression of serum LH by suppression of GnRH release. (ncsu.edu)
Thus the pituitary of the pig is capable of responding to GnRH when LH is normally suppressed by E2. (ncsu.edu)
Secretion of GnRH from the hypothalamus occurs in a pulsatile fashion and is partially responsible for controlling the number of GnRHRs in the pituitary gland and controls synthesis and secretion of FSH and LH. (endocrinology-journals.org)
Effects of GnRH activation of its receptor in stimulating diverse signaling pathways in the anterior pituitary. (endocrinology-journals.org)
Effects (means± s.e.m .) of GnRH-toxin or toxin alone on the ability of cultured anterior pituitary cells to synthesize LH (solid bars) or prolactin (shaded bars). (endocrinology-journals.org)
This article is about GnRH as a hormone. (wikidoc.org)
Gonadotropin-releasing hormone ( GnRH ) is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary . (wikidoc.org)
GnRH is a tropic peptide hormone synthesized and released from GnRH neurons within the hypothalamus . (wikidoc.org)
At the pituitary, GnRH stimulates the synthesis and secretion of the gonadotropins , follicle-stimulating hormone (FSH), and luteinizing hormone (LH). (wikidoc.org)
Low-frequency GnRH pulses are required for FSH release, whereas high-frequency GnRH pulses stimulate LH pulses in a one-to-one manner. (wikidoc.org)
GnRH is considered a neurohormone , a hormone produced in a specific neural cell and released at its neural terminal . (wikidoc.org)
FHA is caused when the hypothalamus stops producing gonadotropin-releasing hormone (GnRH). (mybinto.com)
The peptide's capacity to affect gonadotropin-releasing hormone (GnRH) interests scientists most. (4howtodo.com)
The hypothalamus is where gonadotropin-releasing hormone (GnRH) is produced and released. (4howtodo.com)
Male growth hormone, or GnRH, is an essential trigger for adolescent sexual development. (4howtodo.com)
Kisspeptin neurons' ability to stimulate GnRH release may be reduced by severe malnutrition and extreme overnutrition. (4howtodo.com)
The hypothalamus releases gonadotropin-releasing hormone (GnRH), which acts on your anterior pituitary gland. (healthnutrition.com)
Gonadotropin-releasing hormone (GnRH) is yet another pregnancy hormone made by the hardworking pituitary gland. (kopabirth.com)

The puberty is started by early secretion of hormones called gonadotropins. (childrensnational.org)
Instead it's caused by early secretion of high levels of sex hormones. (childrensnational.org)
Estrogen-progestin combinations of oral contraceptives reduce the secretion of LH and FSH from the pituitary by decreasing amount of gonadotropin-releasing hormones (GnRHs). (medscape.com)
These hormones are responsible for follicle growth within the ovary and secretion of estradiol and progesterone, inhibin A and inhibin B. In addition to its effect on reproduction, estrogen impacts cognition, mood, and vasomotor symptoms, additional areas of interest in the Hall lab. (nih.gov)
Total plasma LH secretion was reduced by 37% compared to control, suggesting that in addition to potential hypothalamic dysfunction, pituitary function is altered. (cdc.gov)
Insufficient growth hormone secretion. (nih.gov)
It binds receptors (GnRHRs) expressed in gonadotrope cells of anterior pituitary, regulating the synthesis and secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). (endocrine-abstracts.org)
SUPPRESSION OF LUTEINIZING-HORMONE AND TESTOSTERONE SECRETION IN BULLS FOLLOWING ADRENOCORTICOTROPIN HORMONE-TREATMENT. (ncsu.edu)

The anterior portion of the pituitary gland produces luteinizing hormone (LH) and follicle-stimulating hormone (FSH), and the gonads produce estrogen and testosterone. (wikipedia.org)
FSH stimulates sustentacular cells to release androgen-binding protein, which promotes testosterone binding. (wikipedia.org)
These conditions may include benign and malignant (cancerous) pituitary tumors, congenital adrenal hyperplasia, exposure to too much estrogen, exposure to too much testosterone, Cushing's syndrome, and chronic use of medications called glucocorticoids. (cdc.gov)
Testosterone Cypionate Injection, USP for intramuscular injection, contains Testosterone Cypionate, USP which is the oil-soluble 17 (beta)-cyclopentylpropionate ester of the androgenic hormone testosterone. (nih.gov)
During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH). (nih.gov)
Generally, the amount of this sex-hormone binding globulin in the plasma will determine the distribution of testosterone between free and bound forms, and the free testosterone concentration will determine its half-life. (nih.gov)
Male hypogonadism is a condition in which the body doesn't produce enough of the hormone that plays a key role in masculine growth and development during puberty (testosterone) or enough sperm or both. (drugs.com)
Male hypogonadism means the testicles don't produce enough of the male sex hormone testosterone. (drugs.com)
This type of hypogonadism indicates a problem in the hypothalamus or the pituitary gland - parts of the brain that signal the testicles to produce testosterone. (drugs.com)
Luteinizing hormone then signals the testes to produce testosterone. (drugs.com)
These men usually have low serum testosterone levels and gonadotropins (follicle-stimulating hormone [FSH], luteinizing hormone [LH]) above the normal range. (nih.gov)
These hormones travel to the sex organs (ovaries and testes), triggering them to begin releasing sex hormones (estrogen and testosterone). (clevelandclinic.org)
The rapid down-regulation of the pituitary-ovarian axis led to significant reduction of testosterone and androstenedione to 48.9% and 67.4% of baseline, respectively. (regrowth.com)
These hormones tell the female ovaries or the male testes to release hormones that lead to normal sexual development in puberty, normal menstrual cycles, estrogen levels and fertility in adult women, and normal testosterone production and sperm production in adult men. (nih.gov)
Testosterone production in males is regulated by the hypothalamic-pituitary-gonadal (HPG) axis. (bpac.org.nz)
The process is controlled by a negative feedback loop, with testosterone inhibiting the frequency and amplitude of hypothalamic and anterior pituitary secretions. (bpac.org.nz)
Significant increases in the volume of testosterone prescribed means a similar increase in laboratory testing of testosterone and other hormones. (bpac.org.nz)
When activated, the hormones increase estrogen in girls and testosterone in boys. (luriechildrens.org)
In both boys and girls, the adrenal glands make testosterone-like hormones that can be activated early. (luriechildrens.org)
This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. (drugbank.com)
Sex hormone replacement with testosterone or oestrogen may only be indicated in selected cases. (nuhs.edu.sg)
3]. Bouchard P, Lagoguey M, Brailly S, Schaison G. Gonadotropin-releasing hormone pulsatile administration restores luteinizing hormone pulsatility and normal testosterone levels in males with hyperprolactinemia. (iosrjournals.org)
Testosterone is the "male" sex hormone. (healthnutrition.com)
For the production of testosterone, three glands in the male body are required: the hypothalamus, the anterior pituitary gland, and the testes. (healthnutrition.com)
In response to the luteinizing hormone and follicle-stimulation hormone, your testes synthesize testosterone. (healthnutrition.com)
Acute consumption of alcohol has the ability to cause short-term impairment on testosterone release, by negatively affecting the hypothalamus and pituitary gland. (healthnutrition.com)
Heavy drinking of alcohol over a continued period can cause elevated levels of estrogen, the female sex hormone, testosterone converted to estrogen, and increased levels of the stress hormone cortisol, which can destroy testosterone. (healthnutrition.com)

These synthetic steroids probably work by a combination of depressed hypothalamic-pituitary response to lowered estrogen production, the alteration of sex steroid metabolism, and the interaction of the drug with sex hormone receptors. (medscape.com)
In females, the positive feedback loop between estrogen and luteinizing hormone help to prepare the follicle in the ovary and the uterus for ovulation and implantation. (wikipedia.org)
When the egg is released, the empty follicle sac begins to produce progesterone to inhibit the hypothalamus and the anterior pituitary thus stopping the estrogen-LH positive feedback loop. (wikipedia.org)
Cells making up the integrity of the follicle produce a hormone called estrogen. (missouri.edu)
Evidence that atrazine and diaminochlorotriazine inhibit the estrogen/progesterone induced surge of luteinizing hormone in female Sprague-Dawley rats without changing estrogen receptor action. (cdc.gov)
High oral doses of atrazine (ATRA) disrupt normal neuroendocrine function, resulting in suppression of the luteinizing hormone (LH) surge in adult, ovariectomized (OVX) estrogen-primed female rats. (cdc.gov)
In this study in vitro, we aim to evaluate whether the co-existing follicle-stimulating hormone receptor (FSHR) and G protein-coupled estrogen receptor (GPER) form heteromers, which may play role in selecting the dominant ovarian follicle. (endocrine-abstracts.org)
Many people have heard of the two major hormones involved in the female reproductive cycle: estrogen and progesterone. (thedoctorwillseeyounow.com)
It is the target of various regulatory mechanisms of the hypothalamic-pituitary-gonadal axis , such as being inhibited by increased estrogen levels in the body. (wikidoc.org)
Without this hormone, your ovaries stop producing estrogen and you stop ovulating, and thus menstruating. (mybinto.com)
Estrogen is the primary female sex hormone and one of the more well-known hormones of pregnancy. (kopabirth.com)

Pituitary apoplexy (PA) is a potentially life-threatening complication that can be caused by gonadotropin-releasing hormone agonist (GnRHa) administration for the treatment of advanced prostate cancer. (unboundmedicine.com)
TY - JOUR T1 - Pituitary apoplexy induced by gonadotropin-releasing hormone agonist administration: a rare complication of prostate cancer treatment. (unboundmedicine.com)
To describe a case and review the literature on the rare complication of pituitary apoplexy after administration of a gonadotropin-releasing hormone agonist (GnRHa) for treatment of patients with prostate cancer. (nih.gov)
2. Gonadotropin-releasing hormone and its agonist inhibit testicular luteinizing hormone receptor and steroidogenesis in immature and adult hypophysectomized rats. (nih.gov)
11. Lack of a direct effect of gonadotropin hormone-releasing hormone agonist on human testicular steroidogenesis. (nih.gov)

After puberty these hormones levels remain relatively constant. (wikipedia.org)
In girls, precocious puberty may be caused by the early maturity of the hypothalamus, pituitary glands and ovaries. (childrensnational.org)
This is a form of precocious puberty that is not started by the early release of gonadotropins. (childrensnational.org)
Normal puberty with subsequent development of low gonadotropin levels. (nih.gov)
Among patients with true precocious puberty, or full activation of the hypothalamic-pituitary-gonadal axis, most girls have an idiopathic etiology, whereas it is commonly due to identifiable pathology on imaging in boys. (aafp.org)
The physical changes of puberty are a result of gonadal sex hormone production, the start of which (gonadarche) indicates pubertal onset. (aafp.org)
LH ad FSH tell the testes and ovaries to make hormones that bring about changes during puberty. (akronchildrens.org)
Special hormones are produced and released that trigger the signs of puberty. (clevelandclinic.org)
These messenger hormones cause the telltale signs of puberty to begin. (clevelandclinic.org)
The right hormone treatment will cause puberty to start in children and may restore fertility in adults. (nih.gov)
The hypothalamus, pituitary, and gonads (ovaries in girls and testicles in boys) create a pathway for hormones activating the changes of puberty. (luriechildrens.org)
A naturally occurring human protein called kisspeptin (also known as metastin) is critical in hormone transmission throughout puberty and reproduction. (4howtodo.com)

The hypothalamic-pituitary exchange is controlled by gonadal steroids through negative and positive feedback mechanisms via steroid receptors. (nih.gov)
6. Effects of gonadotropin-releasing hormone receptor blockade on rat testicular gonadotropin and lactogen receptors, steroidogenesis, and responses to human chorionic gonadotropin stimulation. (nih.gov)
9. Anterior pituitary hormonal regulation of testicular gonadotropin-releasing hormone receptors. (nih.gov)
16. Receptors and inhibitory actions of gonadotropin-releasing hormone in the fetal Leydig cell. (nih.gov)
They act on postsynaptic dopamine receptors while causing no effect on other anterior pituitary functions. (medscape.com)
Steroid hormones are derived from cholesterol, produced by reproductive glands, are lipids, and bind to receptors within the cell. (proprofs.com)
Extracelluar membrane receptors are used by which of the following types of hormones? (proprofs.com)
Extracellular membrane receptors are used by catecholamines, peptide hormones, and eicosanoids. (proprofs.com)
These hormones are unable to pass through the cell membrane and therefore bind to receptors on the cell surface. (proprofs.com)
Thyroid hormones, on the other hand, are able to pass through the cell membrane and therefore use intracellular receptors to exert their effects. (proprofs.com)

Depresses the output of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). (medscape.com)
The gonadotropins, luteinizing hormone, and follicle-stimulating hormone, drive gametogenesis and hormone production from the gonads. (nih.gov)
Ovulation is initiated by a surge of luteinizing hormone (LH) from the pituitary gland. (missouri.edu)
13. Direct inhibitory effect of gonadotropin-releasing hormone upon luteal luteinizing hormone receptor and steroidogenesis in hypophysectomized rats. (nih.gov)
15. Direct inhibitory effect of glucocorticoids upon testicular luteinizing hormone receptor and steroidogenesis in vivo and in vitro. (nih.gov)
Gonadotropins include luteinizing hormone (LH) and follicle stimulation hormone (FSH). (childrensnational.org)
The hypothalamus produces gonadotropin-releasing hormone, which signals the pituitary gland to make follicle-stimulating hormone ( FSH ) and luteinizing hormone ( LH ). (drugs.com)
Baseline luteinizing hormone (LIT), follicle-stimulating hormone (FSH), and free-alpha-subunit (FAS) levels were determined during 24 h of frequent (q10 min) venous sampling. (jci.org)
What Is Luteinizing Hormone? (akronchildrens.org)
Luteinizing hormone (LH) is a hormone made by the pituitary gland. (akronchildrens.org)
In kids, luteinizing (LOO-tee-uh-nye-zing) hormone levels are high right after birth. (akronchildrens.org)
Pituitary luteinizing hormone (LH) and placental human choriogonadotropin (hCG) are two heterodimeric glycoprotein hormones regulating reproduction. (endocrine-abstracts.org)
Introduction: A primate-specific luteinizing hormone (LH) receptor (LHCGR)-variant was suspected to discriminate between maternal choriogonadotropin (hCG)- and fetal LH-functioning. (endocrine-abstracts.org)
Introduction: Luteinizing hormone (LH) and human choriogonadotropin (hCG) regulate reproduction through binding the same receptor (LHCGR). (endocrine-abstracts.org)
This hormone signals the pituitary gland to make and release two additional hormones that actually signal the sex organs to start working: in women, these are follicle stimulating hormone (FSH) and luteinizing hormone (LH). (thedoctorwillseeyounow.com)
and LH (Luteinizing Hormone), which stimulates the release of that egg (ovulation). (gynob.com)
It governs the production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary gland. (4howtodo.com)
Then, the anterior pituitary gland releases luteinizing hormone (LH) and follicle-stimulation hormone (FSH). (healthnutrition.com)
the Pituitary gland also makes luteinizing hormone (LH). (kopabirth.com)

The hypothalamic-pituitary-gonadal axis (HPG axis, also known as the hypothalamic-pituitary-ovarian/testicular axis) refers to the hypothalamus, pituitary gland, and gonadal glands as if these individual endocrine glands were a single entity. (wikipedia.org)
Fluctuations in this axis cause changes in the hormones produced by each gland and have various local and systemic effects on the body. (wikipedia.org)
In oviparous organisms (e.g. fish, reptiles, amphibians, birds), the HPG axis is commonly referred to as the hypothalamus-pituitary-gonadal-liver axis (HPGL-axis) in females. (wikipedia.org)
Previous studies have demonstrated that current or past use of oral contraceptives is associated with reduced serum AMH ( 9 , 10 ), with the effect being described as transient and potentially due to the altered development of antral follicles by downregulation of the hypothalamic-pituitary ovarian axis ( 10 , 11 ). (frontiersin.org)
18. Responsiveness of the pituitary-testicular axis to gonadotropin-releasing hormone and chorionic gonadotropin during the first week of life. (nih.gov)
Gonadarche is triggered by the pulsatile release of gonadotropin-releasing hormone, which activates the hypothalamic-pituitary-gonadal (HPG) axis. (aafp.org)
However, its relationship with signs of hypothalamic-pituitary-gonadal (HPG) axis activation and oestrogen exposure is still to be elucidated. (endocrine-abstracts.org)
Adrenarche, which typically begins between ages 6 and 9, refers to the maturation of the hypothalamic-pituitary-adrenal (HPA) axis, during which the levels of adrenal androgens (e.g., dehydroepiandrosterone and its sulfate) begin to increase. (nationalacademies.org)
Gonadarche typically begins in early adolescence, at approximately ages 9 to 11, and involves the reactivation of the hypothalamic-pituitary-gonadal (HPG) axis (for a review, see Sisk and Foster, 2004 ). (nationalacademies.org)
It constitutes the initial step in the hypothalamic-pituitary-gonadal axis . (wikidoc.org)
It is the first hormone secreted in the hypothalamic-pituitary-gonadal axis. (4howtodo.com)

With an understanding of the role of reproductive hormones, producers can modify their reproductive management programs to fit their needs. (missouri.edu)
Petersen PM, Skakkebaek NE, Vistisen K, Rørth M, Giwercman A. Semen quality and reproductive hormones before orchiectomy in men with testicular cancer. (medscape.com)
Association Between Use of Marijuana and Male Reproductive Hormones and Semen Quality: A Study Among 1,215 Healthy Young Men. (medscape.com)
Melatonin inhibits the release of pituitary reproductive hormones, known as gonadotropins, from the pituitary gland , affecting male and female reproductive organs. (mentalfloss.com)
High levels of cortisone cause the hypothalamus to stop releasing reproductive hormones. (mybinto.com)

These agents stimulate production of gonadal steroid hormones. (medscape.com)
These hormones stimulate the testicles or ovaries. (nih.gov)
HH is caused by a lack of hormones that normally stimulate the ovaries or testes. (nih.gov)
In adult patients, recent data showed that glucagon administration is able to stimulate the release of copeptin, the stable C-terminal glycopeptide of the AVP prohormone whose evaluation during hypertonic saline infusion represents the gold standard for the differential diagnosis of polyuria/polydipsia. (endocrine-abstracts.org)

At large doses of exogenous androgens, spermatogenesis may also be suppressed through feedback inhibition of pituitary follicle stimulating hormone (FSH). (nih.gov)

Follicle stimulating hormone (FSH) is produced by the anterior pituitary gland and it is a key hormone in the reproductive system. (endocrine-abstracts.org)

It may be caused by tumors or growths on the ovaries, adrenal glands, pituitary gland or brain. (childrensnational.org)

The hypothalamus and pituitary glands in the brain produce hormones that maintain normal testicular function. (cdc.gov)
1. Inhibitory effect of gonadotropin releasing hormone upon cultured testicular cells. (nih.gov)
4. Mechanism of the direct action of gonadotropin-releasing hormone and its antagonist on androgen biosynthesis by cultured rat testicular cells. (nih.gov)
5. Effect of injection of gonadotrophin-releasing hormone on testicular steroidogenesis in the hypogonadal (hpg) mouse. (nih.gov)
Pre-testicular azoospermia (non-obstructive) is caused by impaired production of the hormones responsible for creating sperm. (healthline.com)

Improper function of the hypothalamus or pituitary glands. (cdc.gov)
Hypogonadism is a condition in which the sex glands make little or no hormones. (medlineplus.gov)
Other children have a long-lasting condition known as hypogonadism (pronounced HI-poe-GO-nad-iz-uhm ) in which the sex glands (the testes in men and the ovaries in women) produce few or no hormones. (nih.gov)
The adrenal glands are separate from the hypothalamus-pituitary-gonad pathway. (luriechildrens.org)
It is one of the pregnancy hormones that helps in the stimulation of milk glands in the breasts, so that your body is ready to provide nutrition to baby after delivery. (kopabirth.com)

The test also can check for damage or disease of the testes or ovaries, pituitary gland, or hypothalamus, an area of the brain that links the nervous system with the hormone-making endocrine system . (akronchildrens.org)
Hypogonadotropic hypogonadism (HH) is a form of hypogonadism that is due to a problem with the pituitary gland or hypothalamus. (nih.gov)

This complication is rare but should be taken into account when using GnRHa, particularly in the setting of a known pre-existing pituitary adenoma. (unboundmedicine.com)
13. Gonadotropin releasing hormone analogue antiandrogen failure secondary to a pituitary adenoma. (nih.gov)

Treatment may be done with synthetic gonadotropin-releasing hormone agonists. (childrensnational.org)
4]. Lecomte P, Lecomte C, Lansac J, Gallier J, Sonier CB, Simonetta C. Pregnancy after intravenous pulsatile gonadotropin-releasing hormone in a hyperprolactinaemic women resistant to treatment with dopamine agonists. (iosrjournals.org)

Many women have heard of human chorionic gonadotropin (hCG) because it is the hormone that urine and blood pregnancy tests detect. (kopabirth.com)

These hormone levels also control the uterine (menstrual) cycle causing the proliferation phase in preparation for ovulation, the secretory phase after ovulation, and menstruation when conception does not occur. (wikipedia.org)
Injection of Cystorelin, Factre, Fertagyl or Ovacyst, causes the release of LH and results in ovulation or luteinization of a nonovulated follicle or cyst. (missouri.edu)
These hormones begin to rise prior to ovulation (the release of the egg from an ovary), and signal the body to begin preparing for ovulation and potential pregnancy. (thedoctorwillseeyounow.com)
LH is responsible for the mature follicle to be released from the ovary during ovulation. (thedoctorwillseeyounow.com)
Thus, a single hormone, GnRH1, controls a complex process of follicular growth, ovulation , and corpus luteum maintenance in the female, and spermatogenesis in the male. (wikidoc.org)

The gland translates nerve signals from the sympathetic nervous system into hormone signals. (mentalfloss.com)
Previous studies differentiated the action of these two hormones in LH-related proliferative signals and hCG-related steroidogenic signals.Aim. (endocrine-abstracts.org)

A separate analog of kisspeptin has been discovered to modify the pulse frequency of LH in males, indicating that kisspeptin helps fine-tune the regular pulsatile release of sex hormones. (4howtodo.com)
Kisspeptin-10 seems to accomplish this feat by boosting the pulsatile release of LH. (4howtodo.com)
Kisspeptin-10 may generate so fast pulsing that individual pulses are entirely obscured, resulting in continuous LH release at large dosages. (4howtodo.com)
So it is well established that kisspeptin synthesis and release are sensitive to energy balance. (4howtodo.com)

Ovarian Hyperstimulation Syndrome: If serious, stop gonadotropins, including hCG, and determine if the woman needs to be hospitalized. (nih.gov)
Introduction: The developmental stages of the ovarian follicle are characterized by changes of gonadotropin and steroid hormone receptor expression and their potential interactions on the surface of granulosa cells. (endocrine-abstracts.org)
To date, the best induction regimen is still to be established.Aims: By setting up a multicentre clinical registry, we analysed longitudinal data on pubertal induction in girls with hypogonadotropic hypogonadism or premature ovarian insufficiency (congenital, acquired, isolated or associated with multiple pituitary. (endocrine-abstracts.org)

Numerous studies have reported that perinatal, juvenile, or adult exposure to these EDCs, primarily in rats, disrupt the hypothalamic control of pituitary gonadotropin production leading to disruption of gonadal steroid production and estrous cyclicity. (nih.gov)
They are distinct from other types of hormones, such as steroid hormones, which are chemically related to cholesterol. (proprofs.com)
2 The rise of gonadal steroid hormones to adult levels occurs as a result of HPG reactivation and is primarily responsible for breast and genital development in girls. (nationalacademies.org)

C36285 Endocrine System Finding C118467 Pediatric Endocrine Terminology C112836 Thyroid Storm Thyroid Storm Acute onset of severe, life-threatening hyperthyroidism caused by a sudden release of excessive thyroid hormone. (nih.gov)

These two hormones play an important role in communicating to the gonads. (wikipedia.org)
The gonads (ovaries or testes) or adrenals create hormones earlier than usual. (luriechildrens.org)

19. The effects of a gonadotropin-releasing hormone antagonist on androgen-binding protein distribution and other parameters in the adult male rat. (nih.gov)

The hypothalamus is linked to the pituitary gland , which stores the hormones produced by the hypothalamus (which also produces other hormones, including the "love hormone" oxytocin) and regulates their release into the bloodstream. (mybinto.com)

C89330 Developmental Disorder C103185 Congenital Reproductive System Abnormality C118467 Pediatric Endocrine Terminology C110940 Panhypopituitarism Panhypopituitarism Complete Hypopituitarism Insufficient production of all the anterior pituitary hormones. (nih.gov)
C3009 Endocrine System Disorder C118467 Pediatric Endocrine Terminology C112834 Growth Hormone Excess Growth Hormone Excess Overproduction of growth hormone, a protein-based peptide that stimulates growth, cell reproduction, and cell regeneration. (nih.gov)
Though located in your brain, the pineal gland is actually a crucial part of your endocrine system , which regulates major bodily processes such as growth, metabolism, and sexual development through the release and control of hormones. (mentalfloss.com)
PULSATILE ADMINISTRATION OF GONADOTROPIN-RELEASING HORMONE TO LACTATING SOWS - ENDOCRINE CHANGES ASSOCIATED WITH INDUCTION OF FERTILE ESTRUS. (ncsu.edu)
Endocrine cells release their secretions directly into body fluids, such as blood or lymph, which allows the hormones they produce to be transported throughout the body. (proprofs.com)

Adrenal hypoplasia congenita with hypogonadotropic hypogonadism: evidence that DAX-1 mutations lead to combined hypothalmic and pituitary defects in gonadotropin production. (jci.org)
Hypogonadism is a condition in which the male testes or the female ovaries produce little or no sex hormones. (nih.gov)
Introduction: Follicle-stimulating hormone (FSH) biosimilars, differing for source cell and glycosylation pattern, are commercially available for therapy of hypogonadism and assisted reproduction techniques (ART). (endocrine-abstracts.org)

Introduction: Glucagon stimulation test is one of the recommended growth hormone provocation tests for diagnosing growth hormone deficiency in children. (endocrine-abstracts.org)

These then cause sex hormones to be made by the ovaries in girls, or the testes in boys. (childrensnational.org)

A deficiency of all anterior pituitary hormones, without necessary involvement of the hormones of the posterior pituitary gland (oxytocin and vasopressin). (nih.gov)

Production of too much prolactin, a hormone made by the pituitary gland (often due to the presence of a benign pituitary gland tumor), or other conditions that damage or impair the function of the hypothalamus or the pituitary gland may result in low or no sperm production. (cdc.gov)
Mimic dopamine action of inhibition of prolactin release. (medscape.com)

Peptide hormones are composed of amino acids, which are the building blocks of proteins. (proprofs.com)
These hormones are made up of chains of amino acids that are linked together by peptide bonds. (proprofs.com)
Peptide hormones play important roles in regulating various processes such as growth, metabolism, and reproduction. (proprofs.com)
The peptide belongs to gonadotropin-releasing hormone family . (wikidoc.org)

In the ECLIPSE trial, which compared the clinical effectiveness and cost-effectiveness of the levonorgestrel-releasing intrauterine system with standard medical care (ie, tranexamic acid, mefenamic acid, combined oestrogen-progestogen or progesterone alone) for menorrhagia, investigators noted that although both treatment groups had improved scores as measured by the Menorrhagia Multi-Attribute Scale (MMAS), significantly greater improvement occurred in the levonorgestrel intrauterine system group over a 2-year period. (medscape.com)
Progesterone is the hormone most commonly known for helping your body maintain, or keep a pregnancy, after conception. (kopabirth.com)

These gonadotropins in turn regulate function of the testes and ovaries. (endocrinology-journals.org)

Adult men and women at least 18 years of age with low or no gonadotropin levels. (nih.gov)
The Dmp1 response is mediated by the GnRHR, not elicited by other hypothalamic releasing factors, and is approximately 20-fold smaller in adult male pituitary cells. (nih.gov)
Background: One of the main effects of growth hormone therapy (rhGH) in the adult GH deficient patient (AGHD) is to positively modify body composition, with a reduction in fat mass (BF) and an increase in total lean mass (LM). (endocrine-abstracts.org)

In this context, serum anti-Müllerian hormone (AMH) has become popular among clinicians and is widely used in reproductive medicine ( 3 - 7 ). (frontiersin.org)
However, caution is needed when interpreting results, as certain medications and hormones can affect serum AMH levels. (frontiersin.org)
Persistently elevated serum concentration of growth hormone. (nih.gov)
Neither serum nor anterior pituitary (AP) concentrations of follicle-stimulating hormone (FSH) were affected by E2. (ncsu.edu)

We present a detailed case report of a patient with immediate signs of pituitary apoplexy after receiving a GnRHa and review the 6 previously reported cases in the literature. (nih.gov)
Magnetic resonance imaging of the brain revealed an enhancing pituitary mass with hemorrhage extending to the optic chiasm, consistent with pituitary apoplexy. (nih.gov)

Pulsatile activity can be disrupted by hypothalamic-pituitary disease, either dysfunction (i.e., hypothalamic suppression ) or organic lesions (trauma, tumor). (wikidoc.org)

Anatomy35

Organisms8

Diseases32

Chemicals and Drugs117

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Phenomena and Processes42

Disciplines and Occupations1

Information Science5

Health Care1

GnRH75

Secretion8

Testosterone27

Estrogen11

Agonist5

Puberty12

Receptors10

Luteinizing19

Axis11

Reproductive hormones5

Stimulate4

Exogenous1

Anterior pitui1

Tumors1

Testicular5

Glands5

Gland or hypothalamus2

Adenoma2

Agonists2

Human chorionic go1

Ovulation5

Signals2

Kisspeptin4

Ovarian3

Steroid3

Thyroid1

Gonads2

Androgen-binding1

Produces1

Endocrine5

Hypogonadism3

Stimulation1

Ovaries in girls1

Oxytocin1

Prolactin2

Peptide4

Progesterone2

Testes and ovaries1

Adult3

Serum4

Apoplexy2

Suppression1