• ###### Nootropil
• It was introduced in 1972, i.e. in 2 years after piracetam ( Nootropil ) developed by UCB (Belgium) has appeared in the global market. (bodyhunter.cc)
• Therapeutic efficiency of nootropil (piracetam) in two different doses has been evaluated in the open control study of 80 children with ADHD, 70 boys and 10 girls, aged 6-11 years, being divided into 3 groups. (brainmeta.com)
• ###### improves
• Piracetam is a nootropic agent i.e. a psychotropic drug which improves directly the efficiency of the higher epencephalic functions of the brain involved in cognitive processes such as those related to learning, memory, thought and consciousness, both in normal and deficient situations, without being sedative of psycho stimulant. (pharm4all.org)
• Piracetam exerts those various activities by different ways of action: it modulates brain neurotransmission, promotes metabolic conditions for neuronal plasticity & improves microcirculation through antispasmodic & haemorrheological properties, without being a vasodilator. (pharm4all.org)
• Different nootropic drugs act on the body in different ways: some directly affect nerve cell (having a direct effect on it), some - improves cerebral blood flow, having anti-hypoxic effects, causing the body to better dispose of oxygen (i.e. have an indirect effect on the brain). (crazybulkmagic.com)
• we proposed that by restoring age-related membrane alterations piracetam improves brain function and finally cognition. (frontiersin.org)
• ###### aniracetam
• Aniracetam is a fat-soluble molecule in the racetams family, anecdotally touted to be more potent than Piracetam and more catered to creativity and holistic thinking as well as reducing anxiety and depression . (examine.com)
• ###### psychotropic
• Despite different effects, all the drugs listed above provide beneficial effect on memory (i.e., nootropic action) without frank effects of conventional psychotropic and cardiotropic drugs. (bodyhunter.cc)
• ###### compounds
• compounds related to various chemical classes and groups with alternate chemical structure, piracetam-like mechanism of action and ability to facilitate learning process and improve memory. (bodyhunter.cc)
• As a specific feature of piracetam and other similar compounds, beneficial effects on cognition are usually associated with impaired brain function such as aging, hypoxia, glucose deprivation, injuries, or even neurodegeneration. (frontiersin.org)
• ###### cortical
• PIRACETAM is indicated for patients suffering from myoclonus of cortical origin, irrespective of aetiology, and should be used in combination with other anti-myoclonic therapies. (pharm4all.org)
• Pharmacologically there exist protective effects with regard to several noxes [harmful agents] and an impact on the associative cortical sphere and on hippocampal structures, which are related with learning and memory, especially when the respective functions are impaired. (smart-drugs.net)
• 1 ) Piracetam "is one of the best available drugs for treating myoclonus [severe muscle spasms] of cortical origin. (smart-drugs.net)
• ###### nefiracetam
• Subgroup 3 includes piracetam derivatives with unknown clinical efficacies, and of these nefiracetam failed to improve cognition in post-stroke patients and rolipram is currently in clinical trials as an antidepressant. (springer.com)
• ###### insufficiency
• Cognishield therapy may be required in the case of craniocerebral injuries, asthenic disorders, cerebral insufficiency, and reducing intellectual productivity. (crazybulkmagic.com)
• ###### dementia
• A meta-analysis has been performed including 19 double blind, placebo controlled studies with piracetam in patients suffering from dementia or cognitive impairment in the elderly. (brainmeta.com)
• Piracetam, the prototype of the so-called nootropic drugs' is used since many years in different countries to treat cognitive impairment in aging and dementia. (frontiersin.org)
• 4 ,5,19) Piracetam has brought improvement, or slowed deterioration, in "senile involution" dementia and Alzheimer's disease. (smart-drugs.net)
• ###### racetams
• Some however report that racetams have an agonist effect on NMDA as well have being similar too and having a similar action as GABA. (brainmeta.com)
• ###### mechanism
• The primary objective of this systematic survey is to evaluate the clinical outcomes as well as the scientific literature relating to the pharmacology, pharmacokinetics/pharmacodynamics, mechanism of action, dosing, toxicology and adverse effects of marketed and investigational drugs. (springer.com)
• To say that the mechanism of action of NDRIs is understood is a gross misrepresentation of the literature. (brainmeta.com)
• ###### acute
• 8 ) Piracetam has restored various functions (use of limbs, speech, EEC, slate of consciousness) in people suffering from acute and chronic cerebral ischemia (decreased brain blood flow). (smart-drugs.net)
• ###### analogues
• Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal. (wikipedia.org)
• Some designer drugs (research chemicals) are structural analogues of psychoactive tryptamines or phenethylamines but there are many other chemically unrelated psychoactive substances that can be considered part of the designer drug group. (wikipedia.org)
• ###### controlled substance
• This fact has led to bitter disputes about the safety of Provigil and its legal status except the U.S. where the drug is a controlled substance and is included in the list of drugs under number 4. (buyantinarcoleptic.com)
• ###### hypothesis
• Findings that piracetam enhances fluidity of brain mitochondrial membranes led to the hypothesis that piracetam might improve mitochondrial function, e.g., might enhance ATP synthesis. (frontiersin.org)
• ###### chronic
• In this publication the author reviews the most important studies, where significant effects of piracetam (chronic or single-dose treatment) were verified by means of electrophysiological methods. (brainmeta.com)
• ###### stimulants
• However, in opposition to the histaminergic action of Provigil, it often relates to the amphetamine group of stimulants due to its effect on norepinephrine levels and dopamine. (buyantinarcoleptic.com)
• The most commonly used class of drug is stimulants, such as caffeine. (wikipedia.org)
• Antidepressants Mood stabilizers Psychostimulants Nootropic drugs CNS stimulants (Abstract). (slideserve.com)
• ###### drugs
• The World Anti-Doping Agency added Provigil to the list of forbidden drugs in sport and declared Provigil as doping agent because of its ability to significantly increase the endurance and effects similar to the action of amphetamine and also due to increase in the number of athletes implicated in the use of Provigil in the international competitions. (buyantinarcoleptic.com)
• There is an increasing interest in nootropic drugs for the treatment of CNS disorders. (springer.com)
• Two of the strongest hallmarks of addiction-forming drugs is that they cause users to develop dependency and experience withdrawal when the drug use is eliminated or reduced. (noobstarter.com)
• While there are some reports of nootropic users experiencing brain fog after use is discontinued, these side effects are not considered to be akin to withdrawal effects of addiction-forming drugs. (noobstarter.com)
• There are a number of various nootropic drugs out there and all of them work in various ways. (onnootropics.com)
• 13 , 14 ) Piracetam potentiated the anticonvulsant action of various anti-epileptic drugs in both animals and man, while also eliminating cognitive deficits induced by anti-epileptic drugs in humans. (smart-drugs.net)
• Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation, hallucinations, and dream-like states or trances. (wikipedia.org)
• ###### deficits
• These studies proved objectively the positive psychoactive and cognitive effects of the drug, supporting the therapeutical indication of piracetam in such cases, where cognitive deficits are present. (brainmeta.com)
• ###### psychoactive drug
• The well-known psychoactive drug widely used in the daily clinical praxis, the piracetam has many therapeutical indications. (brainmeta.com)
• A psychedelic substance is a psychoactive drug whose primary action is to alter cognition and perception. (wikipedia.org)
• ###### disorders
• The amount of thyroid hormone secreted by breast milk during lactation (even during the treatment with high doses of the drug), is insufficient to cause any disorders in children. (liothyronine-sodium-profile.co.uk)
• Due to the effect of piracetam on platelet aggregation, caution is recommended in patients with underlying disorders of haemostasis, major surgery or severe haemorrhage. (pharm4all.org)
• The drug methylphenidate is marketed as the brand Ritalin and used to treat children and adults with ADHD. (noobstarter.com)
• ###### beneficial
• In combination with a vasodilator drug, piracetam appeared to have an additive beneficial effect on various cognitive disabilities. (springer.com)
• ###### effect
• It is a modern drug with neuroprotective effect. (crazybulkmagic.com)
• Although piracetam exhibited no long-term benefits for the treatment of mild cognitive impairments, recent studies demonstrated its neuroprotective effect when used during coronary bypass surgery. (springer.com)
• One of the most important effect of piracetam is the positive effect to the cognitive functions. (brainmeta.com)
• I would recommend you try not taking anything and see what sort of effect your wonder drug is actually having on you. (brainmeta.com)
• ###### stroke
• The drug is also prescribed after a stroke. (crazybulkmagic.com)
• The drug is extensively applied in the therapy of ischaemic stroke, aphasy as well as of dementias of several origins and age-depending cognitive disturbances. (brainmeta.com)
• 6,7) Piracetam has improved recovery from aphasia (speech impairment) after stroke. (smart-drugs.net)
• ###### placebo
• $$APIR\% = \frac{{(Bt - Tx)}} {{Bt}} \times 100$$ where Bp and Bt are placebo and test agent baselines, respectively, P is placebo and Tx is the test agent, to estimate the percentage improvement rates. (springer.com)
• ###### blood flow
• It also increases blood flow and activity in the area of the brain known for this action, the association cortex. (examine.com)
• ###### mechanisms
• Adaptogens are also known to participate in regulating homeostasis through helping to beneficially regulate the mechanisms of action associated with the HPA-axis (think back to the importance of proper HPA-axis function which you learned about in my last article on breathwork), including cortisol regulation and nitric oxide regulation. (noobstarter.com)
• ###### effects
• Unlike piracetam or fish oil, after a full bottle (Source Naturals, 120 pills at 200μg each), I noticed no side-effects, no mental improvements of any kind, and no changes in DNB scores from straight Huperzine-A. (noobstarter.com)
• ###### hypersensitivity
• Individual hypersensitivity to the product components is possible, so please pay close attention to your body response when you administer the drug for the first time. (cosmicnootropic.com)
• ###### research
• Although much of the research on Piracetam has been published in English, a large amount of Piracetam research has been published in German, French, Italian, and Russian. (smart-drugs.net)
• ###### treatment
• The drug should be carried out regularly.The duration of treatment is determined by the form of the disease. (liothyronine-sodium-profile.co.uk)
• Cognishield treatment in such cases is positive, they confirm the effectiveness and tolerability of the drug. (crazybulkmagic.com)
• ###### memory
• 8 , 12 ) Piracetam increased memory and verbal learning in dyslexic children, as well as speed and accuracy of reading, writing and spelling. (smart-drugs.net)
• 17) Elderly outpatients suffering from "age-associated memory impairment" given Piracetam showed significant improvement in memory consolidation and recall. (smart-drugs.net)
• 8 ) Piracetam reversed typical EEC slowing associated with "normal" and pathological human aging, increasing alpha and beta (fast) electroencephalograph activity and reducing delta and theta (slow) electroencephalograph activity, while simultaneously increasing vigilance, attention and memory. (smart-drugs.net)