• genetic
  • The genetic pigmentation disorder isabellinism seen in birds is derived from the colour word and is a form of leucism caused by a uniform reduction in the production and expression of melanin resulting in areas of plumage on the back of the bird, normally black, being strongly faded, or isabelline, in appearance. (wikipedia.org)
  • complexion
  • THE SOLUTION: While some forms of pigmentation can be concealed with a dab of foundation, it's sometimes not so easily dealt with - and anyway, the aim is always to have a clear complexion, with or without make-up. (stylesstar.com)
  • causes
  • Multiple causes are known, and they may range from simple iatrogenic mechanisms, such as implantation of dental amalgam, to complex medical disorders, such as Peutz-Jeghers syndrome . (medscape.com)
  • major
  • Researchers suggest that human populations over the past 50,000 years have changed from dark-skinned to light-skinned and vice versa as they migrated to different UV zones, and that such major changes in pigmentation may have happened in as little as 100 generations (≈2,500 years) through selective sweeps. (wikipedia.org)
  • condition
  • The skin's pigmentation (in this condition) has been described as uniformly gray, grayish purple, slate gray, or grayish blue, and is usually limited to exposed portions of the body. (wikipedia.org)
  • knowledge
  • September 1993-The NIH Revitalization Act of 1993 (P.L. 103-43) directed NIAMS to establish "an information clearinghouse on osteoporosis and related bone disorders to facilitate and enhance knowledge and understanding on the part of health professionals, patients, and the public through the effective dissemination of information. (wikipedia.org)
  • known
  • Those born with a disorder known as PKU, or phenylketonuria, have a buildup of phenylalanine due to a metabolic predisposition that prevents them from using it for energy. (livestrong.com)