• retina
  • The mice also showed significant depletion of their retinoid content in retinal pigment epithelium (RPE) and neurosensory retina, including a 95% reduction in retinyl esters. (arvojournals.org)
  • protein
  • The resulting EDNRB protein is unable to fulfill its role in the development of the embryo, limiting the migration of the melanocyte and enteric neuron precursors. (wikipedia.org)
  • patterns
  • Genes that affect the distribution of white and pigmented coat, skin and eye color create patterns such as roan, pinto, leopard, white, and even white markings. (wikipedia.org)
  • hair
  • Melanin is a complex molecule responsible for the pigment in the skin, hair and eyes. (skininc.com)
  • Different types of laser treatments may also be effective in elimination or reduction of hyperpigmentation, though the results of laser treatments for both hair and pigment reduction appear to be highly variable. (wikipedia.org)
  • Hair acquires pigment from melanocytes in the root bulb, which deposit melanosomes into the growing hair structure. (wikipedia.org)
  • In some cases, foals born with residual non-white hair may lose some or all of this pigment with age, without the help of the gray factor. (wikipedia.org)
  • Nor does the champagne gene remove all pigment from the skin and hair, as in albinism. (wikipedia.org)
  • embryo
  • The migration of nerve- and melanocyte-precursors from the top of the embryo to their eventual destinations is carefully controlled by regulatory genes. (wikipedia.org)
  • white
  • This results in uneven white patches that have no pigment, but the skin feels like normal. (limamemorial.org)
  • This is a handheld ultraviolet light that causes the areas of skin with less pigment to glow bright white. (limamemorial.org)
  • Genetic conditions which affect more than one physical trait-in the case of lethal white syndrome, both pigment cells and enteric nerve cells-are termed pleiotropic. (wikipedia.org)
  • In addition, the hooves are most often white, but may have striping if there is pigmented skin on the coronary band just above the hoof. (wikipedia.org)
  • Unlike the genes underlying tobiano, dominant white, frame overo spotting and the Leopard complex common to the Appaloosa, the champagne gene does not affect the location of pigment-producing cells in the skin. (wikipedia.org)
  • Claude appears completely white because he lacks the pigment melanin. (wikipedia.org)
  • occurs
  • Labeled clones are arrayed along the proximal-distal axis of the fin, and melanocyte time-of-differentiation lineage assays show that although most of the pigment pattern growth is at the distal edge of the fin, significant growth also occurs proximally. (biologists.org)
  • migration
  • NMDA-R is an important glutamate receptor implicated in neurogenesis, neuronal migration, maturation and cell death, thus we investigated the role of NMDA-R potentiation by glutamate/KCN and its inhibition by ketamine in the behavior of fish scale melanocytes in vitro. (springer.com)
  • adult
  • We use the pigment pattern of the adult zebrafish fin, with a variety of clonal and lineage analyses, to address these issues. (biologists.org)
  • These analyses build a comprehensive picture for how MSCs are established and grow to form the pigment stripes of the adult zebrafish fins. (biologists.org)
  • Here, we use clonal and lineage analyses to study the contribution of melanocyte lineages to the adult fin. (biologists.org)
  • form
  • This is aimed at establishing the regulatory role of NMDA-R in this cell type (melanocytes isolated form Tilapia) in a similar manner to what is observable in the mammalian neurons. (springer.com)
  • suitable
  • This study employs the manipulation of N-Methyl-D-Aspartate Receptor (NMDA-R), a major receptor in neuronal development, in the process formation pattern of the melanocyte in order to create a suitable model to depict cellular process elongation and shortening in pigmented adrenergic cells. (springer.com)
  • GFP) ( Johnson and Krieg, 1995 ) with ubiquitous expression, making it suitable to compare lineage relationship of melanocytes with other cell types in the fin. (biologists.org)
  • specific
  • Recent advances have demonstrated that melanocytes and retinal pigmented epithelial (RPE) cells exhibiting the characteristics of their natural counterparts can be induced from undifferentiated ES cells grown on monolayers of specific stromal cell lines or by using a combination of Wnt3a, Endothelin-3 and SCF. (wiley.com)
  • include
  • These include large tumor size, ciliary body involvement, presence of orange pigment overlying the tumor, and older patient age. (wikipedia.org)