• The most common complication of renal osteodystrophy is fracture, which may be insufficiency fractures through osteomalacic bone or pathologic fractures through brown tumors or amyloid deposits. (medscape.com)
  • Osteosarcoma, Ewing sarcoma and chondrosarcoma represent 70% of primary bone tumor diagnoses, and malignant primary bone tumors represent around 3,300 new cases annually in the United States [5,6]. (crimsonpublishers.com)
  • Clinical features, incidence, and survivorship of malignant primary bone tumors [5-7]. (crimsonpublishers.com)
  • Skeletal deformity can occur in the vertebral bodies and skull (basilar invagination), and fractures can occur in the vertebrae and long bones. (medscape.com)
  • Spine infections are rare infections that can involve the intervertebral disc space (discitis), the vertebral bones, the spinal canal or adjacent soft tissues. (wheelessonline.com)
  • Vertebral osteomyelitis refers to an infection of the vertebral bones in the spine. (wheelessonline.com)
  • There are multiple ways that bacteria can spread into the vertebral column. (wheelessonline.com)
  • Mildly affected patients may present with nonspecific bone pain and tenderness and possibly hypotonia. (medscape.com)
  • As many as 30% of myeloma patients may present with a pathologic fracture, and up to two-thirds with bone pain alone as the initial symptom of disease [7]. (crimsonpublishers.com)
  • The histopathologic findings of renal osteodystrophy are commonly used to further classify the condition into high bone turnover states, such as osteitis fibrosa and hyperparathyroidism, and low bone turnover states, such as adynamic bone disease or heavy metal-induced osteomalacia. (medscape.com)
  • Primary bone lesions are more commonly identified in patients under the age of 40, and can be subdivided into benign and malignant lesions. (crimsonpublishers.com)
  • Renal osteodystrophy may also present with nonspecific signs and symptoms, including weakness, bone pain, and skeletal deformity. (medscape.com)
  • Technically considered a plasma cell dyscrasia, multiple myeloma is the most common primary malignancy of bone [7,8]. (crimsonpublishers.com)
  • The presence of multiple osteolytic bone lesions is a defining trademark of the disease. (crimsonpublishers.com)