• Topoisomerase I-binding arginine-serine-rich prote. (wfleabase.org)
  • Hepatocyte growth factor receptor (c-Met), a member of tyrosine protein kinase receptors (TPKR), is phosphorylated during LPLI-induced proliferation, but tumor necrosis factor alpha (TNF-alpha) receptor has not been affected. (biomedcentral.com)
  • Here we report that activation of GABA B receptors significantly inhibits Akt/GSK-3 signaling in a β-arrestin-dependent pathway. (biomedcentral.com)
  • Agonist stimulation of GABA B receptors enhances the phosphorylation of Akt (Thr-308) and enhances the phosphorylation of GSK-3α (Ser-21)/β (Ser-9) in both HEK-293T cells expressing GABA B receptors and rat hippocampal slices. (biomedcentral.com)
  • Clozapine also increased 3 H]-CGP54626A binding at GABA B R1 subunit when HEK293 cells overexpressed GABA B receptors, highlighting a potential therapeutic target for clozapine. (biomedcentral.com)
  • ATM is a serine/threonine protein kinase and a member of the PI3K/P14K-kinase family. (bio-rad-antibodies.com)
  • There are two highly homologous GSK-3 enzymes, GSK-3α and GSK-3β, derived from separate genes. (biomedcentral.com)
  • Recently, a large number of signaling proteins reported play an important key role in the process of LPLI-induced cell proliferation, probably due to the fact that the molecular events they are involved in are the basic response of the cells to extracellular stimuli. (biomedcentral.com)
  • ATM is a cell cycle checkpoint kinase and is important in the DNA damage response. (bio-rad-antibodies.com)
  • GSK-3 is a protein kinase originally identified and named for its ability to phosphorylate and inactivate the metabolic enzyme glycogen synthase [ 11 ]. (biomedcentral.com)