Dihydroxyacetone phosphateGlycerol 3-phospTrioseCholineElevating Calcium and phosphateTricalcium phosphateEnzymeGlyceraldehydeHigh-energy phDHAPCalcium gluconateParenteral nutritionSodium PyruvateMagnesium citrateFattyMitochondrialLipid metabolism0.05MetabolicSubstratesGPDHNADHGPD2AdditionallyMoleculesGlycolysisMonohydrateOrganicConsistsAcidBackboneGroupMajorMainActivityProduce
Dihydroxyacetone phosphate10
- Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (a.k.a. glycerone phosphate, outdated) to sn-glycerol 3-phosphate. (wikipedia.org)
- Through the reduction of dihydroxyacetone phosphate into glycerol 3-phosphate, GPDH allows the prompt dephosphorylation of glycerol 3-phosphate into glycerol. (wikipedia.org)
- One way to shuttle this reducing equivalent across the membrane is through the Glycerol-3-phosphate shuttle, which employs the two forms of GPDH: Cytosolic GPDH, or GPD1, is localized to the outer membrane of the mitochondria facing the cytosol, and catalyzes the reduction of dihydroxyacetone phosphate into glycerol-3-phosphate. (wikipedia.org)
- In conjunction, Mitochondrial GPDH, or GPD2, is embedded on the outer surface of the inner mitochondrial membrane, overlooking the cytosol, and catalyzes the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate. (wikipedia.org)
- GPD1 consists of two subunits, and reacts with dihydroxyacetone phosphate and NAD+ though the following interaction: Figure 4. (wikipedia.org)
- Mitochondrial glycerol-3-phosphate dehydrogenase (GPD2), catalyzes the irreversible oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate and concomitantly transfers two electrons from FAD to the electron transport chain. (wikipedia.org)
- Oxidation of cytoplasmic NADH by the cytosolic form of the enzyme creates glycerol-3-phosphate from dihydroxyacetone phosphate. (wikipedia.org)
- Glycerol 3-phospate may then be converted by dehydrogenation to dihydroxyacetone phosphate (DHAP) by the enzyme glycerol-3-phosphate dehydrogenase. (hmdb.ca)
- We reviewed a few plausibly organic syntheses of phospholipids under prebiotic conditions with special attention paid to the starting materials as pro-chiral dihydroxyacetone and dihydroxyacetone phosphate (DHAP), which are the key molecules to break symmetry in phospholipids. (mdpi.com)
- In this shuttle, glycerol 3-phosphate is converted to dihydroxyacetone phosphate, allowing the transfer of reducing equivalents from the cytosolic NADH to the mitochondrial electron transport chain. (pediaa.com)
Glycerol 3-phosp1
- The glycerol 3-phosphate shuttle is used to rapidly regenerate NAD+ in the brain and skeletal muscle cells of mammals (wikipedia). (hmdb.ca)
Triose4
- Glycerol 3-phosphate is produced from glycerol, the triose sugar backbone of triglycerides and glycerophospholipids, by the enzyme glycerol kinase. (hmdb.ca)
- DHAP can then be rearranged into glyceraldehyde 3-phosphate (GA3P) by triose phosphate isomerase (TIM), and feed into glycolysis. (hmdb.ca)
- Glyceraldehyde 3-phosphate, also known as triose phosphate , is a key molecule in cellular metabolism. (pediaa.com)
- Gene frequencies were monitored at 3 enzyme loci - alcohol dehydrogenase, triose phosphate isomerase, α-glycerophosphate dehydrogenase - associated with the metabolism of ethanol and acetaldehyde. (edu.au)
Choline1
- A member of the class of phosphocholines that is the choline ester of sn -glycero-3-phosphate. (ebi.ac.uk)
Elevating Calcium and phosphate1
- It is thought that calcium glycerophosphate may act through a variety of mechanisms to produce an anti-caries effect , These include increasing acid-resistance of the enamel, increasing enamel mineralization, modifying plaque, acting as a pH-buffer in plaque, and elevating Calcium and phosphate levels. (toothpastetop.com)
Tricalcium phosphate1
- Anti-caking agent: tricalcium phosphate. (synergiashop.com)
Enzyme4
- The reactions catalyzed by cytosolic (soluble) and mitochondrial GPDH are as follows: There are two forms of GPDH: The following human genes encode proteins with GPDH enzymatic activity: Cytosolic Glycerol-3-phosphate dehydrogenase (GPD1), is an NAD+-dependent enzyme that reduces dihydroxyacetone phosphate to glycerol-3-phosphate. (wikipedia.org)
- It is generated through the enzymatic conversion of glyceraldehyde 3-phosphate by the enzyme glyceraldehyde 3- phosphate dehydrogenase. (pediaa.com)
- During glycolysis, glyceraldehyde 3-phosphate is generated through the enzymatic conversion of glucose- 6 phosphate by the enzyme phosphoglucose isomerase. (pediaa.com)
- Treatment-and-prophylactic R.O.C.S. toothpaste for adults containing the MINERALIN® complex, which is a patented combination of ingredients: the natural proteolytic enzyme bromelain, xylitol, calcium glycerophosphate and magnesium chloride. (toothpastetop.com)
Glyceraldehyde8
- However, glycerol-3-phosphate dehydrogenase is not the same as glyceraldehyde 3-phosphate dehydrogenase (GAPDH), whose substrate is an aldehyde not an alcohol. (wikipedia.org)
- It is commonly confused with the similarly named glycerate 3-phosphate or glyceraldehyde 3-phosphate. (hmdb.ca)
- The main difference between glycerol 3-phosphate and glyceraldehyde 3- phosphate is that glycerol 3-phosphate is mainly involved in lipid synthesis, while glyceraldehyde 3-phosphate is involved in glycolysis . (pediaa.com)
- Glycerol 3-phosphate and glyceraldehyde 3-phosphate are both important molecules taking part in various metabolic processes in living organisms, particularly in glycolysis and lipid metabolism. (pediaa.com)
- Glyceraldehyde 3 phosphate is mainly formed during the process of glycolysis, the central metabolic pathway. (pediaa.com)
- One other function of glyceraldehyde 3-phosphate is its involvement in energy metabolism. (pediaa.com)
- Glyceraldehyde serves as a crucial intermediate in these reactions, facilitating the transfer of high-energy phosphate groups and electrons to produce ATP and reducing equivalents such as NADH. (pediaa.com)
- Glyceraldehyde 3-phosphate plays a vital role in the anabolic pathways, mainly in the biosynthesis of various important molecules. (pediaa.com)
High-energy ph1
- There were no significant differences between control and treated rats for any high-energy phosphate source. (cdc.gov)
DHAP1
- The phosphate group of DHAP is half-encircled by the side-chain of Arg269, and interacts with Arg269 and Gly268 directly by hydrogen bonds (not shown). (wikipedia.org)
Calcium gluconate2
- These parenteral nutrition formulations were prepared by adding 4 mmol/dL phosphorus and 3.712 mmol/dL calcium using as sources solutions of 1 mmol/mL glycerophosphate and 10% calcium gluconate (w/v) and kept at a temperature (5 + 3oC) for 0, 6, 12 and 24 hours, followed by 24 hours at room temperature of 24 + 3oC. (usp.br)
- We conclude that sodium glycerophosphate, when added to parenteral nutrition formulations together with calcium gluconate in the amounts and under the conditions tested here did not present in vitro incompatibility. (usp.br)
Parenteral nutrition2
- A sterile and apyrogenic sodium glycerophosphate solution for intravenous administration, not commercially available in Brazil, was developed and added to standard parenteral nutrition formulations used at the University Hospital, Faculty of Medicine of Ribeirão Preto, University of São Paulo, in order to supply phosphorus together with calcium. (usp.br)
- Title: Calcium chloride and sodium phosphate in neonatal parenteral nutrition containing TrophAmine: precipitation studies and aluminum content. (aablocks.com)
Sodium Pyruvate1
- 3) chondrogenic medium: 10?ng/ml TGF1, 11?mg/ml sodium pyruvate, and 50?mg/ml ascorbate-2-phosphate. (skinmicrobiomecongressca.com)
Magnesium citrate1
- Title: Budget-impact model for colonoscopy cost calculation and comparison between 2 litre PEG+ASC and sodium picosulphate with magnesium citrate or sodium phosphate oral bowel cleansing agents. (aablocks.com)
Fatty1
- During triglyceride synthesis, glycerol 3-phosphate combines with three fatty acid molecules through ester linkages, forming a triglyceride molecule. (pediaa.com)
Mitochondrial2
- The cytosolic together with the mitochondrial glycerol-3-phosphate dehydrogenase work in concert. (wikipedia.org)
- Once the glycerol-3-phosphate has moved through the outer mitochondrial membrane it can then be oxidised by a separate isoform of glycerol-3-phosphate dehydrogenase that uses quinone as an oxidant and FAD as a co-factor. (wikipedia.org)
Lipid metabolism2
- Glycerol-3-phosphate dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism. (wikipedia.org)
- Another crucial function of glycerol 3-phosphate lies in lipid metabolism. (pediaa.com)
0.051
- After achieving confluence, cells had been turned to osteogenic differentiation moderate (DMEM with 15% FBS, 0.1 M dexamethasone, 10 mM -glycerophosphate, and 0.05 mM L-ascorbic acid-2-phosphate). (scapca.org)
Metabolic2
- Predicted to be involved in glycerol catabolic process and glycerol-3-phosphate metabolic process. (nih.gov)
- Glycerol 3-phosphate is a chemical intermediate in the glycolysis metabolic pathway. (hmdb.ca)
Substrates1
- Of the substrates, only the increase in alpha-glycerophosphate in the high dose rats was significant. (cdc.gov)
GPDH2
- Older terms for glycerol-3-phosphate dehydrogenase include alpha glycerol-3-phosphate dehydrogenase (alphaGPDH) and glycerolphosphate dehydrogenase (GPDH). (wikipedia.org)
- Seasonal and spatial variation in gene frequencies at 3 diallelic loci : alcohol dehydrogenase (Adh), glycerophosphate dehydrogenase (Gpdh) and triosephosphate isomerase (Tpi), have been studied in an orchard population of D. melanogaster. (edu.au)
NADH1
- In subsequent steps of glycolysis, glycerol 3-phosphate is further metabolized to generate ATP and NADH , a coenzyme involved in cellular respiration. (pediaa.com)
GPD21
- Orthologous to human GPD2 (glycerol-3-phosphate dehydrogenase 2). (nih.gov)
Additionally1
- Additionally, glycerol 3-phosphate plays a role in the glycerol phosphate shuttle mechanism, which facilitates the transport of reducing equivalents across the cellular membranes. (pediaa.com)
Molecules1
- This phosphate group enables glycerol 3-phosphate to participate in phosphorylation reactions and interact with other molecules in cellular processes. (pediaa.com)
Glycolysis2
- Glycerol 3-phosphate is synthesized through various pathways, including glycolysis, glycerol phosphate shuttle, and gluconeogenesis pathway. (pediaa.com)
- In glycolysis, glycerol 3- phosphate is an intermediate formed during the breakdown of glucose. (pediaa.com)
Monohydrate1
- Title: Citrate, not phosphate, can dissolve calcium oxalate monohydrate crystals and detach these crystals from renal tubular cells. (aablocks.com)
Organic1
- belongs to the class of organic compounds known as 1-acylglycerol-3-phosphates. (ymdb.ca)
Consists1
- Glycerol 3-phosphate consists of a glycerol backbone and a three-carbon molecule with a phosphate group attached to the third carbon atom. (pediaa.com)
Acid3
- This study aims to investigate the effects of a modified, balanced crystalloid including phosphate in a perioperative setting in order to maintain a stable electrolyte and acid-base homeostasis in the patient. (biomedcentral.com)
- Secondary endpoints are measurement of serum phosphate levels, other acid-base parameters such as the strong ion difference (SID), the onset and severity of postoperative nausea and vomiting (PONV), electrolyte levels and their excretion in the urine, monitoring of renal function and glycocalyx components, haemodynamics, amounts of catecholamines and other vasopressors used and the safety of the infusion regime. (biomedcentral.com)
- This study aims to investigate the effectivity and safety of a new crystalloid solution by adding sodium glycerophosphate to a standardized crystalloid preparation in order to maintain a balanced perioperative acid-base homeostasis. (biomedcentral.com)
Backbone1
- They share a common phosphate group and a 3-carbon backbone. (pediaa.com)
Group1
- This is a single-centre, open-label, randomized controlled trial involving two parallel groups of female patients comparing a perioperative infusion regime with sodium glycerophosphate and Jonosteril® (treatment group) or Jonosteril® (comparator) alone. (biomedcentral.com)
Major1
- This graph shows the total number of publications written about "Glycerophosphates" by people in this website by year, and whether "Glycerophosphates" was a major or minor topic of these publications. (wakehealth.edu)
Main2
- One of the main roles of glycerol 3-phosphate is its involvement in energy metabolism. (pediaa.com)
- Glycerol 3-phosphate serves as a precursor for the production of ATP , the main energy currency of the cell. (pediaa.com)
Activity1
Produce1
- Bacteria thriving at extremely high pH tend to produce more cardiolipin (CL) as well as bis-mono-acyl-glycero-phosphate (BMP) 3 . (nature.com)