• erections
  • Nocturnal erections have been proposed to play a protective role on the trabecular tissue, increasing tissue oxygenation, specifically during long periods of sexual abstinence.5 As orally taken vasoactive drugs, such as sildenafil and phentolamine have shown to be effective in enhancing erectile capabilities,6,7 it was postulated that it may be possible to pharmacologically manipulate nocturnal erections with regular administration of such agents before sleep. (spotidoc.com)
  • While phentolamine was never proven to create erections by itself, Zonagen claimed that its formulation, simply phentolamine administered orally instead of in pill form, would work. (wikipedia.org)
  • propranolol
  • In all three series, measurements of mean heart rate and blood pressure were taken in the control state, after parasympathetic denervation with bilateral cervical vagotomies, and after autonomic blockade with propranolol (1 mg/kg) and phentolamine (0.5 mg i.v.). In series 1, we characterized the role of alpha-adrenergic receptors in early newborn puppies by investigating the hemodynamic effects of phentolamine alone in five early newborn puppies. (ahajournals.org)
  • Two examples of competitive adrenergic antagonists are propranolol and phentolamine. (wikipedia.org)
  • Phentolamine Propranolol Nebivilol Atenolol Oxprenolol Metoprolol Timolol Pindolol Nadolol Pindolol Esmolol Acebutolol Sotalol Talinolol Betaxolol Labetalol Carvedilol Adrenergic antagonists have inhibitory or opposing effects on the receptors in the adrenergic system. (wikipedia.org)
  • Placebo
  • All patients received oral phentolamine (VasomaxTM) at a dose of 40 mg and placebo for three consecutive nights respectively and were submitted to nocturnal penile tumescence and rigidity monitoring (NPTR) with the Rigiscan1 device. (spotidoc.com)
  • blockers
  • Like the selective α1 blockers, phentolamine causes a relaxation of systemic vasculature, leading to hypotension. (wikipedia.org)
  • Phentolamine should only be given to patients who do not fully respond to benzodiazepines, nitroglycerin, and calcium channel blockers. (wikipedia.org)
  • Non-selective α-adrenergic receptor antagonists include: Phenoxybenzamine Phentolamine Tolazoline Trazodon Selective α1-adrenergic receptor antagonists include: Alfuzosin Doxazosin Prazosin (inverse agonist) Tamsulosin Terazosin Silodosin Selective α2-adrenergic receptor antagonists include: Atipamezole Idazoxan Mirtazapine Yohimbine Finally, the agents carvedilol and labetalol are both α and β-blockers. (wikipedia.org)
  • Oral
  • Administration of oral phentolamine before sleep was associated with a statistically significant increase in the number of erectile events with rigidity 60% lasting 10 min (P ¼ 0.02), as well as the rigidity activity units (RAU) value per hour sleep, both at the base (P ¼ 0.023) and the tip of the penis (P ¼ 0.019). (spotidoc.com)
  • It is concluded that oral phentolamine administered before sleep enhanced NPTR parameters associated with the quality of the erectile events. (spotidoc.com)
  • diagnostic
  • Determination of blood catecholamine concentrations, urinary assay of catecholamines, or other biochemical assays are the safest and most reliable diagnostic methods and they have largely replaced phentolamine and other pharmaceutical tests. (drugs.com)
  • decrease
  • In early newborn puppies, phentolamine alone resulted in a 24% decrease (p less than 0.005) in blood pressure, compared with a 54% decrease (p less than 0.005) in early newborn puppies preexposed to VIP infusion. (ahajournals.org)
  • The medication phentolamine can be injected at the site to try to decrease the risk of tissue death. (wikipedia.org)