Mice, KnockoutPhenotypeGene Knockout TechniquesMice, Inbred C57BLGenotypeDextromethorphanDisease Models, AnimalBiological Ontologiesalpha 1-Antitrypsin DeficiencyCytochrome P-450 Enzyme SystemMephenytoinDebrisoquinSulfamethazineQuantitative Trait LociDNA ShufflingMutationCytochrome P-450 CYP2D6Mice, TransgenicCytochrome P-450 CYP1A2Aryl Hydrocarbon HydroxylasesImmunophenotyping