• disorders
  • Even though these syndromes share some overlapping features, genotype-phenotype correlations are well established for each of these, supporting the idea that they represent clinically distinct disorders. (els.net)
  • LEOPARD
  • b) Deep palmar and plantar creases and (c) Generalised multiple lentigines in a patient with NS with multiple lentigines/Leopard syndrome. (els.net)
  • features
  • High-resolution ultrasound in pregnant women with a family history of Noonan's may detect features suggestive of the syndrome. (lymphedemapeople.com)
  • When the medical world first learned about Prader-Willi syndrome in 1956, doctors had no idea what caused people to have this collection of features and problems that we now know as PWS. (lymphedemapeople.com)
  • patients
  • King and Denborough (1972) had previously described a subgroup of King-Denborough syndrome patients with elevated CPK levels. (mhaus.org)
  • 2001) reported a case series of 60 Noonan syndrome patients who underwent surgery to fix spinal deformities. (mhaus.org)
  • One of the coauthors wrote in a letter to the Lancet (Pinsky, 1972) that "it can be argued that most patients with the syndrome are not at risk. (mhaus.org)
  • We recently reviewed the anesthetic records (at the Children's Hospital of Philadelphia) of patients with Noonan syndrome that received triggering anesthetic agents. (mhaus.org)
  • Bleeding diathesis occurs in around half of patients (not an associated feature of Turner syndrome), and infertility is not associated with Noonan syndrome. (oncologynurseadvisor.com)
  • condition
  • Though an early description of the syndrome is credited to a Russian medical student, Koblinsky, at the Russian/Estonian University at Dorpat, the condition is named after an American cardiologist, Jacquline A. Noonan. (lymphedemapeople.com)
  • possible
  • Hunter A, Pinsky L. An evaluation of the possible association of malignant hyperpyrexia with the Noonan syndrome using serum creatine phosphokinase levels. (mhaus.org)