PharmacologyPharmacology, ClinicalSignal TransductionProtein Sorting SignalsMolecular Sequence DataPhosphorylationReceptors, Antigen, T-CellReceptors, Antigen, B-CellAmino Acid SequenceCell LineAdaptor Proteins, Signal TransducingLigandsTyrosineProtein-Tyrosine KinasesReceptors, G-Protein-CoupledCells, CulturedMice, KnockoutMice, Inbred C57BLTransfectionBase SequenceRecombinant Fusion ProteinsLymphocyte Specific Protein Tyrosine Kinase p56(lck)Immunological SynapsesModels, BiologicalEnzyme ActivationMutationReceptors, Cell SurfaceMembrane ProteinsDose-Response Relationship, DrugReceptors, AntigenCalciumIntracellular Signaling Peptides and ProteinsSialic Acid Binding Ig-like Lectin 2Lymphocyte ActivationProtein Tyrosine PhosphatasesMAP Kinase Kinase Kinase 2T-LymphocytesTumor Cells, CulturedRNA, MessengerCell DifferentiationGenes, RAG-1DNA-Binding ProteinsGTP-Binding ProteinsProtein Tyrosine Phosphatase, Non-Receptor Type 6Protein Structure, TertiaryB-LymphocytesPhosphoproteinsType C PhospholipasesReceptors, Interleukin-7Signal Processing, Computer-AssistedZAP-70 Protein-Tyrosine KinaseProto-Oncogene Proteins c-vavRecombinant ProteinsTime Factorssrc Homology DomainsCell MembraneMice, TransgenicGene Expression RegulationAntigens, CDKineticssrc-Family KinasesCarrier ProteinsProteinsProto-Oncogene Proteins c-fynPhospholipase C gammaGTP-Binding Protein alpha Subunits, Gq-G11Binding SitesProtein-Serine-Threonine KinasesBlotting, WesternMyeloid Differentiation Factor 88Phosphatidylinositol 3-KinasesProto-Oncogene ProteinsCell DivisionArrestinsSequence Homology, Amino AcidReceptor, Epidermal Growth FactorMitogen-Activated Protein KinasesGTP-Binding Protein alpha Subunits, Gi-GoNuclear Localization SignalsProtein BindingEnzyme InhibitorsCricetinaeTranscription FactorsPhosphotyrosineJurkat CellsReceptor, InsulinReceptors, ImmunologicCyclic AMPInterleukin-7Membrane MicrodomainsAdaptor Proteins, Vesicular TransportTranscription, GeneticCOS CellsB-Lymphocyte SubsetsToll-Like ReceptorsGRB2 Adaptor ProteinInterleukin-1 Receptor-Associated KinasesReceptors, CytokineIsoenzymesMice, Inbred BALB C