Its seeds showed that alkaloids belonging to the β-carboline family such as harmine, harmaline, Harman, harnol and harmalol are responsible for a wide range of pharmacological effects. (novapublishers.com)
Ayahuasca is prepared from the Psychotria viridis bush that contains the serotonergic 2A receptor agonist N , N -dimethyltryptamine (DMT) and the Banisteriopsis caapi liana that contains β-carboline alkaloids such as harmine, harmaline, and tetrahydroharmine (Palhano-Fontes et al. (springer.com)
Harmine and harmaline are selective and reversible inhibitors of monoamine oxidase A (MAO-A), while tetrahydroharmine is a weak serotonin reuptake inhibitor (SRI). (psychonautwiki.org)
Alkaloids2
Passionflower contains the variety of active compounds such as alkaloids, such as harmine, which is a beta-carboline alkaloid and has been known to show the variety of pharmacological effects. (planetayurveda.com)
Unfortunately, this species of Mimosa, like others, contains alkaloids, which may limit its pharmacological development as an OTC drug ("over the counter drug") due to national and international legal requirements" ii . (edabea.com)
The pharmacological effects of specific β-carbolines are dependent on their substituents. (wikipedia.org)
The pharmacological effects of harmine have been attributed mainly to its central monoamine oxidase (MAO) inhibitory properties. (wikipedia.org)
Since harmine also antagonizes N-methyl-d-aspartate (NMDA) receptors, some researchers speculatively attributed the rapid improvement in patients with Parkinson's disease to these antiglutamatergic effects. (wikipedia.org)
It is not to be misconstrued as recommendation for use, but should serve as an overview of the pharmacological and toxicological effects. (provithor.com)
Absence of usual pharmacological effects of neuro-psychotropic drugs. (bengreenfieldlife.com)
The genetic variability in populations from distinct origin and differences in the composition of venom -a little explored topic- could influence the pharmacological effects of products used in medical practice. (jppres.com)
Compounds1
We are engaged in offering Chemical Compounds which includes hydroxy flavone, gossypin, vanillinacetate, chlorogenic acid, bromovanillin and harmine pure.All these chemical compounds can exist as solids, at low enough temperatures & may also exist as liquids, gases, and even plasmas. (pcchem.net)
Active1
In early 20th century, European pharmacists identified harmine as the active substance. (wikipedia.org)
Time1
However, the advent of synthetic anticholinergic drugs at that time led to the total abandonment of harmine. (wikipedia.org)
Medical1
Learn much more about the pharmacological phytochemicals produced by Lemongrass , and its medical benefits here! (botanicalguides.com)
Inhibitors1
Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases: M.F. Lindberg, et al. (adipogen.com)
Mechanism1
30. A preliminary study on the neurotoxic mechanism of harmine in Caenorhabditis elegans. (nih.gov)
Mice2
Furthermore, harmine supports the survival of dopaminergic neurons in MPTP-treated mice. (wikipedia.org)
29. Modification by levo-propranolol of tremors induced by harmine in mice. (nih.gov)
Activities2
The pharmacological activities of more than half of these chemicals are yet unknown. (bvsalud.org)
Polyacetylenes and coumarins are the most important bioactive compounds responsible for pharmacological activities, such as antiproliferative, anti-oxidation, anti-inflammatory, antibacterial, antitussive, immune regulation and analgesic. (bvsalud.org)
Found2
Although Anadenanthera peregrina is considered the primary plant source for snuff used by the Piaroa of southern Venezuela, due to their snuff testing positive for bufotenine, one Piaroa snuff sample analyzed was also found to contain harmine (Smet & Rivier 1985, in Torres & Repke 2006). (erowid.org)
As I read further, I discovered that, while the authors did claim to find harmine in at least one adult mummy believed to be a snuff user, as well as in the mummy of a one-year-old infant (suspected of not being a snuff user), they found no tryptamines in any of their mummies. (erowid.org)