Pharmaceuticals small molecule libraries. Medical search. Frequent questions

Quantum 3.1 also helps detect potential moderate-to-serious adverse activity, additional unexpected activity and broad relative selectivity for a library of compounds by screening them against several hundred ADME/TOX-associated proteins. (technologynetworks.com)
At the 2007 SBS meeting in Montreal, Dr. Mohammed Kashem from Boehringer Ingelheim Pharmaceuticals, first reported similar findings when he compared Kinase-Glo and a second commercially available ATP-detection luminescent reagent for tolerance to interference by compounds in the BI screening deck. (wtnnews.com)
SBS 2007 Poster #PST1C016) that Kinase-Glo is much less prone to interference from library compounds than PKLight reagent, making it a superior ATP-detection reagent for identifying small-molecule modulators of kinases by HTS. (wtnnews.com)
Over 250 billion tiny compounds may be found in X-libraries, Chem's a leader in DEL technology. (medgadget.com)
By identifying compounds based on their mass ID, ASMS provides a direct readout of the bound molecule, thereby instilling confidence in initial hits. (ddw-online.com)
How much to compress a library can be influenced by the quality of the library, purity, devoid of bad actors and PAINS compounds, the throughput of the ASMS approach and the target of interest. (ddw-online.com)
Keeping the general workflow in mind, here are three popular and emerging approaches that offer key solutions for identifying small molecule binding compounds to diverse targets. (ddw-online.com)
To accelerate screens, most users of ALIS utilise highly compressed libraries with hundreds or thousands of compounds per reaction. (ddw-online.com)
Pharmaceutical companies have vast libraries of compounds which can be screened in the hunt for potential medicines. (worldpharmanews.com)
As part of the European Lead Factory, the 7 participating pharmaceutical companies will contribute at least 300 000 chemical compounds from their corporate chemical collections. (worldpharmanews.com)
A library of an estimated additional 200 000 novel compounds will be developed jointly by academia and SMEs. (worldpharmanews.com)
Together, the two libraries will form a Joint European Compound Collection consisting of up to half a million compounds that will be accessible to all project partners and to public organisations offering promising new targets for drug discovery screening. (worldpharmanews.com)
Both the sites in Scotland and the Netherlands will run state of the art facilities for compound logistics and high throughput screening to respectively handle the 500 000-strong compound library and to evaluate new compounds that are active against the novel targets. (worldpharmanews.com)
We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a 'switched off' or inactivated conformation. (vcnewsdaily.com)
In response to the COVID-19 pandemic, we began a project in March 2020 to identify small molecule inhibitors of SARS-CoV-2 enzymes from a library of chemical compounds containing many established pharmaceuticals. (crick.ac.uk)
HitGen's DELs contain more than 90 billion novel, diverse, drug-like small molecule and macrocycle compounds. (hitgen.com)
The TSRI researchers demonstrated the technique to find "ligands" (binding partners) for many proteins previously thought to bind poorly to small molecules that can be used to determine the functions of their protein targets and can serve as starting compounds for the development of drugs. (innovationtoronto.com)
For initial screens to find potential ligands, such "fragment" molecules are much more efficient than drug-sized molecules, requiring much smaller libraries of compounds for a thorough search. (innovationtoronto.com)

Quantum claims that, using Quantum 3.1, researchers can calculate the IC50 of protein-ligand and protein-protein complexes, perform ligand docking, perform virtual screening of small-molecule libraries, analyze large-scale protein movements, perform de novo drug design and calculate the solvation energy and solubility. (technologynetworks.com)
Nicotine is a small molecule ligand that binds to and gates nicotinic acetylcholine receptors, and a thorough understanding of nicotine structure could aid efforts to elucidate receptor structure-function relationships and design new pharmaceuticals. (caltech.edu)
The NMR Facility provides support for a full range of NMR studies into the structure, dynamics, kinetics, and reaction mechanisms of small organic molecules, pharmaceuticals and biomolecules, in addition to ligand binding studies and metabolomics. (umaryland.edu)
The new method is partly based on an approach known as fragment-based ligand discovery, which uses candidate ligand molecules about half the size of the small molecules in pill-based drugs. (innovationtoronto.com)
The team also demonstrated that some of the protein-binding ligand molecules identified with the system have strong biological activity-and thus have the potential to be developed into scientific probes or drugs. (innovationtoronto.com)

Eloxx's lead investigational product candidate, ELX-02, is a small molecule drug candidate designed to restore production of full-length functional proteins. (yahoo.com)
The goal of this RFA is to stimulate the development of a new generation of methods for natural products chemistry, and in doing so, to reinvigorate the investigation of nature as a prolific source of small-molecules with the potential to interact with all of the proteins that participate in cellular processes in health and disease. (nih.gov)
Small-molecule medications that selectively eliminate RNAs encoding disease-causing proteins by bringing them close to nucleases make up this new family of targeted RNA degraders. (medgadget.com)
Ion channels are integral membrane proteins found in all cells that mediate the selective passage of specific ions or molecules across a cell membrane. (caltech.edu)
Identify small molecule precursors, proteins, or bioactive molecules to activate the silenced paternal Ube3a. (cureangelman.org)
Researchers have long sought better ways to identify small-molecule ligands for human proteins and to determine which proteins in our cells are inherently "ligandable. (innovationtoronto.com)
Biologists typically have used complex computer algorithms to predict whether a given class of proteins can bind adequately to small molecules. (innovationtoronto.com)
Pharmaceutical researchers often won't even try to develop drugs to target proteins that are thought unligandable. (innovationtoronto.com)
Cravatt's team attached candidate fragment molecules to a class of other molecules that, when they can get close enough, react strongly with cysteine amino-acids on proteins, locking the ligands to the proteins with strong "covalent" bonds. (innovationtoronto.com)
The scientists devised a screening system in which they can apply these covalent-bonding fragment molecules one by one to entire collections of proteins expressed in human cells. (innovationtoronto.com)
The system allows researchers to detect and identify which small-molecule fragments have bound covalently to which proteins in the samples and which specific sites on the proteins are responsible for binding. (innovationtoronto.com)
Applying a small library of cysteine-reactive fragments to the proteins found in two types of human cancer cells, the scientists found that the fragments successfully "liganded" more than 750 different cysteines found on more than 600 distinct proteins-which equated to more than 20 percent of all the proteins assayed in the samples. (innovationtoronto.com)
In fact, about 85 percent of the newly liganded proteins are not listed in a standard database of proteins with known small-molecule ligands. (innovationtoronto.com)
CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules. (cdc.gov)

Eloxx Pharmaceuticals, Inc. is engaged in the science of ribosome modulation, leveraging its innovative TURBO-ZM™ chemistry technology platform in an effort to develop novel Ribosome Modulating Agents (RMAs) and its library of Eukaryotic Ribosome Selective Glycosides (ERSGs). (yahoo.com)
WATERTOWN, Mass., Sept. 08, 2021 (GLOBE NEWSWIRE) -- Eloxx Pharmaceuticals (Nasdaq: ELOX), today announced the appointment of Ali Hariri, M.D., as its Chief Medical Officer, overseeing clinical development efforts for the company's promising pipeline of therapies to treat rare diseases. (biospace.com)
WATERTOWN, Mass., Sept. 18, 2023 (GLOBE NEWSWIRE) -- Eloxx Pharmaceuticals, Inc. (NASDAQ: ELOX), a leader in ribosomal RNA-targeted genetic therapies for rare diseases, today reported additional independent confirmation on the positive TEM assessment results from its proof-of-concept Phase 2 open-label clinical trial ( NCT05448755 ) of ELX-02 for the treatment of Alport syndrome after eight weeks of treatment. (ozarksfirst.com)
WATERTOWN, Mass., June 21, 2023 (GLOBE NEWSWIRE) - Eloxx Pharmaceuticals, Inc. (NASDAQ: ELOX), a leader in ribosomal RNA-targeted genetic therapies for rare diseases, today announced that it will host an Investor and Analyst call and webcast on Tuesday, June 27, 2023 at 11:30 am ET. (itbusinessnet.com)

This will be made possible in part through access to an exceptional collection of small molecules. (worldpharmanews.com)

DNA-encoded small molecule libraries (DELs) created using combinatorial chemistry and synthetic oligonucleotides are being successfully applied to drug discovery projects across the pharmaceutical industry. (x-chemrx.com)

A focused medicinal chemistry campaign will identify small-molecule hits, and Absorption, Distribution, Metabolism and Excretion (ADME), pharmacokinetic/pharmacodynamic (PK/PD), potency and safety of these therapeutic candidates will be assessed in vitro and in animal models. (europa.eu)
The oncology-focused collaboration will leverage Bayer's small molecule compound library and expertise in biology and medicinal chemistry as well as Recursion's purpose-built artificial intelligence-guided drug discovery platform. (worldpharmanews.com)

Ultra-Glo was derived by directed evolution and is the key component in Kinase-Glo Assay and a suite of other bioluminescent assays for high throughput screening and profiling of small molecule compound libraries. (wtnnews.com)
Usually, access to these compound libraries is highly restricted. (worldpharmanews.com)
Its faculty and staff can help researchers develop appropriate assays, screen targets against the facility's diverse compound libraries, analyze and interpret assay results, and identify potential hits. (umaryland.edu)
Several contributors argued that any granting of access to compound libraries should be on a strictly voluntary basis. (who.int)

The methodology in which Recursion uses artificial intelligence (AI) in drug discovery, could be one of the most disruptive technologies of our time," said Juergen Eckhardt, M.D., Member of the Executive Committee of Bayer's Pharmaceuticals Division, Head of Business Development, Licensing & Open Innovation and Head of Leaps by Bayer. (worldpharmanews.com)

The ability to rapidly identify small molecules that non-covalently bind to a specific target is a critical tool that will benefit many promising therapeutic targets. (ddw-online.com)
Chengdu, China，November 23rd 2017, HitGen Ltd announced that the company has entered into a drug discovery research collaboration with Boehringer Ingelheim to identify novel small molecule leads for targets of interest to Boehringer Ingelheim. (hitgen.com)

Pharmaceutical nitroxide drug candidates for treatment and/or prevention of aging-related and smoking-related diseases are in various different stages of development. (frontiersin.org)
A key challenge is the poor solubility and bioavailability of many small-molecule drug candidates, often leading to poor absorption of the drug in the gastrointestinal tract. (chemistryworld.com)
Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. (vcnewsdaily.com)

Large pharmaceutical companies join forces with small and medium-sized enterprises (SMEs) and academia in an IMI-supported public private partnership (PPP) to enhance early drug discovery and so address the ever-increasing need for innovative therapeutics to tackle unmet medical needs. (worldpharmanews.com)
Prof. Eric Haaksma, Senior Vice President Research Germany, said "We are very excited about the opportunity to complement our in-house expertise in the field of small molecule therapeutics research with HitGen's DNA encoded library platform. (hitgen.com)
HitGen is working with multiple pharmaceutical, biotech companies and research institutes to discover and develop novel therapeutics of the future. (hitgen.com)

Of 14,400 candidates screened from a library of existing chemicals, SAFIRE identified 70 that hold promise. (sciencedaily.com)
Product candidates selected and developed from proprietary library of approximately 750 small molecule neuropeptide analogues with broad utility. (dmkpharmaceuticals.com)

Because the biotin label is stable and small, it rarely interferes with the function of labeled molecules enabling the Avidin-biotin interaction to be used for the development of robust and highly sensitive assays. (genomicglossaries.com)
To achieve this, a collection of repurposed drugs, focused libraries and small molecule libraries will be screened against SARS-CoV-2, other emerging SARS-CoV-2 clades and related coronavirus genera in phenotypic or target-based assays. (europa.eu)
Historically, binding assays have relied on displacement formats utilising fluorescent and radioactive probes 1,2 that required synthesising specific probes, thereby limiting the approach to identifying competitive molecules. (ddw-online.com)
Unlike many indirect binding assays, a major advantage of detecting the mass ID of a binding molecule is that multiple molecules can be tested simultaneously. (ddw-online.com)
CRISPR-based peptide library display and programmable microarray self-assembly for rapid quantitative protein binding assays. (cdc.gov)

FDA and Near-FDA Approved Drugs -Identify pharmaceuticals that are, or are in the process of being, FDA approved. (cureangelman.org)

The small absorption imprint in the emerging, multiply scattered, diffuse light can be detected sensitively by the use of wavelength modulation techniques, easily achievable using diode laser spectroscopy. (lu.se)

Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients by tackling key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. (vcnewsdaily.com)
There have been many recent advances in DEL technology with the promise of helping to deliver ever more efficacious and beneficial small molecule-based tools and therapies. (x-chemrx.com)

Since the introduction of the technique, DNA shuffling has been applied to protein and small molecule pharmaceuticals, bioremediation, vaccines, gene therapy, and evolved viruses. (wikipedia.org)
We will share positive results to further expedite the discovery and validation by enabling concurrent evaluation of like drug/protein structures and families of small molecule precursors by multiple research groups. (cureangelman.org)

Bayer and US-based Recursion Pharmaceuticals, Inc., a clinical stage TechBio company decoding biology to industrialize drug discovery, announced that they have updated the focus of their research collaboration to precision oncology. (worldpharmanews.com)

Additionally, it is anticipated that increased demand for small molecule pharmaceuticals or other small molecules would accelerate market expansion. (medgadget.com)
We have employed a collaborative approach with different, yet complimentary, drug libraries and reporter / detection strategies to accelerate discovery. (cureangelman.org)

Any of these could alter the action of the active pharmaceutical ingredient (API), thereby reducing its potency, or lead to the formation of toxic degradation products, which could give rise to adverse effects. (pittcon.org)
Organisations are outsourcing their active pharmaceutical ingredient (API) manufacture more often than ever before, so selecting a contract manufacturing organisation (CMO) is of increasing importance. (almacgroup.com)

Nitroxide small molecule agents are in development as preventative or therapeutic pharmaceutical drugs for age-related macular degeneration (AMD) and cardiovascular disease, which are two major diseases of aging. (frontiersin.org)
therefore, it´s necessary to search for therapeutic alternatives derived from natural products, based on the study of medicinal plants as a source of molecules with highly effective leishmanicidal potential. (jppres.com)
We hope to give ourselves a better chance of finding the really critical point to intervene," adds Dr Weir, who explains that it is still a lot to ask from a molecule to interact with one drug target and to have a significant therapeutic effect. (pmlive.com)

We have seen patients become more empowered in the pharmaceutical industry in recent years. (chemistryworld.com)

[1] (online, 7 November 2016), the researchers say their results demonstrate the potential for bacterial-derived small molecules to act as antigens in vaccines. (pharmaceutical-journal.com)

ESCAR has a design of two acceptor chambers representing the blood uptake pathway and the lymphatic uptake pathway, respectively, although only the blood uptake pathway was investigated for small molecules in this study. (ku.edu)

at Stephen B. Thacker CDC Library on March 27, 2015 reactions in the lung are life threatening. (cdc.gov)

We are pleased to establish a collaboration with Sun Pharma, a leading global pharmaceutical company, in the onco-dermatology space. (tmcnet.com)
We are delighted to enter this collaboration with Boehringer Ingelheim, a major research based pharmaceutical company providing world-wide benefits to patients This collaboration further emphasizes the role of HitGen in the rapidly developing field of DNA-encoded chemistry. (hitgen.com)
Another application area is the pharmaceutical one, which is explored in collaboration with the Astra Zeneca. (lu.se)

This update is also a momentous event for Eloxx, as ZKN-013, our lead TURBO-ZM™ based molecule, is the first program developed from hit to lead and is now poised to enter clinical development. (yahoo.com)
Before joining Sanofi, Dr. Hariri held clinical development roles at Ionis Pharmaceuticals and Takeda and was a practicing nephrologist. (biospace.com)
Stability testing is one of the most important steps during the development of a pharmaceutical product. (pittcon.org)
It is important for pharmaceutical companies to have the necessary analytical methodologies in place early in the development process so potential impurities are identified early on and are not a surprise at the time approval is sought. (pittcon.org)
By placing the needs of the patient at the forefront of drug development, pharmaceutical companies can formulate drugs that patients are happy to take and lower the patients' pill burden, maximising the overall health, quality of life, and cost benefit of the drug. (chemistryworld.com)
Every cancer is different and requires an individual approach," said Dominik Ruettinger, M.D., Ph.D., Global Head of Research and Early Development for Oncology, Pharmaceuticals Division, Bayer AG. (worldpharmanews.com)
The expansion of the worldwide small molecule drug discovery market, however, is anticipated to be constrained by factors such the high cost of drug development and rigorous regulations. (medgadget.com)
For instance, the Indian pharmaceutical sector is attempting to climb the global pharmaceutical value chain by investing in R&D for medication development, according to the India Brand Equity Foundation (IBEF). (medgadget.com)
Over the course of the forecast period, an increase in research and development efforts by industry participants is anticipated to boost market expansion for small molecule drug discovery. (medgadget.com)
The worldwide small molecule drug discovery market is anticipated to provide attractive development prospects due to the increase in demand for small molecule medications. (medgadget.com)
Players in the small molecule drug discovery market should see considerable growth prospects as the number of contract research and development firms grows. (medgadget.com)
Providing services for all stages of drug development for small (including highly potent) molecules and peptides. (almacgroup.com)
Almac Sciences provides integrated services from development to commercial scale of advanced intermediates and Active Pharmaceutical Ingredients (API). (almacgroup.com)
DMK Pharmaceuticals is a clinical stage neuro-biotechnology company focused on the development and commercialization of potential blockbuster products for the treatment of a variety of neuro-based disorders with significant unmet medical needs. (dmkpharmaceuticals.com)
He has over two years of process experience in industry working on the development of innovative synthetic methods and synthesis of complex molecules. (burnslev.com)
His graduate studies at the University of Connecticut involved method development and new reaction discovery in the synthesis of natural product-like molecules. (burnslev.com)
The lab features top-notch expertise and resources for pharmaceutical pre-formulation, formulation development, analytical methods development, and testing. (umaryland.edu)
On the Development of a Robust and Transferable Tandem Mass Spectral Library for the Identification of Small Bioorganic Molecules. (go-jsb.nl)
With respect to promoting research and development (Element 2), concern was expressed about an open-source model for research and development of pharmaceutical products. (who.int)

The market for small molecule drug discovery was estimated at US$ 43,571.6 Mn in 2021 and is anticipated to grow at a CAGR of 8.1% from 2022 to 2028 to reach US$ 74,672.5 Mn. (medgadget.com)
Chemical & pharmaceutical bulletin 2021 0 0. (cdc.gov)

His work involves patent prosecution in the Life Sciences, including biotechnology and pharmaceuticals, small molecules, and chemistry. (burnslev.com)

His work included phosphine-mediated cycloisomerization of alkynyl hemiketals, the rearrangement of spiroketals, and small library synthesis/SAR studies of desoamine analogs. (burnslev.com)

Game-changing new technologies are propelling the pharmaceutical industry forward and inspiring a new wave of patient-centric medicines. (chemistryworld.com)

Sun Pharma is the world's fourth largest specialty generic pharmaceutical company and India's top pharmaceutical company. (tmcnet.com)
Quantum Pharmaceuticals is issuing the commercial release of research software that is expected to speed up pharma R&D and change the drug discovery software market. (technologynetworks.com)
For instance, in August 2022, BioDuro-Sundia and X-Chem announced jointly that DNA Encoded Compound Library (DEL) technology services will be made available in China to assist global pharma firms in finding new small molecule medications more swiftly. (medgadget.com)

I want to get the latest chemistry news from C&EN in my inbox every week. (acs.org)

To feed the pipeline, Detweiler's lab developed a technique called SAFIRE for screening for new small molecules which work differently than older drugs. (sciencedaily.com)
We are very pleased to have secured this Series C funding from an outstanding group of life science investors who recognize the potential of our clinical-stage pipeline of unique switch control kinase inhibitors,' said Michael D. Taylor, Ph.D., President and CEO of Deciphera Pharmaceuticals. (vcnewsdaily.com)

However, due to its merits, the guidance released by the U.S. Food and Drug Administration (FDA) in 2004 included the application of continuous manufacturing to pharmaceuticals, and in 2015 the use of drugs manufactured in continuous manufacturing. (yokogawa.com)

The stability of a pharmaceutical product has been defined as the capability of a particular formulation in a specific packaging system to remain within its physical, chemical, microbiological, toxicological, protective and informational specifications. (pittcon.org)
The research, conducted by the NIH Chemical Genomics Center (NCGC), describes Ultra-Glo recombinant luciferase as approximately 90% less susceptible to small molecule inhibition compared to another commercially available luciferase. (wtnnews.com)
Our data suggest that the human proteome is much more broadly targetable with small molecules than has been previously appreciated," said principal investigator Benjamin F. Cravatt, chair of the Department of Chemical Physiology and member of the Dorris Neuroscience Center and Skaggs Institute for Chemical Biology at TSRI. (innovationtoronto.com)
Participants will gain a deep understanding on the use of supercritical fluids in different processes such as extraction and chromatography, material/polymer design, pharmaceutical drug formulation, crystallisation, chemical reactions and biocatalysis. (lu.se)

The second column dissociates the complex prior to MS detection of the small molecule using an electrospray ionisation (ESI) source. (ddw-online.com)

There is increasing demand from both pharmaceutical companies and regulatory bodies for increasingly sensitive analytical techniques that can provide the highest possible assurance that a product is of acceptable quality and will provide the promised efficacy safely. (pittcon.org)
The worldwide small molecule drug discovery market is anticipated to develop as small molecule medications receive more regulatory approval. (medgadget.com)
Continuous manufacturing has already been introduced in fields such as petrochemicals and food, but progress has been slow in the pharmaceutical industry due to regulatory constraints. (yokogawa.com)

We offer a full suite of analytical testing for a range of different product types including small molecules, peptides, biologics, conjugates, potent and controlled substances. (almacgroup.com)

Five centers and three facilities at the University of Maryland School of Pharmacy operate within the Department of Pharmaceutical Sciences (PSC). (umaryland.edu)

Due to the rising illness burden and expanding elderly population throughout the world, the worldwide small molecule drug discovery industry is expanding rapidly. (medgadget.com)

As a pharmaceutical company, there are many ways to add value and drive patient centricity in the industry. (chemistryworld.com)
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. (eloxxpharma.com)
See the definitions of "large accelerated filer," "accelerated filer," "smaller reporting company," and "emerging growth company" in Rule 12b-2 of the Exchange Act. (eloxxpharma.com)

The Quantum software was applied in different in-house and collaborative drug discovery projects of Quantum Pharmaceuticals. (technologynetworks.com)
Big pharmaceutical companies are working with both kinds of AI-based partners as they endeavor to keep pace with the fast-evolving engine for data-driven drug discovery. (acs.org)
The technology has also made stealth advances in industry, including the pharmaceutical industry, in which not very long ago researchers questioned its role and expressed concerns over machines taking their jobs in drug discovery labs. (acs.org)
The market for small molecule drug discovery is divided into five regions based on geography: North America, Latin America, Europe, Asia Pacific, and the Middle East & Africa. (medgadget.com)
In addition, due to greater investments in drug discovery, Asia Pacific is anticipated to have strong growth in the global small molecule drug discovery market. (medgadget.com)
This partnership, the first of its kind, is supported by the Innovative Medicines Initiative (IMI) and creates unprecedented opportunities for the discovery of new medicines by providing public partners with an 'industry-like' discovery platform to translate cutting-edge academic research into high-quality drug lead molecules on a scale and speed that was not possible previously. (worldpharmanews.com)

The goal of the pharmaceutical industry should be to drive this further and implement patient centricity on a more global scale. (chemistryworld.com)
We contribute with +30 years of combined experiences from the pharmaceutical industry. (lu.se)
In this interview, we learn more about her research, how she has simultaneously juggled doing a Ph.D. while working in the pharmaceutical industry, and what she enjoyed most during her time in academia. (lu.se)

The first column isolates the small molecule-target complex. (ddw-online.com)

In recent research, a team from the University of Michigan developed a vaccine using siderophores - small molecules secreted by E. coli that are critical for the establishment of a UTI and help the bacteria capture iron from the host. (pharmaceutical-journal.com)
Most antibiotics in use today were developed in the 1950s, and pharmaceutical companies have since scaled back on research in the field in favor of more profitable ventures. (sciencedaily.com)
The EU-funded CARE project is a coalition of 37 academic institutions, pharmaceutical companies and non-profit research organisations. (europa.eu)
Of this, €80 million comes from the European Commission's Seventh Framework Programme for Research (FP7), and €91 million is provided as in kind contributions from the participating companies that are members of the European Federation of Pharmaceutical Industries and Associations (EFPIA). (worldpharmanews.com)
This research was catalyzed by the solving of atomic resolution crystal structures of the mechanosensitive channels of large and small conductance (MscL and MscS) by the Rees group. (caltech.edu)
Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. (mdpi.com)

Biotin-binding to streptavidin and avidin is resistant to extremes of heat, pH and proteolysis, making capture of biotinylated molecules possible in a wide variety of environments. (genomicglossaries.com)

As genetics has taken its place on the forefront of scientific technology, this new finding proves especially significant: it is these molecules that allow the information stored on the DNA strands to be translated for use within an organism. (cornellsun.com)
You've got some part of the scientific community that's fascinated by a molecule and fascinated by technology," he explains. (pmlive.com)

It is a reliable tool for the identification of small molecules. (go-jsb.nl)

For soft matter, small-angle scattering is an ideal technique to study structures in the nanometre to micrometre range and get information on the inner structure of disordered or partially ordered materials that are difficult to crystallise. (lu.se)

Chemicals and Drugs4

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Phenomena and Processes4

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Information Science5

Compounds18

Ligand5

Proteins14

Eloxx Pharmaceuticals4

Collection of small molecules1

DELs1

Medicinal chemistry2

Compound libraries4

Bayer's1

Targets2

Drug candidates3

Therapeutics3

Candidates2

Assays5

Identify1

Absorption1

Therapies2

Protein2

Recursion Pharmaceuticals1

Accelerate2

Active pharmaceut2

Therapeutic3

Empowered in the pharmaceutical industry1

Vaccines1

Pathway1

Thacker CDC Library1

Collaboration3

Development19

20212

Biotechnology1

Synthesis1

Propelling the pharmaceutical industry1

Pharma3

Chemistry1

Pipeline2

Drugs1

Chemical4

Detection1

Regulatory3

Analytical1

Sciences1

Rapidly1

Company3

Discovery6

Industry3

Complex1

Research6

Environments1

Technology2

Identification1

Structures1