• intervention
  • C. W. Hoedemaekers, M. Ezzahti, A. Gerritsen, and J. G. van der Hoeven, "Comparison of cooling methods to induce and maintain normo- and hypothermia in intensive care unit patients: a prospective intervention study," Critical Care , vol. 11, p. (hindawi.com)
  • Intrapartum
  • After regression analysis, other identified perinatal risk factors (n=619) included hypertension in pregnancy (aOR 3.77), male infant (aOR 2.51), non-cephalic presentation (aOR 5.74), lack of fetal monitoring (aOR 2.75), augmentation (aOR 2.23), obstructed labour (aOR 3.8) and an acute intrapartum event (aOR 8.74). (bmj.com)
  • cardiac
  • 4 Since then, induction of hypothermia after return of spontaneous circulation (ROSC) has been associated with improved functional recovery and reduced cerebral histological deficits in various animal models of cardiac arrest. (ahajournals.org)
  • normothermia
  • In the European study, the median Glasgow Coma Scale score on hospital admission in both groups was 3 with an interquartile range of 3 to 5 in the group with normothermia and 3 to 4 in the group with hypothermia. (ahajournals.org)
  • In the European study, 75 of the 136 patients (55%) in the hypothermia group for whom data were available had a favorable neurological outcome (able to live independently and work at least part-time) at 6 months compared with 54 of 137 (39%) in the normothermia group (relative risk [RR] 1.40, 95% CI 1.08 to 1.81, number needed to treat [NNT]= (ahajournals.org)
  • 19 At 6 months there were 56 deaths in the 137 participants (41%) in the hypothermia group versus 76 of 138 (55%) in the normothermia group (RR 0.74, 95% CI 0.58 to 0.95, NNT=7). (ahajournals.org)
  • Brain
  • Conclusions Perinatal infection and inflammation are independent risk factors for NE in this low-resource setting, supporting a role in the aetiological pathway of term brain injury. (bmj.com)