• molecule
  • It is concluded that the acetyl groups in the 60 per cent active acetyl pepsin, which are responsible for the decrease in specific enzymatic activity, are 3 in number and are attached to 3 tyrosine phenol groups of the pepsin molecule. (rupress.org)
  • amino acids
  • Pepsin is most efficient in cleaving peptide bonds between hydrophobic and preferably aromatic amino acids such as phenylalanine, tryptophan, and tyrosine. (wikipedia.org)
  • Pepsin will digest up to 20% of ingested amide bonds by cleaving preferentially at the N-terminal side of aromatic amino acids such as phenylalanine, tryptophan, and tyrosine. (wikipedia.org)
  • acid reflux
  • At the mean pH of the laryngopharynx (pH = 6.8) pepsin would be inactive but could be reactivated upon subsequent acid reflux events resulting in damage to local tissues. (wikipedia.org)
  • While enzymatically inactive in this environment, pepsin would remain stable and could be reactivated upon subsequent acid reflux events. (wikipedia.org)
  • chymosin
  • If rennet is extracted from older calves (grass-fed or grain-fed), the rennet contains less or no chymosin, but a high level of pepsin and can only be used for special types of milk and cheeses. (wikipedia.org)
  • Food
  • Omaha, NE ( SafetyAlerts ) - The Food and Drug Administration (FDA) said that American Laboratories Incorporated has recalled Bulk Pepsin 1:10,000 NF XII Powder in 110-lb. drums or varying sizes per customer need. (safetyalerts.com)
  • organic
  • His many contributions to biology include the development of cell theory, the discovery of Schwann cells in the peripheral nervous system, the discovery and study of pepsin, the discovery of the organic nature of yeast, and the invention of the term metabolism. (wikipedia.org)
  • inactive
  • Pepsin exhibits maximal activity at pH 2.0 and is inactive at pH 6.5 and above, however pepsin is not fully denatured or irreversibly inactivated until pH 8.0. (wikipedia.org)
  • mechanism
  • Bovine uterine serpin does inhibit pepsin but probably through a mechanism distinct from the prototypical mechanism used by serpins. (wikipedia.org)
  • conditions
  • The phenol group of glycyl tyrosine is acetylated by ketene under the conditions used in the acetylation of pepsin and the effect of pH on the rate of acetylation is similar in the two cases. (rupress.org)
  • Under non-acid conditions (neutral pH), pepsin is internalized by cells of the upper airways such as the larynx and hypopharynx by a process known as receptor-mediated endocytosis. (wikipedia.org)
  • active site
  • The propeptide contains two helices that block the active site cleft, in particular the conserved Asp11 residue, in pepsin, hydrogen bonds to a conserved Arg residue in the propeptide. (wikipedia.org)
  • known
  • Based on the book, it can be assumed that the first known exoenzymes were pepsin and trypsin, as both are mentioned by Vernon to have been discovered by scientists Briike and Kiihne before 1908. (wikipedia.org)
  • high
  • The stability of pepsin at high pH has significant implications on disease attributed to laryngopharyngeal reflux. (wikipedia.org)
  • found
  • They found that neither Pepsi Cola nor Coca-Cola had any narcotics, alcohol, or Pepsin present in them. (wikipedia.org)
  • less
  • The tyrosine-tryptophane content of this acetylated pepsin, measured colorimetrically, is less than pepsin by three tyrosine equivalents. (rupress.org)
  • health
  • Based on the information provided by the Ministry of Public Health that assured the Department of Fatwas of the lack of narcotics, alcohol, pepsin, and microbes in both Pepsi Cola and Coca-Cola, Hasanayn al-Makhluf declared the drinks to be permissible under Islamic law. (wikipedia.org)