• study
  • In one study the age-related penetrance of MEN1 was 7% by age 10 but nearly 100% by age 60. (wikipedia.org)
  • PARTICIPANTS: For this study, the penetrance of the variant rs74315329 was estimated in 2 population-based cohorts, the TwinsUK (N = 6092) and the Rotterdam Study (RS) (N =11 189). (ru.nl)
  • RESULTS: In our study, the observed penetrance of the variant rs74315329 in relation to increased IOP was 12.5% and 19.4% in the TwinsUK and the RS, respectively. (ru.nl)
  • It should be noted that the 96% penetrance figure comes from one study. (wikipedia.org)
  • risk
  • MAIN OUTCOME MEASURES: The penetrance of the variant rs74315329 was estimated from the percentage of the carriers of the risk allele of the variant who had high IOP (ocular hypertension) or glaucoma. (ru.nl)
  • birth
  • Our data indicate that Df1 /+ embryos are able to overcome a localized arterial growth impairment and thereby reduce the penetrance of birth defects. (oup.com)