• Mox2
  • Associated Genetic Factors: PAX3, c-Met, Mox2, MSX1, Six, Myf5, and MyoD Mox2 (also referred to as MEOX-2) plays an important role in the induction of mesoderm and regional specification. (wikipedia.org)
  • bone morphoge
  • Examples of such proteins include bone morphogenetic proteins and cadherins. (wikipedia.org)
  • Current studies have raised several important questions, including whether a condensed CNS has arisen only once or multiple times during evolution and whether patterning of the CNS by bone morphogenetic proteins (BMPs) in different branches of the phylogenetic tree reflects a conserved ancestral mechanism (homology) or parallel evolution (convergent evolution). (pubmedcentralcanada.ca)
  • dorsal
  • however, it impairs the correct activation of transcription factors involved in the epithelial-mesenchymal transition (EMT) and reduces the extent of NC cell migration, which leads to a decrease in NC-derived craniofacial skeleton, melanocytes and dorsal fin structures. (biologists.org)
  • repressor
  • One of the principal differences between HTH motifs in these different proteins arises from the stereo-chemical requirement for glycine in the turn which is needed to avoid steric interference of the beta-carbon with the main chain: for cro and repressor proteins the glycine appears to be mandatory, whereas for many of the homeotic and other DNA-binding proteins the requirement is relaxed. (wikipedia.org)
  • lateral
  • J:84706 Assimacopoulos S, Grove EA, Ragsdale CW, Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex. (jax.org)
  • development
  • These consequences further reveal the complexity of myogenesis and the importance of each genetic factor in proper muscle development. (wikipedia.org)
  • Studies in Xenopus laevis have greatly contributed to understanding the roles that the Zic family of zinc finger transcription factors play as essential drivers of early development. (springer.com)
  • These findings strongly support a role for MSX and DLX in contributing to spatiotemporal regulation of GnRH transcription during development. (pubmedcentralcanada.ca)
  • family
  • Other proteins in the family, such as NANOG are involved in maintaining pluripotency. (wikipedia.org)
  • There is a linkage found between TNS and markers surrounding the MSX1 locus and it showed that a nonsense mutation (S202X) in MSX1 cosegregated with the TNS phenotype in a three-generation family. (wikipedia.org)
  • essential
  • Work from many laboratories, including our own, has shown that Wnt proteins are essential for the control over stem cells. (stanford.edu)
  • form
  • Glycosaminoglycans (GAGs), such as DS, chondroitin sulfate (CS) and heparan sulfate (HS), are side chains of repeating disaccharides, which are covalently attached to distinct core proteins in the Golgi complex to form cell surface and extracellular matrix proteoglycans (PGs) ( Iozzo and Schaefer, 2015 ). (biologists.org)
  • cells
  • If placed in cell culture, most myoblasts will proliferate if enough fibroblast growth factor (FGF) or another growth factor is present in the medium surrounding the cells. (wikipedia.org)
  • MSX1 transcripts are not only found in thyrotrope-derived TSH cells, but also in the TtT97 thyrotropic tumor, which is a well differentiated hyperplastic tissue that produces both TSHß- and a-subunits and is responsive to thyroid hormone. (wikipedia.org)