OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation Science
GlycopeptidesOligosaccharidesCarbohydrate ConformationMannosePronaseCarbohydrate SequenceFucoseTeicoplaninCarbohydratesGlycoproteinsGlycosylationPolysaccharidesAsparagineSialic AcidsGlucosamineVancomycinChromatography, GelNeuraminic AcidsAmino SugarsGlycoside HydrolasesGalactoseAcetylgalactosamineLectinsMucinsChromatography, AffinityAnti-Bacterial AgentsMannosidasesMolecular Sequence DataPlant LectinsAcetylglucosamineAcetylglucosaminidaseOvomucinPeptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine AmidaseMannosyl-Glycoprotein Endo-beta-N-AcetylglucosaminidaseAmino AcidsAmino Acid SequenceFetuinsChromatography, High Pressure LiquidConcanavalin ACarbon-Oxygen LigasesHexosaminesTrypsinHexosesEnterococcusMass SpectrometryStaphylococcus haemolyticusPeriodic AcidMolecular WeightMannosidesMonosaccharidesMicrobial Sensitivity TestsHexosaminidasesGram-Positive Bacterial Infectionsalpha-MannosidaseGlycomicsVancomycin ResistanceChemistryN-Acetylneuraminic AcidGlycosidesChromatography, PaperChemical PhenomenaAntigens, Tumor-Associated, CarbohydrateStaphylococcal InfectionsMucin-1NeuraminidaseAsialoglycoproteinsHydroxylysineSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationChromatography, Ion ExchangeStaphylococcus aureusTandem Mass SpectrometryGalactose OxidaseAcetamidesMagnetic Resonance SpectroscopyMNSs Blood-Group SystemEnterococcus faeciumSuccinic AnhydridesOxazolidinonesMethicillin Resistancealpha-L-FucosidasePeptide FragmentsSulfuric AcidsGalactosamineAntifreeze ProteinsBlood Group AntigensGram-Positive BacteriaDrug Resistance, MicrobialCattlealpha-Fetoproteins
AntibioticAntibioticsTeicoplaninStaphylococcusAminoglycosidesBactericidalAureusResistanceCross-reactivityCharacterization2020MRSAAntibodiesBeta-lactamsIsolatesCritically ill patientsMultiple sclerosisInfectionsGLYCOPROTEINSPediatricVitroIsolated from hospitalized patientsPenicillinAllergicOutcomesDiagnosisMultidrugEnterococcusMolecularIntensive careSepsisInfectionAbundancePOPULATIONSDetectionInhibitsAssaysAdverseMortalityBacteremiaTreatmentUrine of patientsAdult patientsClassificationPrimarilyImmuneVancomycin-associated2001DalbavancinSyntheticConclusionsStudyEndocarditisComorbidities
Antibiotic11
  • Antibiotic-sensitivity was determined for 323 enterococci strains originating from hospitalized and ambulatory patients. (medscimonit.com)
  • This approval aligns the dosing regimen with the U.S. label, but more importantly, it could enhance the convenience of antibiotic administration for both healthcare providers and their patients. (prnewswire.com)
  • It is a good alternative antibiotic for patients allergic to or intolerant of the macrolide class. (medscape.com)
  • Vancomycin is a glycopeptide antibiotic used against multi-drug resistant gram-positive bacteria such as Staphylococcus aureus (MRSA). (nih.gov)
  • Glycopeptide antibiotic complex from Actinoplanes teichomyceticus active against gram-positive bacteria . (lookformedical.com)
  • In conclusion, we demonstrated the emergence and spreading of a new isolate of MRSA in CF patients in Marseille, France, that has probably been selected in the airways by antibiotic pressure. (biomedcentral.com)
  • Vancomycin is a glycopeptide antibiotic that is used to treat certain infections caused by methicillin-resistant Staphylococcus aureus, such as skin infections, sepsis, endocarditis, bone & joint infections, and meningitis. (factmr.com)
  • It's a glycopeptide antibiotic that works by inhibiting cell walls from forming. (factmr.com)
  • A large literature supports that early identification of sepsis, early source control and early antibiotic treatment are critical to save lives of patients with sepsis and septic shock (Evans et al. (csccm.org.cn)
  • Vancomycin is a glycopeptide antibiotic considered the gold standard in the treatment of staphylococcal infections that are oxacillin-resistant. (bvsalud.org)
  • Vancomycin is a glycopeptide antibiotic first isolated in 1953. (medscape.com)
Antibiotics10
  • It is derived from a complex of glycopeptide antibiotics, referred to as A-40926, that is produced by a new strain of Actinomadura. (wikipedia.org)
  • All the enterococci strains were sensitive to glycopeptide antibiotics: vancomycin, teicoplanin. (medscimonit.com)
  • Do not administer cholera vaccine to patients who have received oral or parenteral antibiotics within 14 days prior to vaccination. (medscape.com)
  • Particular groups of patients, including those with cystic fibrosis , immune dysfunction, and certain chronic infectious disease, are more likely to be treated with this class of antibiotics. (medscape.com)
  • The use of drugs is a modifiable risk factor for AKI, accounting for about 20%-40% of AKI in critically ill patients, and antibiotics are the key trigger of AKI in all drugs ( Morales-Alvarez, 2020 ). (frontiersin.org)
  • Objective: The indiscriminate use of antibiotics has led to the creation of resistant microorganisms, with the aim of this study was to compare in vitro the degree of effectiveness of beta-lactam antibiotics and glycopeptide in the inhibition of Staphylococcus aureus by comparing its effectiveness in surgical wound infection. (bvsalud.org)
  • Moreover this phage could be seen by electron microscopy when mobilized with several antibiotics commonly used in CF patients including, tobramycin, ciprofloxacin, cotrimoxazole, or imipenem. (biomedcentral.com)
  • People who treated with these antibiotics for long periods, those with a history of hospitalization or surgical procedures, patients with indwelling medical devices, immunocompromised patients, and those with underlying diseases are at higher risk of infections with MDR-Enterococci. (biomedcentral.com)
  • Region ( 2-4 ).This practice more often causes increased vary in older patients and those having comorbidities, tolerance to antibiotics and other subsequent health is- especially cardiac issues. (who.int)
  • Vancomycin injection is in a class of medications called glycopeptide antibiotics. (medlineplus.gov)
Teicoplanin9
Staphylococcus9
Aminoglycosides2
Bactericidal2
  • To date, bactericidal activity has been regarded as a desirable characteristic in antimicrobial agents when treating patients with endocarditis, while, routine MBC testing is not recommended because of the technical difficulties associated with these tests [ 11 - 15 ]. (biomedcentral.com)
  • Biofilm, glycopeptide non permeability , ph lowering sec to lactic acidosis ,bactericidal failure switching to bacteriostatic status quo etc. (jwatch.org)
Aureus4
  • Sensitivity of S. aureus to beta-lactam and glycopeptide. (bvsalud.org)
  • Recent reports show that the prevalence of Methicillin-Resistant S. aureus (MRSA) infections in cystic fibrosis (CF) patients is increasing. (biomedcentral.com)
  • We also conducted a retrospective epidemiological analysis on all S. aureus isolated from 2002 to 2007 in CF patients from our institution. (biomedcentral.com)
  • CF-Marseille is multidrug resistant, has a hetero-Glycopeptide-Intermediate resistance S. aureus phenotype, grows on Cepacia agar with intense orange pigmentation and has a thickened cell wall. (biomedcentral.com)
Resistance2
  • High- level v an A-mediated glycopeptide resistance has been described for E. gallinarum and E. casseliflavus (1-4), and v an B-mediated vancomycin resistance has been frequently described for E. faecalis and E. faeci- um . (cdc.gov)
  • The balance between an overuse leading to resistance emergence and a strategy of large coverage for patients with suspected sepsis is a daily challenge in the ICU. (csccm.org.cn)
Cross-reactivity1
Characterization2
  • For glycopeptide characterization, mass spectrometry has arisen as the go-to methodology. (news-medical.net)
  • For a more comprehensive and unbiased proteomic characterization, the Clinical Proteomic Tumor Analysis Consortium performed mass spectrometry-based proteomic and/or phosphoproteomic analyses of tumor tissues from patients with colon, breast, and ovarian cancers, which demonstrated that proteomic signatures can provide information that can further stratify patients. (genomeweb.com)
20201
  • Our study is a retrospective analysis of medical records of 724 patients who have received vancomycin therapy from 1 January 2015 through 30 September 2020. (frontiersin.org)
MRSA5
  • XYDALBA™ was approved by the EMA in February 2015 as a treatment for Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) in adults and by the U.S. Food and Drug Administration (FDA) in May 2014 for the treatment of adult patients with ABSSSI caused by susceptible Gram-positive bacteria, including MRSA. (prnewswire.com)
  • Valve replacement is indicated in this patient because of multiple causes (DBT, MRSA, etc. (jwatch.org)
  • From my very personal experience, patients with persistent MRSA bacteremia who had experienced vancomycin treatment failure would not respond to daptomycin either. (jwatch.org)
  • For these patients with persistent MRSA bacteremia, you may need to contact the lab. (jwatch.org)
  • Phylogenetic analysis of phenotypically similar h-GISA in our study also suggests that CF patients are colonized by polyclonal populations of MRSA that represents an incredible reservoir for lateral gene transfer. (biomedcentral.com)
Antibodies4
  • In this context, this work describes the synthesis of the hypoglycosylated alpha-DG mimetic glycopeptide NHAc-Gly-Pro-Thr-Val-Thr[alphaMan]-Ile-Arg-Gly-BSA (1) as a potential tool for the development of novel antibodies applicable to dystroglycanopathies diagnosis. (cnr.it)
  • Glycopeptide 1 was used for the development of polyclonal antibodies and recombinant monoclonal antibodies by Phage Display technology. (cnr.it)
  • Accordingly, polyclonal antibodies were reactive to glycopeptide 1, which enables the application of anti-glycopeptide 1 antibodies in immune reactive assays targeting hypoglycosylated alpha-DG. (cnr.it)
  • 10 kD, usually a protein or glycopeptide) that can cause production of specific IgE antibodies and typical allergic responses. (cdc.gov)
Beta-lactams2
  • Tolerance has been described for anti-staphylococcal beta-lactams but involves also glycopeptide antimicrobial agents. (biomedcentral.com)
  • [ 3 ] Vancomycin is also used in patients who are intolerant or allergic to beta-lactams. (medscape.com)
Isolates7
  • Why is the term "glycopeptide" used, instead of vancomycin, to describe the decreased susceptibility of these CoNS isolates? (cdc.gov)
  • Because of its broader scope, the term glycopeptide is used instead of vancomycin to describe these isolates. (cdc.gov)
  • All clinical isolates with decreased susceptibility to glycopeptides have been oxacillin resistant and resistant to many other commonly used therapeutic agents. (cdc.gov)
  • Like oxacillin-resistant CoNS, isolates with decreased susceptibility to glycopeptides can show heteroresistance. (cdc.gov)
  • Isolates of S. haemolyticus and S. epidermidis with decreased susceptibility to glycopeptides have been reported. (cdc.gov)
  • Not all routine susceptibility test methods can detect CoNS isolates with decreased susceptibility to glycopeptides. (cdc.gov)
  • While the homology of the isolates was low among different patients during hospitalization, identical (9%) and similar (21%) RAPD-PCR patterns were detected between pairs of isolates from each patient. (biomedcentral.com)
Critically ill patients3
  • Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections. (cdc.gov)
  • A cohort and case-control study in critically ill patients. (cdc.gov)
  • The differential diagnosis for isolated thrombocytopenia in critically ill patients is broad and includes sepsis, disseminated intravascular coagulation and thrombotic thrombocytopenic purpura and medication effects. (imedpub.com)
Multiple sclerosis2
  • Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St. (medscimonit.com)
  • And multiple sclerosis patients can see an oral therapy on the horizon. (pharmexec.com)
Infections4
  • Attributable cost of catheter-associated bloodstream infections among intensive care patients in a nonteaching hospital. (cdc.gov)
  • Comparison of Oligon catheters and chlorhexidine-impregnated sponges with standard multilumen central venous catheters for prevention of associated colonization and infections in intensive care unit patients: a multicenter, randomized, controlled study. (cdc.gov)
  • These same guidelines are recommended in endocarditis and other severe forms, and in infections in immunosuppressed patients or neonates. (epainassist.com)
  • Recommendations for preventing trans- mission of infections among chronic hemodialysis patients. (cdc.gov)
GLYCOPROTEINS3
Pediatric2
  • Pediatric Patients (less than 18 years of age): 40 mg/kg in 3 or 4 divided doses for 7 to 10 days. (nih.gov)
  • Two separate stool samples were collected from hospitalized patients in the pediatric intensive care unit at admission and discharge times. (biomedcentral.com)
Vitro1
  • In the current study we show that designer glycopeptides containing the Thomsen-Freidenreich (TF) antigen (β-Gal-[1→3]-α-GalNAc- O -serine) are immunogenic in vivo and generate TF-specific CTL capable of recognizing a variety of tumor cells in vitro including a MUC1-expressing tumor. (silverchair.com)
Isolated from hospitalized patients1
  • Enterococci strains isolated from hospitalized patients proved sensitive to ampicillin and carbapenems in 76.8%, while strains isolated from ambulatory patients were 100% sensitive to these drugs. (medscimonit.com)
Penicillin1
  • For PEPAbx and treatment of infection by susceptible B. anthracis, effective monotherapy can be accomplished with fluoroquinolones, tetracyclines, -lactams (including penicillin, amoxicillin-clavulanate, and imipenem-cilastatin), and lipopeptides or glycopeptides. (cdc.gov)
Allergic1
  • Lipoglycopeptides are contraindicated in patients who are allergic to them. (msdmanuals.com)
Outcomes9
  • Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o. (medscimonit.com)
  • A better understanding of the MM cell surface proteome could facilitate development of new directed therapies and assist in stratification and monitoring of patient outcomes. (bmj.com)
  • The aim of this study is to assess the impact of tocilizumab on clinical outcomes mainly on oxygen needs and mortality along with summarizing the available evidence regarding its efficacy in hospitalized covid-19 patients. (ospublishers.com)
  • An early combined use of tocilizumab and systemic corticosteroids may improve clinical outcomes and overall mortality in hospitalised Covid-19 patients. (ospublishers.com)
  • Several therapeutic agents have been studied to assess their efficacy in reducing mortality rates and improving outcomes in hospitalized patients [1]. (ospublishers.com)
  • The purpose of this study is to assess the effect of tocilizumab on clinical outcomes chiefly on oxygen needs and mortality along with summarizing the available evidence regarding its efficacy in hospitalized covid-19 patients. (ospublishers.com)
  • E - Early identification of sepsis is a critical step to improve the outcomes of patient. (csccm.org.cn)
  • 2016). However, not all patients with sepsis develop fever and those with hypothermia may have worse outcomes. (csccm.org.cn)
  • To evaluate the clinical outcomes of daptomycin therapy and adherence to treatment recommendations, a retrospective cohort study was conducted with patients that received daptomycin during the period of the study. (bvsalud.org)
Diagnosis1
  • Further, we anticipate that our targeted MS assays will have clinical benefit for the diagnosis, stratification, and treatment of MM patients. (bmj.com)
Multidrug1
  • however, the majority of MM patients ultimately relapse, necessitating the use of multidrug combinations. (bmj.com)
Enterococcus1
  • Vancomycin-resistant Enterococcus in an epidemic situation: screening at admission for patients at risk of carriage]. (bvsalud.org)
Molecular2
  • In previous studies of GCs, genomic and transcriptomic analyses have identified molecular signatures associated with phenotypes of the disease, such as patient subtypes and survival. (genomeweb.com)
  • Molecular modelling of glycopeptide 1 and GpalphaDG1 scFv suggested that their interaction occurs through hydrogen bonds and hydrophobic contacts involving amino acids from scFv (I51, Y33, S229, Y235, and P233) and R8 and alpha-mannose from Glycopeptide 1. (cnr.it)
Intensive care2
  • Herein, we report a hospital-based prospective monocentric study of a series made up of 22 adult patients who received tocilizumab out of a total of 139 patients admitted to the medical intensive care unit for moderate to severe forms of Covid-19 between February 2021 and October 2021. (ospublishers.com)
  • The dosage adjustment of vancomycin in severely ill patients admitted to an intensive care unit is important and requires more studies related to this area, as the work of a multidisciplinary body makes the treatment better and more specific. (bvsalud.org)
Sepsis6
  • 3. recite the factors that increase the risk of a patient getting sepsis and the patient types most like to get sepsis. (atsu.edu)
  • It is the 10th leading cause of death overall (2003) and is the most common cause of shock encountered by internists in the U.S. Despite aggressive treatment mortality ranges from 15% in patients with sepsis to 40-60% in patients with septic shock. (atsu.edu)
  • Only 30-50 percent of patients with sepsis have positive blood culture results. (atsu.edu)
  • 2016) and the management of patients is framed by the Surviving Sepsis Campaign guidelines with its renewed version in 2021 (Evans et al. (csccm.org.cn)
  • However, microcirculation may be impaired in a relative proportion of patients with sepsis (Joffre et al. (csccm.org.cn)
  • F - Fever is found in most - but not all - patients with sepsis. (csccm.org.cn)
Infection5
  • The increased use of invasive devices, such as catheters, and the expanding number of patients with impaired host defenses have contributed to the CoNS infection rate. (cdc.gov)
  • Should CoNS with decreased susceptibility to glycopeptides be reported to infection control? (cdc.gov)
  • are now much more often isolated from various diagnostic materials in systemic infection, both in hospitalized and in ambulatory patients. (medscimonit.com)
  • There were more than 4.8 million hospital admissions of adults with ABSSSI from 2005 through 2011, which included patients with cellulitis, erysipelas, wound infection and major cutaneous abscess. (prnewswire.com)
  • Prescribing vancomycin in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug resistant bacteria. (nih.gov)
Abundance1
  • MS-based validation using primary specimens detected 30 proteins with significantly higher abundance in patient MM cells than controls. (bmj.com)
POPULATIONS1
  • Stratified analysis of the comorbidities in patients with vancomycin-associated AKI further confirmed the necessity for different patient populations to be studied. (frontiersin.org)
Detection1
  • Until recently, classification of N-glycopeptide spectra in ProteinScape (detection of glycopeptide spectra and calculation of glycan and peptide moiety mass) has centered on glycan fragment distances and oxonium ion detection when using typical CID conditions on ion trap or qTof instruments (see application note LCMS-66)4. (news-medical.net)
Inhibits2
  • In Phase III data presented in August, Boehringer Ingelheim showed that a higher and a lower dose of dabigatran (Pradaxa) , which inhibits thrombin directly, were superior to warfarin for patients with atrial defibrillation, a heart arrhythmia frequently associated with strokes. (pharmexec.com)
  • It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. (lookformedical.com)
Assays1
  • Next, we developed targeted MS assays, and applied these to cell lines and primary patient samples to refine the list of candidate tumor markers. (bmj.com)
Adverse2
  • Two typical adverse drug reactions associated with IV vancomycin are severe local pain and thrombophlebitis (which affect about 1% of patients). (factmr.com)
  • Nephrotoxicity was discovered to be a rare adverse effect in later investigations using purer forms of vancomycin (0.1% to 1% of patients). (factmr.com)
Mortality2
  • The inadequate initial treatment of meningitis due to Listeria is associated in some studies with an increase in mortality, so the empirical guideline in immunosuppressed patients and in adults older than 60 years should include coverage against this microorganism. (epainassist.com)
  • Despite our efforts, the 90-day mortality rate of these patients remains up to 40% in septic shock. (csccm.org.cn)
Bacteremia4
  • We sought to determine risk factors for MDR AB bacteremia in patients colonized with MDR AB in the ICU. (biomedcentral.com)
  • Of the 200 patients colonized with MDR AB, 108 developed MDR AB bacteremia, and 92 did not. (biomedcentral.com)
  • Patients in the ICU, colonized with MDR AB, should be considered for minimizing invasive procedures and early removal of the invasive devices to prevent development of MDR AB bacteremia. (biomedcentral.com)
  • We conducted a retrospective, observational study among patients colonized with MDR AB admitted to our ICU to assess risk factors associated with the development of MDR AB nosocomial bacteremia. (biomedcentral.com)
Treatment5
  • Early and effective treatment of ABSSSI is critical to optimize patient recovery and for certain patients may also help to avoid potentially lengthy and costly hospital stays. (prnewswire.com)
  • To know the major causes of this disease progression, understand the basic processes that cause the progression from SIRS to septic shock, and describe the basic treatment plan in caring for these patients. (atsu.edu)
  • We are hopeful that AR-12 will emerge as a treatment option for patients suffering from COVID-19, ultimately saving lives and contributing to the global pandemic solution. (drugtargetreview.com)
  • Most patients (86.5%) received daptomycin as the second line of treatment, and 51.9% achieved clinical success. (bvsalud.org)
  • Similarly, ivermectin can result in serious consequences effects such as medication tolerance and nil response to in pregnant women and in patients suffering from treatment in acute otitis media, pneumonia, and urinary meningitis ( 15 ). (who.int)
Urine of patients3
  • Over 42% of strains were isolated from urine of patients with non-significant bacteriuria or as concomitant flora. (medscimonit.com)
  • Examination of enterococci isolated from urine of patients hospitalized showed 33.8% sensitive to norfloxacin and 84.6% sensitive to nitrofurantoin. (medscimonit.com)
  • Urine of patients with early prostate cancer contains lower levels of light chain fragments of inter-alpha-trypsin inhibitor and saposin B but increased expression of an inter-alpha-trypsin inhibitor heavy chain 4 fragment. (um.edu.my)
Adult patients3
  • Adult Patients (18 years of age or greater): 125 mg orally 4 times daily for 10 days. (nih.gov)
  • Adult Patients (18 years of age or greater): 500 mg to 2 g orally in 3 or 4 divided doses for 7 to 10 days. (nih.gov)
  • The study consisted of a series of 22 adult patients out of a total of 139 patients admitted to the unit between February 1,2021 and October 7,2021 for moderate, severe, or critical form of Covid-19. (ospublishers.com)
Classification2
  • Compound classification and ensuing glycopeptide identification is executed with ProteinScape 4.0 and the embedded search algorithm GlycoQuest. (news-medical.net)
  • Despite the fact that the classification workflow in ProteinScape has an explicit parameter to address this issue, the peptide mass of low abundant N-glycopeptides can be miscalculated at times, which can result in no or incorrect identifications. (news-medical.net)
Primarily2
  • These results indicated that P was composed primarily of glycopeptides, which impart the analgesic effects of M. androsaceus. (scirp.org)
  • The sugar portion of the glycopeptides was composed primarily of glucose (Glc) and mannose (Man) with the molar ratio of 9:1. (scirp.org)
Immune2
  • The study looked at 29 patients and demonstrated that the thrombocytopenia was immune mediated. (imedpub.com)
  • The infected person can remain as an asymptomatic carrier if possesses a capable immune system to fight against the bacteria, but in other cases, the listeriosis patient will present some symptoms that could be life threatening if not treated properly on time. (epainassist.com)
Vancomycin-associated1
  • Vancomycin-associated acute kidney injury (AKI) continues to pose a major challenge to both patients and healthcare providers. (frontiersin.org)
20011
  • and (iii) compare cognitive function of long-term stroke survivors with non-stroke persons.METHODS: Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) were administered to 10-year survivors from a population-based cohort of first-ever stroke patients included in the Lund Stroke Register, Sweden, in 2001-2002. (lu.se)
Dalbavancin1
  • Patients were randomly assigned to receive two doses of dalbavancin on days 1 and 8, or to receive intravenous vancomycin for at least 3 days with the option of switching to oral linezolid to complete 10 to 14 days of therapy. (wikipedia.org)
Synthetic2
  • 1,2 employed synthetic, and therefore well-defined, N-glycopeptides for the optimization of CID energy parameters, so as to attain the greatest possible quantities of data on both the glycan and peptide moiety within just one tandem MS experiment. (news-medical.net)
  • XYDALBA™ is a second generation, semi-synthetic lipoglycopeptide, which consists of a lipophilic side-chain added to an enhanced glycopeptide backbone. (prnewswire.com)
Conclusions1
  • CONCLUSIONS: This review provides an improved evidence base for both clinical care of individual anthrax patients and public health planning for wide-area aerosol releases of B. anthracis spores. (cdc.gov)
Study6
  • We conducted a retrospective, observational study of 200 patients colonized with MDR AB in the ICU at Severance Hospital, South Korea during the outbreak period between January 2008 and December 2009. (biomedcentral.com)
  • This was a retrospective, observational study of 200 patients colonized with MDR AB, admitted to the medical ICUs of Severance Hospital, Seoul, South Korea (a university, tertiary, referral hospital with two 15-bed medical ICUs) from January 2008 to December 2009. (biomedcentral.com)
  • As the impetus for this study, the researchers noted that the incidence of diffuse-type GCs (one of two major histological subtypes of GC) has increased in the US, and that increasing rates of GC in patients under 40 have also been reported in the US. (genomeweb.com)
  • Therefore, the aims of the study might have a significant clinical importance in daily practice as they would allow a more protocolized use of Tocilizumab in hospitalized covid-19 patients. (ospublishers.com)
  • The study demonstrated lower clinical success than that described in the literature because of patients who were not eligible according to the clinical guidelines. (bvsalud.org)
  • Of the 30 patients included in the present study, 80% were preterm. (bvsalud.org)
Endocarditis1
  • Physicians need to use additional parameters when treating patients with staphylococcal endocarditis. (biomedcentral.com)
Comorbidities1
  • The basic clinical information, vancomycin dosage and days, comorbidities and medication, laboratory indicators of the patients were recorded. (frontiersin.org)