• dura mater
  • Craniotomy is distinguished from craniectomy (in which the skull flap is not immediately replaced, allowing the brain to swell, thus reducing intracranial pressure) and from trepanation, the creation of a burr hole through the cranium in to the dura mater. (wikipedia.org)
  • tumors
  • Management paradigms are case specific and tailored to the individual needs of each patient, with state-of-the-art treatment protocols, clinical trials, vaccine development, surgical techniques, adjuvant therapies, and laboratory research aimed at improving outcomes - even on the most challenging types of tumors. (wikipedia.org)
  • Being a tertiary referral center for south Florida, the Caribbean, Central America, and the rest of Latin America, the University of Miami treats a large number of patients affected by all types of brain tumors. (wikipedia.org)
  • After radiation treatments for vestibular schwannomas, patients must receive MRIs annually due to the possibility of recurrence of secondary tumors. (wikipedia.org)
  • The most common neurological symptoms include: New onset headaches: headaches occur in roughly half of brain metastasis patients, especially in those with many tumors. (wikipedia.org)
  • acute
  • Up to now, the validity of PetCO2 monitoring in estimating PaCO2 during an acute posttraumatic craniotomy has not been studied. (biomedsearch.com)
  • We can conclude that during an acute craniotomy in SHI pts, PetCO2 does not reflect accurately PaCO2 and the monitoring of adequacy of ventilation should be based on repeated or continuous measurements of an arterial PCO2. (biomedsearch.com)
  • The (ICE) component comprises a catheter with platinum sensors that, when inserted into the brain allows for recording directly from the cerebral cortex of patients with acute brain injury. (wikipedia.org)
  • MRIs have shown evidence of Kernohan's notch from patients with traumatic head injury that are related to acute space-occupying lesions such as subdural hematoma, epidural hematoma, depressed skull fracture, or spontaneous intracerebral hematoma. (wikipedia.org)
  • electrode
  • Intracortical encephalogram signal analysis has two components: 1) an intracortical EEG multicontact electrode (ICE) that inserted through a patient's skull and deep into the grey matter of the patient, and 2) an artificial intelligent agent that is trained in neurological signal analysis. (wikipedia.org)
  • Electrode positioning varies from patient to patient, and electrodes can come in rows, in a grid array, or can be individually arranged. (wikipedia.org)
  • retrospective
  • The pooled evidence from three randomised controlled trials in Europe supports the retrospective observations that early (within 48 hours) application of decompressive craniectomy after "malignant" stroke may result in improved survival and functional outcome in patients under the age of 55, compared to conservative management alone. (wikipedia.org)
  • infection
  • Twenty-two patients (51.2%) received 24 "prophylactic" plastic surgery closures (i.e., in the absence of infection) for indications including previous craniotomy (n=22), XRT (n=19), and prior bevacizumab therapy (n=11). (ps-rc.org)
  • At least 40% of patients became susceptible to at least one infection, creating more interconnected risk factors along the way. (wikipedia.org)
  • The process is commonly known as "cell-saver" and is considered far superior to the use of blood from a donor, because it reduces the possibility of infection and provides more functional cells back to the patient. (wikipedia.org)
  • indications
  • Forty-two patients (97.7%) underwent previous craniotomy for indications including intracranial neoplasia (n=32), intracranial hemorrhage (n=5), seizure disorder (n=4), and hydrocephalus (n=1). (ps-rc.org)
  • intravenous
  • This device allows the patient to push a button to give pain medicine through an intravenous line and is frequently used for pain treatment after surgery and for other types of procedures. (clinicaltrials.gov)
  • Explore if using intravenous acetaminophen just before and just after a craniotomy can reduce the amount of opioids a patient needs, which results. (swedish.org)
  • craniectomy
  • This was a randomized trial comparing decompressive craniectomy to best medical therapy run between 2002 and 2010 to assess the optimal management of patients with medically refractory ICP following diffuse non-penetrating head injury. (wikipedia.org)
  • Lastly, despite being randomized, more patients in the craniectomy arm had unreactive pupils (after randomization but before surgery) than patients in the medical therapy arm, a potential confounding factor. (wikipedia.org)
  • After a craniectomy, the risk of brain injury is increased, particularly after the patient heals and becomes mobile again. (wikipedia.org)
  • clinical
  • Pupillometry, the measurement of pupil size and reactivity, is a key part of the clinical neurological exam for patients with a wide variety of neurological injuries. (wikipedia.org)
  • Numerous studies have shown the importance of pupil evaluation in the clinical setting, and pupillary information is used extensively in patient management and as an indication for possible medical intervention. (wikipedia.org)
  • Neuroscience
  • The idea first began circulating in the neuroscience community after some split-brain patients exhibited the alien hand syndrome, which led some scientists to believe that there must be two separate consciousnesses within the brain's left and right hemispheres in competition with one another once the corpus callosum is severed. (wikipedia.org)
  • infusion
  • A target plasma concentration is entered as ng/ml into the pump, which calculates its infusion rate according to patient factors like age and weight. (wikipedia.org)
  • functional
  • Factors associated with symptom-specific psychological and functional impact among acoustic neuroma patients. (semanticscholar.org)
  • Cortical stimulation mapping allows electrodes to be placed in exact locations to test brain function and identify if stimulation of the brain location causes a functional impairment in the patient. (wikipedia.org)
  • epilepsy
  • Craniotomies are often critical operations, performed on patients who are suffering from brain lesions or traumatic brain injury (TBI), and can also allow doctors to surgically implant deep brain stimulators for the treatment of Parkinson's disease, epilepsy, and cerebellar tremor. (wikipedia.org)
  • Attempting to treat epilepsy, van Wagenen studied and published the results of his surgeries, including the split-brain outcomes for patients. (wikipedia.org)
  • The diminished life expectancy associated with epilepsy patients has been documented by population-based studies in Europe. (wikipedia.org)
  • Cohort
  • Headache: a quality of life analysis in a cohort of 1,657 patients undergoing acoustic neuroma surgery, results from the acoustic neuroma association. (semanticscholar.org)
  • brain tissue
  • Craniotomy is an operation in which a piece of the skull is removed so doctors can remove a brain tumor or abnormal brain tissue. (osu.edu)
  • Before removing any brain tissue, the patient is awakened and the neurosurgeon creates a cortical map, using a small electrical stimulation device to observe the changes in the patient's condition when an area is stimulated. (wikipedia.org)
  • Paresthesias: patients often present with (hemiparesis), or weakness on only one side of the body, which is often a result of damage to neighboring brain tissue. (wikipedia.org)
  • Outcome
  • Acoustic neuroma surgery: outcome analysis of patient-perceived disability. (semanticscholar.org)
  • The National Institutes of Health Stroke Scale (NIHSS) uses pupillary response as a systematic assessment tool to provide a quantitative measure of stroke-related neurologic deficit and to evaluate acuity of stroke patients, determine appropriate treatment, and predict patient outcome. (wikipedia.org)
  • chronic subdural
  • Chronic subdural bleeds develop over a period of days to weeks, often after minor head trauma, though such a cause is not identifiable in 50% of patients. (wikipedia.org)
  • Case studies have shown that in patients with chronic subdural hematoma, a compressive deformity of the crus cerebri without an abnormal MRI signal may predict a better recovery in patients with Kernohan's notch. (wikipedia.org)
  • assess
  • OBJECTIVES: I. Assess the toxic effects of concurrent permanent iodine I 125 interstitial seed implants and polifeprosan 20 with carmustine implant (Gliadel wafers) in patients with recurrent or refractory malignant glioma. (clinicaltrials.gov)
  • Assess preliminary efficacy of this regimen in terms of progression free survival and overall survival of these patients. (clinicaltrials.gov)
  • Assess impact of this regimen on the quality of life and performance status of these patients. (clinicaltrials.gov)
  • Assess site of tumor progression following this regimen in these patients. (clinicaltrials.gov)
  • intracranial
  • Interictal spikes and their association with performance on cognitive tasks in patients undergoing intracranial monitoring. (kimmelcancercenter.org)
  • Patients with third ventricular colloid cysts become symptomatic when the tumor enlarges rapidly, causing CSF obstruction, ventriculomegaly, and increased intracranial pressure. (wikipedia.org)
  • radiation
  • PURPOSE: Phase I trial to study the effectiveness of internal radiation therapy plus carmustine implants in treating patients who have recurrent or refractory malignant glioma. (clinicaltrials.gov)
  • dose
  • These side effects are often controlled by either altering the administered dose (decreasing or in some cases, increasing the dose) or by administering other sedatives that allow the patient to tolerate or lose awareness of the side effect. (wikipedia.org)
  • In addition, patients may experience adverse side effects from these drugs, such as myopathy and opportunistic infections, which can be alleviated by decreasing the dose. (wikipedia.org)
  • general
  • Additionally, patients not receiving intubated general anesthesia tend to recover more quickly after surgery. (osu.edu)
  • In general, a craniotomy will be preceded by an MRI scan which provides an image of the brain that the surgeon uses to plan the precise location for bone removal and the appropriate angle of access to the relevant brain areas. (wikipedia.org)
  • newly diagnosed
  • To confirm that the addition of rindopepimut/GM-CSF to adjuvant temozolomide improves overall survival in patients with newly diagnosed EGFRvIII. (swedish.org)
  • This treatment is tailored to newly diagnosed patients with glioblastoma multiforme, and aims to activate the patients's immune system against the tumor antigen to prevent recurrence using HSPPC-96. (wikipedia.org)
  • Treatment
  • Automated pupillometry removes subjectivity from the pupillary evaluation, providing more accurate and trendable pupil data, and allowing earlier detection of changes for more timely patient treatment. (wikipedia.org)
  • Treatment consists mainly of: Corticosteroids - Corticosteroid therapy is essential for all patients with brain metastases, as it prevents development of cerebral edema, as well as treating other neurological symptoms such as headaches, cognitive dysfunction, and emesis. (wikipedia.org)
  • Dysosmia tends to go away on its own but there are options for treatment for patients that want immediate relief. (wikipedia.org)
  • neurological
  • For more than 100 years, clinicians have evaluated the pupils of patients with suspected or known brain injury or impaired consciousness to monitor neurological status and trends, checking for pupil size and reactivity to light. (wikipedia.org)
  • Today, clinicians routinely evaluate pupils as a component of the neurological examination and monitoring of critically ill patients, including patients with traumatic brain injury and stroke. (wikipedia.org)
  • However, brain metastases should be considered in any cancer patient who presents with neurological or behavioral changes. (wikipedia.org)
  • ventricular
  • Colloid cyst symptoms have been associated with 4 variables: cyst size, cyst imaging characteristics, ventricular size, and patient age. (wikipedia.org)
  • traumatic
  • Alterations of the pupil light reflex, size of the pupil, and anisocoria (unequal pupils) are correlated with outcomes of patients with traumatic brain injury. (wikipedia.org)
  • management
  • As a result of these strikingly high complication rates, plastic surgeons have increasingly become consulted for management of craniotomy incisions in patients deemed to be at "high risk" for wound healing complications. (ps-rc.org)
  • Various management options exist depending on the severity of symptoms and their effect on the patient. (wikipedia.org)
  • occurs
  • Bacterial meningitis or viral meningitis occurs in about 0.8 to 1.5% of individuals undergoing craniotomy. (wikipedia.org)
  • Split-brain patients have been subjects for numerous psychological experiments that sought to discover what occurs in the brain now that the primary interhemispheric pathways have been disrupted. (wikipedia.org)
  • Ataxia: when metastasis occurs to the cerebellum, patients will experience various difficulties with spatial awareness and coordination. (wikipedia.org)
  • often
  • The most common side effects reported by patients receiving this medication are a sense of extreme "dizziness" (often short lived, a common side effect of other fast-acting synthetic phenylpiperidine narcotics such as fentanyl and alfentanil) and intense itching (pruritus), often around the face. (wikipedia.org)
  • After surgery, the split-brain patients are often given extensive neuropsychological assessments. (wikipedia.org)
  • Within a year Mayfield had so many patients that he was often working 90 hours a week, with 7 to 8 cases a day and frequent late-night trips to rural hospitals. (wikipedia.org)
  • study
  • Assessment of study end-points was performed by an intensive care specialist blinded (like the patient) to the received hypnotic. (minervamedica.it)
  • After completion of study, patients are followed up at 1month and 1 year. (osu.edu)
  • RESULTS: Forty-three patients (64 procedures) were included in the study. (ps-rc.org)
  • PROJECTED ACCRUAL: A total of 12-18 patients will be accrued for this study within 18 months. (clinicaltrials.gov)