Patients no reflow phenomenon. Medical search. Frequent questions

In this study, we sought to evaluate the relationship between FAR and severity of CAD, long-term prognosis in non-ST elevation acute coronary syndrome (NSTE-ACS) patients firstly implanted with drug-eluting stent (DES). (hindawi.com)
No-flow phenomenon in patients with acute myocardial infarction associated with poor outcomes. (standardofcare.com)
Embolization can occur spontaneously or after percutaneous intervention in coronary arteries or venous grafts and have an important role in the no-reflow phenomenon after acute myocardial infarction. (standardofcare.com)
1. Danesh Sani SH, Eshraghi A, Shahri B, Vejdanparast M. No-reflow phenomenon in patients with STelevation acute myocardial infarction, treated with primary percutaneous coronary intervention: a study of predictive factors. (razavihospital.ir)
Intracoronary adenosine administered during percutaneous intervention in acute myocardial infarction and reduction in the incidence of "no reflow" phenomenon. (razavihospital.ir)
6. Brosh D, Assali AR, Mager A, Porter A, Hasdai D, Teplitsky I, Rechavia E, Fuchs S, Battler A, Kornowski R. Effect of no-reflow during primary percutaneous coronary intervention for acute myocardial infarction on six-month mortality. (razavihospital.ir)
No-reflow phenomenon and lesion morphology in patients with acute myocardial infarction J . Circulation, 2002, 105(18):2148-2152. (xml-journal.net)
Myocardial perfusion patterns related to Thrombolysis In Myocardial Infarction perfusion grades after coronary angioplasty in patients with acute anterior wall myocardial infarction J . Circulation, 1996, 93(11):1993-1999. (xml-journal.net)
One patient in the control group died after developing persistent SF-NR and acute MI post-PCI. (eurekaselect.com)
In this study, we aim to define the role of endothelin in regulating coronary microvascular blood flow and myocardial perfusion following PCI in patients with non-ST elevation acute coronary syndromes (NSTACS), by assessing whether adjunctive therapy with a selective endothelin A (ET A ) receptor antagonist acutely improves postprocedural coronary microvascular blood flow. (bmj.com)
Following percutaneous coronary intervention (PCI) for acute coronary syndromes, rise in endothelin-1 (ET-1) levels, a potent vasoconstrictor produced by the vascular endothelium, has been proposed as a potential mediator of reperfusion injury and 'no reflow' phenomenon. (bmj.com)
Following acute cervical spinal cord decompression, a subset of patients may develop acute postoperative paralysis due to Reperfusion Injury (RPI)/White Cord Syndrome (WCS). (surgicalneurologyint.com)
For 7 patients, new acute postoperative neurological deficits were appropriately attributed to MR-documented RPI/WCS syndromes (i.e. hyperintense cord signals). (surgicalneurologyint.com)
Patients with acute postoperative neurological deficits following cervical spine surgery must undergo MR studies to rule out extrinsic cord pathology before being diagnosed with RPI/WCS. (surgicalneurologyint.com)
Dorobanțu, Maria , Factors associated with use of percutaneous coronary intervention among elderly patients presenting with ST segment elevation acute myocardial infarction (STEMI): Results from the ISACS-TC registry , «INTERNATIONAL JOURNAL OF CARDIOLOGY», 2016, 217, pp. (unibo.it)
Early Computed Tomography Coronary Angiography and Preventative Treatment in Patients with Suspected Acute Coronary Syndrome A secondary analysis of the RAPID-CTCA trial. (amedeo.com)

However, none has addressed the association between FAR and severity of coronary artery disease (CAD), clinical outcome in NSTE-ACS patients firstly implanted with drug-eluting stent (DES). (hindawi.com)
Prompt recognition and effective management of complications, such as coronary perforation, no-reflow phenomenon, or stent thrombosis, are crucial. (alliedacademies.org)
To prevent this condition in patients with coronary lesions containing fresh thrombi, it is now possible to aspirate clots through catheters before stent implantation. (grupocorpal.com)
Nowadays, thoracic aortic endovascular repair (TEVAR) provides a potential treatment option for the patient with ATAAD, but traditional stent grafts (SGs), which are not designed for the ATAAD, are inapplicable to the unique anatomy of the aortic arch. (bvsalud.org)
The control group (n=72) comprised of patients who had undergone conventional PCI technique before the routine availability of distal embolic protection devices, with balloon pre-dilatation of the target lesion followed by stent deployment and optional use of intragraft verapamil or intravenous abciximab. (eurekaselect.com)
BACKGROUND: Deferring stent after mechanical flow restoration has been proposed as a strategy to reduce the risk of "no reflow" in patients with STEMI undergoing primary percutaneous coronary intervention (pPCI). (ox.ac.uk)
An unusual no-reflow phenomenon due to neointimal tissue embolization during drug eluting balloon intervention in stent restenosis: A case report. (amedeo.com)

Cyclosporin at the time of percutaneous coronary intervention (PCI) has been found to deliver a 40 percent reduction in infarct size in patients with reperfusion injury. (standardofcare.com)
Three distinct pathophysiological processes are critical in the development of 'no reflow' after PPCI for STEMI: distal embolization, ischemia-reperfusion injury, and individual susceptibility [ 4 ]. (biomedcentral.com)
The phenomenon has a multifactorial pathogenesis including: distal embolization, ischemia-reperfusion injury, and individual predisposition of coronary microcirculation to injury. (unipr.it)
Cryonics patients frequently experience ischemic & reperfusion injury between the time when the heart stops and cryostorage begins. (benbest.com)

Vitamin D deficiency predicts the no-reflow phenomenon in STEMI patients undergoing primary percutaneous coronary intervention. (escardio.org)
We aimed to investigate the comparative predictive values of different biomarkers for the occurrence of MVO in a large cohort of reperfused STEMI patients. (biomedcentral.com)
This study included 128 STEMI patients. (biomedcentral.com)
A biomarker model for prediction of MVO, which could easily be applied in a broad range of STEMI patients, might provide a practicable and cost effective alternative to CMR. (biomedcentral.com)
2. CONCLUSIONS: A deferred stenting strategy could be a feasible alternative to the conventional approach with immediate stenting in "selected" STEMI patients undergoing pPCI. (ox.ac.uk)

In contrast, secondary Raynaud phenomenon also reflects structural microvascular abnormalities. (medscape.com)
Lack of myocardial reperfusion in the presence of a patent coronary artery is referred to as a no-reflow phenomenon and is attributed to microvascular dysfunction. (standardofcare.com)
Microvascular obstruction and the no-reflow phenomenon after percutaneous coronary intervention J . Circulation, 2008, 117(24):3152-3156. (xml-journal.net)
Slow flow and no-reflow phenomenon (SF-NR) in saphenous vein grafts (SVG) stenting is related to the occurrence of distal plaque embolization, platelet activation and microvascular vasospasm. (eurekaselect.com)
Previously, Adlbrecht et al randomly assigned patients to receive intravenous BQ-123 at the onset of primary PCI for ST elevation myocardial infarction and demonstrated improved microvascular function using cardiac MRI at 6 days after PCI and smaller infarct sizes. (bmj.com)

Herrick (2005) reviewed the pathogenesis of Raynaud phenomenon and describes the mechanisms under 3 categories: vascular, neural, and intravascular abnormalities. (medscape.com)

In a variable proportion of patients presenting with ST-segment elevation myocardial infarction, ranging from 5% to 50%, primary percutaneous coronary intervention achieves epicardial coronary artery reperfusion but not myocardial reperfusion, a condition known as no-reflow. (unipr.it)
Role of deferred stenting in patients with ST elevation myocardial infarction treated with primary percutaneous coronary intervention: A systematic review and meta-analysis. (ox.ac.uk)
OBJECTIVES: We conducted a meta-analysis of studies comparing deferred stenting strategy versus the conventional approach with immediate stenting in patients with ST elevation myocardial infarction. (ox.ac.uk)

This preventive measure often prevents distal embolism and the "non-reflow" phenomenon in patients with thrombotic lesions. (grupocorpal.com)

However, it is conceivable that the relevance of each pathogenetic component of no-reflow is different in different patients, thus explaining the occurrence of no-reflow despite the use of mechanical thrombus aspiration. (unipr.it)
Data from 163 consecutive patients who underwent PCI of SVG lesions without visible macro-thrombus without use of distal embolic protection device over a 10-year period were reviewed. (eurekaselect.com)
Patients with visible macro-thrombus in the vein graft were excluded from the study, since these patients underwent PCI with use of the distal embolic protection (filter). (eurekaselect.com)

Susceptibility vessel sign, a predictor of long-term outcome in patients with stroke treated with mechanical thrombectomy. (unibe.ch)

A total of 105 consecutive patients with 110 calcified lesions underwent IVL. (frontiersin.org)
Up to 30% of patients undergoing percutaneous coronary intervention (PCI) have calcified lesions ( 1 ). (frontiersin.org)
This retrospective, observational study included consecutive patients with calcified coronary lesions treated with IVL from December 31, 2018 to December 31, 2020 at the Centro Cardiologico Monzino, University of Milan, Italy. (frontiersin.org)
Chronic ischemic lesions and presence of patent foramen ovale in young adults with embolic stroke of undetermined source - Results of the Young ESUS Patient Registry. (unibe.ch)
In carefully selected subgroup of SVG lesions without visible macrothrombus, a strategy of prophylactic intra-graft administration of abciximab and verapamil, combined with direct stenting of the graft lesion without pre-dilatation, can be safely accomplished without any significant risk of slow-flow/no-reflow phenomenon. (eurekaselect.com)
Clinical work and research scope includes complex coronary lesions, re-perfusion damage during intervention, treatment of no reflow phenomenon, contrast agent nephropathy prevention and treatment, etc. (escardio.org)

12. Galiuto L. Optimal therapeutic strategies in the setting of post-infarct no reflow: the need for a pathogenetic classification. (razavihospital.ir)

Although ischemia in these layers is rare, certain procedures place patients at risk for possible events, such as cardiopulmonary bypass, coronary angiography, and endovascular coil embolization. (bvsalud.org)

Methods and Results The FAST-3 trial was administered to 100 patients suffering from AMI. (go.jp)
Methods: Retrospective chart review of patients undergoing rhinoplasty who were divided into decades of age. (bvsalud.org)
METHODS: The patients with no reflow phenomenon detected in the salvage operations of replanted/revascularized digits between the years 2017 and 2020 were included in the study. (bvsalud.org)
METHODS: Patients treated for FG-associated dead spaces in their perianal region between the years 2017 and 2021 were included in the study. (bvsalud.org)
METHODS: A longitudinal cohort of patients (2007 to 2014, n = 20,642) who underwent PCI to SVGs in the British Cardiovascular Intervention Society database was formed. (worktribe.com)
Methods In a randomised, double-blinded, placebo-controlled trial, 23 NSTACS patients were enrolled to receive an intracoronary infusion of placebo (n=11) or BQ-123 (n=12) immediately before PCI. (bmj.com)

High-risk patients often present with challenging vascular access due to previous interventions, severe calcification, or tortuosity. (alliedacademies.org)

There are several proposed mechanisms for this phenomenon. (wikipedia.org)
Several recent studies have shown that biomarkers and other easily available clinical parameters can predict the risk of no-reflow and can help in the assessment of the multiple mechanisms of the phenomenon. (unipr.it)
Thus, in this review article, for the first time, we propose a personalized management of no-reflow on the basis of the assessment of the prevailing mechanisms of no-reflow operating in each patient. (unipr.it)

Rescue death (or reflow syndrome) is a hypothesized fatal condition that can occur after blood pools in a part of the body for a prolonged period such as during suspension trauma. (wikipedia.org)
The early postoperative period in CABG patients is associated with systemic inflammatory response syndrome (SIRS), which is complicated with multiple organ dysfunction and high mortality in 5%-16% of cases (EACTA 2007 data) [ 1 , 2 ]. (hindawi.com)
Patients with pre-operatively reduced left ventricular (LV) function are at higher risk of post-operative low-cardiac output syndrome requiring inotropic or mechanical circulatory support. (ecrjournal.com)

A total of 1138 consecutive NSTE-ACS patients firstly implanted with DES from January 2017 to December 2018 were recruited in this study. (hindawi.com)
The present investigation (Figure 1 ) was a single-center, observational, prospective cohort study among 1206 consecutive NSTE-ACS patients firstly implanted with DES at Department of Cardiology, Zhongda Hospital, Jiangsu, China, from January 2017 to December 2018. (hindawi.com)

The dynamics of those receptors expression on monocyte surface of patients with uncomplicated SIRS course followed coronary artery bypass surgery (CABG) was studied. (hindawi.com)

This approach enhances patient outcomes by leveraging the collective expertise and experience of the team [ 2 ]. (alliedacademies.org)
In patients with significant comorbidities, including renal dysfunction or heart failure, medication adjustments and monitoring ensure optimal therapeutic outcomes and minimize adverse events. (alliedacademies.org)
A well-prepared team with access to specialized equipment and bail-out strategies can significantly improve patient outcomes in such scenarios. (alliedacademies.org)
CONCLUSIONS: In this contemporary cohort, EPDs were used more commonly in higher risk patients but were associated with similar clinical outcomes in multivariate analyses. (worktribe.com)

In the authors' centre a total of 364 patients with a severely reduced LVEF ≤20% were operated during a six-year study period. (ecrjournal.com)

RESULTS: The phenomenon of 'no reflow' was encountered in 35 digits of 22 patients who underwent salvage surgery due to vascular compromise. (bvsalud.org)
The patients who underwent the pedicled gracilis muscle flap surgery were included in group 1, whereas group 2 consisted of the patients with no additional surgical procedure for dead spaces but only the reconstruction of the soft tissue defects. (bvsalud.org)

reflows: This phenomenon releases processes. (babyfreunde.de)

In conclusion, FAR was associated independently with the severity of CAD and prognosis, helping to improve risk stratification in NSTE-ACS patients firstly implanted with DES. (hindawi.com)
Despite of the use of current guideline-recommended therapies, including prompt coronary revascularization, dual antiplatelet therapy, and intensive lipid-lowering therapy, ACS patients still have a poor prognosis [ 1 - 3 ]. (hindawi.com)
Thus, the aim of the present study is to investigate the relationship between FAR and severity of CAD measured by the Gensini Score (GS), and the prognostic value of FAR in predicting long-term prognosis in NSTE-ACS patients firstly implanted with DES. (hindawi.com)
Of note, no-reflow is associated with a worse prognosis at follow-up. (unipr.it)

Patients often describe 3 phases of change: initial white (vasoconstriction), followed by blue (cyanosis), and then red (rapid blood reflow). (medscape.com)

Assessing clinical factors, such as age, comorbidities (e.g., diabetes, renal dysfunction), and frailty, alongside anatomical considerations (e.g., left main or multivessel disease), guides appropriate patient selection and the choice of revascularization strategies. (alliedacademies.org)
RESULTS: Patients in the EPD group were older, had more comorbidities, and had a higher prevalence of moderate to severe left ventricular systolic dysfunction. (worktribe.com)

In the control group, 13% patients developed cardiac enzyme elevation 3 times more than normal after the PCI as compared to 1% in the novel strategy group (P (eurekaselect.com)
In recent years further efforts were made to elucidate the meaning of beating-heart concepts for patients with specific extracardiac and cardiac risk factors for extracorporeal circulation and cardioplegic arrest. (ecrjournal.com)

Young women who have had Raynaud phenomenon alone for more than 2 years and have not developed any additional manifestations are at low risk for developing an autoimmune disease. (medscape.com)
However, the success of PCI in complex cases heavily relies on the effective management of high-risk patients. (alliedacademies.org)
Precise risk stratification plays a pivotal role in managing high-risk patients undergoing complex PCI. (alliedacademies.org)
Incorporating risk scores and predictive models helps in identifying patients who would benefit most from revascularization and guides decision-making. (alliedacademies.org)
Thorough pre-procedural planning is crucial in managing high-risk patients. (alliedacademies.org)
Managing high-risk patients undergoing complex PCI requires careful consideration of pharmacotherapy. (alliedacademies.org)
High-risk patients require diligent post-procedural care and close follow-up. (alliedacademies.org)
Small vessel disease burden and risk of recurrent cerebrovascular events in patients with lacunar stroke and intracerebral haemorrhage attributable to deep perforator arteriolopathy. (unibe.ch)
However, subsequent prospective randomised studies and meta-analyses comparing OPCAB and CCAB surgery were performed on low-risk patients or mixed-risk populations. (ecrjournal.com)
85 patients with at least 2 classical cardiovascular risk factors but without significant CAD served as controls. (biomedcentral.com)
Overall, we do not believe that these two trials' results will change prescribing practices (we do not think that most HCPs had very serious safety concerns, if any, about DPP-4 inhibitors to begin with), perhaps with slightly more reticence to prescribe DPP-4 inhibitors to patients at risk for heart failure and with slightly more reassurance on pancreatic safety risks. (closeconcerns.com)
however, it was instructive to learn that saxagliptin did not have a significant impact on the risk of overall hypoglycemia unless patients were on sulfonylureas, or if they had a baseline A1c below 7% and were on combination therapy involving insulin. (closeconcerns.com)

Raynaud phenomenon manifests as recurrent vasospasm of the fingers and toes and usually occurs in response to stress or cold exposure. (medscape.com)

Several therapeutic strategies have been tested for the prevention and treatment of no-reflow. (unipr.it)

Secondary Raynaud phenomenon should be distinguished from primary Raynaud phenomenon (Raynaud disease). (medscape.com)
Secondary Raynaud phenomenon is a designation usually used in the context of vasospasm associated with a variety of rheumatologic and non-rheumatologic diseases, environmental exposures, and/or medications. (medscape.com)
In some studies, 46%-81% of affected patients have secondary Raynaud phenomenon. (medscape.com)
Therapy for secondary Raynaud phenomenon must be tailored to the underlying disorder. (medscape.com)
Patients with secondary Raynaud phenomenon are more likely to require pharmacologic therapy. (medscape.com)

This article aims to explore strategies for optimizing safety and efficacy in complex PCI procedures, focusing on the management of patients with significant comorbidities, anatomical challenges, and procedural complexities [ 1 ]. (alliedacademies.org)
Management of no-reflow phenomenon in the catheterization laboratory. (razavihospital.ir)
Instead, treatment should consist of removing a patient from suspension and providing basic trauma care, starting with airway management (which could theoretically be impeded by requiring a patient to be kept in a seated position)[citation needed]. (wikipedia.org)
Although open surgery is still the gold standard for the treatment of ATAAD, some patients, with advanced age and multiple comorbidities, can only receive medical management alone. (bvsalud.org)
Management of CHD emphasizes early complete repair before the heart and the patient deleteriously adapt to the abnormal physiology. (medscape.com)

For primary Raynaud phenomenon, the first line of therapy consists of lifestyle measures. (medscape.com)
Primary Raynaud phenomenon is related to functional alterations alone. (medscape.com)

Optimal hemostasis strategies, including vascular closure devices or radial artery compression techniques, minimize bleeding complications and improve patient comfort and recovery [ 3 ]. (alliedacademies.org)
Therefore, SIRS course and criteria as well as the ways of predicting its complications are of a great interest in this group of patients. (hindawi.com)

Objective: To associate the rhinoplasty results with patients' age by anthropometric measurements. (bvsalud.org)
For these patients, significantly reduced peri-operative mortality and comparable long-term results were found. (ecrjournal.com)
2). RESULTS: Eight studies (three randomized and five non-randomized) were deemed eligible, accounting for a total of 2101 patients. (ox.ac.uk)
Nevertheless, despite improved surgical techniques and operative results, CHD remains the leading cause of death among all patients with congenital defects. (medscape.com)
Confidence in choosing the right cancer treatment for your patient comes from seeing results. (erbitux.com)
Experience and data have shown ERBITUX with FOLFIRI (irinotecan, fluorouracil, and leucovorin) can deliver the real, tangible results you need to see for appropriate patients with KRAS wild-type, EGFR-expressing metastatic colorectal cancer (mCRC). (erbitux.com)
Because when you see results, your patient sees hope. (erbitux.com)

In the English literature (i.e. excluding 2 Japanese studies), 9 patients were identified with postoperative RPI/WCS following cervical surgical procedures. (surgicalneurologyint.com)

Our article discusses few of the patents related to strategies for preventing slow-flow/no-reflow phenomenon in SVG percutaneous coronary intervention (SVG PCI). (eurekaselect.com)
Conclusions: In recent years several distal embolic protection devices have been granted patents for minimizing the chance of slow-flow/no-reflow phenomenon. (eurekaselect.com)

The same should not be said for older patients and male patients with Raynaud phenomenon, as vasospastic symptoms may predate systemic disease by as many as 20 years. (medscape.com)
Although Raynaud phenomenon has been described with various autoimmune diseases, the most common association is with progressive systemic sclerosis (90% in individuals with scleroderma ) and mixed connective-tissue disease (85% prevalence). (medscape.com)
Raynaud phenomenon has also been described with such diverse diseases as systemic lupus erythematosus and other disorders not classified as autoimmune, including frostbite , vibration injury, polyvinyl chloride exposure, and cryoglobulinemia . (medscape.com)

CONCLUSIONS: It was demonstrated that dobutamine infusion at a rate of 4 µg·kg-1·min-1 intraoperatively and at 2 µg·kg-1·min-1 postoperatively has favorable effects on the vascular compromise derived from no reflow of proximal artery. (bvsalud.org)
CONCLUSIONS: Perianal dead spaces accompanying many of the patients with FG provide appropriate conditions for bacterial colonization. (bvsalud.org)

Monitor patients for signs and symptoms of pulmonary toxicity. (erbitux.com)

If these prove inadequate, the patient may benefit from pharmacologic treatment. (medscape.com)
11. Barcin C, Denktas AE, Lennon RJ, Hammes L, Higano ST, Holmes DR, Garratt KN, Lerman A. Comparison of combination therapy of adenosine and nitroprusside with adenosine alone in the treatment of angiographic no‐ reflow phenomenon. (razavihospital.ir)
Moreover, it is spontaneously reversible in some patients, thus suggesting that it might be amenable to treatment also when we fail to prevent it. (unipr.it)
Incidence and treatment of no-reflow after percutaneous coronary intervention J . Circulation, 1994, 89(6):2514-2518. (xml-journal.net)
Stenting has become standard treatment for patients undergoing percutaneous coronary intervention. (bmj.com)

Artificial Intelligence for Assessment of Endotracheal Tube Position on Chest Radiographs: Validation in Patients From Two Institutions. (amedeo.com)

METHOD: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science and Scopus databases were searched from inception to July 2023 for publications on the prognostic significance of CS on DECT after EVT in patients with AIS. (bvsalud.org)

Although this is usually a temporary situation, it can seriously aggravate the patient until resolved with intracoronary adenosine and antiplatelet drugs. (grupocorpal.com)

Anatomy24

Organisms16

Diseases25

Chemicals and Drugs31

Analytical, Diagnostic and Therapeutic Techniques and Equipment54

Psychiatry and Psychology16

Phenomena and Processes91

Disciplines and Occupations7

Humanities2

Information Science6

Health Care13

Acute16

Stent7

Reperfusion injury4

STEMI5

Microvascular5

Pathogenesis1

Myocardial infarction3

Prevents distal1

Thrombus3

Predictor1

Lesions6

Pathogenetic1

Embolization1

Methods6

Interventions1

Mechanisms3

Syndrome3

20172

Coronary artery1

Outcomes4

Severely reduced1

Underwent2

Processes1

Prognosis4

Initial1

Dysfunction2

Cardiac2

Risk12

Recurrent1

Therapeutic1

Secondary5

Management5

Primary2

Complications2

Results7

Postoperative1

Slow-flow2

Systemic3

CONCLUSIONS2

Symptoms1

Treatment5

Assessment1

20231

Intracoronary1