AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesNamed GroupsHealth Care
Bone TransplantationBone BanksBone and BonesLiver TransplantationTransplantation, HomologousBone Marrow TransplantationKidney TransplantationBone RemodelingHematopoietic Stem Cell TransplantationTransplantation, AutologousHeart TransplantationLung TransplantationBone DensityStem Cell TransplantationTransplantation ConditioningGraft SurvivalOrgan TransplantationBone MarrowBone ResorptionBone Marrow CellsGraft RejectionPancreas TransplantationTissue DonorsIslets of Langerhans TransplantationTransplantationTransplantation ImmunologyCell TransplantationTransplantation ChimeraBone NeoplasmsBone DevelopmentBone DiseasesGraft vs Host DiseaseImmunosuppressive AgentsTransplantation, IsogeneicTreatment OutcomeLiving DonorsTransplantation, HeterotopicCord Blood Stem Cell TransplantationBone RegenerationHeart-Lung TransplantationTime FactorsTissue and Organ ProcurementTransplantation ToleranceRetrospective StudiesBone MatrixPeripheral Blood Stem Cell TransplantationImmunosuppressionHistocompatibility TestingLiver FailureFetal Tissue TransplantationPostoperative ComplicationsSkin TransplantationMesenchymal Stem Cell TransplantationTransplantation, HeterologousRecurrenceWhole-Body IrradiationWaiting ListsBone Diseases, MetabolicHistocompatibility
Allogeneic hematopoietic stem cStemPeripheralBench to bedsHematologic malignanciesAcuteTransplantCellular TherapySevere2000DonorMalignanciesPBSCTDisordersRelapse after allogeneicChronicOutcomeConditioning regimensDiseasesCommon complicationCellsRecurrentUnderwentCentersUnderlying bone marrowSurvivorsMetabolicTransplantsOutcomes2023QuestionnairesCortical boneBloodPatient'sMethodsDiagnosisAntibodyInfectionComplicationsTreatmentLeukemiaCyclophosphamideAdultPsychologicalDonorsBiopsyCancer CenterEdemaNormal bone
Allogeneic hematopoietic stem c5
Stem40
Peripheral4
  • Genomic DNA of a patient diagnosed with nonobstructive azoospermia and with the history of allogenic bone marrow transplantation from his sister due to chronic myeloid leukemia was isolated from peripheral blood in order to screen Y chromosome microdeletions. (istanbul.edu.tr)
  • We studied three SCID patients who were transplanted with unmodified mobilized peripheral blood from HLA-identical family sex-mismatched members. (nih.gov)
  • Peripheral blood mononuclear cells (PBMCs) were isolated by Ficoll-Hypaque gradient from the blood samples collected at days 0, 7, 14, 28, and final day of transplantation. (magiran.com)
  • Enzyme replacement therapy (ERT) appears safe and effective for peripheral manifestations in patients with Gaucher disease types I and III, Fabry disease, mucopolysaccharidosis I (Hurler, Hurler-Scheie, and Scheie syndromes), mucopolysaccharidosis II (Hunter syndrome), mucopolysaccharidosis VI (Maroteaux-Lamy syndrome), Pompe disease, and recently Batten disease (neuronal ceroid lipofuscinoses, CLN2). (medscape.com)
Bench to beds1
Hematologic malignancies2
  • Sixteen evaluable patients with advanced hematologic malignancies were treated with twice daily TBI using a high-energy source (18-24 MV). The first patient cohort ( n = 11) received a total dose of 14.4 Gy in nine fractions, and the second cohort ( n = 5) received doses escalated to 15.3 Gy. (nature.com)
  • While allogeneic transplantation can be life saving for patients with hematologic malignancies, or inherited disorders such as several forms of immuno-deficiency, the transplant-related side effects and complications remain the biggest hurdles. (stanford.edu)
Acute6
  • This is a multicenter, open-label, Phase 1/2a dose escalation and expansion study of orally administered emavusertib (CA-4948) monotherapy in adult patients with Acute Myelogenous Leukemia (AML) or high risk Myelodysplastic Syndrome (MDS). (rochester.edu)
  • The increasing success of intensive consolidation chemotherapy (CCT) as an alternative to bone marrow transplant (BMT) in acute myeloid leukaemia (AML) necessitates comparison of the impact on quality of life (QoL) of these two treatment modalities. (ox.ac.uk)
  • Objective To evaluate viral loads at different stages of disease progression in patients infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first four months of the epidemic in Zhejiang province, China. (bmj.com)
  • Patients who benefit most from the transfusion of RBCs include those with chronic anemia resulting from kidney failure or gastrointestinal bleeding, and those with acute blood loss resulting from surgery or trauma. (utmb.edu)
  • A New Complex Karyotype Involving a KMT2A-r Variant Three-Way Translocation in a Rare Clinical Presentation of a Pediatric Patient with Acute Myeloid Leukemia. (cancerindex.org)
  • Patients with childhood acute myeloid leukemia (AML) with complex karyotypes (CKs) have a dismal outcome. (cancerindex.org)
Transplant21
  • A short-chain fatty acid made by bacteria in the gut could play an important role in graft-versus-host disease (GVHD) after allogeneic bone marrow transplant in mice. (oncologynurseadvisor.com)
  • What Is a Bone Marrow Transplant? (medlineplus.gov)
  • A future therapy could work by collecting the CMV-thwarting antibodies from patients who have been exposed to the virus and who are undergoing bone marrow transplant. (sciencedaily.com)
  • The antibodies would be purified and multiplied in the lab, then returned to the patient after transplant. (sciencedaily.com)
  • The virus can cause life-threatening complications such as pneumonia, hepatitis and gastroenteritis and has plagued allogenic transplant patients for decades. (sciencedaily.com)
  • Three months later, the researchers gave the mice a bone marrow transplant, effectively wiping away their immune systems and replacing them with new donor marrow. (sciencedaily.com)
  • Novel approach to restore the normal bone remodeling and improve the bone quality may be needed in order to effectively decrease bone fracture rate in kidney transplant recipients. (exposed-skin-care.net)
  • Keywords: Uremic osteodystrophy Bone loss Fracture Kidney transplantation INTRODUCTION Metabolic bone diseases in kidney transplant recipients may include pre-existing uremic osteodystrophy osteoporosis bone fracture osteonecrosis and bone pain syndrome. (exposed-skin-care.net)
  • Kidney transplant recipients are now living longer than ever and thus proper management of bone disease has become an increasingly important a part of their care. (exposed-skin-care.net)
  • PRE-EXISTING UREMIC OSTEODYSTROPHY Several different types of renal osteodystrophy can be encountered in kidney transplant patients. (exposed-skin-care.net)
  • Osteitis fibrosa cystica Prolonged secondary or tertiary hyperparathyroidism (HPT) reported in up to 30%-50% of renal transplant patients can cause osteitis fibrosa cystica a form of high turnover bone disease[4]. (exposed-skin-care.net)
  • Our Bone Marrow Transplant Program has revolutionized the care of patients requiring blood or marrow transplants through many novel advancements including mismatched transplants and outpatient care of bone marrow transplantation. (hopkinsmedicine.org)
  • Researchers at Johns Hopkins performed a half-match bone marrow transplant. (hopkinsmedicine.org)
  • Our clinic provides telemedicine services for patients undergoing bone marrow transplantation and transplant recipients. (hopkinsmedicine.org)
  • When a patient needs a transplant, we will search for a donor with the same tissue type as the patient. (oslo-universitetssykehus.no)
  • We conduct research to improve transplant outcomes provide support and resources for patients, and partner with a global network. (bethematch.org)
  • Learn how marrow donation works, the steps of a patient transplant, steps of donation, and factors that can impact the likelihood of finding a match. (bethematch.org)
  • The drug of choice for prevention of CMV disease in solid-organ transplant patients is valganciclovir. (medscape.com)
  • Methods Center for International Blood and Marrow Transplant Research data from 184 adults who completed the Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) before undergoing alloHCT and at day 100 were used. (cdc.gov)
  • Regret was measured using a FACT-BMT item not included in scoring: "I regret having the bone marrow transplant. (cdc.gov)
  • Sputum testing should include Gram stain, mycobacterial and fungal stains and cultures, and sometimes testing for viruses (eg, polymerase chain reaction for cytomegalovirus in a transplant patient or in a patient with AIDS). (msdmanuals.com)
Cellular Therapy2
  • Welcome to the Blood and Marrow Transplantation & Cellular Therapy Division. (stanford.edu)
  • Since 2007, the program has trained more than 45 physicians with majority of our graduates now working in the field of transplantation and cellular therapy throughout the country. (stanford.edu)
Severe8
  • In human patients who receive bone marrow transplants, GVHD can cause severe gut damage from donor cells attacking host cells. (oncologynurseadvisor.com)
  • We constructed a Markov model to simulate the 10-year clinical course of patients aged 21-40 years with newly diagnosed severe aplastic anemia . (bvsalud.org)
  • BMT and IST produced similar QALY for young patients with severe aplastic anemia . (bvsalud.org)
  • The survival of patients suffering from severe LADI is discussed in this paper. (najah.edu)
  • The approach is to do bone marrow transplantation as soon as possible, however, we report 4 patients suffering from severe LADI, who did not have bone marrow transplantation. (najah.edu)
  • Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematological disorder characterized by complement-mediated intravascular hemolysis, bone marrow failure, and severe thrombophilia ( 1 ). (frontiersin.org)
  • patients with severe chronic neutropenia. (drugs.com)
  • Participants 96 consecutively admitted patients with laboratory confirmed SARS-CoV-2 infection: 22 with mild disease and 74 with severe disease. (bmj.com)
20002
Donor13
  • In contrast to the expected mixed chimerism that usually occurs in the absence of conditioning, we found in our patients 100% donor cell engraftment based on fluorescence in situ hybridization (FISH) and microsatellite techniques. (nih.gov)
  • Subset analysis of the engrafted cells using a multiparametric system enabling a combined analysis of morphology, immunophenotyping and FISH showed that both T and B lymphocytes and myeloid cells were of donor origin in two patients, while T lymphocytes and myeloid cells were of donor origin in the third. (nih.gov)
  • Multilineage donor engraftment is possible in SCID patients even without conditioning. (nih.gov)
  • Allogeneic bone marrow transplantation (BMT) from an HLA-matched sibling donor is recommended as an initial treatment for young patients . (bvsalud.org)
  • In practice, however, a compatible donor can be found for less than 30% of patients, and the success rate of the intervention depends on their age and the quality of clinical management they have received throughout their lives. (who.int)
  • While the graft-versus-tumor effect provided by the donor graft can be very powerful in controlling the disease, disease relapse is still the primary reason that patients do not do well after an allogeneic transplantation. (stanford.edu)
  • Do you want to become a bone marrow donor? (oslo-universitetssykehus.no)
  • Registration as a bone marrow donor also takes place in the blood bank. (oslo-universitetssykehus.no)
  • This is an English translation of the recruitment and consent brochure published in Norwegian by The Norwegian Bone Marrow Donor Registry (NBMDR), Department of Immunology, Oslo University Hospital. (oslo-universitetssykehus.no)
  • After you have been tissue typed, your data will be entered into the database of The Norwegian Bone Marrow Donor Registry. (oslo-universitetssykehus.no)
  • If a sister or a brother has the same tissue type as the patient, she or he will be the best donor. (oslo-universitetssykehus.no)
  • If the patient does not have a sibling or other close relatives with the same tissue type, one will need to search for an unrelated donor with the same tissue type as the patient. (oslo-universitetssykehus.no)
  • First, the bone marrow donor receives full anaesthesia. (oslo-universitetssykehus.no)
Malignancies1
  • recipients constituted 42% of those patients, while underlying malignancies were found in 26% (Table 1). (who.int)
PBSCT1
  • We conclude that in spite of rapid engraftment, non-hematological toxicities and infections remain important limitations for further reduction of the length of patient hospitalization in a significant number of patients after PBSCT. (nature.com)
Disorders5
  • The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. (nih.gov)
  • We provide advanced treatments for a variety of cancer and blood disorders for any patient. (hopkinsmedicine.org)
  • Our multidisciplinary program collaborates with Johns Hopkins Sidney Kimmel Comprehensive Cancer Center and Children's Center to potentially cure children with a variety of cancers and other disorders of the blood, immune system and bone marrow. (hopkinsmedicine.org)
  • Most of the patients suffer from leukaemia (blood cancer) or other serious blood diseases, but patients with certain rare inborn metabolic disorders, inborn immunodeficiencies or extensive irradiation damage may also be treated. (oslo-universitetssykehus.no)
  • In general, transplantation yields the best results when performed early in the course of the disease (ie, in an asymptomatic affected sibling of a child with a lysosomal storage disorder), in centers with experience in performing transplantations to treat inherited metabolic disorders, and in patients healthy enough to tolerate the conditioning and transplantation regimen. (medscape.com)
Relapse after allogeneic1
  • Since approximately 30% of leukemia patients relapse after allogeneic BMT using total body irradiation (TBI)-based preparative regimens, treatment intensity may be suboptimal. (nature.com)
Chronic3
  • in humans they appear to occur 60-year-old man who had chronic lymphocytic leukemia predominantly in patients who have chronic granulomatous and in whom cerebral aspergillosis later developed and disease (CGD), a rare disorder of phagocytes in which the was confi rmed by biopsy. (cdc.gov)
  • When a patient is diagnosed with a blood cancer or chronic blood condition, it is often the start of a new journey that will be the beginning of great change. (rochester.edu)
  • In general, young patients have the most rapidly progressive disease, whereas patients with adult onset experience a more chronic and insidious progression of disease. (medscape.com)
Outcome2
  • As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein. (drcalapai.com)
  • We report here on the long-term outcome of all patients treated with HDM/ASCT for AL amyloidosis in Sweden between 1994 and 2009. (lu.se)
Conditioning regimens1
  • One hundred patients (receiving 123 conditioning regimens) were included in the analysis. (nature.com)
Diseases3
  • Psychology of cancer patients, their families and nursing personal Informing patients about their malignant diseases. (muni.cz)
  • Aetiology of cancer, influence of nutrition on cancer development, nutrition of oncology patients Pharmacotherapy of malignant diseases and adverse effects of these drugs- Radiotherapy of malignant diseases, adverse effects of radiotherapy Basic information's about most frequent cancer diseases Urological cancer Digestive tract cancer Lung cancer Gynaecologic cancer Bone marrow transplantation, indication, methods, results. (muni.cz)
  • Bone Marrow Transplantation is a common therapy to cure some forms of cancer and other diseases. (hopkinsmedicine.org)
Common complication1
Cells7
  • In conclusion, genomic DNA isolation in patients undergoing BMT should be done frompatients' own cells. (istanbul.edu.tr)
  • The goal of this clinical trial is to compare the effectiveness of unseparated whole blood (referred to as Low-Titer Group O Whole Blood) and the separate components of whole blood (including red cells, plasma, platelets, and cryoprecipitate) in critically injured patients who require large-volume blood transfusions. (nih.gov)
  • Patients with thalassaemia need regular transfusions of red blood cells (once or twice monthly) in order to maintain a mean haemoglobin concentration of about 9.0-10.5 g/dl. (who.int)
  • Experiments in cells cultured from the patients suggested that ADA2 deficiency interferes with the body's balance of white blood cells called monocytes and macrophages. (nih.gov)
  • Although longitudinal natural history data are limited, published guidelines are available to assist with decisions related to the pursuit of transplantation and whether to use bone marrow or umbilical cord blood-derived cells. (medscape.com)
  • 15]. The percentage of bone common of which are trisomy 8, mono- marrow blast cells for estimation of the Myelodysplastic syndrome (MDS) is somy 7 and 5q- [11]. (who.int)
  • All patients can evolve into trisomy 8+ MDS [12], cells, since acquiring adequate samples diagnosed with MDS have a reduced in which 8+ appears to confer a favour- for flow cytometric analysis renders the life expectancy compared with age- able prognosis [13]. (who.int)
Recurrent3
  • A second patient 2 years ago had similar symptoms, including recurrent fevers and 6 strokes by her sixth birthday. (nih.gov)
  • Patients with PID have increased susceptibility to recurrent and persistent infections, but other symptoms are also common. (lu.se)
  • PID patients have recurrent, serious infections starting early after birth. (lu.se)
Underwent3
  • The present report describes an incomplete atypical femoral fracture (AFF) patient who underwent simultaneous autogenous bone transplantation to the resected fracture region during intramedullary nail fixation. (hindawi.com)
  • Participants included 38 patients who underwent primary allogeneic bone marrow transplantation. (magiran.com)
  • Conclusions: Among patients who underwent alloHCT and lived to 100 days, the majority did not report regretting their transplantation. (cdc.gov)
Centers1
  • The team next sequenced CECR1 from 4 patients from other centers who had symptoms of the syndrome. (nih.gov)
Underlying bone marrow1
  • Different factors contribute to residual anemia during eculizumab treatment: underlying bone marrow dysfunction, residual intravascular hemolysis and the emergence of C3-mediated extravascular hemolysis. (frontiersin.org)
Survivors2
  • The aim of this prospective study was to describe the changes in the occupational status of 62 Bone Marrow Transplantation (BMT) survivors, comparing three groups: G1 (up to 18 months after the BMT), G2 (from 19 to 48 months after the BMT) and G3 (from 49 to 120 months after the BMT). (bvsalud.org)
  • This protocol is about a meta-analysis which will systematically report the simultaneous effects of dietary intervention or physical activity with cognitive-behavioral therapy, or three of them on quality of life, the recurrence levels and anthropometric measurements among patients with breast cancer and survivors. (magiran.com)
Metabolic1
  • It really is associated with lack of cancellous bone tissue and abnormal nutrient metabolic activity. (exposed-skin-care.net)
Transplants3
Outcomes1
  • In the current study, the authors investigated whether patients expressed regret after undergoing HCT and the relationships between clinical outcomes and quality of life. (cdc.gov)
20231
  • Dr. Appelbaum is the Executive Vice President and Clinical Research Professor at Fred Hutch Cancer Center (Seattle, WA) and author of " Living Medicine: Don Thomas, Marrow Transplantation, and the Cell Therapy Revolution " (2023). (iwmf.com)
Questionnaires1
  • Screening questionnaires to assess psychological distress in cancer patients are well-established, but in practice there are difficulties in implementation screening up to referral to psycho-oncology. (frontiersin.org)
Cortical bone3
  • After the fixation, the cortical bone at the fracture region was excised as a wedge-shaped block, and bone marrow extracted from the hollow reamer was simultaneously transplanted to the resected fracture region. (hindawi.com)
  • Histological examination showed few bone formation features at the fracture line in the excised lateral cortical bone. (hindawi.com)
  • It is associated with cortical bone loss and weakening its mechanical function[5]. (exposed-skin-care.net)
Blood11
  • This phase II trial studies how well xisomab 3G3 works in preventing catheter-associated blood clots (thrombosis) in patients with cancer receiving chemotherapy. (nih.gov)
  • Many patients with cancer develop blood clots from their catheters and can have pain, swelling, and other symptoms. (nih.gov)
  • This study is looking at how well oral anticoagulation medicines work to prevent complications, such as blood clots and heart attack, for patients who experience post-operative atrial fibrillation (POAF). (nih.gov)
  • Complete normalization of hemoglobin (complete and major hematological response), is seen in no more than one third of patients, while the remaining continue to experience some degree of anemia (good and partial hematological responses), in some cases requiring regular red blood cell transfusions (minor hematological response). (frontiersin.org)
  • A new study challenges long-held theories of why a common virus -- cytomegalovirus, or CMV -- can reactivate and become a life-threatening infection in people with a compromised immune system, including blood cancer patients undergoing bone marrow transplantation. (sciencedaily.com)
  • In this episode, the doctors delve into what Minimal/Measurable Disease (MRD) is, which blood cancers testing is currently used on, and how we can utilize it to more accurately monitor patients and customize treatment. (stanford.edu)
  • The patients' immune systems attack their own blood vessels, resulting in damaging inflammation that can cause strokes and other blood vessel-related problems. (nih.gov)
  • In an accompanying paper, an Israeli research group reported variants of the same gene in patients with a similar type of blood vessel inflammation. (nih.gov)
  • In Norway new bone marrow donors are only recruited among blood donors. (oslo-universitetssykehus.no)
  • The bone marrow, which looks like blood, is aspirated through the needle to be collected in a transfusion bag. (oslo-universitetssykehus.no)
  • Patients receiving granulocyte components, components that are HLA matched, or directed donations (from blood relatives) . (utmb.edu)
Patient's1
Methods2
  • Design and Methods Oral cyclophosphamide, thalidomide, and dexamethasone was compared with infusional cyclophosphamide, vincristine, doxorubicin, and dexamethasone in patients with newly diagnosed multiple myeloma. (haematologica.org)
  • Future work should explore regret in other patient groups and use qualitative methods to inform best practices for reducing regret. (cdc.gov)
Diagnosis4
  • In Germany, for example, this is supported by the S3 guideline Psychooncological Diagnosis and Treatment of Cancer Patients ( 8 ) and the guidelines of the National Cancer Center Network ( 9 ). (frontiersin.org)
  • In some immunocompromised patients, who shed the virus for long periods, the diagnosis can be of little clinical significance. (medscape.com)
  • unreliable and unavailable commercially in most of the world [ 1 ], thus evaluation of A total of 19 patients were identified as appropriate specimens by smear and culture having a culture-proven diagnosis of remains the principal method of diagnosis. (who.int)
  • Although progression is typically less rapid than in the infantile form, death usually occurs within 10-15 years of diagnosis, and most patients die before age 20 years. (medscape.com)
Antibody1
  • Patients with antibody deficiencies are especially susceptible to encapsulated bacteria, which cause pyogenic infections. (lu.se)
Infection5
  • While the spread of chromoblastomycosis to the muscle and bone is usually rare, in cases where antifungal drugs alone are insufficient in controlling the dissemination of the infection, limb amputation is required. (wikipedia.org)
  • Based on its oral administration and the reduced incidence of infection and cytopenia, cyclophosphamide-thalidomide-dexa-methasone may be considered an effective induction therapy option for patients with newly diagnosed multiple myeloma. (haematologica.org)
  • Most patients with CMV infection exhibit few clinical findings on physical examination. (medscape.com)
  • In patients with HIV infection, CMV involves the entire GI tract. (medscape.com)
  • A total of 19 patients were identified as having culture-proven nocardial infection. (who.int)
Complications2
  • In 31 patients (25%) delayed discharge was due to complications: in 14 patients (11.4%) because of GIT problems, in 16 patients (13%) because of infectious complications and in one patient because of cardiotoxicity. (nature.com)
  • Complications from bone disease not only cause significant morbidity but also increase the cost of care hospitalization and mortality[1-3]. (exposed-skin-care.net)
Treatment11
  • Indeed, the hematological benefit during eculizumab treatment for PNH is very heterogeneous among patients, and different response categories can be identified. (frontiersin.org)
  • All but one patient developed treatment-related grade 3 or 4 mucositis. (nature.com)
  • The present study examines QoL in a large number of patients 1 year from the end of treatment within the United Kingdom Medical Research Council (UK MRC) AML10 trial of BMT versus CCT. (ox.ac.uk)
  • Thus, there is a clear need to provide more information about psycho-oncology services and to be able to offer psycho-oncological treatment to patients who need it. (frontiersin.org)
  • WYE-687 Successful avoidance of bone tissue loss has been proven with WYE-687 vitamin D bisphosphonates calcitonin as well as treatment of hypogonadism and HPT. (exposed-skin-care.net)
  • The avoidance and treatment of adynamic bone tissue disease is normally avoidance of over suppression of PTH secretion. (exposed-skin-care.net)
  • Many patients receiving this combined treatment are now well into their thirties or forties, and in high-income countries life expectancy is steadily rising towards normal values. (who.int)
  • We develop personalized, comprehensive treatment plans for all our patients, offering the latest therapies and supportive resources, and taking your particular needs into account. (dana-farber.org)
  • You may withdraw at any time before the pre-treatment of the patient starts, and you do not need to give a reason. (oslo-universitetssykehus.no)
  • PID patients require prolonged treatment with high doses. (lu.se)
  • In SCIDs bone marrow transplantation is the most effective treatment. (lu.se)
Leukemia3
  • Bone marrow is transplanted primarily in leukemia. (dnatube.com)
  • Stanford Medicine's Lori Muffly, MD and Matthew Frank, MD, PhD from Stanford Medicine in Stanford, CA, were recently featured on The Bloodline with LLS, the podcast by The Leukemia & Lymphoma Society (LLS) for patients and caregivers. (stanford.edu)
  • Absence of FLT3 mutations in Iranian adult T-cell leukemia/lymphoma patients. (cdc.gov)
Cyclophosphamide1
  • A trend toward an overall survival advantage for cyclophosphamide-thalidomide-dexamethasone over cyclophosphamide-vincristine-doxorubicin-dexamethasone was also observed in a subgroup of patients with favorable interphase fluorescence in situ hybridization. (haematologica.org)
Adult4
  • Decision analysis of allogeneic bone marrow transplantation versus immunosuppressive therapy for young adult patients with aplastic anemia. (bvsalud.org)
  • One unit of RBCs in an adult and 10mL/Kg in a pediatric patient will increase the hematocrit by approximately 3% or the hemoglobin by 1 g/dL in a normovolemic patient. (utmb.edu)
  • Patients with the adult form may have an even slower progression than those with the late juvenile form. (medscape.com)
  • Rarely, patients with the adult form may present with choreiform movements, dystonia, or both. (medscape.com)
Psychological3
  • What if… I Asked Cancer Patients About Psychological Distress? (frontiersin.org)
  • In addition, ~50% experience psychological distress, and 30% of patients develop a mental disorder during the course of the disease ( 4 ). (frontiersin.org)
  • Psychological problems of cancer patient. (muni.cz)
Donors1
  • All patients had HLA-identical sibling donors. (nature.com)
Biopsy3
  • Bone biopsy characteristically shows increased bone resorption considerable osteoclastic activity and endosteal fibrosis[6]. (exposed-skin-care.net)
  • it is usually caused by over-suppression of PTH and various other growth elements[8 10 11 Bone tissue biopsy findings add a low bone tissue formation price as evaluated by tetracycline WYE-687 fluorescence-labeling little if any mobile activity (paucity of osteoblasts and osteoclasts) and slim osteoid seams[6]. (exposed-skin-care.net)
  • Osteomalacia Osteomalacia is definitely characterized by a deficit in bone mineralization due to hypophosphatemia malnutrition vitamin D deficiency or aluminium toxicity[11 12 Characteristic findings on bone biopsy include wide unmineralized osteoid seams low bone formation absence of osteoblasts and osteoclasts[6]. (exposed-skin-care.net)
Cancer Center1
  • Our program collaborates with specialists at the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins Children's Center for the best quality of care for all patients. (hopkinsmedicine.org)
Edema3
  • Coronal STIR image showing focal cortical thickening with minimal edema of the adjacent bone marrow (b). (hindawi.com)
  • Objective To determine the effectiveness of standardized manual lymphatic drainage in reducing facial edema, interincisal distance and pain after alveolar bone grafting surgery in patients with cleft lip and palate. (bvsalud.org)
  • Conclusion The proposed manual lymphatic drainage procedure provided significant reduction in facial edema reduction, in pain, and interincisal distance increase, reinforcing the hypothesis that this technique was effective in accelerating the recovery of patients with cleft lip and palate undergoing alveolar bone grafting surgery. (bvsalud.org)
Normal bone1