• outcomes for patients
  • Disease management (DM) programs provide a systematic approach to optimizing care and outcomes for patients with heart failure (HF), the treatment of which is often complicated by one or more coexisting conditions, polypharmacy, psychosocial factors, health literacy issues, and economic concerns. (oncologynurseadvisor.com)
  • therapeutic
  • Accurate preprocedural evaluation of patients who are candidates for TAVI is mandatory to plan the most adequate therapeutic approach and to select the prosthesis size. (bmj.com)
  • Even so, in the progress reports sent to the DOD and in his testimony to the Subcommittee on Administrative Law and Governmental Relations in 1994, Dr. Saenger maintained that the primary goal of the study was to provide palliative and therapeutic care to the patients. (wikipedia.org)
  • undergo
  • And both of these changes-less invasive alternatives and new medical adjuncts-have influenced which patients undergo, and garner benefit from carotid revascularization [ 13 , 14 ]. (hindawi.com)
  • While laparoscopy itself may be the prime mode of detection and confirmation of malignancy, more often patients who undergo laparoscopic examination have had a previous histologic confirmation by gastrointestinal endoscopic techniques or peripheral node biopsy. (barnardhealth.us)
  • therapies
  • The selection of patients for tumor-specific therapies using molecular/biological properties of the patient's tumor has been a long tradition in breast cancer (e.g., estrogen receptor, progesterone receptor, and HER-2/ neu ) but has not been widely accepted in lung cancer therapy selection ( 1 , 2 ). (aacrjournals.org)
  • Active surveillance (AS) or watchful waiting is a management option for localized prostate cancer that can be offered to appropriate patients who would also be candidates for aggressive local therapies (surgery and radiotherapy), with the intent to intervene if the disease progresses. (wikipedia.org)
  • Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS. The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. (wikipedia.org)
  • chemotherapy
  • For example, a randomized trial comparing chemotherapy alone to chemotherapy with erlotinib, EGFR -mutated patients had a superior outcome regardless of the therapy ( 19 ). (aacrjournals.org)
  • PML occurs almost exclusively in patients with severe immune deficiency, most commonly among patients with acquired immune deficiency syndrome (AIDS), but people on chronic immunosuppressive medications including chemotherapy are also at increased risk of PML, such as patients with transplants, Hodgkin's lymphoma, multiple sclerosis, psoriasis and other autoimmune diseases. (wikipedia.org)
  • Reports from several large retrospective patient series suggest that it has a 5-year overall survival rate (5y OSR) averaging 30 to 40% and a 10y OSR around 16%, whereas the highest 5y OSR for modern chemotherapy regimens is only 9% (with FOLFOX). (wikipedia.org)
  • complications
  • Conclusions- Exclusion of single patients on the basis of risk modeling may be problematic when the rate of perioperative complications is very low. (ahajournals.org)
  • However, now more than ever surgeons must balance the potential benefits associated with these interventions with the risks of physiologic insult for these elderly patients, who often have significant comorbidity burdens and the potential for costly complications. (hindawi.com)
  • In this paper, we highlight how regional and national datasets can help surgeons identify which patients are most likely to benefit from vascular operations and which patients are most likely to suffer complications in the postoperative period. (hindawi.com)
  • One of the most important elements in effectively utilizing expensive, morbid procedures, such as thoracic aneurysm repair, lower extremity bypass, and carotid endarterectomy, is to perform these procedures on patients who will benefit from the procedure and not suffer complications from it. (hindawi.com)
  • The study compared more than 8,500 propensity-adjusted patients and revealed that EVH significantly reduced wound complications without compromising long-term survival or freedom from repeat revascularization. (wikipedia.org)
  • While DBS has proven to be effective for some patients, potential for serious complications and side effects exists. (wikipedia.org)
  • candidates
  • So while there are standard exclusion criteria for some forms of organ transplant -- for example, a patient in need of a liver may be denied a spot on the UNOS waiting list if he cannot abstain from alcohol for six months before surgery -- there are currently no such restrictions for face transplant candidates. (go.com)
  • In patients with significant cardiac and respiratory disease who would not be candidates for open abdominal procedures because of the requirements for general anesthesia, laparoscopy may in fact prove hazardous because of the need for both general anesthesia and a significant pneumoperitoneum. (barnardhealth.us)
  • radiation
  • The Cincinnati Radiation Experiments were a series of total and partial body irradiation tests performed on at least 90 patients with advanced cancer at the Cincinnati General Hospital, now University Hospital, from 1960-1971. (wikipedia.org)
  • On September 25, 1958, Saenger sent a grant proposal entitled "Metabolic Changes in Human following Total Body Radiation" to the Department of Defense, requesting $25,085 to analyze the amino-aciduria levels in the urine of total body irradiated patients. (wikipedia.org)
  • Although they were all cancerous, Dr. Saenger sought patients that were in good nutritional health, and who had not been exposed to previous radiation treatment. (wikipedia.org)
  • David Egilman, a doctor practicing in Massachusetts at the time, criticized the patient selection and irradiation processes in a statement to the Advisory Committee on Human Radiation Experiments, writing that many of the cancers were radio-resistant and could not have been treated effectively without killing the patient. (wikipedia.org)
  • This means many fewer repeated scans, which reduces costs and also reduces patient exposure to radiation. (wikipedia.org)
  • patient's
  • Cardiac pumps are most often used in heart surgery, so that a patient's heart can be disconnected from the body for longer than the twenty minutes or so it takes for a prepared patient to die. (wikipedia.org)
  • A counter-argument against the prevailing view concerning the younger years is that it may actually be quicker and easier to restrengthen an older patient's musculature and regaining of walking may happen faster with an older patient due to the fact that the patient is fully matured and very aware of what is going on, and so may work harder and with more focus than might a young child. (wikipedia.org)
  • By 1991, the first pregnancy was recorded using IVM followed by IVF, and in 1994 the first birth using IVM oocytes from polycystic ovarian syndrome patients was recorded highlighting that PCOS patient's oocytes are capable of maturation. (wikipedia.org)
  • procedure
  • But as the number of successful face transplant surgeries inches ever higher, medical ethicists already are discussing how to make decisions on if and when patients should be eligible for the costly and complex procedure that some say represents the ultimate gift from a deceased donor's family. (go.com)
  • Every physician-endoscopist undertaking laparoscopy should have a clear understanding of the benefits offered by the procedure and should be willing to recommend avoidance of the technique if there is no defineable gain for the patient. (barnardhealth.us)
  • In patients with ascitic collection from both cirrhosis and hepatoma for instance, (Fig. 3.4) these coagulation problems must be corrected with fresh frozen plasma or vitamin K prior to any diagnostic procedure. (barnardhealth.us)
  • In any patient with ascitic collections, a thorough history and physical examination are required to evaluate a patient for diagnostic laparoscopy and should be prerequisites to determine the appropriateness of this procedure. (barnardhealth.us)
  • During the awake procedure with local anesthesia, feedback from the patient is used to determine the optimal placement of the permanent electrode. (wikipedia.org)
  • At present, the procedure is used only for patients whose symptoms cannot be adequately controlled with medications, or whose medications have severe side-effects. (wikipedia.org)
  • surgery
  • This means that preventive surgery remains without benefit for at least 4 of 5 operated patients. (ahajournals.org)
  • They must consider, against the background of medical alternatives, the physiologic insult that surgery entails in these elderly patients, who often carry with them significant comorbidity burdens [ 7 - 10 ]. (hindawi.com)
  • Accurate estimates of benefits and risks of aortocoronary bypass surgery are necessary in the management of specific patients. (ahajournals.org)
  • Totaling more than 16,000 patients tracked, these three studies provide strong evidence that EVH is a safe and viable technique to use to obtain a saphenous vein conduit for CABG surgery. (wikipedia.org)
  • Surgery is the mainstay of treatment for patients with isolated lung metastasis from colorectal cancer. (wikipedia.org)
  • Treatment
  • The development of a patient selection strategy linked to target expression on the tumor is thus critically important for identifying the population appropriate for receiving treatment," the two conclude. (prweb.com)
  • Although an ADC like anetumab ravtansine appears to offer new hope for mesothelioma treatment, this article reminds us that these drugs are only effective in the right patients and may be a waste of time and resources for others," says Alex Strauss, Managing Editor for Surviving Mesothelioma. (prweb.com)
  • In patients who present with as-cites, the opportunity for curative resection becomes less although appropriate treatment strategies may be undertaken if the etiology of the ascitic fluid becomes known. (barnardhealth.us)
  • In the meantime, active surveillance for the treatment of low risk prostate cancer is now being offered to more and more patients where it is generally considered that prostate cancer will not cause the man harm during his lifetime if treatment is delayed or avoided. (wikipedia.org)
  • Dr. Saenger maintained that while the DOD funds were used to buy irradiation equipment, run laboratory tests, and hire personnel, only University funds directly financed the patients' irradiation treatment. (wikipedia.org)
  • In the European Union, it has been approved for human use only for the treatment of multiple sclerosis and only then as a monotherapy because the initial cases of PML, and later the fatalities, were said by the manufacturers to be linked to the use of previous medicines by the patients. (wikipedia.org)
  • Natalizumab may be appropriate in patients who do not respond to medications that block tumor necrosis factor-alpha such as infliximab, with some evidence to support combination treatment of Crohn's disease with natalizumab and infliximab may be helpful in inducing remission. (wikipedia.org)
  • survival
  • Some large phase II trials in Caucasian patients failed to show a significant association between EGFR mutations and survival ( 25 , 26 ). (aacrjournals.org)
  • Patients with early-stage lung cancer and with a positive EGFR test have a superior survival compared with patients with a negative test. (aacrjournals.org)
  • Methods
  • In order to establish a safe pneumoperitoneum in a patient with a previously operated abdomen, open techniques using a Hasson cannula and adjunctive methods using ultrasound have been recommended to avoid inappropriate trocar placement. (barnardhealth.us)
  • liver
  • But even now, as the world's total number of face transplant recipients stands at six, it is clear that there are differences when it comes to determining whether a patient is a viable candidate for a new face, as opposed to a liver, heart or other organ. (go.com)
  • Of patients who die from metastasised colorectal cancer, 20% have metastasis in the liver alone. (wikipedia.org)
  • Some have argued that the excellent results of liver metastasectomy for colorectal cancer are partially confounded by selection bias or reporting bias. (wikipedia.org)
  • Previously, liver metastasectomy was limited to patients with less than four sites of metastasis in the liver, with a tumour-free margin of at least 1 centimetre, and no cancer elsewhere. (wikipedia.org)
  • malignant
  • Researchers with a company that makes antibody-based immunotherapy drugs are calling for the development of new patient selection strategies for people with malignant mesothelioma and other intractable cancers. (prweb.com)
  • As the skill of the endoscopist increases, patients having previous operations for both benign and malignant processes may be approached, especially to satisfy the need for a 'second look' rather than a formal celiotomy. (barnardhealth.us)
  • disease
  • In patients with valvular heart disease, murmurs suggestive of aortic or mitral stenosis or regurgitation or tricuspid regurgitation may be present. (oncologynurseadvisor.com)
  • The outcomes of men who are not treated for prostate cancer is dependent on cancer grade (the higher the grade the more aggressive), the life expectancy of the patient with the disease, and whether or not the cancer was detected through screening. (wikipedia.org)
  • For patients with coronary artery disease, a physician may recommend a bypass to reroute blood around blocked arteries to restore and improve blood flow and oxygen to the heart. (wikipedia.org)
  • Other benefits of natalizumab use by patients with relapsing MS included reduced visual loss, a significant increase in the proportion of disease-free individuals, significantly improved assessments of health-related quality of life in relapsing individuals, reduced cognitive decline of a portion of individuals with MS, reduced hospitalizations and steroid use, and prevention of the formation of new lesions. (wikipedia.org)
  • Several randomized controlled trials have demonstrated that natalizumab is effective in increasing rates of remission and maintaining symptom-free status in patients with Crohn's disease. (wikipedia.org)
  • awake
  • Diagnostic laparoscopy in the assessment of ascites or peritoneal malignancy may be undertaken using general anesthetic techniques or local infiltration with intravenous sedation in the awake patient. (barnardhealth.us)
  • facial
  • Rather, facial transplant patients are largely selected by a process of elimination -- those patients for whom other surgeries have not worked. (go.com)
  • results
  • citation needed] There are few sites in the brain that can be targeted to achieve differing results, so each patient must be assessed individually, and a site will be chosen based on their needs. (wikipedia.org)
  • effectiveness
  • However, recent cases of successful SDR procedures among those with spastic diplegia across all major age ranges (years 3-40 and even above) has finally proven its universal effectiveness and safety regardless of the age of the spastic diplegic patient. (wikipedia.org)
  • select patients
  • To best select patients for these high-risk operations, surgeons need data that incorporates these complex covariates in their decision-making algorithms. (hindawi.com)
  • The epidermal growth factor receptor (EGFR) is an excellent target for lung cancer therapy, and it should be possible to select patients based on their expression of the EGFR gene, EGFR protein, or related genes and proteins ( 3 ). (aacrjournals.org)
  • natalizumab
  • As of May 2011, over 130 cases of PML had been reported in MS patients, all in patients who had taken natalizumab for more than a year. (wikipedia.org)
  • Natalizumab also slowed the progression of disability in patients with relapsing MS. In combination with interferon beta-1a (IB1A), relapsing and disability progression were reduced more than IB1A alone. (wikipedia.org)
  • Assessment
  • Selection of patients and the technique utilized for laparoscopy in the assessment of patients with ascites and potential peritoneal malignancy depend heavily on the information to be gained from the study. (barnardhealth.us)
  • The full assessment of these patients must be performed using a complement of laparoscopy and imaging techniques since the laparoscope is only able to visualize surface lesions, even though these implants may be quite small. (barnardhealth.us)
  • stroke
  • 1-4 Provided that no major complication occurs during the operation, most patients find themselves efficiently protected against stroke in the following years. (ahajournals.org)
  • Accurate
  • This process is not, however, considered accurate in the evaluation of pathologies affecting the central part of the retina (macula and fovea centralis) patients with these pathologies are often unable to fixate reliably. (wikipedia.org)
  • diagnostic
  • As discussed in more detail below, imaging studies, especially echocardiography, play a prominent role in the diagnostic evaluation of patients with suspected HF. (oncologynurseadvisor.com)
  • While small laparoscopic cameras and instrumentation have become available for utilization outside the operating room setting , patients undergoing diagnostic lap-aroscopy may also need immediate celiotomy as the next step in full diagnosis or therapy. (barnardhealth.us)
  • medical
  • and the irradiation was administered all at once, which diverged from the standard medical practice at the time, where cancer patients were given small doses cumulatively to maximize destruction of cancer cells. (wikipedia.org)
  • On the other hand, the American College of Radiology, after sending representatives to Dr. Saenger's laboratory during the irradiation experiments, concluded in a 1972 peer review that the patient selection process and the experiments as a whole "conformed with good medical practice. (wikipedia.org)
  • care
  • Cardinal features of DM include patient and family education, emphasis on self-care, and close follow-up, especially during and after care transitions (e.g., hospital to home). (oncologynurseadvisor.com)
  • SOAR's goal is to examine quality, delivery, and financing of care in order to have an immediate impact on patient care and system improvements. (wikipedia.org)
  • Outcomes Research evaluates the impact of health care on the health outcomes of patients and populations (see AHRQ for further details). (wikipedia.org)
  • The information learned can have an immediate impact on patient care and system improvement. (wikipedia.org)
  • study
  • The most sophisticated study is videourodynamics, the criterion standard in the evaluation of a patient with incontinence. (medscape.com)
  • The experiments were conducted without patient consent in the first five years of the study and with disputed levels of consent thereafter. (wikipedia.org)