• A recent systematic review including 11 studies demonstrates consistent improvement in many outcome measures of patients, such as relapse rates and medication adherence, but heterogeneity in symptoms reliefs ( 9 ). (frontiersin.org)
  • In addition to evaluating the impact of treatment on individual patient-reported outcome (PRO) measures, MCIDs can be used in number needed-to-treat (NNT) or predictive analyses to better understand the magnitude of treatment benefit. (bmj.com)
  • The Index comprises a structured approach to Goal Attainment Scaling together with severity indicators and confounders to recovery, and a limited set of standardised measures determined by the selected goal areas of treatment for any given patient. (kcl.ac.uk)
  • Instruments such as Health Utilities Indexes, Short Forms, EQ-5Ds, and the PROMIS underscore patient reported outcome measures, otherwise known as PROMs- these documents were created to both validate and standardize the depth of patient care and well-being. (hubofarticles.com)
  • The patient-reported outcome measures documents are meant to be complete by patients themselves. (hubofarticles.com)
  • Clinically stable adult patients with unplanned admissions through the day and night under the care of general surgeons at two acute NHS trusts were approached during working week days and asked to complete validated PRO measures (European Quality of Life-5 Dimension, Short Form-12, and Gastrointestinal Quality of Life Index) on admission and 6 weeks following discharge. (biomedcentral.com)
  • PROs can be assessed using questionnaires known as patient-reported outcome measures (PROMs). (biomedcentral.com)
  • This increased clinical trial activity in vasculitis has been accompanied by the development and validation of new outcome measures - a challenging process for these complex, multiorgan system diseases. (jrheum.org)
  • Core sets of outcome measures include the domains of the illness under study considered crucial to assess in clinical trials. (jrheum.org)
  • The Patient-Reported Outcomes Measurement Information System (PROMIS) provides clinicians and researchers access to reliable, valid, and flexible measures of health status that assess physical, mental, and social well-being from the patient perspective. (wikipedia.org)
  • PROMIS measures are standardized, allowing for assessment of many patient-reported outcome domains-including pain, fatigue, emotional distress, physical functioning and social role participation-based on common metrics that allow for comparisons across domains, across chronic diseases, and with the general population. (wikipedia.org)
  • The PROMIS initiative develops and evaluates standard measures for key patient-reported health indicators and symptoms. (wikipedia.org)
  • Patient-reported measures such as pain, fatigue, emotional distress, and physical functioning complement clinical measures (e.g., x-rays and lab tests) by providing healthcare providers with information about what patients are able to do and how they feel. (wikipedia.org)
  • PROMIS measures are intended to assess the most common or salient dimensions of patient-relevant outcomes for the widest possible range of chronic disorders and diseases, thus they are "generic" measures vs. specific to given disease or condition. (wikipedia.org)
  • Background and aims Sensitive outcome measures to assess the efficacy of therapeutic interventions in patients with cystic fibrosis (CF) with mild lung disease are currently lacking. (bmj.com)
  • p=0.016), whereas other outcome measures such as spirometry and quality of life failed to reach statistical significance. (bmj.com)
  • 8 Therefore, more sensitive and easier measures of lung function are needed for clinical studies in younger patients with CF with mild disease. (bmj.com)
  • This book serves as a roadmap for the development and application of patient-reported outcome (PRO) measures, supporting beginners through to experts, as a practical guide. (nshealth.ca)
  • Nurses who are diligent about assessing for risk factors, incorporating fall prevention measures, and verbalizing to patients the rationales behind precautions that may seem excessive, will have the best outcomes for their patients. (nursetogether.com)
  • Having an open and direct conversation with the patient about the individual risk factors that increase their risk for falls as well as the safety measures in place will increase adherence to interventions. (nursetogether.com)
  • Measures included PROMIS-Fatigue SFs (7a, 8a, 4a), other PROMIS measures of RA symptoms, and selected patient reported outcomes including RAND-36 Vitality, Fatigue NRS, and patient global assessment of disease activity. (springer.com)
  • Two evidence-based genomic applications were used as examples of "interventions", including 1) universal tumor testing for Lynch syndrome (LS) in all individuals with newly diagnosed colorectal cancer, and 2) screening to identify family history associated with hereditary breast and ovarian cancer (HBOC) syndrome, accepting that the outcome measures may be applied to other genetic conditions. (cdc.gov)
  • The outcome measures enable establishment of baseline targets and recording of progress and impact at the population level. (cdc.gov)
  • Overall, 38 outcome measures and corresponding performance objectives were identified. (cdc.gov)
  • The list of performance objectives and outcomes measures is by no means complete. (cdc.gov)
  • MAIN OUTCOMES AND MEASURES: The primary outcome was pain -related function (Brief Pain Inventory [BPI] interference scale) over 12 months and the main secondary outcome was pain intensity (BPI severity scale). (cdc.gov)
  • A retrospective medical chart review was conducted for older patients with locally advanced ESCC who received anticancer therapy between January 2012 and December 2012 at 22 medical centers (including 10 university hospitals and 10 cancer-specific hospitals), participating institutions of the Japanese Esophageal Oncology Group. (biomedcentral.com)
  • According to a recent study by Shanker and colleagues published in the Journal of Medical Imaging and Radiation Oncology, in patients with melanoma brain metastases (melanoma BM), concurrent treatment with immunotherapy and stereotactic radiosurgery is associated with improved clinical and radiological outcomes. (medpagetoday.com)
  • 2,3 "To date, very few studies have used [Response Assessment in Neuro-Oncology] RANO-[brain metastases] BM criteria," the study authors noted in their paper. (medpagetoday.com)
  • Perform basic and advanced interventions as part of a treatment plan intended to mitigate the emergency, provide symptom relief, and improve the overall health of the patient. (cnm.edu)
  • Dr Johns is also a principal investigator in many clinical trials investigating the effects of disease or interventions on QoL of cancer patients. (nshealth.ca)
  • Of note, given the scale and impact of mood disturbance among patients with diabetes, evidence for psychological interventions that successfully treat depression and distress and, ideally, concurrently improve metabolic outcomes is limited. (diabetesjournals.org)
  • Several reasons exist to continue the search for psychotherapeutic interventions to improve mental and physical health outcomes among patients with diabetes. (diabetesjournals.org)
  • As in other areas of public health, progress in the field depends on the ability to measure the impact of programs on the delivery of services and interventions, and health outcomes. (cdc.gov)
  • Progress has been made in testing tuberculosis patients for HIV infection, but provision of co-trimoxazole prophylaxis and antiretroviral therapy, the two crucial interventions for HIV-positive tuberculosis patients, is about one third of that targeted in the Global Plan. (who.int)
  • Main outcome measure Our primary outcome was all-cause mortality within 6 years of follow-up. (bmj.com)
  • The primary outcome was patient 's quality of life during the first week after periapical surgery and the secondary outcomes were duration of surgery and healing outcome at 12-month follow-up. (bvsalud.org)
  • Therefore, we designed a study to test the effect of inhalation of HS in paediatric patients with CF with normal spirometry (FEV 1 ) using the LCI as the primary outcome measure. (bmj.com)
  • The primary outcome was the use of low tidal volume ventilation (LTVV) for the first 3 days of mechanical ventilation. (lu.se)
  • Methods A total of 619 patients with active RA were randomised to CZP 200 or 400 mg, or placebo plus methotrexate (MTX). (bmj.com)
  • Methods In a crossover trial, 20 patients with CF received 4 weeks of hypertonic saline (HS) and isotonic saline (IS) in a randomised sequence separated by a 4 week washout period. (bmj.com)
  • Methods: Among 107 patients with OLTs treated arthroscopically, only the patients older than 50 years (65 patients) were included in this study. (researchgate.net)
  • Methods and applications of PROs in clinical practice, including individual patient management and using PRO results from comparative studies. (mapi-trust.org)
  • Methods to engage patients, family members, and members of the general public in the process of PRO-related research, policy formulation, and clinical guidelines development, and the evaluation of the effects of such engagement. (mapi-trust.org)
  • Methods: In this pooled analysis we harmonised individual patient data from the ERICC, LUNG SAFE, PRoVENT, and PRoVENT-iMiC prospective observational studies, which were conducted from June, 2011, to December, 2018, in 534 ICUs in 54 countries. (lu.se)
  • However, it is unclear whether the CONUT score during hospitalization influences the functional outcomes of aSAH patients. (nature.com)
  • Design Secondary analysis of patients included in a previous randomised-controlled trial with a median follow-up of 6.1 years. (bmj.com)
  • Secondary outcomes were adverse clinical outcome defined as intensive care unit (ICU) admission, empyema and unplanned hospital readmission all occurring within 30 days after admission. (bmj.com)
  • They continued, "This study aimed to report outcomes according to RANO-BM criteria in a contemporary cohort of patients with melanoma BM, following treatment with SRS and IT and/or targeted therapy. (medpagetoday.com)
  • Adult RA patients were recruited from an online arthritis patient community and an observational cohort drawing from three academic medical centers. (springer.com)
  • Clinical outcomes from the observational cohort included swollen and tender joint counts (28), physician global assessment, and the RA Clinical Disease Activity Index (CDAI). (springer.com)
  • This cohort study analyzed AEs in more than 3,600 ICU patients and assessed the relationship between AEs and mortality. (ahrq.gov)
  • Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries. (ahrq.gov)
  • Conclusions NEWS provides additional prognostic information with regard to risk of ICU admission and complications and thereby improves traditional clinical-risk scores in the management of patients with CAP in the ED setting. (bmj.com)
  • When part of early palliative care, nutrition therapy improves cancer patients' quality of life and may prolong survival at a fraction of the costs of developing new drugs. (cambridge.org)
  • Schizophrenia is a chronic and severe mental disorder which has serious consequences for both the patient and caregivers. (frontiersin.org)
  • Pulmonary rehabilitation is an integral part of the clinical management and health maintenance of those patients with chronic respiratory disease who remain symptomatic or continue to have decreased function despite standard medical treatment. (medscape.com)
  • The American Thoracic Society and the European Respiratory Society adopted the following definition of pulmonary rehabilitation: Pulmonary rehabilitation is an evidence-based, multidisciplinary, and comprehensive intervention for patients with chronic respiratory diseases who are symptomatic and often have decreased daily life activities. (medscape.com)
  • Pulmonary rehabilitation aims to reduce symptoms, decrease disability, increase participation in physical and social activities, and improve the overall quality of life (QOL) for patients with chronic respiratory disease. (medscape.com)
  • Although the degree of airway obstruction or hyperinflation of chronic obstructive pulmonary disease (COPD) does not change appreciably with pulmonary rehabilitation, reversal of muscle deconditioning and better pacing enables patients to walk farther and with less dyspnea. (medscape.com)
  • Pulmonary rehabilitation programs include prevention, early recognition and treatment of morbidities, and inpatient, outpatient, and extended care of patients with chronic respiratory illness. (medscape.com)
  • The aim of the present study was to compare the evolution of pulmonary haemodynamics and of arterial blood gases in chronic obstructive pulmonary disease (COPD) patients with mild-to-moderate hypoxaemia, with or without sleep-related oxygen desaturation. (ersjournals.com)
  • Information gaps were associated with severity of illness, being significantly more common in patients who had serious chronic illnesses, those who arrived by ambulance, those who had visited the emergency department or had been in hospital recently, patients in monitored areas in the emergency department and older patients. (cmaj.ca)
  • As protoporphyrin is a lipophilic molecule that is excreted by the liver, EPP patients are at risk of cholelithiasis with obstructive episodes, and chronic liver disease that might evolve to acute liver failure. (orpha.net)
  • The book demonstrates the importance of PROs to patients with chronic disease and how such outcomes can assist clinicians in managing patients and monitoring their response to treatment in terms of both symptoms and impacts. (nshealth.ca)
  • Major depression is estimated to affect at least 12% of patients with diabetes ( 1 ), with subclinical mood symptoms and distress apparent in nearly one-third (31%) of those living with this chronic condition ( 2 ). (diabetesjournals.org)
  • Patients in MICs were younger, shorter and with a slightly lower body-mass index, more often had diabetes and active cancer, but less often chronic obstructive pulmonary disease and heart failure than patients from HICs. (lu.se)
  • Like other chronic illnesses, diabetes mellitus poses a wide range of problems for patients and their family members. (cdc.gov)
  • Eligible patients had moderate to severe chronic back pain or hip or knee osteoarthritis pain despite analgesic use. (cdc.gov)
  • Sociodemographic, symptom severity (PANSS) and medication adherence (MARS) from patients were assessed at baseline and relapse rates was recorded during the 12 months follow-up period. (frontiersin.org)
  • In our current study, 117 patients diagnosed with trHTN and performed with unilateral adrenalectomy were consecutively enrolled, demographic and medical information were documented for baseline data collection. (degruyter.com)
  • At baseline ( t 0 ), patients with sleep-related desaturation had a significantly higher daytime (mean±sd) arterial carbon dioxide partial pressure ( P a,CO 2 ) (44.9±4.9 mmHg versus 41.0±4.1 mmHg, p=0.001) whereas mean pulmonary artery pressure (mPAP) was similar in the two groups. (ersjournals.com)
  • We used regression models to study associations of baseline risk scores and outcomes with the area under the receiver operating curve (AUC) as a measure of discrimination. (bmj.com)
  • One area of challenge is capturing baseline patient-reported outcome (PRO) data. (biomedcentral.com)
  • Feasibility of PRO data collection was determined by the proportions of admitted patients eligible and recruited and by questionnaire-response rates at baseline and follow up. (biomedcentral.com)
  • Baseline PRO data was obtained from 153 patients (93.3 %), and 74 (48.4 %) returned follow-up questionnaires. (biomedcentral.com)
  • There are additional challenges to designing high-quality RCTs in emergency surgery as admission to the hospital is unplanned, and patients are acutely unwell making acquisition of informed consent for research and baseline data collection difficult. (biomedcentral.com)
  • Additionally, there may be insufficient time for patients to complete baseline questionnaires before urgent surgical intervention. (biomedcentral.com)
  • The primary endpoint was the proportion of patients who had a reduction of ≥30.0% in average weekly worst abdominal pain and an increase of ≥1 weekly complete spontaneous bowel movement from baseline, both in the same week, for ≥6 of the first 12 treatment weeks (6/12-week combined responder). (lww.com)
  • The authors conducted a systematic review and baseline meta-analysis of studies on the impact of SARS-Cov-2 infection on morbidity and mortality among cancer patients not previously vaccinated against the virus. (elifesciences.org)
  • OBJECTIVE To compare four different inception cohorts of patients with early rheumatoid arthritis (RA) with respect to treatment strategies, disease activity, and outcome during a five year follow up period. (bmj.com)
  • Objective To assess the impact of certolizumab pegol (CZP) on patient-reported outcomes (PROs) in rheumatoid arthritis (RA), and to interpret these results using number needed to treat (NNT), and associations between PRO responses and longer term outcomes. (bmj.com)
  • Impact of adverse events on outcomes in intensive care unit patients. (ahrq.gov)
  • The only significant predictors of outcome were haemoglobin level and number of spaces involved. (edu.ng)
  • Large lesion size (≥109 mm(2)) and the existence of subchondral cysts were significant predictors of unsatisfactory clinical outcomes in group A (P = .04 and .03, respectively). (researchgate.net)
  • reported in a prospective study of 58 SAH patients that a negative energy balance during the first 7 days after SAH correlated with the number of infectious complications 10 . (nature.com)
  • These researchers also showed in a prospective observational study of 229 SAH patients that a negative nitrogen balance during the first 14 post-bleed days is a risk factor for infectious complications and is associated with poor outcomes (mRS ≥ 4) at 3 months 11 . (nature.com)
  • Subjects with clinical diagnosis of abscess or cellulitis were more likely to have a successful outcome without complications. (edu.ng)
  • However, none of the patients experienced intraoperative complications or neurovascular exposure. (bvsalud.org)
  • However, preoperative CBCT had no effect on other QoL parameters and intraoperative complications in medium- risk patients . (bvsalud.org)
  • Mood difficulties are common among patients with diabetes and are linked to poor blood glucose control and increased complications. (diabetesjournals.org)
  • Our present study aims to investigate the effect of adrenalectomy on BP management within trHTN patients, and to explore clinical predictors for postoperative BP normalization. (degruyter.com)
  • Objective To assess the association between off-hour (weekends and nights) presentation, door to balloon times, and mortality in patients with acute myocardial infarction. (bmj.com)
  • Objective To investigate the accuracy of the National Early Warning Score (NEWS) to predict mortality and adverse clinical outcomes for patients with community-acquired pneumonia (CAP) compared to standard risk scores such as the pneumonia severity index (PSI) and CURB-65. (bmj.com)
  • Our objective was to study the ability of the lung clearance index (LCI), a measure of ventilation inhomogeneity, to detect a treatment response to hypertonic saline inhalation in paediatric patients with CF with normal spirometry. (bmj.com)
  • Objective: We performed an integrated cross-sectional analysis of relationships between long-term care work environments, employee and resident satisfaction, and quality of patient care. (cdc.gov)
  • To assess patients' self-estimates of the burden of disease in vasculitis and to compare data across patient populations from the US, Germany, and the UK. (nih.gov)
  • Outcome assessment in vasculitis primarily focuses on physician evaluations of disease activity and damage. (nih.gov)
  • Little is known about the patients' perspectives regarding the burden of disease. (nih.gov)
  • Patients were also asked to list the 5 most troublesome aspects of the disease. (nih.gov)
  • On the 25 patients included, the mean age was 33.3 years (SD = 9.7) with a mean duration of disease of 7.48 years (SD = 7.1). (frontiersin.org)
  • CONCLUSION This observational study of cohorts of patients with early RA confirms that early aggressive treatment results not only in a more rapid reduction of disease activity but also in less radiographic progression in the long term. (bmj.com)
  • PROs assessed included pain, patient's global assessment of disease activity (PtGA), physical function, fatigue and health-related quality of life. (bmj.com)
  • More patients with improvements ≥MCID in pain at week 6 than those at week 12 had lower disease activity at week 24. (bmj.com)
  • Patients do not have to have severe disease or be at high risk of severe illness to enroll in the study, and remote enrollment is available. (cdc.gov)
  • The trial includes a placebo-controlled, randomized arm and an open-label option for patients with severe disease, who have severe immunodeficiency, are pregnant or breastfeeding, who are under 18 years of age, or are taking medications that could affect tecovirimat levels. (cdc.gov)
  • Disease activity encompasses remission (complete absence of disease activity), response (quantifiable improvement in disease activity), and relapse (increase in disease activity from a previous low or absent state), which are used as outcomes in clinical trials 1 , 2 , 3 , 4 , 5 . (jrheum.org)
  • Conclusions The LCI, but not spirometry was able to detect a treatment effect from HS inhalation in patients with CF with mild disease and may be a suitable tool to assess early intervention strategies in this patient population. (bmj.com)
  • There is increasing evidence that cystic fibrosis (CF) lung disease which is responsible for a shortened life span in most patients begins shortly after birth and progresses even in the absence of clinical signs and symptoms. (bmj.com)
  • However, its use in young patients with mild CF lung disease is limited by its insensitivity to peripheral airways disease and the need for active cooperation to perform the manoeuvre. (bmj.com)
  • Cross-sectional studies done to date in patients with CF suggest that the LCI is more sensitive at detecting lung disease than spirometry. (bmj.com)
  • 9-15 The LCI is a potentially useful end point for clinical trials in patients with CF with mild lung disease, but data from interventional and longitudinal studies with the currently used equipment are lacking. (bmj.com)
  • Newly diagnosed cancer patients are frequently found suffering from a metastatic disease, which poses additional challenges to the delivery of effective therapies. (cambridge.org)
  • As the major risk in EPP patients is liver disease, a regular follow-up of hepatic involvement is essential. (orpha.net)
  • We evaluated the construct validity of 4-, 7-, and 8-item PROMIS-Fatigue SFs in RA patients across the range of disease activity. (springer.com)
  • Cancer patients are also a high-risk group due to their compromised immune systems and vulnerability to infection resulting from their disease and the treatments ( Kamboj and Sepkowitz, 2009 ). (elifesciences.org)
  • Interpretation: Despite similar disease severity and ventilation management, ICU mortality in patients without ARDS is higher in MICs than in HICs, with a strong association with country-level economic status. (lu.se)
  • Prognosis and Determinants of Asthma Morbidity in World Trade Center Rescue and Recovery Workers' will provide a detailed assessment of the clinical presentation, relationship with exposure, treatment needs, evaluation of the influence of comorbidities on disease presentation, and the impact of asthma on the quality of life of WTC workers. (cdc.gov)
  • The WHO Regional Office for Africa conducted a rapid assessment of the continuity of essential oral health services in the context of COVID-19 to understand the situation and identify important actions to strengthen oral health promotion and oral disease prevention and control as part of the overall health system. (who.int)
  • A recent study analyzed concurrent immunotherapy and stereotactic radiotherapy in melanoma patients with brain metastases. (medpagetoday.com)
  • We reviewed the patient charts to measure severity of illness and to determine whether the patient was referred to the emergency department by a community physician. (cmaj.ca)
  • After adjusting for important confounders, including patient sex, previous hospital admissions, diagnosis and severity of illness, we found that stays in the emergency department were 1.2 hours longer on average for patients with an information gap than for those without one. (cmaj.ca)
  • We selected three outcomes: mortality, access to ICU, and COVID-19 severity or hospitalization. (elifesciences.org)
  • Our meta-analysis indicates a twofold increased risk of adverse outcomes (mortality, ICU admission, and severity of COVID-19) in unvaccinated COVID-19 patients with cancer compared to COVID-19 patients without cancer. (elifesciences.org)
  • 4 at admission independently predicted patients' functional outcome status at 3 months after aSAH 7 . (nature.com)
  • Settings Patients with CAP included on admission to the emergency departments (ED) of 6 tertiary care hospitals in Switzerland. (bmj.com)
  • The most common reason for admission to the hospital was abdominal pain ( n = 120, 72.3 % recruited patients), of whom 50 (30.1 %) required operative intervention. (biomedcentral.com)
  • Despite the increasing availability of antimicrobial therapy and healthcare services, odontogenic orofacial infections remain a cause of admission and mortality of patients. (edu.ng)
  • PROMIS has worked to unify the field of patient-reported outcome (PRO) measurement through the promotion of a common, systematic measurement system broadly applicable across clinical research. (wikipedia.org)
  • PROMIS incorporates and translates cutting-edge science into practical, easy to use tools for clinicians: For example, PROMIS implements Computer Adaptive Test (CAT) software which tailors the PRO assessment to the individual patient by selecting the most informative set of questions based on responses to previous questions. (wikipedia.org)
  • There is no standardized measure for its assessment nor data concerning the performance of PROMIS-Fatigue short forms (SFs) in people with RA. (springer.com)
  • However, there is limited data regarding the natural history, self-management, and impact of comorbidities on asthma outcomes. (cdc.gov)
  • This technique has been found to be suitable for health problems which warrant a multidimensional and individualised approach to treatment planning and outcome measurement. (kcl.ac.uk)
  • there is at least one validated outcome measurement instrument available for each domain. (jrheum.org)
  • Dr Kamudoni trained as a Pharmacoeconomist and a Clinical Outcome Measurement Scientist at Cardiff University. (nshealth.ca)
  • He maintains an active research interest in methodological issues in the integration of electronic health records with prospective PRO assessments, and the application of item response theory in PRO measurement among others. (nshealth.ca)
  • In a 12-month follow-up randomized clinical trial, we aimed to measure the efficacy of a brief family psychoeducation program in terms of reducing relapse risk and improving medication adherence in patients, as well as reducing caregiver burden, depression and increasing knowledge of the illness. (frontiersin.org)
  • 1-11 However, an important drawback in applying DMARDs is the high incidence of patients discontinuing treatment because of a lack of efficacy or the occurrence of adverse reactions. (bmj.com)
  • To understand symptom relief more broadly, the assessment of clinically meaningful improvements using minimal clinically important differences (MCIDs) 1 allows an understanding of the efficacy of a new therapy in a more meaningful way. (bmj.com)
  • Efficacy of Tenapanor in Treating Patients With Irritable Bo. (lww.com)
  • This phase 3 trial assessed the long-term efficacy and safety of tenapanor 50 mg b.i.d. for the treatment of patients with irritable bowel syndrome with constipation (IBS-C). (lww.com)
  • 16 17 Due to its mechanism of action, HS is an attractive early intervention strategy, but has never been studied in patients with CF with normal lung function due to the difficulty in assessing its efficacy. (bmj.com)
  • Fellowship grant for project: "Assessment of dialysis efficacy in pediatric patients. (msdmanuals.com)
  • For patients, family psychoeducation has been effective in improving outcomes in schizophrenia with a better level of global functioning, medication adherence, and a reduction in the use of healthcare resources and the frequency of relapse ( 6 - 8 ). (frontiersin.org)
  • How do comorbid mental health conditions (depression and PTSD) and asthma self-management behaviors (medication adherence, self-monitoring, use of action plans, and allergy avoidance) affect outcomes (asthma control, resource utilization, and quality of life) in WTC workers with asthma? (cdc.gov)
  • Self-reported adherence assessments based on a validated scale showed than only 24% were adherent to their controller medication. (cdc.gov)
  • Relate assessment findings to underlying pathological and physiological changes in the patient's condition. (cnm.edu)
  • During the observation of the surgeon, the student is exposed to the discussion between the surgeon and the medical staff - resident, nurse practitioner, etc. - during review of each patient's condition and to the interaction between surgeon and patient during the physical examination. (hopkinsmedicine.org)
  • Value assessments are an important tool in moving toward better, more affordable health care. (phrma.org)
  • Unfortunately, conventional value assessments, also known as health technology assessments (HTAs), typically only account for health care costs, and controversial metrics like the quality-adjusted-life-year (QALY). (phrma.org)
  • The rehabilitation intervention is geared toward the unique problems and needs of each patient and is implemented by a multidisciplinary team of health care professionals. (medscape.com)
  • Providers, in conjunction with state health departments, can also request a clinical consultation regarding management of hospitalized patients with mpox by calling the CDC EOC or [email protected] . (cdc.gov)
  • No one of these instrument types can get to the bottom of the full scope of patient perception, but they're a great start when it comes to ascertaining the generic health status of a patient at multiple care points. (hubofarticles.com)
  • According to PROM protocols, patients place their health on a rating system based on how easy or how difficult it is to complete tasks that one could otherwise perform unhindered. (hubofarticles.com)
  • Because there are a plethora of measurements regarding health, a number of ways to input vital patient information creates the need and demand for a variety of instruments. (hubofarticles.com)
  • Opeeka's P-CIS supports all kinds of health outcomes in regards to software and documentation choices. (hubofarticles.com)
  • Care may be fragmented if patients attend multiple sectors of the health system. (cmaj.ca)
  • Perform a comprehensive history and physical examination to identify factors affecting the health and health needs of a patient. (cnm.edu)
  • There has been a cultural shift toward patient engagement in health, with a growing demand from patients to access their results. (jmir.org)
  • The Lymphoma Intervention (LIVE) trial is conducted to examine the impact of return of individual patient-reported outcome (PRO) results and a web-based self-management intervention on psychological distress, self-management, satisfaction with information, and health care use in a population-based setting. (jmir.org)
  • We aspire to become the recognized authority on issues of patient outcomes and safety and on health care system performance in spine. (hopkinsmedicine.org)
  • OHE lunchtime seminar with Leeza Osipenko (NICE Scientific Advice), Nancy Delvin and François Maignen (OHE) Health Technology Assessment (HTA) scientific advice (SA) was created by the National Institute for Health and Care Excellence in 2009. (ohe.org)
  • Health Technology Assessment (HTA) scientific advice (SA) was created by the National Institute for Health and Care Excellence in 2009. (ohe.org)
  • Nursing perception of the impact of medication carts on patient safety and ergonomics in a teaching health care center. (ahrq.gov)
  • NHDIIBS and ATSDR completed and distributed the Public Comment Release of the Public Health Assessment for Pease Air Force Base on July 28, 1999. (cdc.gov)
  • Following this, NHDHHS and ATSDR held a public meeting on August 11, 1999, to present the findings of the draft public health assessment. (cdc.gov)
  • Therefore, the exposures evaluated in the public health assessment may have underestimated both the duration and levels of the actual exposures to TCE in the base water supply. (cdc.gov)
  • A recent publication identified examples of performance objectives and outcome metrics to be used within public health practice for successful implementation of genomic activities. (cdc.gov)
  • The group is composed of key stakeholders from federal and state programs, researchers, patient advocates, and clinical practitioners with expertise in public/population health, health disparities, health literacy, implementation science, medical genetics, and patient advocacy. (cdc.gov)
  • BRAF inhibitor therapy was administered concurrently with SRS in 34.4% of the patients with BRAF mutations and 63.8% of all the patients had IT concurrently with SRS, which was defined as starting IT within 4 weeks of SRS. (medpagetoday.com)
  • Patients with STEMI presenting during off-hours were less likely to receive percutaneous coronary intervention within 90 minutes (odds ratio 0.40, 0.35 to 0.45) and had longer door to balloon time by 14.8 (95% confidence interval 10.7 to 19.0) minutes. (bmj.com)
  • For patients, the family psychoeducation intervention significantly reduced the risk of relapse with a significant effect found at 12 months follow-up ( p = 0.014). (frontiersin.org)
  • Therefore, family intervention should be developed to reduce the burden of caregivers and enhance patients' prognosis. (frontiersin.org)
  • These goals are achieved through patient and family education, exercise training, psychosocial and behavioral intervention, and outcome assessment. (medscape.com)
  • Developed originally in the context of upper limb intervention, the approach as now been adapted to encompass outcome evaluation in both upper and lower limb spasticity. (kcl.ac.uk)
  • 7 Forced expiratory volume in 1 s (FEV 1 ) has traditionally been the main outcome measure in therapeutic intervention studies. (bmj.com)
  • 7%), a therapeutic intervention for patients with CF, is believed to target a direct consequence of cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction, airway surface dehydration, and has previously been shown to increase mucociliary clearance, improve FEV 1 and decrease the number of pulmonary exacerbations. (bmj.com)
  • Patients with lymphoma who completed the web-based questionnaire were equally randomized to care as usual, return of PRO results, and return of PRO results plus self-management intervention. (jmir.org)
  • The Functional Independence Measure (FIM) is a global measure of disability and can be scored alone or with additional items that formulate the Functional Assessment Measure (FAM). (kcl.ac.uk)
  • This module will discuss the advantages and disadvantages of conventional fixed treatment options for replacing missing teeth and compare their published treatment outcomes and indications with those of implant-supported prostheses. (iti.org)
  • Results 48 studies with fair quality, enrolling 1 896 859 patients, were included in the meta-analysis. (bmj.com)
  • Results The 47 included studies encompassed 62 cohorts, representing 2312 patients. (bmj.com)
  • Information gaps most commonly comprised medical history (58%) and laboratory test results (23.3%) and were felt to be essential to patient care in 47.8% of the cases. (cmaj.ca)
  • Return of PRO results included comparison with age- and sex-matched peers and was built into the Patient-Reported Outcomes Following Initial Treatment and Long-Term Evaluation of Survivorship registry. (jmir.org)
  • Of all invited patients, 51.1% (456/892) responded and web-based participants (n=227) were randomly assigned to care as usual (n=76), return of PRO results (n=74), or return of PRO results and access to Living with lymphoma (n=77). (jmir.org)
  • Return of individual PRO results seems to meet patients' wishes but had no beneficial effects on patient outcome. (jmir.org)
  • Direct observation may be time consuming and a thorough evaluation of all skills may not be possible in the context of out-patient or home-based care. (nih.gov)
  • As confirmed by previous studies, the brief multifamily program (consisting of six sessions over a period of 1.5 months) was found to be effective in improving outcomes for caregivers (e.g., burden, depression, knowledge) and patients (e.g., preventing relapse) in the context of routine care. (frontiersin.org)
  • We have been developing outcome and assessment tools for research, clinical care and audit for over two decades. (kcl.ac.uk)
  • Yes, physicians have their breadth of notes which can do a great job defining every step of patient care, but there's nothing quite like the real-time of the patient themselves. (hubofarticles.com)
  • Several existing APHA policy statements address the need for improved access to dental care, eye care, and/or medical care in certain patient populations, but this is the only statement that specifically addresses diabetes. (apha.org)
  • Identifying preventable factors of reduced response to therapy would translate into better care of cancer patients. (cambridge.org)
  • The rise of consumerism has given patients more ownership of their care than ever before. (mgma.com)
  • Phreesia recently surveyed over 4,000 patients about their digital expectations for their care. (mgma.com)
  • We are dedicated to improving patient safety and outcomes through furthering knowledge and increasing the efficiency of spine care. (hopkinsmedicine.org)
  • Intensive care unit (ICU) patients are vulnerable from a patient safety standpoint, with hospital-acquired infections and medication errors being particularly common examples of adverse events (AEs). (ahrq.gov)
  • Background: Geoeconomic variations in epidemiology, the practice of ventilation, and outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. (lu.se)
  • We anticipate continued widespread use of this guide in assisting practitioners in the care of their patients with diabetes. (cdc.gov)
  • This publication is designed to help the primary care practitioner in the day-to-day management of patients with diabetes. (cdc.gov)
  • K-means cluster analysis was applied to investigate clustered associations between safe resident handling program (SRHP) performance, resident care outcomes, employee satisfaction, rates of workers' compensation claims, and resident satisfaction. (cdc.gov)
  • Conclusion: The observed clustered relationships support the utility of integrated performance assessment in long-term care facilities. (cdc.gov)
  • The anticipated patient outcomes of a comprehensive pulmonary rehabilitation program include increased independence and improved QOL, as well as fewer hospitalizations or shorter hospitalization time. (medscape.com)
  • In this study, we examined the association of clinical outcome with the Controlling Nutritional Status (CONUT) score during hospitalization in aSAH patients. (nature.com)
  • These findings indicate that CONUT score during hospitalization may be a useful daily marker for predicting poor outcomes in aSAH patients. (nature.com)
  • Thus, it is important to identify a useful marker of the nutritional status of SAH patients during hospitalization. (nature.com)
  • Here, we retrospectively analyzed the relationship between clinical outcomes and the CONUT score in aSAH patients during hospitalization. (nature.com)
  • Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o. (medscimonit.com)
  • A sizable number of trHTN patients may have adrenal lesions. (degruyter.com)
  • Background: The ideal treatment for osteochondral lesions of the talus (OLTs) is still controversial, especially in older patients. (researchgate.net)
  • CDC recommends that three lesions per patient be swabbed. (cdc.gov)
  • The Spine Outcomes Research Center is a multidisciplinary group committed to improving patient outcomes and applying high-quality and purposeful research to professional practice. (hopkinsmedicine.org)
  • The Depression Intensity Scale Circles (DISCs) have been developed and adapted for use in the assessment of people with brain injuries and symptoms of depression. (kcl.ac.uk)
  • No patients in 2 of the 5 study cohorts were on antiretroviral therapy. (cdc.gov)
  • METHOD Data from cohorts of patients with early RA, with a standardised assessment at least every six months for five years from four different centres, were included in one database. (bmj.com)
  • The proportion of patients receiving NAC followed by surgery was significantly higher in the eligible group than in the ineligible group ( P = 1.07 × 10 -11 ), whereas the proportion of patients receiving CRT was higher in the ineligible group than in the eligible group ( P = 3.09 × 10 -3 ). (biomedcentral.com)
  • A companion publication entitled Take Charge of Your Diabetes: A Guide for Patients is available. (cdc.gov)
  • Direct psychological consequences can arise from any one of these factors, making it harder for patients to treat their diabetes and live productive, enjoyable lives. (cdc.gov)
  • Data from 264 patients with vasculitis from 3 countries were collected. (nih.gov)
  • Data extraction Studies' characteristics and outcomes data were extracted. (bmj.com)
  • Standardised mean differences (Cohen's d) between cognitive, motor and language outcome of patients with congenital gastrointestinal malformations and normative data (39 studies) or the studies' control group (8 studies) were aggregated across studies using random-effects meta-analysis. (bmj.com)
  • Is a Data Protection Impact Assessment required? (ebmt.org)
  • Furthermore, surgical trials often focus on outcomes relevant to surgeons (e.g. technical endpoints such as morbidity), and there is a lack of RCTs in surgery with high-quality patient-reported outcome (PRO) data [ 5 , 6 ]. (biomedcentral.com)
  • The data were obtained by questionnaire-interview with the patient themselves, if they were mature and well enough to answer the questions. (who.int)
  • In the case of younger children or patients who were not well enough as a result of severe injury, the data were obtained from relatives who attended the unit. (who.int)
  • Given the increasing importance of incorporating both radiological and clinical parameters in response assessment, [these] data [are] important for trial planning and design. (medpagetoday.com)
  • In this analysis we aim to address these gaps using individual patient data of four large observational studies. (lu.se)
  • data available in 3174 [82%] of 3852 patients). (lu.se)
  • This study aimed to evaluate the treatment strategies and prognosis of older patients with locally advanced ESCC in a real-world setting. (biomedcentral.com)
  • This study aimed to evaluate whether utilizing additional cone beam computed tomography (CBCT) imaging has any effect on quality of life and healing outcome following periapical surgery compared with periapical radiographs (PR). (bvsalud.org)
  • We retrospectively evaluated 381 older patients (≥ 65 years) with locally advanced ESCC (stage IB/II/III, excluding T4) who received anticancer therapy at 22 medical centers in Japan. (biomedcentral.com)
  • Patients with melanoma BM who were treated with SRS between October 2015 and June 2019 were identified retrospectively from the medical records of one institution. (medpagetoday.com)
  • This is the first large-scale study with a long-term follow-up investigating the association of the National Early Warning Score (NEWS) and adverse outcome in patients with community-acquired pneumonia. (bmj.com)
  • In certain clinical situations, extending the duration of tecovirimat treatment beyond the standard 14-day course at the standard dose and dosing interval is permissible per treating provider's clinical judgment on an individual patient case-by-case basis of risk-benefit with submitting the required Clinical Outcome form to CDC. (cdc.gov)
  • Times to onset of improvements greater than or equal to minimum clinically important differences (MCIDs) in pain as a determinant of clinical outcomes at week 24 were compared between week 6 and 12 responders, and in patients with improvements in pain ≥MCID at week 12 (week 12 responders/non-responders). (bmj.com)
  • Patient-centric outcome assessment of endodontic microsurgery using periapical radiography versus cone beam computed tomography: A randomized clinical trial. (bvsalud.org)
  • Participants A total of 925 patients with confirmed CAP were included. (bmj.com)
  • when using logistic regression analysis, the outcome of the burn injury was significantly associated with age, sex, total surface area burnt and degree and depth of the burn. (who.int)
  • It is undeniable that medical anti-cancer options significantly improved over the past 10-15 years, yet it is also self-evident that they did not translate into improved outcome for advanced cancer patients in the real world, at least as far as survival rate is considered. (cambridge.org)
  • Anticipate and prospectively intervene to improve patient outcome. (cnm.edu)
  • Presenting visual acuity (PVA) was measured using the Rapid Assessment of Avoidable Blindness (RAAB) methodology. (bmj.com)
  • Characteristics of morbidity and mortality conferences associated with the implementation of patient safety improvement initiatives, an observational study. (ahrq.gov)
  • Conclusion This systematic review suggests that patients with acute myocardial infarction presenting during off-hours have higher mortality, and patients with STEMI have longer door to balloon times. (bmj.com)
  • To carry out a systematic review of the studies comparing the outcome of unvaccinated COVID-19 patients with and without cancer, a search string was devised which was used to identify relevant publications in PubMed up to December 31, 2020. (elifesciences.org)
  • Schizophrenia is recognized for its severe impact on both patients and caregivers. (frontiersin.org)
  • Since the emergence of SARS-CoV-2, many studies have been conducted on the outcomes of COVID-19, in order to identify factors associated with a higher death rate and a more severe infection course. (elifesciences.org)