• lines
  • Crown antibodies pass additional stringent quality requirements, including extended control sets, uniform results against multiple biologically relevant cell lines and tissues, and function in multiple applications. (abgent.com)
  • Combinations of gemcitabine and trabectedin exert modest synergistic cytotoxic effects on two pancreatic cancer cell lines. (frontiersin.org)
  • Extensive experimental data were obtained for two pancreatic cancer cell lines (MiaPaCa-2 and BxPC-3), including cell proliferation rates over 0-120 h of drug exposure, and the fraction of cells in different cell cycle phases or apoptosis. (frontiersin.org)
  • PharmaMar S.A.U., Madrid, Spain) is a promising anticancer agent that has demonstrated clinical activity in many drug-resistant cancer cell lines, and has been approved by the US Food and Drug Administration for advanced soft tissue sarcoma. (frontiersin.org)
  • cancer
  • Here, systems pharmacodynamic (PD) models that integrate cellular response data and extend a prototype model framework were developed to characterize dynamic changes in cell cycle phases of cancer cell subpopulations in response to gemcitabine and trabectedin as single agents and in combination. (frontiersin.org)