• Acne vulgaris is characterized by noninflammatory, open or closed comedones and by inflammatory papules, pustules, and nodules. (medscape.com)
  • This incites a foreign body inflammatory response that is clinically characterized by painful or pruritic papules, pustules, and nodules. (contemporarypediatrics.com)
  • Acne vulgaris is the formation of comedones, papules, pustules, nodules, and/or cysts as a result of obstruction and inflammation of pilosebaceous units (hair follicles and their accompanying sebaceous gland). (msdmanuals.com)
  • Papules and pustules occur when C. acnes colonizes the closed comedones, breaking down sebum into free fatty acids that irritate the follicular epithelium and eliciting an inflammatory response by neutrophils and then lymphocytes, which further disrupts the epithelium. (msdmanuals.com)
  • The chronic inflammatory condition that usually includes comedones, inflamed papules, and pustules (pimples) is called acne. (wikipedia.org)
  • An inflammatory phase often follows, in which sterile papules and pustules (leading to the designation of rosacea as adult acne) develop. (merckmanuals.com)
  • Granuloma annulare (GA) is a cutaneous inflammatory disorder of unknown cause, typically characterized by an annular arrangement of dermal papules and nodules. (bvsalud.org)
  • C36281 Integumentary System Finding C118464 Adverse Events Terminology C27195 Acne Acne Acne Vulgaris An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin. (nih.gov)
  • An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin. (nih.gov)
  • Closed comedones are the precursor lesions to inflammatory acne. (msdmanuals.com)
  • Whether a skin condition classifies as acne depends on the number of comedones and infection. (wikipedia.org)
  • Oil production in the sebaceous glands increases during puberty, causing comedones and acne to be common in adolescents. (wikipedia.org)
  • What effect shaving has on the development of comedones or acne is unclear. (wikipedia.org)
  • Some skin products might increase comedones by blocking pores, and greasy hair products (such as pomades) can worsen acne. (wikipedia.org)
  • People of Latino and recent African descent may experience more inflammation in comedones, more comedonal acne, and earlier onset of inflammation. (wikipedia.org)
  • Solar comedones (sometimes called senile comedones) are related to many years of exposure to the sun, usually on the cheeks, not to acne-related pathophysiology. (wikipedia.org)
  • Some acne treatments target infection specifically, but some treatments are aimed at the formation of comedones, as well. (wikipedia.org)
  • Laser treatment for acne might reduce comedones, but dermabrasion and laser therapy have also been known to cause scarring. (wikipedia.org)
  • The age of onset and absence of comedones help distinguish rosacea from acne. (merckmanuals.com)
  • Acne can present as noninflammatory lesions, inflammatory lesions, or a mixture of both, affecting mostly the face but also the back and chest. (medscape.com)
  • Hidradenitis suppurativa (HS), also called acne inversus, is a chronic inflammatory skin condition with lesions including deep-seated nodules and abscesses, draining tracts, and fibrotic scars. (nih.gov)
  • Nodular malignant melanoma (20%) presents as a raised brown-black nodule, although occasionally amelanotic lesions are seen. (brainkart.com)
  • Acne develops from the following four factors: (1) follicular epidermal hyperproliferation with subsequent plugging of the follicle, (2) excess sebum production, (3) the presence and activity of the commensal bacteria Cutibacterium acnes (formerly Propionibacterium acnes ), and (4) inflammation. (medscape.com)
  • Cutibacterium acnes is the suspected infectious agent in acne. (wikipedia.org)
  • Scattered pustules appear on the face of this person with acne. (msdmanuals.com)
  • It can proliferate in sebum and cause inflamed pustules (pimples) characteristic of acne. (wikipedia.org)
  • Treatment of acne vulgaris should be directed toward the known pathogenic factors, including follicular hyperproliferation, excess sebum, C acnes (formerly P acnes ), and inflammation. (medscape.com)
  • Nodules and cysts are other manifestations of inflammatory acne. (msdmanuals.com)
  • In rare but severe cases, acne vulgaris could lead to acne conglobata, with highly inflammatory nodulocystic acne and interconnected abscesses. (medscape.com)
  • Polycystic ovarian syndrome (PCOS): Consider PCOS in female patients with oligomenorrhea, hirsutism and/or acanthosis nigricans in addition to acne. (medscape.com)
  • The persistent itchy and painful keloidal nodules flattened with high-potency topical steroids and intralesional steroids treated the larger and more resistant nodules. (contemporarypediatrics.com)
  • Nodules and cysts can be painful. (msdmanuals.com)
  • Nodules are inflamed, painful, deep bumps under the skin. (wikipedia.org)
  • Acne vulgaris is a common chronic skin disease involving blockage and/or inflammation of pilosebaceous units (hair follicles and their accompanying sebaceous gland). (medscape.com)
  • Acne vulgaris typically affects the areas of skin with the densest population of sebaceous follicles (eg, face, upper chest, back). (medscape.com)
  • Perioral Dermatitis Perioral dermatitis is an erythematous, papulopustular facial eruption that resembles acne and/or rosacea but typically starts around the mouth. (merckmanuals.com)
  • A comedo can be open (blackhead) or closed by skin (whitehead) and occur with or without acne. (wikipedia.org)
  • Acne is the most common skin disease in the US and affects 80% of the population at some point in life. (msdmanuals.com)
  • The most appropriate treatment is based on the grade and severity of the acne. (medscape.com)
  • Make-up and skin products that are oil-free and water-based may be less likely to cause acne. (wikipedia.org)
  • The malignant change is heralded by the appearance of a nodule in lentigo maligna. (brainkart.com)
  • Complementary medicine options for acne in general have not been shown to be effective in trials. (wikipedia.org)
  • Acne develops on the face and upper trunk. (msdmanuals.com)
  • Associations between acne exacerbations and inadequate face washing, masturbation, and sex are unfounded. (msdmanuals.com)
  • Acne may abate in summer months because of sunlight's anti-inflammatory effects. (msdmanuals.com)