AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureHumanitiesInformation ScienceNamed GroupsHealth CareGeographicals
Molecular EpidemiologyEpidemiologyElectrophoresis, Gel, Pulsed-FieldPhylogenyGenotypeDisease OutbreaksDNA FingerprintingBacterial Typing TechniquesCluster AnalysisMolecular TypingSequence Analysis, DNAPathologyDNA, BacterialMultilocus Sequence TypingPolymorphism, Restriction Fragment LengthIncidencePrevalenceCameroonSerotypingPolymerase Chain ReactionCross InfectionGenetic VariationMinisatellite RepeatsMicrobial Sensitivity TestsRisk FactorsMolecular Sequence DataSEER ProgramUnited StatesAnti-Bacterial Agentsbeta-LactamasesInfant, NewbornRibotypingCaliciviridae InfectionsGastroenteritisEpidemiologic MethodsSeasonsSequence HomologyDrug Resistance, BacterialPopulation SurveillanceFecesStaphylococcal InfectionsPathology, ClinicalDrug Resistance, Multiple, BacterialChinaRandom Amplified Polymorphic DNA TechniqueKlebsiella InfectionsItalyAge DistributionMycobacterium tuberculosisPathology, SurgicalSpainKlebsiella pneumoniaeHospitalsTuberculosisTaiwanFranceBias (Epidemiology)Escherichia coli InfectionsBrazilCarrier StateEnvironmental MicrobiologyRNA, ViralNorovirusAge FactorsAnimals, WildPhylogeographyDisease ReservoirsAcinetobacter InfectionsRetrospective StudiesArgentinaCattle DiseasesEuropeAdenovirus Infections, HumanRotavirus InfectionsDNA, ProtozoanAstroviridae InfectionsConfounding Factors (Epidemiology)Base SequenceIndiaEpidemicsDisease Transmission, InfectiousStreptococcus pneumoniaeHemodialysis Units, HospitalBacteremiaIsraelEvolution, MolecularZoonosesCommunity-Acquired InfectionsMycological Typing TechniquesSapovirusEpidemiologic Research DesignWorld HealthAfricaDiarrheaDysentery, BacillaryBird DiseasesColombiaCommunicable Diseases, Emergingbeta-Lactam ResistanceEnterobacteriaceae Infections
International Molecular Pathological EpidemiologyEtiologyPathogenesisGeneticsImmunologyDiagnosisSubtypesMechanismsBiologyImmunologicalEpidemiologicalBrigham and WomeDepartment of EpidemiologyHistopathologyPrognosisGenomicsBiomarkersBiostatisticsDiagnosticsAlterationsGeneral PathologyIntestinal pathologyPhenotypesMutations2022CellularPrognosticInterdisciplinaryOgino2017AssessmentPreventionAnalysesDiseasesMethodologiesRisk factorsTumorsPathwaysResearchCancerAbstractImmunohistochemistryAnatomyEncompassesTissueFrequentTumorFacultyClassification
International Molecular Pathological Epidemiology5
  • The International Molecular Pathological Epidemiology (MPE) Meeting Series, which was established in 2013, has been open to the research community around the world, and five meetings were held through 2021. (wikipedia.org)
  • The 3rd International Molecular Pathological Epidemiology (MPE) Meeting concluded as a great success! (harvard.edu)
  • The International Molecular Pathological Epidemiology (MPE) Meeting Series is open to the international research community with free registration. (mpemeeting.org)
  • The International Molecular Pathological Epidemiology (MPE) Meeting Series" (precisely word-by-word) is the formal meeting series name. (mpemeeting.org)
  • The 6th International Molecular Pathological Epidemiology (MPE) Meeting: 10-Year Anniversary Summit" (formal meeting name) will be held in 2023. (mpemeeting.org)
Etiology2
  • Pathology and epidemiology share the same goal of elucidating etiology of disease, and MPE aims to achieve this goal at molecular, individual and population levels. (wikipedia.org)
  • General Pathology is a multidisciplinary science of medicine that studies the etiology and pathogenesis of diseases and in particular the reactivity of the organism and in cases where such reactivity is not adequate or insufficient, the mechanisms that determine the persistence of the pathological condition. (uninsubria.eu)
Pathogenesis6
  • This GWAS-MPE approach can give not only more precise effect estimates, even larger effects, for specific molecular subtypes of the disease, but also insights into pathogenesis by linking genetic variants to molecular pathologic signatures of disease. (wikipedia.org)
  • Causal inference Epidemiological method Epidemiology Evidence-based medicine Molecular diagnostics Molecular epidemiology Molecular medicine Molecular pathology Pathogenesis Pathology Personalized medicine Precision medicine Public health Systems biology Ogino S, Lochhead P, Giovannucci E, Meyerhardt JA, Fuchs CS, Chan AT (June 2014). (wikipedia.org)
  • In the past few decades, our knowledge of disease pathogenesis has improved considerably, and disease classification has also transformed, incorporating molecular mechanisms of disease. (mpemeeting.org)
  • The book consists of 5 themed sections on: epidemiology, pathogenesis, screening and early detection, molecular genetics, and clinical aspects and management. (stanford.edu)
  • Herein they describe the recent emergence of molecular pathological epidemiology (MPE), which represents an integration of population and molecular biologic science to gain insights into the etiologies, pathogenesis, evolution, and outcomes of complex multifactorial diseases. (elsevierpure.com)
  • 2 The pathogenesis of lung cancer involves the accumulation of several molecular abnormalities over time. (bmj.com)
Genetics5
  • Knowledge of immunology and genetics are also important to understand Anatomic Pathology. (unibo.it)
  • It also provides information on clinical features, pathology, genetics, prognosis, and protective factors for each of the tumour types covered. (iarc.fr)
  • This book provides essential information on recent advances in molecular genetics, epidemiology, translational research, and the latest results of clinical trials on mesothelioma. (stanford.edu)
  • Research at IAB encompasses a wide range of topics and expertise, from molecular genetics and epigenetics to cell biology, molecular pathology, parasitology, immunology and environmental epidemiology. (iab-grenoble.fr)
  • To take the General Pathology exam you must have passed the Biology and Genetics and Physiology exams. (uninsubria.eu)
Immunology1
  • Advancing integrative molecular and population-level health science and addressing the unique research challenges specific to the field of MPE requires bringing together experts in diverse fields, including pathology, epidemiology, biostatistics, computational biology, bioinformatics, genomics, immunology, and nutritional and environmental sciences. (mpemeeting.org)
Diagnosis3
  • Pneumoconioses: pathological findings and differential diagnosis, in particular silicosis and asbestosis. (unibo.it)
  • 9. Pathology of mesothelioma, subtypes and rare variants: What is the role of immunohistochemical markers in differential diagnosis? (stanford.edu)
  • This report updates the 2006 CDC recommendations on the diagnosis and management of tickborne rickettsial diseases in the United States and includes information on the practical aspects of epidemiology, clinical assessment, treatment, laboratory diagnosis, and prevention of tickborne rickettsial diseases. (cdc.gov)
Subtypes4
  • How many molecular subtypes? (wikipedia.org)
  • In the second frame (ORF) K1 of HHV-8 has enabled the identifi cation pattern, dermal vascular channels lined by plump spindle of 5 main HHV-8 molecular subtypes, A-E ( 4 ). (cdc.gov)
  • Pathological subtypes are associated with worse CSS and overall survival (OS) [ 68 ] (LE: 3). (uroweb.org)
  • Despite methodological differences, findings evidence that although IBC presents particular features (lower survival rate and worse prognostics than most types of breast cancer), very few studies examine its epidemiology and specific risk factors in depth and use any other therapeutic approaches than those commonly used for other breast cancer subtypes. (bvsalud.org)
Mechanisms5
  • The Institute for Advanced Biosciences develops fundamental and translational research programs with a focus on understanding the molecular and cellular mechanisms by which cells adapt to the constraints of their environment at all scales of the living (from molecules to ecosystems). (iab-grenoble.fr)
  • The common goal of this interdisciplinary approach is to elucidate the mechanisms by which complex biological and pathological phenotypes emerge and transform along trajectories of health that link environmental exposures, metabolism, infectious diseases and cancer. (iab-grenoble.fr)
  • Three possible mechanisms for this pathology have been suggested: disturbance in immunity, viral infection, and abnormality in the clotting system of blood. (medscape.com)
  • The course therefore aims to provide knowledge of the causes and mechanisms of the diseases and the alterations that derive from them at a tissue, cellular and molecular level. (uninsubria.eu)
  • Further investigation of their regulative roles and interaction may provide new insights into the pathological mechanisms and therapeutic targets for KBD. (nature.com)
Biology2
  • IAB is seeking a visionary scientific leader with internationally recognised strong track record of innovative research in molecular and cellular biology applied to health and medicine, and with strong leadership skills, including prior experience in leadership and management. (iab-grenoble.fr)
  • This 269-paged book on Bovine Tubeculosis covers all aspects of Mycobacterium bovis biology and infection: epidemiological, pathological, microbiological, genomic and immunological together with a comparative approach to the different control schemes being undertaken in different countries. (edu.au)
Immunological2
  • A total of 897 sheep suspected of being infected with TB and belonging to 23 flocks cohabiting with TB-infected cattle herds and/or goats were tested between 2009 and 2013 in Galicia (north-western Spain), using pathological, immunological and molecular techniques. (visavet.es)
  • Diisocyanates, highly reactive low asthma have demonstrated an immunological basis for the molecular weight chemicals, are the leading cause of disease. (cdc.gov)
Epidemiological2
  • This unique epidemiological dataset allows the team to investigate the association of breast cancer risk factors and tumor molecular profiles. (bidmc.org)
  • She collaborates with the NHS for molecular pathology epidemiology research, including understanding how epidemiological factors influence the molecular profiles of breast tumors to understand disease progression and survival. (bidmc.org)
Brigham and Wome1
  • The Dana-Farber Cancer Institute, the Division of MPE (Dept of Pathology, Brigham and Women's Hospital), and the MPE Laboratory hosted this event. (harvard.edu)
Department of Epidemiology1
  • 7 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA. (nih.gov)
Histopathology1
  • Detailed disease endpoint phenotyping can be conducted by means of molecular pathology or surrogate histopathology or immunohistochemistry analysis of diseased tissues and cells within GWAS. (wikipedia.org)
Prognosis1
  • Thus all together it gives the user information about molecular changes such as mutations, fusion genes, and numerical chromosome to estimate or show the prognosis and to choose the best treatment. (expertconferences.org)
Genomics1
  • New and emerging disciplines and concepts such as molecular pathological epidemiology, social genomics and other "systems-thinking" methods provide a more comprehensive view of the entire subject of aging, and study its indivisible bonds with the environment, society and culture. (oaepublish.com)
Biomarkers1
  • Several chapters focus on new trends in the field, e.g. immune therapy and identification of biomarkers, molecular oncogenesis including genetic susceptibility, and molecular diagnostic pathology. (stanford.edu)
Biostatistics1
  • 17 Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC 3000, Australia. (nih.gov)
Diagnostics2
  • Since molecular diagnostics is becoming routine clinical practice, molecular pathology data can aid epidemiologic research. (wikipedia.org)
  • Expert Review of Molecular Diagnostics. (wikipedia.org)
Alterations4
  • Diagnostic criteria, pathological features, and genetic and other associated molecular alterations are described in a disease-oriented manner. (iarc.fr)
  • This led us to investigate whether FXI deficiency in elderly ApoE knockout (KO) mice would decrease pathological alterations compatible with atherosclerosis and AD. (spandidos-publications.com)
  • However, neither atherosclerosis nor AD‑associated pathological alterations in the elderly mice brains were observed in either the DKO mice or the ApoE KO mice. (spandidos-publications.com)
  • 3 The development of molecular targeted therapies aimed at these molecular alterations has generated great optimism for the treatment of cancers such as NSCLC, and drugs targeting the EGFR tyrosine kinase domain are now available. (bmj.com)
General Pathology1
  • One can not understand specific organ systems disorders if the knowledge of General Pathology is missing. (unibo.it)
Intestinal pathology4
  • A proportion of each stool was used to carry various point-of-care diagnostic analyses including Kato-Katz faecal microscopy and QUIK CHEK rapid diagnostic tests (RDTs) to diagnose infection with giardiasis, and faecal occult blood / faecal calprotectin RDTs to assess the presence of overt blood and calprotectin within the stool (a measure of intestinal pathology). (beds.ac.uk)
  • However, the correlation between malaria intestinal pathology and intestinal microbiota has not been investigated. (nature.com)
  • By contrast, BALB/c mice are resistant to ECM and exhibit milder intestinal pathology and dysbiosis. (nature.com)
  • These results indicate that the severity of cerebral and intestinal pathology coincides with the degree of alteration in microbiota. (nature.com)
Phenotypes1
  • The molecular basis of breast cancer pathological phenotypes. (bidmc.org)
Mutations1
  • The possibility of mutations of RAS signaling genes and/or TP53 in combination as a negative prognostic impact on pathological stage I non-small cell lung cancer. (cdc.gov)
20221
  • Epidemiology of Renal Cell Carcinoma: 2022 Update. (who.int)
Cellular2
  • In this era of personalized medicine and personalized prevention, we need integrated science (such as MPE) which can decipher diseases at the molecular, genetic, cellular, and population levels simultaneously. (elsevierpure.com)
  • Define The Molecular And Cellular Bases Of Physiological Regulation And Cell Signaling. (uaeu.ac.ae)
Prognostic1
  • Exploring the molecular features and genetic prognostic factors of pulmonary high-grade neuroendocrine carcinomas. (cdc.gov)
Interdisciplinary1
  • The use of molecular pathology in epidemiology lacked standardized methodologies and guidelines as well as interdisciplinary experts and training programs. (wikipedia.org)
Ogino1
  • The term "molecular pathological epidemiology" was used by Shuji Ogino and Meir Stampfer in 2010. (wikipedia.org)
20171
  • She joined the Department of Pathology faculty as Instructor in 2015, and was promoted to Assistant Professor in 2017. (bidmc.org)
Assessment1
  • A proportion of each stool was also stored in ethanol for transportation to the Liverpool School of Tropical Medicine (LSTM) for future DNA extraction and molecular assessment. (beds.ac.uk)
Prevention2
  • The main translational endpoints are cancers, infectious diseases (bacteria, fungi, viruses and parasites), fertility and development pathologies and prevention of environmental exposures in early life. (iab-grenoble.fr)
  • The fundamental goal of B.Nadel's laboratory is to contribute to cancer prevention, monitoring, and therapy, through the study of the pathological deregulations of lymphocyte differentiation. (univ-mrs.fr)
Analyses3
  • We are proud to work together with the leading biotech company in Sweden for biomarker panel analyses in epidemiology, OLINK Proteomics AB, Uppsala, and its representatives! (lu.se)
  • Molecular characterization-based multi-omics analyses in primary liver cancer using the Japanese version of the genome atlas. (cdc.gov)
  • Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow. (cdc.gov)
Diseases1
  • The pathological and clinical characteristics of kuru that distinguish it from other PrP diseases in humans are also discussed. (medscape.com)
Methodologies1
  • This review presents an overview of the current methodologies used to identify such molecular markers. (bmj.com)
Risk factors3
  • citation needed] MPE began as analysis of risk factors (e.g., smoking) and molecular pathological findings (e.g. (wikipedia.org)
  • As a result, social epidemiology includes the study of the social context in which the health-disease phenomena occurs in addition to the investigation of individual risk factors. (conferenceseries.com)
  • In this study, we sought to assess the epidemiology of GC, its clinicopathological profiles, and its association with risk factors as well as to identify premalignant gastric lesions (PGL) and examine neoplastic progression. (mdpi.com)
Tumors1
Pathways1
  • This study was designed to identify signaling pathways and crucial proteins involved in the pathological mechanism of KBD compared with osteoarthritis (OA). (nature.com)
Research4
  • 3 Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. (nih.gov)
  • 2. Asbestos and mesothelioma: What is recent advance in research on asbestos-induced molecular carcinogenesis? (stanford.edu)
  • IAB develops translational and pre-clinical research programs in partnership with CHU Grenoble-Alpes and actively cooperates with other research centers of the Grenoble site, in particular ESRF, EMBL, IBS and molecular chemistry/pharmacochemistry and physics departments of UGA. (iab-grenoble.fr)
  • Research activities at the are University contributed to the generalizable knowledge at the national and regional level by: (i) addressing cultural context of medical practices (ii) studding frequent (pathologies pregnancy, diabetes, cancer) and rare (Vest syndrome, pediatric arterial ischemic stroke) disease/health conditions, (iii) being involved in the International, multicenter research projects (e.g. (dtmu.ge)
Cancer5
  • citation needed] Studies to examine the relationship between an exposure and molecular pathological signatures of disease (particularly, cancer) became increasingly common throughout the 1990s and early 2000s. (wikipedia.org)
  • 23 Leeds Institute of Cancer and Pathology, University of Leeds, Leeds LS2 9JT, UK. (nih.gov)
  • This volume updates the existing ICD-O codes and provides new codes for use in epidemiology and cancer registration. (iarc.fr)
  • Molecular Diagnostic and Prognostication Assays for the Subtyping of Urinary Bladder Cancer Are on the Way to Illuminating Our Vision. (who.int)
  • Background: The epidemiology of human papillomavirus (HPV) infection and the pattern of HPV genotype distribution are parameters needed to assess the risk of cervical cancer. (bvsalud.org)
Abstract1
Immunohistochemistry1
  • In turn, it discusses recent molecular pathological studies on mesothelioma, which claim to offer more accurate classifications than traditional morphology and immunohistochemistry-based approaches. (stanford.edu)
Anatomy1
  • Full knowledge of normal anatomy, histology and embriology are necessary to understand Anatomic Pathology. (unibo.it)
Encompasses1
Tissue3
  • Typically, MPE utilizes tissue pathology resources and data within existing epidemiology studies. (wikipedia.org)
  • Topics discussed during lectures represent an integral part of the program and are the subject of evaluation during exams, including knowledge of tissue fixation and of pathology reporting (biopsies, surgical specimens, autopsies). (unibo.it)
  • The methods necessary for the processing of tissue samples and for the diagnostic procedures of Anatomic Pathology. (unibo.it)
Frequent1
  • 14. Frequent NF2 inactivation in mesothelioma: How can we treat mesothelioma with targeted therapies for molecular aberrations? (stanford.edu)
Tumor1
  • We studied 5 consecutive cases of GCT involving the distal radius operated by en-bloc resection of tumor followed by reconstruction with ipsilateral non-vascularized fibular graft with a minimum 1 year follow-up. (jbstjournal.com)
Faculty1
Classification1
  • There have been particularly substantial changes to the classification of conjunctival neoplasia and melanoma, based on the latest information from genetic and molecular studies. (iarc.fr)