• Diseases
  • Th1 cells produce cytokines (interferon (IFN)-gamma, interleukin (IL)-2, tumour-necrosis factor (TNF)-alpha and lymphotoxin) that are commonly associated with cell-mediated immune responses against intracellular pathogens, delayed-type hypersensitivity reactions, and induction of organ-specific autoimmune diseases. (jove.com)
  • Th2 cells produce cytokines (IL-4, IL-10 and IL-13) that are crucial for control of extracellular helminthic infections and promote atopic and allergic diseases. (jove.com)
  • This list of autoimmune diseases is categorized by organ and tissue type to help locate diseases that may be similar. (wikipedia.org)
  • This list includes conditions that are not diseases but signs common to autoimmune disease. (wikipedia.org)
  • These conditions are included here because they are frequently listed as autoimmune diseases but should not be included in the list above until there is more consistent evidence. (wikipedia.org)
  • Before moving a condition from here to the list of autoimmune diseases, references should be provided in the Wikipedia page for the condition that point to evidence, direct or indirect, that it is an autoimmune disease. (wikipedia.org)
  • 2014). The autoimmune diseases (Fifth ed. (wikipedia.org)
  • December 1997), "Subacute bacterial endocarditis masquerading as type III essential mixed", Journal of the American Society of Nephrology, 8 (12): 1971-6, PMID 9402102 Autoimmune Diseases at the US National Library of Medicine Medical Subject Headings (MeSH) Kárpáti F, Dénes L, Büttner K (1975). (wikipedia.org)
  • Shown to be potent Th1-like adjuvants, stimulatory CpG motifs are currently used as effective therapeutic vaccines for various animal models of infectious diseases, tumors, allergies, and autoimmune diseases. (jove.com)
  • The development of sensitive immunochemical diagnosis for three autoimmune neurological diseases ( MG, NMO and LEMS ). (pasteur.gr)
  • Insults to neurons in the central nervous system caused by infection, trauma, ischemia, stroke, autoimmune responses, or other neurodegenerative diseases may cause reactive astrocytes. (wikipedia.org)
  • For example, some diseases like Susac's syndrome (MS has an important vascular component), leukoaraiosis, myalgic encephalomyelitis (aka chronic fatigue syndrome) or autoimmune variants of peripheral neuropathies like Guillain-Barré syndrome or progressive inflammatory neuropathy could be included assuming the autoimmune model. (wikipedia.org)
  • disease
  • Th1-specific Cell Surface Protein Tim-3 Regulates Macrophage Activation and Severity of an Autoimmune Disease Nature. (jove.com)
  • These conditions are included here because: The disease was listed in the prior version of this table The disease is included in several widely used lists of autoimmune disease and is shown here to ensure that a person visiting this page does not conclude that the disease was not considered. (wikipedia.org)
  • In this study, we show that the application of an immunomodulatory GpG ODN, with a single base switch from CpG to GpG, can effectively inhibit the activation of Th1 T cells associated with autoimmune disease. (jove.com)
  • It is the main autoantigen in the autoimmune disease myasthenia gravis ( MG ), while its mutations cause congenital myasthenic syndromes. (pasteur.gr)
  • pore
  • For example, the aquaporin 3 channel has a pore width of 8-10 Ångströms and allows the passage of hydrophilic molecules ranging between 150 and 200 Da. (wikipedia.org)
  • Potassium
  • The 2003 Nobel Prize in Chemistry was awarded jointly to Peter Agre for the discovery of aquaporins, and Roderick MacKinnon for his work on the structure and mechanism of potassium channels. (wikipedia.org)
  • Humans
  • Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. (jove.com)
  • cells
  • The cell membranes of a variety of different bacteria, fungi, animal and plant cells contain aquaporins through which water can flow more rapidly into and out of the cell than by diffusing through the phospholipid bilayer. (wikipedia.org)
  • Water moves through cells in an organized way, most rapidly in tissues that have aquaporin water channels. (wikipedia.org)
  • therapies
  • Pubmed ID: 16153891 Experimental autoimmune encephalomyelitis (EAE) is a useful model for aiding the development of new treatments for MS. All therapies approved for MS ameliorate EAE. (jove.com)
  • Activation
  • They are called pre-active lesions in its initial stage and they do not show autoimmune infiltrates at this stage They show microglia activation and degeneration of the neuron axons without T-cell infiltration. (wikipedia.org)
  • development
  • Referring to MS, the physiology refers to the different processes that lead to the development of the lesions and the pathology refers to the condition associated with the lesions. (wikipedia.org)