• She is also well known for her seminal descriptions of multiple soft tissue tumors, such as epithelioid hemangioendothelioma and pleomorphic hyalinizing angiectatic tumor of soft parts ("PHAT" which is categorized as a rare and locally aggressive neoplasm occurring in the lower extremities of a patient) among others. (wikipedia.org)
  • [ 13 ] The WWTR1-CAMTA1 fusion was used in a retrospective study with good results to reinforce prior data that epithelioid hemangiomas are benign lesions and not low-grade malignant soft-tissue tumors. (medscape.com)
  • Malignant vascular tumors: Epithelioid Hemangioendothelioma. (neoplasiaresearch.com)
  • Their behavior ranges from that of indolent, low-grade tumors, such as epithelioid hemangioendothelioma, to that of lethal, high-grade angiosarcomas or hemangiopericytomas. (basicmedicalkey.com)
  • Hemangioendothelioma is a vascular tumor with several different morphologic patterns that can include a component of ovoid or spindled cells, but generally lacks an inflammatory component. (neoplasiaresearch.com)
  • Pathologic quiz case: incidental hepatic nodule on abdominal laparotomy. (uchicago.edu)
  • Hepatic angiosarcomas and epithelioid hemangioendotheliomas can be easily overseen in liver biopsies, if they spread along the sinusoids without detoriation of the acinar architecture and without significant alteration of the surrounding liver cell plates. (springer.com)
  • Perisinusoidal fibrosis can be caused by intrasinusoidal accumulation of pathologic cells, advanced intrasinusoidal macrophagocytic storage diseases and by activation of the vitamin A-storing hepatic stellate cells. (springer.com)
  • Hepatic epithelioid hemangioendothelioma: An international multicenter study. (clinic.cat)
  • Despite the rich vascularity of bone, skeletal vascular lesions are rare, and consequently knowledge of their clinical and pathologic features is still limited. (basicmedicalkey.com)
  • Treatment is usually immobilization for proximal humerus lesions with pathologic fracture. (orthobullets.com)
  • An open-label, multicenter, phase II study of bevacizumab for the treatment of angiosarcoma and epithelioid hemangioendotheliomas. (uchicago.edu)
  • Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. (uchicago.edu)
  • We present a challenging lymphocyte-rich soft tissue lesion that was not recognized to be an unusual hemangioendothelioma until after several recurrences in the arm of a 63 year-old male, which was originally diagnosed as a follicular dendritic cell tumor instead. (neoplasiaresearch.com)
  • The standard vascular markers used in pathologic differential diagnosis of vascular conditions include von Willebrand factor (vWF), factor VIII-associated protein, platelet endothelial cell adhesion molecule-1 (CD31), human hematopoietic progenitor cell antigen (CD34), v- ets avian erythroblastosis virus E26 oncogene homolog (ERG), human herpes virus 8 (HHV-8), latency-associated nuclear antigen (LANA1), podoplanin (D2-40), and PROX1. (basicmedicalkey.com)
  • Histologic evaluation of the thyroid nodule showed multinodular proliferation of oval to polygonal-shaped epithelioid cells with oval nuclei and eosinophilic cytoplasm arranged in sheet- or cord-like patterns, accompanied by fibrous stroma and marked osseous metaplasia. (springeropen.com)
  • Cutaneous biopsy revealed RAE characterized by the proliferation of epithelioid and spindle-shaped cells in superficial and middermis lining vascular channels, arranged in clusters, and sometimes displaying an intravascular growth pattern. (thedoctorsdoctor.com)
  • Clinical patterns and outcome in epithelioid hemangioendothelioma with or without pulmonary involvement: insights from an internet registry in the study of a rare cancer. (uchicago.edu)
  • Surgical curettage and bone grafting is indicated for pathologic fractures that have a high rate of refracture and malunion. (orthobullets.com)
  • The most recent tumor consisted predominantly of epithelioid spindled cells with moderate amounts of bubbly pale to eosinophilic cytoplasm with rare discrete cytoplasmic vacuoles, admixed with a prominent lymphoid infiltrate and occasional erythrocytes. (neoplasiaresearch.com)
  • The radiologic images/reports and pathologic materials from all patients were reviewed. (unibas.ch)
  • This graph shows the total number of publications written about "Hemangioendothelioma, Epithelioid" by people in this website by year, and whether "Hemangioendothelioma, Epithelioid" was a major or minor topic of these publications. (uchicago.edu)
  • [ 12 ] Identification of WWTR1-CAMTA1 fusion as the genetic hallmark of epithelioid hemangioendothelioma, regardless of anatomic location, provides an objective and powerful diagnostic tool that can be used to distinguish the two entities. (medscape.com)
  • She is also well known for her seminal descriptions of multiple soft tissue tumors, such as epithelioid hemangioendothelioma and pleomorphic hyalinizing angiectatic tumor of soft parts ("PHAT" which is categorized as a rare and locally aggressive neoplasm occurring in the lower extremities of a patient) among others. (wikipedia.org)
  • Rarely, hemangiomas may be associated with other pathologic processes, such as the consumptive coagulopathy of Kasabach-Merritt syndrome and tumor-induced osteomalacia. (medscape.com)
  • Some have argued that epithelioid hemangiomas are not a distinct clinicopathologic entity but rather a misdiagnosed hemangioendothelioma, which is a tumor with malignant potential, unlike hemangioma. (medscape.com)
  • Report of a case with radiologic-pathologic correlation. (nih.gov)
  • From the archives of the AFIP: primary vascular neoplasms of the spleen: radiologic-pathologic correlation. (nih.gov)
  • 24. [Epithelioid hemangioendothelioma: a clinicopathologic analysis of 13 cases]. (nih.gov)
  • Despite a common theme of vascular origin, the pathologic and imaging appearance of these entities can be heterogeneous. (johnshopkins.edu)
  • 40. Metastatic hepatic epithelioid hemangio-endothelioma: long-term response to sunitinib malate. (nih.gov)
  • 12] Identification of WWTR1-CAMTA1 fusion as the genetic hallmark of epithelioid hemangioendothelioma, regardless of anatomic location, provides an objective and powerful diagnostic tool that can be used to distinguish the two entities. (medscape.com)
  • Clinical characteristics of epithelioid hemangioendothelioma: a single-center retrospective study. (nih.gov)