Neurodegenerative DiseasesDisease SusceptibilityGenetic Predisposition to DiseasePolymorphism, Single NucleotideGenetic LociGenotypeNerve DegenerationAlzheimer DiseaseBrainDisease Models, AnimalMutationPolymorphism, GeneticNeuronsAllelesAmyotrophic Lateral SclerosisChromosome MappingHaplotypesHuntington DiseaseParkinson Diseasetau ProteinsGenome-Wide Association Studyalpha-SynucleinPhenotypeGenetic LinkageGene FrequencyQuantitative Trait LociGenetic VariationCase-Control StudiesMice, TransgenicMolecular Sequence DataNerve Tissue ProteinsGenetic MarkersLinkage DisequilibriumPrionsMice, Inbred C57BLPrion DiseasesNeuroprotective AgentsTauopathiesInclusion BodiesHeredodegenerative Disorders, Nervous SystemProteostasis DeficienciesMicrogliaCells, CulturedOxidative StressGenome, HumanMicrobial Sensitivity TestsModels, GeneticGene Expression RegulationAmyloid beta-PeptidesSynucleinsCell DeathBase SequenceAmino Acid SequenceSignal TransductionSpinocerebellar AtaxiasPedigreeMicrosatellite RepeatsAgingFrontotemporal Lobar DegenerationImmunity, InnateMice, KnockoutMitochondriaModels, BiologicalGenetic Association StudiesTrinucleotide Repeat ExpansionHLA-DQ AntigensCrohn DiseaseFriedreich AtaxiaCell LineFrontotemporal DementiaPolymerase Chain ReactionCrosses, GeneticAutophagyNod2 Signaling Adaptor ProteinHLA-DRB1 ChainsSequence Analysis, DNAEpistasis, GeneticHLA-DQ beta-ChainsHLA-DR AntigensPlant DiseasesAmyloidHLA-DR3 AntigenPeptidesGene Expression ProfilingNeuronal Ceroid-LipofuscinosesComplement C4aGuamRNA, MessengerAnti-Bacterial AgentsAge of OnsetGenetic Diseases, InbornApoptosisSuperoxide DismutaseSpecies SpecificityLod ScoreProtein FoldingGenetic TestingAstrocytesAutoimmune DiseasesTime Factors