Pasteurella multocida. Medical search. Frequent questions

Pulsed-field gel electrophoresis profiles of Apa I (A) and Sma I (B) digested genomic DNA of Pasteurella multocida isolates from an 83-year-old man with a urinary tract infection (lane 1) and his pet dog (lane 2). (cdc.gov)
This model is useful for studying the pathogenicity of other P. multocida type A isolates in the specific pig host. (biomedcentral.com)
Antimicrobial resistance among Pasteurella isolates is rarely reported in humans. (medscape.com)
Molecular Characterization of Pasteurella multocida Isolates that Caus" by Apasara Worarach, Gumtorn Promto et al. (chula.ac.th)
In this study, serological typing, minimum inhibitory concentration (MIC) and pulsed-field gel electrophoresis (PFGE) were used to characterize 87 HS isolates caused by P. multocida from cattle and buffaloes during 1989 to 2011 in comparison with Thai and Laotian vaccine strains and the reference P. multocida strain P1256. (chula.ac.th)
In conclusion, a remarkable homogeneity was observed among the HS isolates caused by P. multocida in Thailand over the past 22 years. (chula.ac.th)
Here, the susceptibility of Mannheimia haemolytica and Pasteurella multicoda isolates obtained from BRD clinical cases (deep lung swabs at post-mortem) among feedlots in four Australian states (2014-2019) was determined for 19 antimicrobial agents. (edu.au)
Five P. multocida isolates (3.6%), all obtained from NSW in 2019, exhibited dual resistance to macrolides and tetracycline, and a further two Queensland isolates from 2019 (1.4%) exhibited a multidrug-resistant phenotype to ampicillin/penicillin, tetracycline, and tilmicosin. (edu.au)
Random-amplified polymorphic DNA (RAPD) typing identified a high degree of genetic homogeneity among the M. haemolytica isolates, whereas P. multocida isolates were more heterogeneous. (edu.au)
To achieve this, we briefly investigated 158 P. multocida isolates from pigs with respiratory disorders in China between 2019 and 2020. (biomedcentral.com)
Previously, two serotyping systems were developed based on the bacterial capsular antigens or the lipopolysaccharide (LPS) antigens which assigned P. multocida isolates into five serogroups (A, B, D, E and F) (Carter 1955 ) and/or 16 serovars (serovars 1 ~ 16), respectively (Heddleston et al. (biomedcentral.com)
Therefore, we undertook a separate project to determine the current profiles of capsular: LPS genotypes of P. multocida isolates in pigs of China in recent years. (biomedcentral.com)
To understand the capsular genotypes and LPS genotypes of swine P. multocida prevalent in pig farms of China, we investigated 158 P. multocida isolates recovered from 1371 nasal swabs and/or lungs of pigs with respiratory disorders in pig farms from 16 provinces of China between September 1, 2019 and December 12, 2020 in this study. (biomedcentral.com)
Things took an unexpected turn when isolates from our samples sent to South Africa for culture appeared to be P. multocida but failed to react with any of the four capsular types for this bacterium. (springernature.com)

Patients with a joint replacement (perhaps notably knee replacement) in place may, in particular, be at risk of secondary infection of that joint during an episode of P multocida cellulitis/bacteraemia. (wikipedia.org)
Diagnosis of the bacterium in humans was traditionally based on clinical findings, and culture and serological testing, but false negatives have been a problem due to easy death of P. multocida, and serology cannot differentiate between current infection and previous exposure. (wikipedia.org)
Patients with P multocida infection who present without evidence of an animal bite are more likely to have invasive infection such as respiratory or bloodstream infection. (medscape.com)
P multocida infection usually presents as an infection that complicates an animal bite or injury. (medscape.com)

P. multocida is the cause of a range of diseases in mammals and birds, including fowl cholera in poultry, atrophic rhinitis in pigs, and bovine hemorrhagic septicemia in cattle and buffalo. (wikipedia.org)
P. multocida strains that cause fowl cholera in poultry typically belong to the serovars 1, 3, and 4. (wikipedia.org)
Pasteurella multocida causes fowl cholera in turkeys. (usda.gov)
Fowl cholera is a contagious, bacterial disease of birds caused by Pasteurella multocida . (merckvetmanual.com)
Pasteurella multocida , the causal agent of fowl cholera, is a small, gram-negative, nonmotile rod with a capsule that may exhibit pleomorphism after repeated subculture. (merckvetmanual.com)
Although P multocida may infect a wide variety of animals, strains isolated from nonavian hosts generally do not produce fowl cholera. (merckvetmanual.com)

Pasteurella multocida causes haemorrhagic septicaemia (HS), which is a severe epidemic disease in cattle and buffaloes. (chula.ac.th)
Background: Pasteurella multocida B:2 causes haemorrhagic septicaemia in cattle and buffaloes. (unair.ac.id)
We performed a variety of laboratory tests and found no evidence that other bacteria, viruses, or toxins were underlying the pathology we observed, and started writing up a draft manuscript of our findings on haemorrhagic septicaemia caused by P. multocida . (springernature.com)

Strains that cause atrophic rhinitis in pigs are unique as they also have P. multocida toxin (PMT) residing on a bacteriophage. (wikipedia.org)
The use of theBacillus subtilis sacB gene as a counter-selectable marker was assessed in serogroup A and B strains ofPasteurella multocida. (monash.edu)
Thus, the objective of the present study was to investigate the capacity of eight P. multocida type A field strains to cause disease in healthy pigs. (biomedcentral.com)
Other macrolides, including azithromycin, clarithromycin, and telithromycin (in order of decreasing susceptibility), retain in vitro activity against most Pasteurella strains. (medscape.com)

Uracil-DNA glycosylase (Pasteurella multocida subsp. (nih.gov)
Regulon of IscR in Pasteurella multocida subsp. (lbl.gov)
species= Pasteurella multocida subsp. (lbl.gov)

Nevertheless, Pasteurella species commonly are isolated pathogens in most animal bites, especially in dog- and cat-related injuries. (medscape.com)
Mannheimia haemolytica , the bacteria most frequently isolated from pneumonic lungs in cattle, and Pasteurella multocida often compound respiratory disease initiated by other pathogens (viruses, bacteria, mycoplasma). (thecattlesite.com)
The new tetracycline-derivative tigecycline also has excellent in vitro activity against P multocida and other pathogens encountered in animal and bite injuries. (medscape.com)
Bovine Pasteurella multocida serogroup A (bovine PmA) is one of the most important pathogens causing fatal pneumonia in cattle. (figshare.com)
Animal bites usually contain multiple potential pathogens, including Pasteurella multocida (particularly in cat bites), staphylococci, streptococci, and anaerobes. (msdmanuals.com)

Bovine respiratory disease (BRD) associated with either Mannheimia haemolytica or Pasteurella multocida is often due to secondary bacterial invasion by these organisms. (thecattlesite.com)
Two bacteria, Mannheimia haemolytica (f Pasteurella haemolytica) and Pasteurella multocida , are often associated with bovine respiratory disease (BRD) or shipping fever in cattle and are often referred to as secondary bacterial invaders. (thecattlesite.com)

Pneumonia associated with either Mannheimia haemolytica or P asteurella multocida often occurs when the animal's normal defenses are compromised. (thecattlesite.com)
M. haemolytica is often associated with the more acute cases of BRD, while P. multocida is often associated with the longer-lasting cases of BRD. (thecattlesite.com)
These results confirm the first emergence of AMR in M. haemolytica and P. multocida from BRD cases in Australia, which should be closely monitored. (edu.au)

P multocida can be subgrouped by capsule serogroup antigens into five capsular types (A, B, C, D, and F) and into 16 somatic serotypes. (merckvetmanual.com)

Pasteurella multocida capsular type A ( P. multocida type A) is one of the most common agents associated with bronchopneumonia in pigs [ 1 ]. (biomedcentral.com)
Collectively, these data indicate that P. multocida adhesion to TPBM is promoted by capsular hyaluronic acid and can be upregulated by maturation on ECL matrix or following hyaluronidase treatment. (usda.gov)

P multocida often exists as a commensal in the upper respiratory tracts of many livestock, poultry, and domestic pet species, especially cats and dogs. (medscape.com)
In fact, Pasteurella species are some of the most prevalent commensal bacteria present in domestic and wild animals worldwide. (medscape.com)
Fortunately, Pasteurella species are fairly sensitive organisms and can be treated with a penicillin-based regimen. (medscape.com)
Approximately 20 different species of the genus Pasteurella have been identified using phenotypic and genetic analyses. (cabi.org)
1972 ). The application of these two serotyping systems in epidemiological studies has helped to address the serotypes of P. multocida circulating in different host species and their correlations to the diseases caused by the agent, thereby contributing to the vaccine development (Singh et al. (biomedcentral.com)
Here the authors show that six elephants died of bacterial septicaemia associated with a little-reported Pasteurella species. (springernature.com)

In humans, P. multocida is the most common cause of wound infections after dog or cat bites. (wikipedia.org)
Title : Pasteurella Multocida Infections In 16 Persons In Oregon Personal Author(s) : Holmes, M. A.;Brandon, G. (cdc.gov)
We report 2 cases of severe infections due to Pasteurella multocida, both occurring during pregnancy in previously healthy women. (lu.se)
The duration of therapy for P multocida infections has not been well established and can be tailored to clinical response. (medscape.com)
Pasteurella can cause a wide spectrum of diseases from local infections to septic shock. (medscape.com)

Pasteurella multocida is a Gram-negative, nonmotile, penicillin-sensitive coccobacillus of the family Pasteurellaceae. (wikipedia.org)
Pasteurella multocida is a small, gram-negative, nonmotile, non-spore-forming coccobacillus with bipolar staining features. (medscape.com)
Pasteurella is a Gram-negative coccobacillus that causes a wide spectrum of diseases in humans and is commonly transmitted from cat and dog bites. (medscape.com)
Pasteurella multocida is small Gram-negative coccobacillus that is a component of the upper respiratory tract and gastrointestinal flora of many animals. (medscape.com)

The P. multocida serotype-1 is most associated with avian cholera in North America, but the bacterium does not linger in wetlands for extended periods of time. (wikipedia.org)
Genome sequence of Pasteurella multocida Razi 0002 of avian origin. (pacb.com)
We report here on the genome sequence of Pasteurella multocida Razi 0002 of avian origin, isolated in Iran. (pacb.com)

This disease, caused by the bacterium Pasteurella multocida , is seen most commonly in cattle and water buffalo. (springernature.com)

All rats were subcutaneous inoculated once with 108cfu/ml of Pasteurella multocida strain PMB 202. (medwelljournals.com)
The reference P. multocida strain P1256 belonged to PFGE type 2. (chula.ac.th)

Now 5 years have passed by, considering the distribution and prevalence of P. multocida serotypes (or genotypes) may vary considerably over time in a given region (Tang et al. (biomedcentral.com)

Pasteurella multocida is a multiple host gram-negative pathogen and a leading cause of pig respiratory disorders in the world (Peng et al. (biomedcentral.com)

This study was designed to understand the genotypical and antimicrobial resistant characteristics of P. multocida from pigs in China. (biomedcentral.com)
This study contributes to the understanding of genotypes and antimicrobial resistance profile of P. multocida currently circulation in pigs of China. (biomedcentral.com)

Pasteurella multocida toxin (PMT, produced by Pasteurella multocida ) offers the possibility to discriminate between Gα q and Gα 11 proteins, since it stimulates inositol phosphate formation in a strictly Gα q -dependent manner. (sigmaaldrich.com)

Pasteurella multocida type A (PmA) is considered a secondary agent of pneumonia in pigs. (biomedcentral.com)
According to Ross [ 6 ], the difficulty of reproducing the disease in the absence of infectious or noninfectious cofactors is a major limitation to demonstrating the primary role of P. multocida type A in pneumonic lesions in pigs. (biomedcentral.com)
Pasteurella multocida is a leading cause of respiratory disorders in pigs. (biomedcentral.com)

According to the results, it seems that E. purpurea extract has an immunomodulatory effect and can be used to prevent or control of pneumonia caused by Pasteurella. (ac.ir)

The LPS produced by P. multocida consists of a hydrophobic lipid A molecule (that anchors the LPS to the outer membrane), an inner core, and an outer core, both consisting of a series of sugars linked in a specific way. (wikipedia.org)
Turbidimetric assessments of batch cultural growth kinetics revealed the outer membrane permeabilizer polymyxin B nonapeptide sensitized Pseudomonas aeruginosa and Escherichia coli to the hydrophobic probe novobiocin, whereas little or no sensitization was observed for two surface hydrophobicity variants of Pasteurella multocida. (okstate.edu)
A hydrocarbon adherence assay revealed permeabilizing concentrations of polymyxin B nonapeptide increased cell surface hydrophobicity of P. aeruginosa and the hydrophobic P. multocida variant, while E. coli and the hydrophilic P. multocida variant remained unaffected. (okstate.edu)

P multocida pyelonephritis, renal abscess, epididymitis , and cervicitis have been reported in rare cases. (medscape.com)

P multocida rarely causes gastrointestinal problems but has been associated with appendicitis, hepatosplenic abscesses, and spontaneous bacterial peritonitis . (medscape.com)
By screening the different metabolites between high (lung)- and low (liver)-bacterial density tissues, the present work revealed that L-ascorbic acid and L-aspartic acid directly influenced bovine P. multocida growth. (figshare.com)

[ 18 ] P multocida meningitis has been associated with cat licks and bites occurring on the face in persons at the extremes of age. (medscape.com)

The survival of P. multocida bacteria has also been shown to be increased by the addition of salt into their environments. (wikipedia.org)

Empiric antibiotics for outpatient treatment usually include monotherapy with amoxicillin/clavulanate 500 mg orally 3 times a day or combined therapy with penicillin 500 mg orally 4 times a day (for E. corrodens, P. multocida, streptococci, and anaerobes) plus either a cephalosporin (eg, cephalexin 500 mg orally 4 times a day) or semisynthetic penicillin (eg, dicloxacillin 500 mg orally 4 times a day) for staphylococci. (msdmanuals.com)

Pasteurella is the most common organism isolated from cat and dog bites. (medscape.com)

Studies have shown a mortality range from 7 to 31% in Pasteurella bacteremia. (medscape.com)

If P multocida is the only isolated organism, therapy may be changed to intravenous penicillin G. Once clinical improvement is noted, oral penicillin VK is an option. (medscape.com)

P. multocida expresses a range of virulence factors including a polysaccharide capsule and the variable carbohydrate surface molecule, lipopolysaccharide (LPS). (wikipedia.org)
So far, limited study has been conducted to evaluate the response of endothelial cells of buffalo towards P. multocida B:2 and its lipopolysaccharide (LPS). (unair.ac.id)

See: Pasteurellosis P. multocida causes a range of diseases in wild and domesticated animals, as well as humans. (wikipedia.org)

Conclusions: This study revealed that both whole cells P. multocida B:2 and LPS endotoxin showed similar moderate to severe cellular damage, but whole-cell P. multocida B:2 appeared to be more potent in causing much severe damage than LPS alone. (unair.ac.id)

This study aimed to evaluate the ultrastructural changes in the aortic endothelium of buffaloes (BAEC) following exposure to P. multocida B:2 and its endotoxin. (unair.ac.id)

Pasteurella multocida was first found in 1878 in cholera-infected birds. (wikipedia.org)
Dissemination of P multocida within a flock and between houses is primarily by excretions from the mouth, nose, and conjunctiva of diseased birds that contaminate their environment. (merckvetmanual.com)

She was found to have Pasteurella multocida bacteremia. (medscape.com)
P. multocida is often found in the mouths of healthy animals but can become pathogenic under certain circumstances - like when it killed around 200,000 endangered saiga antelope in Kazakhstan in 2015. (springernature.com)

Used to prevent More than 2 months of chicken and More than 1 months of duck Of Pasteurella Multocida disease. (veterinarypoultrymedicine.com)

P. multocida has been observed invading and replicating inside host amoebae, causing lysis in the host. (wikipedia.org)

Anatomy4

Organisms17

Diseases14

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Information Science1

Isolates14

Infection4

Fowl cholera6

Haemorrhagic septicaemia3

Strains4

Subsp3

Pathogens5

Respiratory disease2

Haemolytica3

Serogroup1

Capsular2

Species6

Infections5

Coccobacillus4

Avian3

Cattle1

Strain2

Serotypes1

Gram-negative1

Antimicrobial2

Toxin1

Pigs3

Pneumonia1

Hydrophobic3

Abscess1

Bacterial2

Meningitis1

Bacteria1

Antibiotics1

Bites1

Mortality1

Organism1

Lipopolysaccharide2

Humans1

Severe1

Buffaloes1

Birds2

Found2

Disease1

Host1