Particles lipoproteins. Medical search. Frequent questions

A major proportion of triglycerides in plasma triglyceride-rich lipoproteins (TRL) are removed in peripheral tissues by lipoprotein lipase, and hypothetically a minor proportion can also be removed by whole-lipoprotein particle uptake. (ox.ac.uk)
As more and more triglycerides are removed from the VLDL because of the action of LPL and CETP enzymes, the composition of the molecule changes, and it becomes intermediate-density lipoprotein (IDL). (wikipedia.org)
Triglycerides in intermediate-density lipoprotein (IDL-TG) increased only in the CBCR group (p = 0.043). (biosferteslab.com)
12-hour fasting recommended: Elevated triglycerides can interfere with accurate measurements of lipoprotein particle size and number by NMR. (aruplab.com)
Disease activity (DAS28) and plasma lipoproteins concentrations (total, HDL and LDL-cholesterol, triglycerides, ApoA, ApoB) were assessed in 55 RA patients and 55 controls. (bmj.com)
Chylomicrons are very large particles that mainly carry triglycerides (fatty acids from your food). (harvard.edu)
Very-low-density lipoprotein (VLDL) particles also carry triglycerides to tissues. (harvard.edu)
Low-density lipoprotein (LDL) particles are even richer in pure cholesterol, since most of the triglycerides they carried are gone. (harvard.edu)
elevated triglycerides - low high density lipoprotein (HDL) cholesterol - shift in low-density lipoprotein (LDL) particle density towards small, dense LDL (type B) - tendency towards postprandial lipaemia. (who.int)
Dyslipidemia is a high level of cholesterol and/or triglycerides or a low level of high-density lipoprotein (HDL) cholesterol. (msdmanuals.com)
Using data from the second phase (1991-1994) of the Third National Health and Nutrition Examination Survey (NHANES III), we examined associations between 22 polymorphisms in 13 candidate genes and four serum lipids: high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglycerides (TG). (cdc.gov)
Defining the cholesterol content in these triglyceride-rich lipoproteins is clinically important because this is the substrate for development of the atherosclerotic plaque rather than the triglycerides. (medscape.com)
Therefore, there is delayed conversion of VLDL to LDL, resulting in elevation in TRL-C. Since lipolysis is impaired, LDL particles are also enriched in apoCIII and triglycerides which ultimately transform into smaller and more numerous particles. (medscape.com)
[ 13 ] If triglycerides are lowered by lifestyle changes, fibrates, or omega-3 fatty acids, there is a reduction in TRL-C, apoB, and apoCIII, and this shifts from small dense LDL particles (and hence small dense LDL-C) to larger LDL particles. (medscape.com)

This study aimed to examine the association between NMR-based lipoprotein particle measurements and standard lipids with AVC. (elsevierpure.com)
for the Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) Research Group 2021, ' Lipoprotein particle profiles compared with standard lipids in the association with subclinical aortic valve calcification in apparently healthy Japanese men ', Circulation Journal , vol. 85, no. 7, pp. 1076-1082. (elsevierpure.com)
Plasma lipoproteins are macromolecular complexes of lipids and proteins that are classified by density and electrophoretic mobility. (medscape.com)
To get around this problem, the body packages cholesterol and other lipids into minuscule protein-covered particles that mix easily with blood. (harvard.edu)
Levels of lipoproteins and therefore lipids, particularly low-density lipoprotein (LDL) cholesterol, increase slightly as people age. (msdmanuals.com)
We propose the hypothesis that small high-density lipoprotein (HDL) particles reduce the risk of Alzheimer's disease (AD) by virtue of their capacity to exchange lipids, affecting neuronal membrane composition and vascular and synaptic functions. (cdc.gov)

In a recent article published in the journal Nutrition, researchers in Australia summarized how diet could help decrease low-density lipoprotein cholesterol (LDLc) or triglyceride concentrations in polygenic hypercholesterolemia. (news-medical.net)
4. The only significant correlation between maternal and fetal lipoprotein concentrations was in lipoprotein (a) levels ( r = 0.791, P = 0.002). (portlandpress.com)
The relative concentrations of free cholesterol to phospholipid in maternal and fetal lipoproteins do not indicate the existence of a concentration gradient favouring free cholesterol diffusion across the placenta. (portlandpress.com)
1 Among the traditional cardiovascular risk factors, the lipid profile in RA has often been described as "pro-atherogenic", 2 based on decreased HDL-cholesterol (HDL-C) and increased LDL:HDL-C ratio and lipoprotein (a) plasma concentrations in both active and treated RA. (bmj.com)
Low levels of high-density lipoprotein cholesterol (HDL), or hypoalphalipoproteinemia (HA), includes a variety of conditions, ranging from mild to severe, in which concentrations of alpha lipoproteins or high-density lipoprotein (HDL) are reduced. (medscape.com)
Elevated serum concentrations of small HDL particles in early pregnancy associate with prediabetes and insulin resistance at two years postpartum. (springer.com)
Results from our study contribute to a growing body of literature identifying key determinants of plasma lipoprotein concentrations and could provide insight into the biological mechanisms underlying serum lipid and cholesterol concentrations. (cdc.gov)

Apolipoprotein B100 (apoB100) is a building block of very low-density lipoproteins (VLDLs), intermediate-density lipoproteins (IDLs), and low-density lipoproteins (LDLs). (healthmatters.io)
As it circulates in blood, it picks up apolipoprotein C-II (apoC-II) and additional apoE donated from high-density lipoprotein (HDL). (wikipedia.org)
We also know that the apolipoprotein particle is similar to plasminogen, so it can promote clotting. (medscape.com)
The major apolipoproteins of high-density lipoprotein (HDL) are alpha lipoproteins (ie, apolipoprotein A-I [apo A-I], apo A-II, apo A-IV), which are soluble and can move between different classes of lipoproteins. (medscape.com)
lt;p>The apolipoprotein E (ApoE) gene makes a protein which, when combined with fat, becomes a lipoprotein. (feedburner.com)
Apolipoprotein B (apoB) is a nonexchangeable lipoprotein that exists in two forms in humans, apoB-100 and apoB-48. (medscape.com)
Lipoprotein (a) (Lp[a]) is composed of a low density lipoprotein (LDL) particle with an apolipoprotein B-100 (apo B100) component that is covalently linked via a disulfide bridge to an apolipoprotein (a) molecule, which is highly homologous to plasminogen. (medscape.com)

Israeli profound Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis 1989 soulmate 1 suvs from party began to your person level! (cegolf.info)
The proteins, termed apolipoproteins, play an important role in lipoprotein metabolism. (medscape.com)

Objective This cross-sectional study examined whether contrasting distributions of nuclear magnetic resonance (NMR)-measured lipoproteins contribute to differences in the prevalence of subclinical atherosclerosis measured using coronary artery calcium (CAC) between the two groups of middle-aged males: the US-residing Caucasian (US-White) and Japan-residing Japanese (Japanese). (elsevierpure.com)
The LDL particle can actually promote atherosclerosis. (medscape.com)
Phospholipid transfer protein: its impact on lipoprotein homeostasis and atherosclerosis. (nih.gov)
A low HDL cholesterol level is thought to accelerate the development of atherosclerosis because of impaired reverse cholesterol transport and possibly because of the absence of other protective effects of HDL, such as decreased oxidation of other lipoproteins. (medscape.com)
In fact, a study suggests that ~50% of the cholesterol found in atherosclerotic plaque is derived from TRL-C even though, in most patients, TRL-C levels are much lower than calculated LDL-C. [ 8 ] Another area of confusion is that hypertriglyceridaemia is associated with a myriad of lipoprotein modifications and it is unclear which of these changes (if not all) are causal for atherosclerosis. (medscape.com)

VLDL is one of the five major groups of lipoproteins (chylomicrons, VLDL, intermediate-density lipoprotein, low-density lipoprotein, high-density lipoprotein) that enable fats and cholesterol to move within the water-based solution of the bloodstream. (wikipedia.org)
Fat particles called chylomicrons build up in the blood. (medlineplus.gov)

This test measures the number of particles in each of the 8 LDL subclasses. (healthmatters.io)
Six of these 8 subclasses are small LDL subclass particles. (healthmatters.io)
Influence of adiposity and physical activity on the cardiometabolic association pattern of lipoprotein subclasses to aerobic fitness in prepubertal children. (uib.no)
Cardiometabolic associations between physical activity, adiposity, and lipoprotein subclasses in prepubertal norwegian children. (uib.no)

The main types of lipoproteins that carry cholesterol are low-density lipoproteins (LDL) and high-density lipoproteins (HDL). (forksoverknives.com)

Lipoproteins are substances made of protein and fat that carry cholesterol through your bloodstream. (healthmatters.io)
In the early 2010s both the lipid composition and protein composition of this lipoprotein were characterised in great detail. (wikipedia.org)
Familial lipoprotein lipase deficiency is a group of rare genetic disorders in which a person lacks a protein needed to break down fat molecules. (medlineplus.gov)
Here, we report that in AD patients and two mouse models of AD, overexpression of serum response factor (SRF) and myocardin (MYOCD) in cerebral vascular smooth muscle cells (VSMCs) generates an Aβ non-clearing VSMC phenotype through transactivation of sterol regulatory element binding protein-2, which downregulates low density lipoprotein receptor-related protein-1, a key Aβ clearance receptor. (nature.com)
The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). (nih.gov)
In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. (nih.gov)
Low-density lipoproteins carry cholesterol produced by the liver to the rest of the body, allowing cells to extract the fat and protein content for various uses. (forksoverknives.com)
These tiny particles, called lipoproteins (lipid plus protein), move cholesterol and other fats throughout the body. (harvard.edu)
Our research shows that these toxic protein deposits that form in the brains of people living with Alzheimer's disease most likely leak into the brain from fat-carrying particles in blood, called lipoproteins," he continues. (kfor.com)
While further studies are now needed, this finding shows the abundance of these toxic protein deposits in the blood could potentially be addressed through a person's diet and some drugs that could specifically target lipoprotein amyloid, therefore reducing their risk or slowing the progression of Alzheimer's disease . (kfor.com)
Exercise also enlarges the particles of protein that binds with cholesterol to form lipoproteins like LDL. (healthstatus.com)
When administrating nanoparticles to cells, protein corona has a big impact on the half-life and cellular uptake of the particles. (helsinki.fi)

In conclusion, evolocumab significantly lowers atherogenic lipoprotein particles including low-density and remnant lipoproteins. (johnshopkins.edu)
Even among LDL particles, small dense LDL may be more atherogenic than large LDL. (aruplab.com)

Once in circulation, VLDL will come in contact with lipoprotein lipase (LPL) in the capillary beds in the body (adipose, cardiac, and skeletal muscle). (wikipedia.org)
Familial lipoprotein lipase deficiency is caused by a defective gene that is passed down through families. (medlineplus.gov)
People with this condition lack an enzyme called lipoprotein lipase. (medlineplus.gov)
Risk factors include a family history of lipoprotein lipase deficiency. (medlineplus.gov)
This test looks for lipoprotein lipase activity in your blood. (medlineplus.gov)
Pancreatitis that is related to lipoprotein lipase deficiency responds to treatments for that disorder. (medlineplus.gov)
Contact your provider for screening if someone in your family has lipoprotein lipase deficiency. (medlineplus.gov)

High-density lipoproteins (HDL) comprise particles of different size, density and composition and their vasoprotective functions may differ. (healthmatters.io)
Ye, J 2012, ' Hepatitis C virus: A new class of virus associated with particles derived from very low-density lipoproteins ', Arteriosclerosis, thrombosis, and vascular biology , vol. 32, no. 5, pp. 1099-1103. (elsevierpure.com)
Human plasma samples were treated with Sudan Black B to stain the lipid component in lipoproteins, then the stained lipoproteins were separated by frit inlet asymmetrical flow field-flow fractionation (FI-AFlFFF), according to the lipoprotein particle sizes, with the selective detection of eluting lipoprotein fractions, high-density lipoproteins (HDL), low-density lipoproteins (LDL) and very-low-density lipoproteins (VLDL), at 610 nm. (elsevierpure.com)
LCAT is an enzyme bound to HDLs and low-density lipoproteins (LDLs) in the plasma. (medscape.com)
Arterial inflammation that precedes development of the atherosclerotic plaque is caused by accumulation of LDL (low density lipoproteins) in the extracellular matrix of the blood vessels. (europa.eu)
If LDL are cholesterol delivery trucks, high-density lipoproteins are the garbage trucks. (forksoverknives.com)
The 2 most commonly known lipoproteins are low-density lipoproteins (LDL) and high-density lipoproteins (HDL). (uhhospitals.org)
Lipoprotein particles are classified according to their density into high-density lipoproteins (HDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and very low-density lipoproteins (VLDL). (labtestsonline.org.uk)
most is in the very low-density lipoproteins (VLDL). (labtestsonline.org.uk)
As the body's cells extract fatty acids from VLDLs, the particles turn into intermediate density lipoproteins, and, with further extraction, into LDL particles. (harvard.edu)
Some are removed rapidly by the liver, and some are changed into low-density lipoproteins. (harvard.edu)

Very-low-density lipoprotein (VLDL), density relative to extracellular water, is a type of lipoprotein made by the liver. (wikipedia.org)
Circulating in blood, extracellular vesicles (EVs) and lipoprotein particles (LPs) have diagnostic and prognostic value. (nist.gov)
Extracellular vesicles (EVs) are lipid bilayer-enclosed nano-sized particles that are found in all body fluids. (helsinki.fi)

VLDL is converted in the bloodstream to low-density lipoprotein (LDL) and intermediate-density lipoprotein (IDL). (wikipedia.org)
Cholesterol and other fats are carried in your bloodstream as spherical particles called lipoproteins. (uhhospitals.org)
lt;br />The lipoprotein ApoE is a very low-density lipoprotein, responsible in part for removing cholesterol from the bloodstream. (feedburner.com)

Intermediate-density lipoprotein (IDL) particles form as VLDLs give up their fatty acids. (harvard.edu)
AF4 fractionation revealed that CS-6253 treatment displaced apoE from HDL to intermediate-density- and low density-lipoprotein (IDL/LDL)-sized particles in plasma. (cdc.gov)

Large VLDL particles, also known as very-low-density lipoprotein particles, play a significant role in lipid metabolism and cardiovascular health. (healthmatters.io)
The purpose of this study was to investigate the effects of the ABCA1 agonist peptide CS-6253 on amyloid- peptides (A) and lipoproteins in plasma and cerebrospinal fluid (CSF) of cynomolgus monkeys, a species with amyloid and lipoprotein metabolism similar to humans. (cdc.gov)

These are spherical particles which have an exterior composed mainly of water-soluble proteins. (home-remedies-for-you.com)

To evaluate the effect of evolocumab on serum levels and size of lipoprotein particles, we conducted a post hoc subanalysis of 619 patients from the Durable Effect of PCSK9 Antibody Compared with Placebo Study or DESCARTES trial, a 52-week, randomized, double-blind, placebo-controlled, global study of patients with hyperlipidemia. (johnshopkins.edu)
Whereas treatment of E-LDL particles with human serum albumin reduced their free fatty acid content, both cholesterol and free fatty acids were decreased by methyl-beta cyclodextrin, both treatments resulting in a dose-dependent inhibition of the C1-activating ability of the particles. (europa.eu)
The firm presented a demonstration of this technology in a paper published last month in Clinica Chimica Acta , in which researchers including Madasamy used the platform to identify serum proteins involved in the process of plaque particle formation linked to Alzheimer's. (genomeweb.com)
These constituents are incubated with serum from test subjects, which leads to the formation of insoluble plaque particles as the plaque-forming constituents work as substrates for the plaque-related serum components. (genomeweb.com)
In the Clinica Chimica Acta paper, the researchers found via their flow cytometry analysis that roughly 35 percent of AD serum samples produced significantly higher levels of cholesterol particle formation than age-matched controls. (genomeweb.com)
The study also found, however, that 15 percent of the control serum samples also demonstrated Aβ42 particle formation when run on the plaque array. (genomeweb.com)
The antigen is prepared from a modified Venereal Disease Research Laboratory (VDRL) antigen suspension containing choline chloride to eliminate the need to heat-inactivate serum, ethylene-diamine-tetra-acetic acid (EDTA) to enhance the stability of the suspension, and finely divided charcoal particles as a visualizing agent. (cdc.gov)

Research studies have demonstrated that individuals with a high number of small low-density lipoprotein (LDL) particles have a greater cardiovascular disease (CVD) risk than those with fewer but larger LDL particles for a given total cholesterol concentration. (aruplab.com)

Conclusions Variations in the distribution of NMR-measured lipoprotein particles partially accounted for the difference in the CAC-prevalence between middle-aged US-White and Japanese men. (elsevierpure.com)

We studied the association of lipoproteins measured by proton nuclear magnetic resonance spectroscopy with carotid intima-media thickness (IMT) in apparently healthy individuals (N = 5538, 38% White, 28% African American, 22% Hispanic, 12% Chinese). (nih.gov)

Clearance of lipoprotein remnant particles in adipose tissue and muscle in humans. (ox.ac.uk)

SMART was a trial of intermittent use of ART (drug conservation [DC]) versus continuous of ART (viral suppression [VS]). Methods: In a nested case-control study, lipoprotein particles (p) by nuclear magnetic resonance were measured at baseline and at the visit prior to the CVD event (latest levels) for 248 patients who had a CVD event and for 480 matched controls. (umn.edu)
Methods In a population-based study of 570 randomly selected asymptomatic men aged 40-49 years (270 US-White and 300 Japanese), we examined the relationship between race/ethnicity, NMR-measured lipoproteins and CAC (measured by Electron Beam CT and quantified using the Agatston method) using multivariable robust Poisson regression adjusting for traditional and novel risk factors for coronary heart disease (CHD). (elsevierpure.com)

An analytical method to improve the characterization of lipoprotein fractions is presented. (elsevierpure.com)
3. Pregnant women had raised levels of all lipid and lipoprotein fractions compared with control subjects. (portlandpress.com)

How are lipoprotein particle number and size related to cardiovascular events? (aruplab.com)
AIMS: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a promising new target for reducing low-density lipoprotein cholesterol (LDL-C) and cardiovascular events in high-risk patients. (bvsalud.org)

HDLs comprise a family of heterogeneous particles that vary by size, density, composition, and functionality. (healthmatters.io)
We hypothesised that prolonged telerehabilitation could also improve proinflammatory status and lipoprotein particle composition. (biosferteslab.com)
The potential for free cholesterol diffusion between mother and fetus and rates of cholesterol esterification and transfer between lipoproteins were determined and related to the differences in composition between fetal and maternal lipoproteins. (portlandpress.com)
5. There was no umbilical arteriovenous differences in lipoprotein concentration or composition. (portlandpress.com)

Previous studies showing that smaller low-density lipoprotein (LDL) size is associated with greater atherosclerotic risk did not adequately control for small and large LDL particle correlation. (nih.gov)
Low-density lipoprotein (LDL) particles cause atherosclerotic cardiovascular disease (ASCVD) through their retention, modification, and accumulation within the arterial intima. (oulu.fi)

LDL patterns A and B refer to the size of LDL cholesterol particles in the blood. (healthmatters.io)
Particles in your blood called lipoproteins carry cholesterol to your body's cells that need it. (webmd.com)
It is transported by the lipoproteins, which act as carriers in blood. (home-remedies-for-you.com)
Low-density lipoprotein (LDL) or 'bad cholesterol' is the major cholesterol carrier in the blood. (home-remedies-for-you.com)
Low-density lipoprotein cholesterol (LDL-C) is a calculated estimate of the cholesterol that is deposited in blood vessel walls. (labtestsonline.org.uk)
Researchers from Curtin University report that a "probable" cause of Alzheimer's disease is the leaking of fat-carrying particles transporting toxic proteins into the brain from blood. (kfor.com)
This 'blood-to-brain pathway' is significant because if we can manage the levels in blood of lipoprotein-amyloid and prevent their leakage into the brain, this opens up potential new treatments to prevent Alzheimer's disease and slow memory loss. (kfor.com)
In this study, they tested the blood-to-brain pathway hypothesis by genetically engineering mice capable of producing human amyloid-only livers that create lipoproteins. (kfor.com)
Amyload is based on the early detection and quantitation of Aβ42 and tau particles in the blood that signal the formation in the brain of the amyloid plaques thought to be responsible for Alzheimer's disease. (genomeweb.com)
Small LDL particles are more dangerous than the big ones as they can hide in tight spaces like heart lining and small blood vessels, build cholesterol plaque and cause blockage, leading to heart attack. (healthstatus.com)
The genetic basis for elevation in lipid levels is not well understood, but substantial heritability has been demonstrated in twin [ 9 ] and family-based [ 10 - 12 ] studies, which have estimated that approximately 43% to 83% of the variance in blood lipid and lipoprotein levels is attributable to genetic factors. (cdc.gov)

In earlier research, the Curtin team found that beta-amyloid forms outside the brain from lipoproteins. (kfor.com)
As we predicted, the study found that mouse models producing lipoprotein-amyloid in the liver suffered inflammation in the brain , accelerated brain cell death and memory loss," Prof. Mamo explains. (kfor.com)
For instance, in the case of the Alzheimer's test, the array is designed to capture plaque particles including amyloid-β 42, tau, cholesterol, and α-synuclein. (genomeweb.com)

Low-density lipoprotein (LDL) cholesterol transports cholesterol particles throughout your body. (indiatimes.com)

The virus then infects more hepatocytes by entering the cells through the low-density lipoprotein receptor, which mediates uptake of majorities of VLDL-derived lipoprotein particles. (elsevierpure.com)

By analysis of the TRL subfractions, the RP removal was likely to be confined to the largest chylomicron remnant particles. (ox.ac.uk)
[ 6 ] The confusion arises as to what to call this "other" cholesterol (non-HDL-C minus LDL-C). The most accurate term is triglyceride-rich lipoprotein cholesterol (TRL-C) but it has also been called 'remnant cholesterol' [ 7 ] and most commonly VLDL-C. (medscape.com)

The capability of this technique has been evaluated with plasma samples obtained from patients with coronary artery disease (CAD), and it showed that the retention profile of patients' lipoprotein samples was clearly distinct from those of healthy persons. (elsevierpure.com)
First, EVs and lipoprotein particles were removed from fresh frozen plasma by membrane filtration. (helsinki.fi)
Activation of phosphatidic acid phosphatase promotes hepatic triglyceride synthesis, induces secretion of triglyceride-rich, very low-density lipoprotein particles, and consequently, increases plasma triglyceride levels. (medscape.com)
The integration of quantitative lipid and lipoprotein profiling of human plasma may provide a powerful approach to inform early disease diagnosis and prevention. (cdc.gov)
RESULTS: Following CS-6253 intravenous injection, within minutes, small plasma high-density lipoprotein (HDL) particles were increased. (cdc.gov)

An average size of LDL peak subclass particles measuring less than 218 angstroms, as measured with Ion Mobility, is associated with a 1.35-fold increased risk for CVD. (healthmatters.io)
We introduce a method, single-particle profiler, that provides single-particle information on the content and biophysical properties of thousands of particles in the size range 5-200 nm. (scilifelab.se)
Nanoparticles or nanomaterials are increasingly important due to their unique physical and chemical properties, such as particle size, zeta potential, and molecular weight. (news-medical.net)
The potential of this technique comes with the direct injection of a stained lipoprotein sample without a prior procedure such as ultracentrifugation for sample preparation, and the size calculation of lipoprotein particles from the experimental retention time by theory. (elsevierpure.com)
High-resolution nuclear magnetic resonance (NMR) technology is used to measure a patient's lipoprotein particle number and size. (aruplab.com)
In the Paediatric Diabetes Unit at Tygerberg Hospital (TBH) correlated, while HDL particle size was negatively correlated, the practice has been to monitor fasting lipid profiles annual y in to HbA1c levels. (who.int)
100 nm) are ubiquitous in ambient urban and indoor air from multiple sources and may contribute to adverse respiratory and cardiovascular effects of particulate matter (PM). Depending on their particle size, inhaled UFP are efficiently deposited in nasal, tracheobronchial, and alveolar regions due to diffusion. (cdc.gov)

The cholesterol content in these triglyceride-rich lipoproteins has been estimated by the Freidwald formula as approximately triglyceride levels divided by five, because these lipoproteins have ~60% triglyceride and 12% cholesterol (a 5:1 ratio). (medscape.com)

Conclusions: Lipoprotein particles, especially lower levels of small and large HDL-p identify HIV-infected patients at increased risk of CVD independent of other CVD risk factors. (umn.edu)
Lipoprotein (a) levels were significantly greater in the pregnant women [112(12.2) mg/l] than in the control women [50 (10.0) mg/l]. (portlandpress.com)
0.0001), but high-density lipoprotein levels were similar. (portlandpress.com)
The increase in levels of lipoproteins that occurs with age can result in dyslipidemia. (msdmanuals.com)
Previous reports from the Framingham Heart Study suggested a strong positive relationship between coronary heart disease and elevated levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels, in addition to an inverse relationship between the disease and high-density lipoprotein cholesterol (HDL-C) levels [ 5 - 8 ]. (cdc.gov)

are particles of proteins and other substances. (msdmanuals.com)

Advanced lipoprotein characterization was performed using the NMR-based Liposcale test. (biosferteslab.com)

abstract = "The level of low-density lipoprotein cholesterol (LDL-C) reflects the cholesterol carried mainly by low-density lipoprotein particles (LDL-P). LDL-C, however, does not always correlate with LDL-P because of the variable amounts of cholesterol per particle. (johnshopkins.edu)
abstract = "Objective: To study the association of lipoprotein particles with CVD in a subgroup of HIV-infected patients who were enrolled in the Strategies for Management of Anti-Retroviral Therapy (SMART) study. (umn.edu)

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus. (planteome.org)
300 mg/dL or those who have type 3 hyperlipoproteinemia owing to an increased secretion of triglyceride-rich particles, which can produce marked hypertriglyceridemia in some cases. (medscape.com)

Results The US-White compared with the Japanese had significantly different NMR-measured lipoprotein particle distributions. (elsevierpure.com)

They likewise found a correlation of 87 percent between brain imaging data and Aβ42 particle formation in mild cognitive impairment, severe Alzheimer's patients, and age-matched controls. (genomeweb.com)

Lipoprotein particles were measured using NMR spectroscopy. (elsevierpure.com)
Method The sex-stratified association of 791 metabolites detected by liquid chromatography-mass spectrometry (LC-MS) and 91 lipoprotein particles measured by nuclear magnetic spectroscopy (NMR) with WHRadjfatmass and fat mass were assessed using three population-based cohorts: EpiHealth (n = 2350) as discovery cohort, with PIVUS (n = 603) and POEM (n = 502) as replication cohorts. (lu.se)

[ 1 ] LpX, an abnormal multivesicular-like lipoprotein that accumulates in patients with FLD, contributes to renal disease. (medscape.com)
HDL is considered a protective lipoprotein because it contributes to reverse cholesterol transport. (who.int)

Small LDL subclass particles cause plaque buildup to progress much faster because they enter the artery wall more easily than large LDL particles. (healthmatters.io)
The array's plaque-forming constituents are chosen to allow for isolation of the plaque particles of interest to the disease under investigation. (genomeweb.com)
These particles are then passed on to a flow cytometer where they are separated and quantified by plaque type. (genomeweb.com)

High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler. (scilifelab.se)

Lecithin-cholesterol acyltransferase (LCAT) is a lipoprotein-associated enzyme which plays a large role in the esterification of free cholesterol, the maturation of high density-lipoprotein (HDL) particles, and the intravascular stage of reverse cholesterol transport (RCT). (medscape.com)
In addition to trypsin, plasmin, thrombin, tryptase and matrix metalloprotease-2 each yielded E-LDL particles with high C1-activating efficiency, and the C1 activation extent was strictly dependent on cholesterol esterase treatment in all cases. (europa.eu)
High-density lipoprotein (HDL) cholesterol, on the other hand, picks up excess cholesterol and takes it back to your liver. (indiatimes.com)
What is HDL (high-density lipoprotein) cholesterol? (uhhospitals.org)
High-density lipoprotein (HDL) particles are called "good" cholesterol because some of them remove cholesterol from circulation and from artery walls and return it to the liver for excretion. (harvard.edu)
Atheroload is intended for the detection of abnormal low- and high-density lipoprotein cholesterol particle formation. (genomeweb.com)
Another study found that extensive exercise increases the production of " Ëœgood" â„¢ cholesterol, or HDL (high density lipoprotein). (healthstatus.com)
12] Screening should commence at 2 years trial, small very low-density lipoprotein (VLDL), small high- of age if there is a family history of hypercholesterolaemia, early density lipoprotein (HDL), medium low-density lipoprotein (LDL) cardiovascular disease or if the family history is unknown. (who.int)

Fourteen of those were associated in both sexes and belonged to very-large or large HDL particles, all being inversely associated with both WHRadjfatmass and fat mass. (lu.se)
Conclusion Two sphingomyelins were inversely linked to body fat distribution in both men and women without being associated with fat mass, while very-large and large HDL particles were inversely associated with both fat distribution and fat mass. (lu.se)

For these short fibers, which can be fully engulfed by lung cells and do not dissolve in airway fluids in less than a few weeks, their clearance will be similar to other mineral and vitreous particles. (cdc.gov)
In the setting of increased hepatic lipogenesis (Take Home Figure), the liver secretes enlarged VLDL which is enriched but results in delayed peripheral lipolysis and clearance of these triglyceride-rich particles. (medscape.com)

We use our single-particle profiler to measure the messenger RNA encapsulation efficiency of lipid nanoparticles, the viral binding efficiencies of different nanobodies, and the biophysical heterogeneity of liposomes, lipoproteins, exosomes and viruses. (scilifelab.se)

Anatomy19

Organisms12

Diseases25

Chemicals and Drugs125

Analytical, Diagnostic and Therapeutic Techniques and Equipment33

Psychiatry and Psychology1

Phenomena and Processes46

Technology, Industry, Agriculture9

Information Science3

Health Care4

Triglycerides14

Lipids6

Concentrations7

Apolipoprotein7

Apolipoproteins2

Atherosclerosis5

Chylomicrons2

Subclasses4

Types of lipoproteins1

Protein12

Atherogenic2

Lipase7

Density lipoproteins11

Extracellular3

Bloodstream3

Intermediate-density2

Metabolism2

Spherical particles1

Serum7

Larger LDL particles1

Middle Aged1

Nuclear magnetic res1

Humans1

Methods2

Fractions2

Cardiovascular events2

Composition4

Atherosclerotic2

Blood11

Amyloid3

Cholesterol particles1

Uptake1

Remnant2

Plasma5

Size7

Triglyceride levels1

Levels5

Substances1

Characterization1

Abstract2

Secretion2

Significantly1

Alzheimer's1

Spectroscopy2

Contributes2

Plaque3

Nano-sized1

High8

Inversely2

Clearance2

Viruses1