Particles bone matrix. Medical search. Frequent questions

Extracellular vesicles (EVs) are lipid bilayer-delimited particles that are naturally released from almost all types of cells but, unlike a cell, cannot replicate. (wikipedia.org)
We know that cancer cells behave like seeds that need the right soil to grow, and we're very interested in how the extracellular matrix, which is basically the material in between cells that holds everything together, affects tumor growth," Fischbach said. (provaeducation.com)
Human osteoblasts Saos-2 were seeded on scaffolds and cellular adhesion, proliferation, differentiation and deposition of bone-like extracellular matrix were evaluated. (manchester.ac.uk)
All tested scaffolds (PCL, PCL/hydroxyapatite and PCL/BaTiO3) supported cell growth and viability, preserving the characteristic cellular osteoblastic phenotype morphology, with PCL/BaTiO3 composite scaffolds exhibiting higher mineralisation (ALP activity) and deposited bone-like extracellular matrix (osteocalcin and collagen I). (manchester.ac.uk)
Functional classification of the most highly expressed transcripts were analyzed, and the pathway analysis indicated that ossification, bone remodeling, and cartilage development were uniquely enriched in the PC whereas both the PC and RZ showed pathway enrichment for skeletal development, extracellular matrix structural constituent, proteinaceous extracellular matrix, collagen, extracellular matrix, and extracellular matrix part pathways . (heightquest.com)
8 nm).Ppy NPs effectively augment the conductivity, surface roughness, andthickness of BC composites despite reducing scaffolds' transparency.BC-Ppy composites were flexible (up to 10 mM Ppy), maintained theirintricate 3D extracellular matrix-like mesh structure in all Ppy concentrationstested, and displayed electrical conductivities in the range of nativecardiac tissue. (ibecbarcelona.eu)
Articular cartilage is composed of extracellular matrix (water, collagen, proteoglycans and calcium salt) and chondrocytes. (changepain.ch)
In this bone scaffold material, it is necessary to form collagen fibers which are the extracellular matrix of particles derived from Montipora digitata skeleton capillary vessels and newly formed bone. (jarde.jp)
A phantom construct system has been used to optimize the measurement conditions in which agar hydrogel with concentration from 0, 0.75 to 2% with/without hydroxyappatite particles have been injected to 3D porous poly (lactic acid) scaffolds to simulate the collagenous extracellular matrix (ECM) and mineralized ECM. (dundee.ac.uk)
Osteoblasts are specialized cells that reside in the bone surface and are responsible for the synthesis of the bone extracellular matrix and influence bone mineralization while osteoclasts are responsible for bone resorption 32 . (bvsalud.org)

A composite scaffold of MSC affinity peptide-modified demineralized bone matrix particles and chitosan hydrogel for cartilage regeneration. (bvsalud.org)
Until an ideal bone-grafting material is developed, the regeneration of bone will remain a major focus of periodontal research. (allenpress.com)
Autologous dentin grafts derived from extracted teeth have shown promise as bone graft materials to promote bone regeneration. (bedentalexpert.com)
This study aimed to evaluate the clinical, radiographic and histological results of the use of autologous dentin matrices in various bone regeneration procedures. (bedentalexpert.com)
Several types of nanobiomaterials exist including the manufacturing of nanofibres and nanocomposites to act as scaffolds for cartilage and bone regeneration. (openorthopaedicsjournal.com)
Electrospun nanocomposite for bone tissues regeneration via osteoconduction, osteoinduction, and osteogenesis. (dokumen.pub)
She was awarded with a postdoc fellow from the Ministry of Science at the Technical University of Catalonia in Biomaterials for bone tissue regeneration and since 2010 has been professor at this university. (ibecbarcelona.eu)

The nanotubular TiO 2 surface layers play an important role in the improvement of osseointegration through the enhancement of bone cell adhesion, differentiation, ALP activity, bone matrix deposition, apatite deposition rates [ 15 ], and hemocompatibility of Ti and Ti-based materials [ 16 - 18 ]. (hindawi.com)
Contact osteogenesis is characterized by deposition of a newly formed bone in direct contact with the implant surface. (bvsalud.org)
Workplace ultrafine particle respiratory deposition measurement. (cdc.gov)

Holtzclaw D. Extraction site preservation using new graft material that combines mineralized and demineralized allograft bone: a case series report with histology. (nobelbiocare.com)
The demineralization of graft allows for immediate access to the growth factors (BMPs) inherent in allograft bone when it is placed into the surgery site. (vtsonline.com)
ViBone Moldable combines Aziyo's expertise in viable cellular allograft bone matrix processing with handling enhancements for a better operating room experience," said Terry Rich, President and Chief Executive Officer of Surgalign Holdings. (surgalign.com)

Meanwhile, the DBM-E7/CS scaffold increased matrix production and improved chondrogenic differentiation ability of BMMSCs in vitro . (bvsalud.org)

A porous structured bone with particle size range from 0.25 mm to 1 mm and available volume of 0.25 cc to 2.0 cc. (nobelbiocare.com)
Montipora digitata exoskeleton-derived aragonite particles are porous, bioresorbable bone scaffold and applied to bone defects as natural materials. (jarde.jp)

It contains cancellous bone particles as well as demineralized cortical bone particles and fibers, delivering the necessary components for bone formation (osteoinduction, osteoconduction and osteogenesis) along with excellent handling and cohesive properties. (surgalign.com)

In this study, we constructed a composite scaffold combining mesenchymal stem cells (MSCs) E7 affinity peptide -modified demineralized bone matrix (DBM) particles and chitosan (CS) hydrogel for cartilage engineering . (bvsalud.org)
Cell proliferation and DNA content analysis indicated that the DBM-E7/CS scaffold promoted better rat bone marrow -derived MSCs (BMMSCs) survival than the CS or DBM/CS groups. (bvsalud.org)
This image shows a bone scaffold seeded with tumor cells. (provaeducation.com)
Achieve faster and stronger bone healing compared with using bone substitutes, because it provides both an osteoconductive scaffold and also osteoinductive growth factors (BMPs). (vtsonline.com)
Bone will heal faster when voids are filled with bone graft, because it provides osteoconductive scaffold for host bone to grow on and native, osteoinductive BMPs that attract osteoblasts to the site. (vtsonline.com)
In regenerative dental therapy, the development of bone scaffold materials to enable augmentation of bone for dental implant and prosthesis treatment is important. (jarde.jp)

OBJECTIVE: Compared to autologous bone grafts, allogeneic bone grafts integrate slowly, which can adversely affect clinical outcomes. (jefferson.edu)

Osseous healing using injectable calcium sulfate-based putty for the delivery of demineralized bone matrix and cancellous bone chips. (rush.edu)
It consists of osteoinductive Demineralized Bone Matrix (DBM) and osteoconductive cancellous bone chips. (vtsonline.com)

The creos allografts portfolio offers you a wide range of particulate grafts, a 100% demineralized bone matrix (dbm) putty and a pericardium barrier membrane. (nobelbiocare.com)
Federal regulators are warning about a potential tuberculosis risk from bone matrix grafts, following a recent outbreak linked to products by Aziyo Biologics, which has resulted in at least two deaths. (aboutlawsuits.com)

Gold particles indicating type I collagen appeared on the bone matrix, and they were also detected in the vacuoles and vesicles in the E-64-treated osteoclasts. (elsevierpure.com)

The test group of 7 subjects received corticocancellous particulate allograft (Mineross) mixed with autogenous bone chips (70:30) harvested using a bone scraper (SafeScraper TWIST). (papadakis.org)
The autogenous bone chips did not provide any additional benefit when compared with allograft alone that had lot verified osteoinductive activity. (papadakis.org)
The use of autogenous bone chips for oral and maxillofacial bone augmentation procedures is widespread in clinical practice. (karaventures.com)

Functional β-tricalcium phosphate (β-TCP) scaffolds modified by DPIYALSWSGMA (DPI) peptide, a bone marrow-derived mesenchymal stem cell (BMSC) affinity peptide, were constructed using an adsorption/freeze-drying strategy. (biomedcentral.com)
The single-step multi-material additive manufacturing technology used for the fabrication of electroactive PCL/BaTiO3 composite scaffolds holds great promise for sustainability (reduced material waste and manufacturing costs) and it importantly suggests PCL/BaTiO3 scaffolds as promising candidates for load bearing bone tissue engineering applications to solve unmet clinical needs. (manchester.ac.uk)
The MG63 bone cells seeded in the scaffolds and cultured for 4 weeks have been monitored by the established protocol exhibiting the increased mechanical strength in the pore wall where the ECM or mineralized ECM was assumed to be formed in comparison to empty pores. (dundee.ac.uk)

The inclusion of BaTiO3 ceramic particles (10% wt. (manchester.ac.uk)
Class I IBS, taking advantage of ceramic particles or granules as the support for bone formation, are already commercialized and widely employed in clinics. (mad4am.fr)

Contact of wear particles with body fluids can result in widespread dissemination of extractable constituents from joint implants. (orthoclinic-hamburg.de)
The aim of this in vitro study is to clarify whether there is a mutagenic and/or carcinogenic risk from CoCrMo and Ti6Al wear particles. (orthoclinic-hamburg.de)
To obtain the greatest possible elution of all constituents the metallic wear particles were extracted with dimethylsulfoxyd and water and the resulting eluates mixed together. (orthoclinic-hamburg.de)
Wear results when surfaces produce local mechanical damage and unwanted loss of material and the resultant generation of wear particles. (medscape.com)
Willert found that capsular tissue has some capacity to transport wear particles through the lymphatic system by way of perivascular lymph spaces. (medscape.com)
The number of foreign body inflammatory cells (macrophages and giant cells) present correlates with the number of polyethylene wear particles. (medscape.com)
Wear particles produce a series of responses on both cellular and tissue levels. (medscape.com)

During physiological mineralization, bone mineral particles are deposited in and around collagen type I fibers. (provaeducation.com)
Therefore, we cultured fibroblast cells and added the particles in order to investigate the effect of cell proliferation ability and production of collagen fibers. (jarde.jp)

Achieves faster and stronger bone healing than bone substitutes due to osteoinductive growth factors (BMPs) inherent in natural bone. (vtsonline.com)
Injectable bone substitutes (IBS) represent compelling options for bone regenerative medicine as they can be used to optimally fill a complex bone defect through minimally invasive intervention. (mad4am.fr)

The exceptional regenerative capabilities of bone make it one of the most transplanted of human tissues. (allenpress.com)
In contrast, Class II IBS, where cements serve as a stiff matrix for the development of mineralized tissues, associated with polymers, are still in their early stages but have shown significant improvements versus Class I products. (mad4am.fr)
[ 15 ] If this system is overwhelmed, then these particles accumulate in periarticular tissues and are subsequently phagocytosed by macrophages in the pseudocapsule. (medscape.com)
Finally, the effective joint space can also expand into soft tissues as well as bone. (medscape.com)
The dermis offers low resistance, as do almost all internal tissues except bone, which is a poor conductor of electricity. (medscape.com)

Although autogenous bone is considered the ideal regenerative material for these defects, patients may not tolerate an operating room procedure to harvest large amounts of bone from the iliac crest or ribs. (allenpress.com)

Electrospun biomaterials for bone tissue engineering. (dokumen.pub)

Bones mostly consist of composite materials based on almost equivalent volume fractions of mineral (apatite) and organic (collagen) components. (sorbonne-universite.fr)
In this letter, we show by theory and experiment that the variability of the strong phosphate bands in the ATR-FTIR spectra of a series of modern and archeological bone samples can be related to electrostatic interactions affecting apatite particles and depending on the bone collagen content. (sorbonne-universite.fr)

Now, an interdisciplinary Cornell team has identified a new mechanism regulating tumor growth in the skeleton, the primary site of breast cancer metastasis: mineralization of the bone matrix, a fibrous mesh of organic and inorganic components that determines the unique biochemical and biomechanical properties of our skeleton. (provaeducation.com)
The team's paper, " Bone-Matrix Mineralization Dampens Integrin-Mediated Mechanosignalling and Metastatic Progression in Breast Cancer ," published Aug. 7 in Nature Biomedical Engineering. (provaeducation.com)
However, no one had been able to isolate which specific role bone-matrix mineralization plays in this process. (provaeducation.com)
The researchers were able to create such systems by combining organic and inorganic matrix components, including collagen and the bone mineral hydroxyapatite, in a manner that mimicked physiological and pathologic mineralization. (provaeducation.com)
Now we're broadly interested in how other cell types are influenced by varied bone-matrix mineralization. (provaeducation.com)

This paper reclaims the term "mechanotherapy" and presents the current scientific knowledge underpinning how load may be used therapeutically to stimulate tissue repair and remodelling in tendon, muscle, cartilage and bone. (bmj.com)
1 - 4 But what happens at the tissue level to promote repair and remodelling of tendon, muscle, articular cartilage and bone? (bmj.com)

The above findings thus suggest that bone resorption is inhibited by this incomplete degradation of collagen. (elsevierpure.com)

Restoration of large bone defects using a hard-setting, injectable putty containing demineralized bone particles compared to cancellous autograft bone. (rush.edu)
Eliminates morbidity risks associated with the collection of bone autograft. (vtsonline.com)

Many patients present with intrabony defects that could benefit from bone grafting. (allenpress.com)
Demineralized freeze-dried bone (DFDB) allografts have been used in dentistry for more than decades and are the most widely used allografts in treating intrabony defects. (allenpress.com)

Osteoallograft ® is the tried and true solution for natural bone healing and the BENCHMARK against which the performance of all other bone graft materials is measured. (vtsonline.com)

This study basically shows for the first time that physiological interactions between mineral particles and collagen may be able to inhibit the activation of tumor cells that have spread to bone," Fischbach said. (provaeducation.com)
In this way, bone is resorbed and replaced in a physiological process characterized as bone remodeling 39 . (bvsalud.org)

1 It is characterised by the breakdown of articular cartilage, alterations in subchondral bone (including formation of osteophytes), inflammation within the synovium and synovial fluid, and deterioration of the ligaments and muscles in the affected joint. (changepain.ch)

This peri-implant bone formation can be divided in contact and distant osteogenesis. (bvsalud.org)
Regarding to distant osteogenesis, bone tissue is deposited on the surface of old bone in the peri-implant site and the bone surface provided a population of osteogenic cells. (bvsalud.org)

Clinical manifestations of attachment loss and coincident alveolar bone loss associated with periodontitis necessitate therapeutic intervention by a dental care provider. (allenpress.com)
Objectives: The primary aim of the present article was to review the effect and the clinical significance of abutment dis- and reconnection on the peri-implant marginal bone levels. (papadakis.org)
However, the clinical significance of the marginal bone level changes is still inconclusive. (papadakis.org)
Purpose: The primary aim of this randomized, controlled, blinded, clinical trial was to compare a mix of particulate allograft and harvested autogenous particles (Autogenous) to an osteoinductive demineralized bone matrix (DBM) allograft on clinical and histologic outcomes for horizontal ridge augmentation procedure. (papadakis.org)

9 Loss of cartilage precedes a number of cellular changes and the altered biomechanics lead to secondary changes, which include bone remodelling, osteophyte formation, lesions, meniscal tears and extrusion, as well as changes in the synovium, joint capsule, ligaments and periarticular muscles. (changepain.ch)

The average size of the demineralized bone particles from the 100% DFDB group was significantly smaller than that of the other 2 groups containing DFDB. (allenpress.com)
Graft particle size may have an effect on bone fill. (allenpress.com)
Very small, finely divided solids (particles that do not dissolve) that remain dispersed in a liquid for a long time due to their small size (usually less than 1 mm) and electrical charge. (wordinfo.info)
Radiesse is a calcium-based filler material that is essentially calcium hydroxyapatite which is the same chemical composition of bone in a micronized size and then this is placed within a gel matrix so that it can be injected through a needle. (myquintessa.com)

Considering that success of dental implants is not only related to osseointegration, but also with their survival rates, the aim of this study was to perform a literature review about bone remodeling around osseointegrated implants. (elsevier.es)
Therefore, after osseointegration, the initially formed bone, which presents characteristics of spongy bone, is gradually resorbed and replaced by compact bone after 90 days. (elsevier.es)
Among the rare studies found in the literature about bone remodeling after osseointegration, there were no verified studies on the possible influence of implant surface treatments on bone remodeling that occurs after osseointegration. (elsevier.es)
However, the success of this treatment is associated to osseointegration, which is defined as a direct connection between living bone and the surface of implant without interposed soft tissue. (bvsalud.org)
Considering that surface topography, implant design and surface seem to influence the bone apposition, numerous studies demonstrated that the surface roughness of titanium implants affects the rate of osseointegration 16,22,37,43 . (bvsalud.org)

Similar to ViBone, ViBone Moldable is a next-generation viable cell bone matrix processed using a proprietary method optimized to protect and preserve the health of native bone cells to potentially enhance new bone formation. (surgalign.com)
We are confident that ViBone Moldable will be a great addition to the Surgalign portfolio of viable bone matrices addressing this significant market need. (surgalign.com)
In July, Aziyo Biologics issued a bone matrix recall impacting all of its viable products, after a single lot shipped to seven states was linked to cases of tuberculosis. (aboutlawsuits.com)

The 3D culture supernatants were tested for the presence of pro-angiogenic growth factors, TGFβ1, GADPH, bone alkaline phosphatase, osteocalcin, osteonectin, osteopontin, bone sialoprotein and collagen type I. Histology after culture revealed bone chips in a matrix of fibrin remnants and a fibrous-appearing matter. (karaventures.com)
The transcripts for osteocalcin, bone sialoprotein and collagen type I were revealed only via PCR. (karaventures.com)

Periprosthetic bone loss may also occur as a result of an inflammatory reaction due to particulate wear debris as generated in the various wear modes (see Presentation , Modes of Wear). (medscape.com)

Conclusion: Within the limitations of the present review, it can be suggested that minimizing the number of abutment dis- and reconnections would be beneficial to ensure minimal disruption to the peri-implant tissue and marginal bone level. (papadakis.org)

Micro-computed tomographic imaging, and molecular/cellular analyses were used to follow the bone graft over time. (jefferson.edu)
Co-authors Matthew Paszek , associate professor in the Smith School of Chemical and Biomolecular Engineering, and Olivier Elemento , director of the Englander Institute for Precision Medicine and a professor of physiology and biophysics and of computational genomics in computational biomedicine at Weill Cornell Medicine, helped elucidate how bone matrix regulates cellular mechanosignaling, and connect the potential molecular mechanisms to patient data. (provaeducation.com)

The purpose of this study was to evaluate how human DFDB suspended in a polyol matrix affects new bone formation in the rat calvarium critical-sized defect (CSD) model. (allenpress.com)
The 47% DFDB/polyol and 47% DFDB groups had similar amounts of bone formation. (allenpress.com)
We aimed to collect in vitro evidence of the ability of vital bone chips to promote new bone formation. (karaventures.com)
The rationale for this is that if bone chips remain vital in vivo, they could provide an environment promoting new bone formation through growth factors and cells. (karaventures.com)

Sclerostin null mice, and mice carrying an activated form of β-catenin were evaluated to understand how elevated Wnt signaling impacted edentulous ridge height and based on these data, a biomimetic strategy was employed to combine bone graft particles with a formulation of recombinant WNT protein. (jefferson.edu)
If graft particles were present, then osteoprogenitor cells attached to the matrix and gave rise to new bone that augmented edentulous ridge height. (jefferson.edu)

Graft particles alone did not stimulate osteoprogenitor cell proliferation. (jefferson.edu)
In this study, it was observed that cultured fibroblasts were enhanced cell proliferation and collagen fiber production by adding aragonite particles. (jarde.jp)

However, active bone remodeling with osteoclasts and osteoblasts working in synchrony continues to occur. (elsevier.es)
Different types of cells participate in the bone metabolism, such as osteoblasts, osteoclasts and osteocytes. (bvsalud.org)

Organic biocomponents of animals decompose and degrade during the fossilization process, and minerals in the groundwater are redeposited in the interstitial spaces, slowly transforming vertebrate bones and teeth into inorganic 'rock' 1 . (nature.com)
Their organic phase, normally a biodegradable biopolymer, holds the mechanical stress while their inorganic phase, a glass or ceramic, provides the needed bioactivity to recruit cells and produce bone. (ibecbarcelona.eu)
In many cases, the masking of the bioactive inorganic phase embedded in the organic matrix and undesired phase-detachments must be solved to increase efectiveness (2). (ibecbarcelona.eu)

Piezoelectric ceramics, such as BaTiO3, have gained considerable attention in bone tissue engineering applications thanks to their biocompatibility, ability to sustain a charged surface as well as improve bone cells' adhesion and proliferation. (manchester.ac.uk)

For example, decreased bone-mineral density has been correlated with increased risk for metastasis, and incomplete fracture healing has been shown to enhance bone metastasis. (provaeducation.com)
Bone fracture healing has become a serious problem in the last decades in part due to the increase in life expectancy (1). (ibecbarcelona.eu)

1 , - 4 This allograft is prepared by demineralizing bone in hydrochloric acid to expose bone morphogenic proteins (BMPs). (allenpress.com)

A connection between reduced bone health and the behavior of tumor cells is well-established. (provaeducation.com)
The presence of bone mineral reduced the growth of tumor cells in both settings. (provaeducation.com)
Cells could be seen on the surface of the bone chips, with spindle-shaped cells bridging the bone chip particles. (karaventures.com)
Altered ion transport in normal human bronchial epithelial cells following exposure to chemically distinct metal welding fume particles. (cdc.gov)
It is induced by INTERFERON-GAMMA and blocks the release of enveloped mammalian viruses by directly tethering nascent VIRAL PARTICLES to the membranes of infected cells. (bvsalud.org)

Most recently, in 2021, FiberCel Bone Matrix tissue products were linked to more than 100 tuberculosis illnesses. (aboutlawsuits.com)

Nanocomposites in bone tissue engineering applications. (dokumen.pub)

Available in a variety of options, MinerOss X is an anorganic bovine bone mineral matrix that is physically and chemically comparable to the mineral structure of human bone. (henryschein.com.hk)

Estroff led the necessary materials synthesis and characterization techniques of the different bone matrix models, which the team then used to investigate tumor cell behavior, first in vitro and then in vivo through mouse models. (provaeducation.com)
This research work aimed to investigate the parameters that influence the thermal degradation of Polyester-Banana peduncle fibre-reinforced composite incorporated with cow horn ash particle (CHAp) as a fire retardant additive and optimize the total heat produced for the smaller the better. (springeropen.com)
The U.S. Food and Drug Administration (FDA) issued a bone matrix product safety communication on September 12, indicating it is working with the U.S. Centers for Disease Control and Prevention to investigate a recent Mycobacterium tuberculosis (Mtb) outbreak among bone graft matrix recipients. (aboutlawsuits.com)
Objective: To investigate the bone apposition in implant surface treated with sandblasting and acid-etching. (bvsalud.org)

Furthermore, after implantation in vivo for four weeks, compared to those in control groups , the regenerated issue in the DBM-E7/CS group exhibited translucent and superior cartilage -like structures, as indicated by gross observation , histological examination, and assessment of matrix staining . (bvsalud.org)

Ionizing radiation is energy that is carried by several types of particles and rays given off by radioactive material, x ray machines, and fuel elements in nuclear reactors. (cdc.gov)
These radiation particles and rays carry enough energy that they can knock out electrons from molecules, such as water, protein, and DNA, with which they interact. (cdc.gov)

Furthermore, other portions of bone tissue a little more distant from the interface, which establish direct contact with the implant, are also damaged during the drilling process, and therefore, they also need to be remodeled. (elsevier.es)
However, implant failure and peri-implantitis are problems to be solved to provide long-term stability of the dental implants which depend not only on the integration into the surrounding bone [ 1 ], but also on the presence of the protective soft tissue sealing around the implant [ 2 ]. (hindawi.com)
Extension of this foreign-body response may infiltrate into the cement-bone or bone-implant interface and may result in loosening. (medscape.com)
The quality of contact within the implant-bone, cement-bone, or implant-cement interface determines the limits of the effective joint space. (medscape.com)
The percentages of bone-implant contact (BIC) and bone area between threads (BABT) were determined throughout histomorphometric analysis and bone apposition was detected in implants of both groups. (bvsalud.org)
Conclusion: Our data demonstrated that implants treated with the method II presented increase in the contact between bone and implant after 45 days compared to method I. Moreover, with concern to bone area between threads, it was observed an increased in the method II after 45 and 60 days. (bvsalud.org)
however, the implant does become surrounded by bone 23,25 . (bvsalud.org)
Many factors could affect the osseous healing of implants such as surface topography of biomaterial, the status of the bone/implant site, implant loading conditions, surgical technique and implant design 1,3,15,21 . (bvsalud.org)

We developed a 3D in vitro hypoxic bone chip organ culture model. (karaventures.com)

Our results indicate that bone chips in our 3D organ culture remain vital and may stimulate the growth of a bone-forming matrix. (karaventures.com)

Anatomy28

Organisms8

Diseases15

Chemicals and Drugs53

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Phenomena and Processes22

Disciplines and Occupations1

Technology, Industry, Agriculture6

Humanities1

Information Science3

Extracellular10

Regeneration7

Deposition3

Allograft bone3

Differentiation1

Porous2

Cortical bone1

Scaffold6

Autologous1

Cancellous bone chips2

Grafts2

Type I collag1

Autogenous bone chips3

Scaffolds3

Ceramic particles2

Wear particles7

Fibers2

Substitutes2

Tissues5

Regenerative1

Biomaterials1

Apatite2

Mineralization5

Cartilage and bone2

Resorption1

Autograft2

Defects2

Graft materials1

Physiological2

Articular cartilage1

Osteogenesis2

Clinical4

Periarticular1

Size4

Osseointegration5

Viable3

Osteocalcin2

Particulate1

Peri-implant1

Cellular2

Formation4

Ridge height2

Cell proliferation2

Osteoclasts2

Inorganic3

Proliferation1

Fracture2

BMPs1

Cells5

20211

Tissue engineering1

Chemically1

Investigate4

Vivo1

Rays2

Implant8

Vitro1

Stimulate1