• The management has undergone major changes over the past from nearly mandatory laparotomy with splenectomy, to an increase in non-operative management, with every effort made to preserve the spleen. (sages.org)
  • With better understanding of immunologic function of the spleen and the potential threat of severe post-splenectomy infections, surgeons began to perform parenchyma-sparing procedures. (sages.org)
  • As damaged red blood cells passing through the red pulp of the spleen are removed by splenic macrophages, splenectomy is one possible therapeutic approach to the management of severely affected patients. (haematologica.org)
  • Splenectomy has been suggested as a possible therapeutic approach to manage severely affected patients, based on the evidence that abnormal or damaged red blood cells passing through the spleen red pulp are removed by the splenic macrophage system. (haematologica.org)
  • A splenectomy is the surgical procedure that partially or completely removes the spleen. (wikipedia.org)
  • Therefore, removal of the spleen runs the risk of overwhelming post-splenectomy infection, a medical emergency and rapidly fatal disease caused by the inability of the body's immune system to properly fight infection following splenectomy or asplenia. (wikipedia.org)
  • For an infarcted spleen with any of the above-mentioned complications, splenectomy is required. (medscape.com)
  • Whereas a unilocular abscess can be managed successfully in select cases with percutaneous catheter drainage, some authors advocate splenectomy in all cases of splenic infarct and abscess, questioning the utility of preserving the residual, partially functioning spleen. (medscape.com)
  • If prednisone does not improve the condition, a splenectomy (removal of the spleen) may be considered. (health.am)
  • splenectomy (removal of damaged spleen), resection and anastomosis (cutting out and surgical connection) of a portion of his intestine, and reopening of his left renal artery. (khaleejtimes.com)
  • The spleen is one of the most frequently injured intraperitoneal organs, and management of splenic injuries may require splenectomy or, rarely, splenorrhaphy. (medscape.com)
  • Our aim was to evaluate the effect of total pancreatectomy with spleen preservation as well as splenectomy on the quality of life of the patients. (turkjsurg.com)
  • By saving spleen one can avoid post-splenectomy sepsis. (annalskemu.org)
  • Splenectomy is only carried out when the injury to the spleen and subsequent haemorrhage are life-threatening. (shiken.ai)
  • We performed partial gastrectomy, and the resected specimen was diagnosed as a needle tract seeding following EUS-FNA. (biomedcentral.com)
  • We performed partial gastrectomy, and the resected specimen was diagnosed as needle tract seeding due to EUS-FNA. (biomedcentral.com)
  • Herein, we reported two cases of needle tract seeding after EUS-FNA that were detected during surgery and diagnosed via partial gastrectomy. (biomedcentral.com)
  • The patient underwent robot-assisted laparoscopic distal gastrectomy, D1+ lymph node dissection, and Roux-en-Y reconstruction in November 2019. (biomedcentral.com)
  • We performed partial gastrectomy with pancreatic tail resection and splenectomy. (bvsalud.org)
  • The primary treatment approach to patients with malignancy-related gastrosplenic fistula has been splenectomy and partial gastrectomy. (consultant360.com)
  • Common indications for elective total pancreatectomy include chronic pancreatitis that is refractory to medical management, premalignant lesions (intraductal papillary mucinous neoplasms) where partial resection is not sufficient, pancreatic neuroendocrine tumors, and malignant tumors of the pancreas ( 2 - 4 ). (turkjsurg.com)
  • In addition, conversion total pancreatectomy is performed in patients who are scheduled for partial pancreatectomy but considered to be at high risk of developing pancreatic fistula in the postoperative period, and completion total pancreatectomy is also performed after complications such as postoperative bleeding and abscess development after partial pancreatectomy ( 7 - 9 ). (turkjsurg.com)
  • The purpose of this study was to define the hematologic response to total splenectomy (TS) or partial splenectomy (PS) in children with hereditary spherocytosis (HS) or sickle cell disease (SCD). (aku.edu)
  • However, except for hereditary spherocytosis for which the effectiveness of splenectomy has been well documented, the efficacy of splenectomy in other anemias within this group has yet to be determined and there are concerns regarding short- and long-term infectious and thrombotic complications. (haematologica.org)
  • Clinical and laboratory outcomes following total or partial splenectomy in patients with hereditary spherocytosis. (cdc.gov)
  • The resection of the pancreas can be partial or total, depending on the pathology. (turkjsurg.com)
  • citation needed] Splenectomy causes an increased risk of sepsis, particularly overwhelming post-splenectomy sepsis due to encapsulated organisms such as S. pneumoniae and Haemophilus influenzae which are no longer able to be destroyed. (wikipedia.org)
  • I have been the Cincinnati Children's site investigator for large multicenter studies investigating the role of partial versus total splenectomy for congenital blood disorders and laparotomy versus peritoneal drainage for NEC. (cincinnatichildrens.org)
  • However, the hospital stay was shorter for children who underwent laparoscopic cholecystectomy, appendectomy, nephrectomy, splenectomy, and surgery for intra-abdominal testis than for those who underwent open surgery. (medscape.com)
  • Thirteen patients underwent splenectomy with complete (9) or partial (4) response, but no consistent pattern of results was manifest. (bmj.com)
  • In our study, we retrospectively analyzed the data of patients diagnosed with pancreatic cancer, intrapapillary mucinous neoplasia, pancreatic neuroendocrine tumors, and chronic pancreatitis undergoing from partial to total pancreatic resections in our clinic between 12/2017 and 12/2022. (turkjsurg.com)
  • Complications, such as bleeding or pseudocyst formation, also may be amenable to splenic salvage using techniques of partial splenectomy. (medscape.com)
  • Most of these patient 58.33% had splenic salvage either by splenorrhaphy or partial splenectomy. (annalskemu.org)
  • Traditionally, such abscesses have been managed by means of splenectomy, which can be technically challenging because of the intense surrounding inflammation and because of the scar tissue that surrounds the abscess. (medscape.com)
  • [ 4 ] In certain circumstances, isolated splenic abscess can be treated with percutaneous drainage alone, and splenectomy can be avoided. (medscape.com)
  • Vaccination for S. pneumoniae, H. influenza and N. meningitidis should be given pre-operatively if possible to minimize the chance of overwhelming post-splenectomy infection (OPSI), a rapid-developing and highly fatal type of septicaemia. (wikipedia.org)
  • The Splenectomy in Congenital Hemolytic Anemia (SICHA) consortium registry collected hematologic outcomes of children with CHA undergoing TS or PS to 1 year after surgery. (aku.edu)
  • These bacteria often cause a sore throat under normal circumstances but after splenectomy, when infecting bacteria cannot be adequately opsonized, the infection becomes more severe. (wikipedia.org)
  • For elective open splenectomy, the only absolute contraindications are uncorrectable coagulopathy and severe cardiovascular disease that prohibits the administration of general anesthesia. (medscape.com)
  • It is concluded that in vivo isotope studies are of little value in predicting the benefit of splenectomy in thrombocytopenic patients, although they may demonstrate the mechanism of the thrombocytopenia, in particular the biphasic survival curve revealing separate 'immune' and 'hypersplenic' components of platelet destruction in ITP. (bmj.com)
  • Surgical splenectomy or partial splenic embolization (PSE) is a promising procedure for increasing the platelet count before interferon therapy. (go.jp)
  • Since steroids and immunoglobulin create a partial splenic dysfunction, through different mechanisms, we investigated whether combined treatment with both drugs could produce a rapid platelet count increase comparable to that of splenectomy. (karger.com)
  • We conclude that this combined therapy provides a prompt rise in platelet counts to a safe and hemostatic level and may offer a viable alternative for emergency splenectomy and its associated morbidity/mortality in many cases of childhood ITP. (karger.com)
  • However, until now, the preferred emergency management of life-threatening complications in children with ITP has been immediate splenectomy. (karger.com)
  • Hematologic outcomes after total splenectomy and partial splenectomy f" by Brian R. Englum, Jennifer Rothman et al. (aku.edu)
  • I'm also assessing the best approach to splenectomy for congenital blood disorders and determining the best surgical approach for NEC to provide better clinical outcomes. (cincinnatichildrens.org)
  • To address this potential fatal issue, a surgical procedure known as a splenectomy may be employed to remove the affected organ. (shiken.ai)
  • Immunosuppressive therapy will be given if the person does not respond to prednisone and splenectomy. (health.am)
  • Here, we present the case of a 28-year-old female presenting with generalized abdominal pain, constipation, and early satiety who had a delayed diagnosis of isolated splenic hydatid cyst which was partially treated with albendazole, eventually requiring splenectomy. (hcahealthcare.com)
  • Open splenectomy is performed in two major clinical scenarios: trauma and hematologic disease. (medscape.com)
  • Patients with various hematologic disorders may benefit from splenectomy. (medscape.com)
  • However, splenectomy should be avoided if possible, particularly in older patients, children, and patients with hematologic malignancy, to avoid the resulting permanent susceptibility to bacterial infections, increasing the risk of overwhelming postsplenectomy sepsis. (msdmanuals.com)
  • Overwhelming infection may occur as a complication of therapy with steroids or splenectomy, since they reduce the body's ability to fight infection. (health.am)
  • These vessels do not anastomose (connect) with each other, thus forming vascular segments that can be surgically removed whilst preserving the other areas (known as a subtotal splenectomy). (shiken.ai)
  • citation needed] Splenectomy also increases the severity of babesiosis, Splenectomized patients are more susceptible to contracting babesiosis and can die within five to eight days of symptom onset. (wikipedia.org)
  • Many of the altitude-related episodes in patients with sickle cell disease can be safely treated with supportive care rather than with splenectomy. (medscape.com)
  • Assessment of thrombocytopenic patients for splenectomy. (bmj.com)
  • The Hib antibody concentrations were investigated in 850 patients with thalassaemia major, of whom 437 had undergone splenectomy. (scialert.net)
  • We retrospectively evaluated the long-term effects of partial splenic embolization (PSE) with transarterial chemoembolization (TACE) in patients with HCC patients accompanied by thrombocytopenia. (hindawi.com)
  • The patients with encephalopathy, ascites, variceal bleeding, previous splenectomy and small liver had significantly higher incidences of portal vein thrombosis than the others. (nih.gov)
  • 2 of 3 patients had a partial response to 2′deoxycoformycin. (ashpublications.org)
  • Ils ont été répartis en deux groupes : 12 patients souffrant d'une thrombocytopénie à médiation immunitaire (groupe 1) et 12 patients atteints d'une thrombocytopénie à médiation non immunitaire (groupe 2). (who.int)
  • asymptomatic cas'e of congenital splenic cvst which was treated bir partial splenectomy. (selcukmedj.org)
  • Although partial thickening of the gastric wall was seen retrospectively in a 1-year postoperative CT scan, it was reviewed within normal limits by a radiologist at that time (Fig. 2 ). (biomedcentral.com)
  • Over the past 20 years, partial splenic embolization (PSE) has been an interventional radiological treatment for thrombocytopenia due to hypersplenism [ 3 , 4 ]. (hindawi.com)
  • As no randomized clinical trials, case control or cohort studies regarding splenectomy in these disorders were found in the literature, recommendations for each disease were based on expert opinion and were subsequently critically revised and modified by the Splenectomy in Rare Anemias Study Group, which includes hematologists caring for both adults and children. (haematologica.org)
  • Our recommendations are intended to enable clinicians to achieve better informed decisions on disease management by splenectomy, on the type of splenectomy and the possible consequences. (haematologica.org)
  • Roux-en-Y gastric bypass - A small pouch is created from the stomach and connects directly to the small intestine. (lgphysicians.com)
  • An emergency laparoscopic partial splenectomy was carried out. (sages.org)
  • Splenectomy was done in 33.33% of cases and 8.33% were managed conservatively by not operating. (annalskemu.org)