• Current clinical guidelines for PAH recommend upfront double oral combination therapy and this study confirms that initial oral dual combination with macitentan and tadalafil is beneficial in those patients. (jnj.com)
  • These are determined by a careful clinical examination of the patient before ordering the radiographic survey. (trnds.co)
  • S . zooepidemicus infections should be considered in patients who have severe clinical illness and report guinea pig exposure. (cdc.gov)
  • They analyzed the literature on the measurement properties of patient-reported joint counts in clinical practice and stated that their group was the first to consider agreement. (jrheum.org)
  • 2 These findings highlight the potential of patients acting as their own observer in measuring joint counts between clinic visits over time, and of patient self-assessment as an outcome measure in clinical trials. (jrheum.org)
  • 5 , 6 The review is a timely topic of relevance to patients, clinical practice, and research, but some limitations specific to this study were identified. (jrheum.org)
  • Available ob-gyn tools are anchored in a clinical setting, costly, and not always clearly understood by the patient. (nae.edu)
  • Our clinical experiences with LS has shown that it reduces conventional inotropic agents dosages and could be a satisfactory agent in myocardial depression therapy which occurred in CPB surgery intraoperatively also in pediatric patients. (ispub.com)
  • Patients are followed for 2 years with comprehensive clinical and laboratory examinations. (biomedcentral.com)
  • Nevertheless, the criteria have been widely used in the clinical setting, even in the assessment of patients with recent-onset arthritis, and it can be assumed that rheumatologists often consider the fulfilment of these criteria when evaluating the diagnosis and/or prognosis in their arthritis patients [ 6 ]. (biomedcentral.com)
  • This goal is achieved reliability, reproducibility, clinical applicability, clinical flex- for many patients receiving chemotherapy or radiation ibility, clarity, multidisciplinary process, review of evidence, therapy, and is based on clinical and basic research that has and documentation.4 steadily improved the control of emesis over the last 20 In formulating recommendations for antiemetic usage, years. (marysfamilymedicine.org)
  • not intended to supplant physician judgment with respect to As antiemetic usage has grown, the classes of agents available particular patients or special clinical situations. (marysfamilymedicine.org)
  • Additionally, managing special and difficult emetic regarding emesis in cancer care have been addressed by problems and selecting the proper antiemetic approach necessi- clinical trials. (marysfamilymedicine.org)
  • As ongoing research is completed, several aspects of clinical care. (marysfamilymedicine.org)
  • appreciates these issues and their applicability to the manage- to interventions performed in the context of clinical ment of patients with cancer. (marysfamilymedicine.org)
  • At both 30 minutes and 2 minutes before intratracheal suctioning, there was no difference in electroencephalographical or clinical signs in patients who had or had not received drugs 10 minutes before suctioning. (biomedcentral.com)
  • However, clinical indications for drug administration were not reflected by these electroencephalographical parameters, and barely by sedation level before drug administration or tracheal suction. (biomedcentral.com)
  • Although clinical aspects of acute intermittent porphyria attacks have been documented, the experience of patients is not well known, particularly for those more severely affected patients who experience frequent attacks. (springer.com)
  • These new results add to the body of data supporting the Oncotype DX test, which includes multiple validation studies demonstrating its unique ability to predict chemotherapy benefit along with prospective evidence in more than 70,000 patients both with N0 and N+ disease 3-8 , showing that the test accurately predicts clinical outcomes. (prnewswire.co.uk)
  • The first study 1 presented at ESMO is research from Ireland assessing the impact of the Oncotype DX test on treatment decisions in routine clinical practice for early breast cancer patients whose disease has spread to the lymph nodes (one to three positive nodes). (prnewswire.co.uk)
  • Develop a clinical prediction rule for identifying patients with low back pain who improve with spinal manipulation. (researchgate.net)
  • Development of clinical prediction rules for classifying patients with low back pain who are likely to respond to a particular intervention, such as manipulation, would improve clinical decision-making and research. (researchgate.net)
  • Several clinical, radiological and laboratory variables have been reported as prognostic factors in patients with early RA: the number of swollen joints, the number of tender joints, functional indices, erosions on radiology, a positive rheumatoid factor test and the presence of the genetic marker HLA-DR4. (bmj.com)
  • To characterise the clinical outcome of newborns with gastroschisis (GS) in a neonatal intensive care unit. (bvsalud.org)
  • For the clinical variables, calibrated on the samples, either using all the clinical param- eters or the Nottingham Prognostic Index (NPI) parameters, the areas under the receiver operating characteristics (ROC) curve were 0.78 and 0.79, respectively. (lu.se)
  • Our data have provided evidence for a comparable prediction of clinical outcome in CMF-treated breast cancer patients using conventional clinical variables and gene expression based markers. (lu.se)
  • Adjuvant polychemotherapy (e.g. with 58% to 68%) for patients under the age of 50.1 Besides an cyclophosphamide, methotrexate and 5-fluorouracil (CMF)) or improvement in clinical outcome, these figures indicate that anthracycline-containing regimes, produce substantial reduc- a large proportion of the patients will never recur after the tion in recurrence and mortality. (lu.se)
  • The key to reducing the clinical perspective, could be managed inappropriate admissions is improving the on a less intensive health care level" [ 1 ]. (who.int)
  • Causes included a poliomyelitis- to describe the clinical features, mechanisms, and short- like syndrome in 27 (84%) patients and a Guillain- term outcomes. (cdc.gov)
  • All patients had IgM antibodies detected in paralysis in WNV neuroinvasive disease remains acute-phase serum samples by IgM antibody-capture unknown, and the clinical features of WNV-associated res- enzyme-linked immunosorbent assay at the Colorado piratory weakness have not been characterized. (cdc.gov)
  • Twenty-seven patients (84%) had asymmetric weak- dardized demographic, clinical, and medical history data ness consistent with a poliomyelitislike syndrome, 4 (13%) were obtained from patient interviews and medical had symmetric ascending weakness with sensory abnor- records. (cdc.gov)
  • METHODS Patients referred to the outpatients clinic between 1995 and 1996, with a symptom duration of less than three years and fulfilling the American Rheumatism Association 1987 revised criteria for RA within one year after entry were included. (bmj.com)
  • It was not until nearly a century later, in 1977, that Kennedy and Knudson described a patient with these classic findings, and coined the term "hepatopulmonary syndrome" 5. (rarediseases.org)
  • They cannot for antiemetic treatment, the number of agents, and the indica- be considered to be inclusive of all proper methods of care or tions for antiemetics have all increased as well. (marysfamilymedicine.org)
  • Patients and methods proportion of the patients will recur despite treatment with adjuvant polychemotherapy. (lu.se)
  • Practice parameters for diagnosis and evaluation of dementia, as published by the American Academy of Neurology (AAN), consider structural brain imaging to be optimal. (medscape.com)
  • However, given the high prevalence and often multifactorial nature of dyspnea in cirrhotic patients, this complaint is easily overlooked, and HPS patients reportedly have respiratory symptoms for a mean of 4.8 years before diagnosis 7. (rarediseases.org)
  • 2,3 Despite recent advances, PAH is a serious, progressive disease with no cure, and one in three patients die within five years of diagnosis. (jnj.com)
  • Epilepsy is a disease that creates many problems for people with such a diagnosis in the enjoyment of their social rights. (intechopen.com)
  • The diagnosis of botulism was not made until nearly 2 weeks after symptom onset when both patients were hospitalized in the same health care facility. (cdc.gov)
  • On July 27, a physician suspected botulism as the likely diagnosis after learning that patient A had shared a meal with patient B, who had recently been admitted for neurologic dysfunction. (cdc.gov)
  • In univariable and multivariable survival analysis, tumor stage, tumor grade, and patients' age at diagnosis, but not presence/absence of a postmenopausal bleeding, were associated with disease free and overall survival. (biomedcentral.com)
  • Asymptomatic patients with endometrial cancer have a higher rate of well differentiated tumors compared to patients with a postmenopausal bleeding prior to diagnosis. (biomedcentral.com)
  • As in other malignancies, it can be hypothesized that an earlier diagnosis leads to a lower stage of disease, a less radical surgery, a therapy with less side effects and, subsequently, a better prognosis of affected patients. (biomedcentral.com)
  • Our questions referred to the characteristics of WD patients at the different sites and internal procedures regarding diagnosis, therapy and follow-up. (biomedcentral.com)
  • Health Care Survey, which measures health care utilization across various types of an hour in 2002. (cdc.gov)
  • The objective of this study was to identify and compare predictors of three relevant outcomes of chronic arthritis in a cohort of very early arthritis patients. (biomedcentral.com)
  • The Norwegian Very Early Arthritis Cohort (NOR-VEAC) includes adult patients with at least one swollen joint of ≤16 weeks' duration. (biomedcentral.com)
  • A prospective, cohort study of patients with nonradicular low back pain referred to physical therapy. (researchgate.net)
  • OBJECTIVE: The aim of this study was to determine inpatient health care utilization in an incident cohort of patients with systemic lupus erythematosus (SLE) compared with the general population. (cdc.gov)
  • The study cohort comprised patients who had survived for at least 5 years (60 months) after undergoing sphincter- preserving radical resection of pathologically diagnosed rectal adenocarcinoma within 15 cm of the anal verge in the Department of Gastrointestinal Surgery, Peking University People's Hospital from January 2005 to May 2016. (bvsalud.org)
  • It is indicated for pulmonary arterial hypertension (WHO Class I) in patients with NYHA Class III or IV symptoms to improve exercise tolerance and symptoms and to delay deterioration. (medscape.com)
  • Bosentan is an endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension (PAH) in patients with WHO class III or IV symptoms. (medscape.com)
  • The survey contained radiographs of pulpally involved primary teeth, a description of associated signs/symptoms, and a medical history of the patient who was positive for a type of CHD. (trnds.co)
  • An adult man (patient 1) from northern Virginia, USA arrived at a hospital in late February 2013 with influenza-like symptoms, worsening bilateral thigh pain and stiffness, nausea, shivering, fatigue, diarrhea, sweating, and headache. (cdc.gov)
  • Eisenmenger syndrome was initially described in 1897, when Victor Eisenmenger reported on a patient with symptoms of dyspnea and cyanosis from infancy who subsequently developed heart failure and succumbed to massive hemoptysis. (medscape.com)
  • The next day she returned to the same ED with worsening symptoms, including inability to swallow, double vision on lateral gaze, and decreased sensation in her right arm. (cdc.gov)
  • On July 19, patient A was transferred to the neurologic intensive care unit (ICU) of facility B with worsening bulbar symptoms, where she was intubated for impending respiratory failure and treated with 5 days of intravenous immunoglobulin. (cdc.gov)
  • Purpose: To identify symptoms/distress among patients with colorectal buy BTSA1 cancer undergoing chemotherapy, from the viewpoint of the next of kin, and to establish whether there are any barriers to reporting these problems. (rafinhibitors.com)
  • Eighteen patients (95%) experienced both attack and chronic symptoms. (springer.com)
  • Patients described attacks as the onset of unmanageable symptoms that generally lasted 3-5 days requiring hospitalization and/or treatment. (springer.com)
  • In this study population of acute intermittent porphyria with frequent attacks, most patients had symptoms during and between attacks. (springer.com)
  • Acute intermittent porphyria (AIP) is a rare, often mis/underdiagnosed, inherited metabolic disease characterized by acute potentially life-threatening attacks and in some patients, chronic debilitating multi-systemic symptoms and manifestations that negatively impact patients' daily functioning and quality of life. (springer.com)
  • This qualitative research study undertook one-to-one interviews with 19 patients with AIP to characterize their symptoms and the impact of the disease burden on their daily lives. (springer.com)
  • Patients with AIP having frequent attacks may have both attack and chronic disease symptoms, suggesting in some patients, AIP is not just an 'intermittent' disease but also has chronic symptoms, many of which are disabling. (springer.com)
  • Patients present with signs and symptoms that are secondary to widespread dysfunction across the central, peripheral, and autonomic nervous system [ 3 , 4 ]. (springer.com)
  • The prevalence of LARS and major LARS in patients who had survived more than 5 years after surgery, correlation between postoperative time and LARS score, and whether postoperative time was a risk factor for major LARS and LARS symptoms were analyzed. (bvsalud.org)
  • Conclusions: Patients with rectal cancer who have survived more than 5 years after sphincter-preserving surgery still have a high prevalence of LARS. (bvsalud.org)
  • 8 ], targeting for review only patients with hospital utilization has been described as a high average length of stay [ 9 ] and pa- the "hospitalization of patients who, from tient self-referral [ 10 ]. (who.int)
  • Since this decline in personal contact in the clinic could be permanent, patient self-assessment could fill this gap. (jrheum.org)
  • Twelve consecutive patients with Alzheimer's disease (seven male and five female patients) from the memory outpatient clinic of the Academisch Ziekenhuis Vrije Universiteit were asked to participate. (ajnr.org)
  • However the need for serial randomized controlled studies in pediatric patient about the use of LS is indisputable. (ispub.com)
  • Although failure to thrive (FTT) is a relatively common presentation in the emergency department, many emergency clinicians are unsure of how to properly work up a pediatric patient with this condition. (ebmedicine.net)
  • Positive ACPA status and small joint arthritis were consistent predictors of three relevant outcomes of chronic arthritis in very early arthritis patients. (biomedcentral.com)
  • other socio-demographic multidisciplinary care for stroke survivors. (who.int)
  • The formation of central units and networks in a multidisciplinary setting should be evaluated to improve the care of WD patients. (biomedcentral.com)
  • String-of-pearls sign in the left lower lobe in a patient with cystic fibrosis. (medscape.com)
  • pneumonia in the right lower lobe was diagnosed. (cdc.gov)
  • all lymphocytic subgroups are dramatically reduced in critically ill patients, while CD4/CD8 ratio remains normal. (biomedcentral.com)
  • Sedative and analgesic drugs are frequently used in critically ill patients. (biomedcentral.com)
  • Electrodes for monitoring bispectral index and entropy were placed on the foreheads of 44 critically ill patients requiring mechanical ventilation and who previously had no brain dysfunction. (biomedcentral.com)
  • This precludes incorporation of entropy and bispectral index as target variables for sedation and analgesia protocols in critically ill patients. (biomedcentral.com)
  • Pain, physical discomfort and anxiety are common in critically ill patients. (biomedcentral.com)
  • TAILORx - the largest randomised adjuvant breast cancer treatment trial ever conducted - definitively confirmed the value of the Oncotype DX test for precisely guiding adjuvant chemotherapy decisions in patients with early-stage, node-negative breast cancer. (prnewswire.co.uk)
  • This was recently acknowledged by Germany's health technology assessment body - the Institute for Quality and Efficiency in Health Care (IQWiG) - which concluded that only the Oncotype DX test has sufficient evidence to guide breast cancer adjuvant chemotherapy decisions based on the TAILORx study results. (prnewswire.co.uk)
  • Objective: Knowing the properties of new radiographic films is essentially important, because from this evaluation depends the learning of such films, directly affecting the radiation dose received by the patient in radiographic examination. (bvsalud.org)
  • GENEVA , Oct. 22, 2018 /PRNewswire/ -- Results from two prospective decision impact studies 1,2 , presented at the ESMO 2018 Congress , October 19-23 in Munich, Germany , further support the utility of the Oncotype DX Breast Recurrence Score ® test to optimise chemotherapy recommendations in patients with early-stage, hormone-receptor positive, HER-2 negative breast cancer with or without lymph node involvement. (prnewswire.co.uk)
  • Oncotype DX identifies patients who can safely be spared chemotherapy toxicity and side effects. (prnewswire.co.uk)
  • In particular, results demonstrate that the test provides definitive evidence about the magnitude of chemotherapy benefit based on prospective long-term patient follow up, identifying the vast majority of women who receive no substantial benefit from chemotherapy, as well as the important minority of women for whom chemotherapy can be life-saving. (prnewswire.co.uk)
  • According to treatment guidelines in the regional care pro- recur in spite of chemotherapy. (lu.se)
  • Overall, the most common complaint is an insidiously progressive shortness of breath (dyspnea) at rest or upon exertion, reported in 95% of patients and usually developing after years of liver disease2. (rarediseases.org)
  • In a majority of patients, dyspnea and hypoxemia progress over time 8. (rarediseases.org)
  • Patients with pulmonary arterial hypertension (PAH, WHO Group 1) taking this combination showed hemodynamic improvement, as well as improvements in functional parameters and risk profiles. (jnj.com)
  • Six hours later we started to reduce the analogous inotropic support (dopamine 10µg/kg/min, dobutamine 10µg/kg/min, adrenalin 0.5mg/h) since the hemodynamic parameters were satisfactory. (ispub.com)
  • Patient with a history of cystic fibrosis has complete right lung atelectasis with extreme bronchiectasis. (medscape.com)
  • Patients with cystic fibrosis (CF) show decreased plasma concentrations of antioxidants due to malabsorption of lipid soluble vitamins and consumption by chronic pulmonary inflammation. (hindawi.com)
  • Approximately 85-90% of patients with cystic fibrosis (CF) suffer from pancreatic insufficiency (PI), which predisposes them to malabsorption of lipids and lipid soluble vitamins leading to a deficiency of nonenzymatic antioxidants [ 2 ]. (hindawi.com)
  • The aim of the present study was to qualitatively characterize the experience of patients with acute intermittent porphyria who have frequent attacks, as well as the impact of the disease on daily living. (springer.com)
  • Among the parameters that characterize a solar cell and define its power-conversion efficiency, the fill factor is the least well understood, making targeted improvements difficult. (limkinase-signal.com)
  • [ 9 ] The AAN suggests that neuroimaging may be most useful for patients with dementia characterized by early onset or an unusual course. (medscape.com)
  • Interestingly, relatively few studies are available investigating whether asymptomatic patients with endometrial cancer have a better prognosis than those detected after the onset of a postmenopausal bleeding. (biomedcentral.com)
  • Patients diagnosed with asymptomatic endometrial cancer showed a significantly better 5-year overall survival rate than the patients diagnosed after the onset of postmenopausal bleeding. (biomedcentral.com)
  • Late-onset sepsis occurred in 58% of patients and was related to the infection of the central venous catheter in 37.9% of cases. (bvsalud.org)
  • SETTING: Acute-care hospitals. (cdc.gov)
  • Additional efforts are needed to expand adoption of leading practices across all acute-care hospitals with the greatest need in smaller hospitals. (cdc.gov)
  • Driven by changes in reimbursement for acute care that began in 1983 (6,7), the number of short-stay postacute care patients increased significantly (3,4,8). (cdc.gov)
  • These data are meaningful because improvement of PVR, an important indicator of right ventricular function, is a key treatment goal. (jnj.com)
  • Levosimendan (LS), a new inodilator used in the treatment of decompensate heart failure, has been reported to be effective in patients with high perioperative risks, with abnormal left ventricular function, and who face difficulties in weaning off cardiopulmonary bypass. (ispub.com)
  • After the excision of the pericardial patch, the repair of the right ventricular outflow was done with e-PTFE graft. (ispub.com)
  • LS is distinguished from other inotropic agents by this dual mechanism and considered as a good choice in high-risk patients undergoing cardiac surgery. (ispub.com)
  • might have additive value to established risk factors in the preoperative assessment of patients undergoing cardiac surgery. (limkinase-signal.com)
  • It is important to recognise as early as possible the factors that predict a poor outcome in order to treat patients with such characteristics more aggressively than the mild cases. (bmj.com)
  • The potential for improved outcome in patients with hepatic metastases from colon cancer: A population-based study. (cancercentrum.se)
  • A population-based study on the management and outcome in patients with locally recurrent rectal cancer. (cancercentrum.se)
  • For example, only 27.00% of registered patients had an ophthalmic examination and only 71.10% of patients with proliferative retinopathy had laser therapy. (jmir.org)
  • Anterior and posterior segments, together with neuro-ophthalmic disorders were found among stroke patients in this study. (who.int)
  • It is also advised that internists should refer hypertensive patients for routine ophthalmic screening. (who.int)
  • OBJECTIVE To find disease parameters that can predict the functional capacity of patients with early rheumatoid arthritis (RA) at the first visit to the rheumatologist and one year after entry. (bmj.com)
  • OPSUMIT, in combination with tadalafil, showed a 47% reduction of the primary endpoint of mean pulmonary vascular resistance (PVR) at week 16 compared with baseline in patients with PAH," said Olivier Sitbon, M.D., Ph.D., principal investigator and professor of respiratory medicine at Université Paris-Sud. (jnj.com)
  • These drugs can be effective in reversing reactive pulmonary vasoconstriction and can, therefore, lower pulmonary vascular resistance, decrease afterload, reduce the right ventricle, and reduce right-to-left shunting. (medscape.com)
  • Systemic-to-pulmonary communications are usually harmless prenatally because the high pulmonary vascular resistance of the fetus limits left-to-right shunting. (medscape.com)
  • Few if any human case-patients with S . zooepidemicus infection have documented guinea pig exposure even though S . zooepidemicus infections have been described in guinea pigs since 1907 ( 4 ). (cdc.gov)
  • Chronic pulmonary infection of CF patients results in a chronic activation of immune cells, especially neutrophilic granulocytes, leading to a permanent production of free radicals and lipid peroxidation (LPO) products, thus triggering inflammation [ 3 - 6 ]. (hindawi.com)
  • Patients who had undergone local resection, had permanent stomas, recurrent intestinal infection, local recurrence, history of previous anorectal surgery, or long- term preoperative defecation disorders were excluded. (bvsalud.org)
  • During the summer and fall of 2003, we identified with Guillain-Barré-like syndrome, had acute respiratory patients with acute weakness and WNV infection from failure that required endotracheal intubation. (cdc.gov)
  • Cardiac output is a global blood flow parameter of interest in hemodynamics, the study of the flow of blood. (wikipedia.org)
  • The OPTIMA (c O mbination thera P y of maci T entan and tadalaf I l in patients with newly diagnosed pul M onary A rterial Hypertension) study was a prospective, multicenter, single-arm, open-label, Phase IV trial evaluating the efficacy, safety, and tolerability of initial oral combination therapy with OPSUMIT and tadalafil in patients with newly diagnosed PAH. (jnj.com)
  • A total of 46 patients were enrolled in the study. (jnj.com)
  • Three patients discontinued treatment due to AEs and three patients died during the study. (jnj.com)
  • 9 , 10 , 11 Further, reliability parameters are highly dependent on the heterogeneity of the study sample, since reliability can also be explained as the ability of a measurement to distinguish between patients. (jrheum.org)
  • 9 , 10 , 11 Based on the results of the Quality Appraisal of Diagnostic Reliability (QAREL) checklist and Tables 1-3 in the study of Rampes, et al , 2 it could be assumed that the patient populations of the 14 included studies were representative of the population of interest, were stable, and contained some degree of heterogeneity. (jrheum.org)
  • The goal of our study including 137 patients was research of effects of the spinal and general anaesthesia while monitoring the Bispectral Index (BIS) during the surgery. (nel.edu)
  • Our results are promising and we continue in the study, monitoring also other possible parameters. (nel.edu)
  • β -Carotene is a major source of retinol and therefore is of particular significance in CF. The aim of this study was to investigate the effect of daily intake of red palm oil (RPO) containing high amounts of β -carotene on the antioxidant levels in CF patients. (hindawi.com)
  • This study aimed to measure the levels of volatile sulfur compounds and investigate the occurrence of halitosis in patients with gingivitis and periodontitis. (nature.com)
  • One-hundred-and-four participants (52 females and 52 males, mean age: 46.49 ± 16.03 years) were enrolled in this cross-sectional study, comprising 33 healthy controls, 43 patients with gingivitis, and 28 patients with periodontitis. (nature.com)
  • This study aimed to determine whether a greater extent of resection would increase the overall 5-year and 10-year survival of patients with low-grade gliomas. (biomedcentral.com)
  • This study was conducted to evaluate whether asymptomatic patients with endometrial cancer have a better prognosis than symptomatic patients with endometrial cancer diagnosed after postmenopausal bleeding. (biomedcentral.com)
  • In the present multi-center study, the effect of the presence of postmenopausal bleeding on prognosis was evaluated retrospectively in 605 patients with endometrial cancer using patients' files. (biomedcentral.com)
  • The aim of the present study was to estimate whether asymptomatic patients with endometrial cancer have a better prognosis than symptomatic patients with endometrial cancer diagnosed after postmenopausal bleeding in a large series of postmenopausal patients with endometrial cancer in a multi-center study. (biomedcentral.com)
  • We applied functional MR imaging with a learning task in healthy elderly volunteers and in patients with Alzheimer's disease to study brain activation during memory performance. (ajnr.org)
  • In the present study, we applied paradigms involving the visual encoding of complex color pictures and visual associations of line drawings to study the activation pattern in patients with mild to moderate forms of Alzheimer's disease and in healthy elderly control volunteers. (ajnr.org)
  • From the 74 patients with Recurrence Score ® results included in the analysis, the study found that in 64% of cases oncologists thought the test's result substantially changed treatment recommendations. (prnewswire.co.uk)
  • These changes in treatment recommendations would be even greater in patients with N0 disease applying decision-making criteria (Recurrence Score groups) based on results from the recently published landmark TAILORx study. (prnewswire.co.uk)
  • RESULTS 133 patients were included in the study. (bmj.com)
  • Objective: In this study, we aimed to investigate the prevalence of low anterior resection syndrome (LARS) in patients who had survived for more than 5 years after sphincter-preserving surgery for rectal cancer and to analyze its relationship with postoperative time. (bvsalud.org)
  • Patients with a testicular mass may present with a painless lump or scrotal pain, which can range from severe pain to a dull ache that worsens with exercise. (aafp.org)
  • Patients with testicular torsion often present with sudden, severe, unilateral scrotal pain that is often associated with nausea and vomiting. (aafp.org)
  • Advances in the medical treatment of patients with severe pulmonary hypertension may improve survival in patients with Eisenmenger syndrome and may potentially reverse the process in selected patients to a point at which they again become candidates for surgical repair. (medscape.com)
  • The rationale behind this approach is derived from the hypothesis that the physician at the time of a disease-modifying anti-rheumatic drug (DMARD) prescription assumes the patient to be at high risk of developing chronic and severe disease. (biomedcentral.com)
  • Of the 63 patients with left sided stroke, 2 (2.4%), 4(4.8%) and 57(68.7%) had severe, moderate and mild and normal visual impairment respectively while of the 20 patients with right sided stroke, 3(3.6%) each had severe and moderate visual impairment and 14(16.9%) had normal or mild visual impairment. (who.int)
  • Segelman J, Singnomklao T, Hellborg H, Martling A. Differences in MDT assessment and treatment between patients with stage IV colon and rectal cancer. (cancercentrum.se)
  • At the tertiary care center, the patient was treated for septic shock secondary to rhabdomyolysis, placed on a ventilator several times to treat respiratory failure, and underwent bilateral thigh fasciotomy and debridement several times to treat necrotizing fasciitis. (cdc.gov)
  • After treatment at the tertiary facility for several months, the patient was discharged to a rehabilitation hospital for another month. (cdc.gov)
  • An elderly man from central Virginia (patient 2) who was related to patient 1 was admitted to a hospital, 1 week after patient 1 was hospitalized, with nausea, vomiting, chills, difficulty breathing, weakness, abdominal and chest pain, and icterus. (cdc.gov)
  • On the evening of July 15, 2014, patient A, an otherwise healthy woman aged 20 years, was evaluated at the emergency department (ED) of hospital A, reporting 12 hours of worsening throat pain. (cdc.gov)
  • Since the well tolerance of the myocardium, we were able to stop the other inotropic drug infusions after 48 hours and the patient was discharged from the hospital 10 days after the surgery. (ispub.com)
  • Consecutive new stroke patients seen at the Federal Teaching Hospital, Lokoja over a 3-month period were studied. (who.int)
  • In this paper, we present the results of toxicological analyses of preserved brain tissue and bone samples from the remains of the seventeenth century patients of the Ospedale Maggiore , the main hospital in Milan and one of the most innovative hospitals in Europe from the Renaissance period. (nature.com)
  • It became the main hospital of the city in the sixteenth century and a model during the Renaissance for similar institutions across Italy, and even Europe, because of its innovative and avant-garde free medical assistance to the poor, care of the ill and hospital organization. (nature.com)
  • Annex to the hospital, the crypt of the Church of the Beata Vergine Annunziata was used as place of burial for the deceased patients of the Ca' Granda for almost the entire span of the seventeenth century. (nature.com)
  • Another extraordinary aspect of this context is the presence of historical archives, still preserved, concerning the administration and organization of the hospital, patient care and the pharmacopoeia (drugs) used in the hospital to treat the patients' diseases. (nature.com)
  • Should this patient be admitted to the hospital or discharged home? (ebmedicine.net)
  • The reasons believed to contribute most to inappropriate admission and hospitalization were the inability of the patient's family to take care of the patient, to satisfy the patient's request, and the absence of someone to get the patient out of the hospital. (who.int)
  • Statistics are presented on selected assistance to paid health care workers characteristics of nursing homes using voluntary workers and the services they and other ancillary staff employed in perform. (cdc.gov)
  • 1 In times of increasing delivery of remote care, accelerated due to the coronavirus disease 2019 (COVID-19) pandemic, the role of patients in the monitoring of disease activity becomes more topical. (jrheum.org)
  • This is called hepatopulmonary syndrome (HPS) and it occurs in approximately 5-32% of patients with scarring of the liver (cirrhosis)1. (rarediseases.org)
  • After replacing the diseased liver in HPS patients, the lungs return to normal within approximately one year3. (rarediseases.org)
  • Today, HPS is a well-recognized and relatively common complication of liver disease of varying causes (though overall it remains a rare disease, as only patients with liver disease can get it). (rarediseases.org)
  • The vast majority of HPS patients (82%) initially present with features of their liver disease, while a minority (18%) present with lung (pulmonary) complaints first. (rarediseases.org)
  • In total, approximately one-third of the estimated WD patients in Germany are seen annually in the outpatient clinics of these departments (approx. (biomedcentral.com)
  • Various studies have looked at the appro- care beds and access to outpatient services priateness of hospitalization. (who.int)
  • Among patients who received drugs, electroencephalographical parameters returned to baseline more rapidly. (biomedcentral.com)
  • A variety of imaging modalities, including structural and functional magnetic resonance imaging (MRI) and positron emission tomography (PET) studies of cerebral metabolism, have shown characteristic changes in the brain of patients with Alzheimer disease in prodromal and even presymptomatic states. (medscape.com)
  • Coronal, T1-weighted magnetic resonance imaging (MRI) scan in a patient with moderate Alzheimer disease. (medscape.com)
  • 4 Rampes, et al examined the extent to which self-reported TJC/SJC between patients with RA and HCPs are sufficiently reproducible to be a justified option in calculating disease activity. (jrheum.org)
  • Patient A had been treated for 12 days for suspected autoimmune disease. (cdc.gov)
  • The SNDR is an effective electronic medical file that can provide epidemiologic, economic, and geographic reports that can be used for disease management and health care planning. (jmir.org)
  • It is a useful tool for research and disease health care quality monitoring. (jmir.org)
  • The development of computerized applications and telecommunication for computer-based health care management tools has increased and helped patients, physicians, and health institutes better manage health and disease. (jmir.org)
  • The nutritional status of CF patients is recognized as strong predictor of the severity of CF lung disease. (hindawi.com)
  • Features such as erosions and rheumatoid nodules reflect established disease and their value as part of the criteria is questioned in the era of early aggressive treatment, when the aim is to treat patients before bone damage occurs. (biomedcentral.com)
  • These results suggest that H 2 S can be used as a biomarker of halitosis in patients with periodontal disease. (nature.com)
  • In addition, patients' requirements for sedative and analgesic drugs vary substantially during the disease process and during therapeutic and supportive interventions. (biomedcentral.com)
  • The purpose was to determine the feasibility of functional MR imaging during a learning task in healthy elderly volunteers and in patients with Alzheimer's disease and to test our hypothesis that brain activation is decreased in the medial temporal lobe (MTL) memory system in patients with Alzheimer's disease compared with control volunteers. (ajnr.org)
  • In 12 patients with mild to moderate forms of Alzheimer's disease and 10 elderly control volunteers, activation of the MTL memory system was studied. (ajnr.org)
  • Functional MR imaging with a learning task seems feasible in elderly volunteers and in patients with Alzheimer's disease. (ajnr.org)
  • Patients with Alzheimer's disease characteristically show a profound anterograde amnesia that becomes evident during the early stages of the disease (1) . (ajnr.org)
  • First, we wanted to know whether functional MR imaging with a learning task was feasible in elderly healthy volunteers and in patients with Alzheimer's disease. (ajnr.org)
  • Second, we wanted to compare brain activation of elderly volunteers and patients with Alzheimer's disease. (ajnr.org)
  • Affected patients must obtain lifelong medical treatment, as the disease is fatal if untreated. (biomedcentral.com)
  • Assessments of the duration of morning stiffness, the Disease Activity Score (DAS: a composite score based on erythrocyte sedimentation rate (ESR), number of painful and swollen joints and patient global assessment), pain (Visual Analogue Scale), the Arthritis Impact Measurement Scale (AIMS) and the Health Assessment Questionnaire (HAQ) were performed every three months. (bmj.com)
  • In most countries, patients with RA are initially seen by general practitioners who have less experience in diagnosing RA because of the low disease prevalence, subsequently appropriate referral and treatment may be delayed. (bmj.com)
  • Firstly, to test whether the duration of complaints and various disease parameters correlate with the functional status at first visit to the rheumatologist. (bmj.com)
  • The National Institute for Occupational Safety and Health (NIOSH) and the Centers for Disease Control and Prevention (CDC) recommend the use of a NIOSH-certified N95 or better respirator for the protection of healthcare workers who come in direct contact with patients with H1N1. (cdc.gov)
  • Unlike those with achondroplasia or hypochondroplasia, patients with diastrophic dysplasia have epiphyseal involvement and are at risk for degenerative joint disease. (medscape.com)
  • Causes of CNS impairment in patients with CF may include hypoxia, vitamin E or vitamin K deficiency, antibiotic adverse effects, fluid depletion or imbalance, use of psychotropic agents, and stroke from paradoxical emboli. (medscape.com)
  • We focused mainly on the need of postoperative analgesia and possibility to discharge patient to home care after the surgery with the above mentioned type of anaesthesia. (nel.edu)
  • The outbreak involved two patients, both of whom initially were examined for throat pain. (cdc.gov)
  • 3 Next to a laboratory variable (C-reactive protein or erythrocyte sedimentation rate), the DAS28 is composed of weighted values of 28 swollen (SJC) and tender joint counts (TJC) and a patient global assessment. (jrheum.org)
  • Halitosis was found in 3% of healthy controls and 39.5% and 42.9% of patients with gingivitis and periodontitis patients, respectively, making it significantly higher in the gingivitis and periodontitis groups than the healthy controls (p = 0.005). (nature.com)
  • Asymptomatic patients with endometrial cancer had a significantly higher rate of well and moderate-differentiated tumors compared to symptomatic patients (p = 0.008). (biomedcentral.com)
  • Weight gain was similar in both groups with total parenteral nutrition and became significantly higher in patients with simple GS after enteral feeding (p = 0.0046). (bvsalud.org)
  • Initial physical examination of the patient revealed mild scleral icterus, rhabdomyolysis, and rash on his thighs. (cdc.gov)
  • Goals related to the complete helpful results from these trials will be incorporated into control of emesis, ie, no vomiting, include providing care updates of these guidelines. (marysfamilymedicine.org)
  • They have also been advocated for monitoring sedation in intensive care, although the results are controversial. (biomedcentral.com)
  • In some patients, chronic prostacyclin analogue therapy (epoprostenol) can be of benefit, particularly as a bridge to heart-lung transplantation. (medscape.com)
  • In these patients, acute intermittent porphyria appears to have acute exacerbations as well as chronic day-to-day manifestations, and is not just intermittent as its name implies. (springer.com)
  • A periapical survey of a patient in the early mixed dentition is illustrated in Figure 5.1. (trnds.co)
  • The HAL-RAR method for haemorrhoid surgery, introduced as early as in 1995 by Dr. Morigan in Japan. (nel.edu)
  • Patients with nonradicular low back pain underwent a standardized examination and then underwent a standardized spinal manipulation treatment program. (researchgate.net)
  • Shortly after being admitted, the patient experienced acute renal failure, sepsis, pneumonia, and bilateral lower extremity edema, the latter of which was thought to be compartment syndrome. (cdc.gov)
  • Four months after initial assessment, we repeated the syndrome, and 1 had scapular winging and shoulder neurologic examinations, and patients or family members abduction weakness consistent with a long thoracic nerve completed a self-administered questionnaire that gathered paralysis. (cdc.gov)
  • A survey on inappropriate admissions in length of stays and inappropriate admissions inner London found that patients were inap- in Saudi Arabia, and the impending imple- propriately utilizing acute beds because of mentation of a national health insurance difficulties in organizing care at home or system in the country, which would require elsewhere [ 4 ]. (who.int)
  • LV infusion was completed after 24 hours postoperatively in our intensive care unit. (ispub.com)
  • Iron metabolism and immune response to SARS-CoV-2 have not been described yet in intensive care patients, although they are likely involved in Covid-19 pathogenesis. (biomedcentral.com)
  • Hyperferritinemia is constant during intensive care stay: however, its dosage might be helpful in individuating patients developing haemophagocytic lymphohistiocytosis. (biomedcentral.com)
  • The description of iron metabolism and lymphocyte count in Covid-19 patients admitted to the intensive care unit provided with this paper might allow a wider understanding of SARS-CoV-2 pathophysiology. (biomedcentral.com)
  • Their overuse may prolong mechanical ventilation and length of stay in the intensive care unit. (biomedcentral.com)
  • Ideally, sedation in the intensive care unit (ICU) should result in a calm patient who can easily be aroused and has a maintained sleep-wake cycle. (biomedcentral.com)
  • Rampes, et al 2 conducted a thorough review on the reproducibility of patient self-reported joint counts in RA that updates prior reviews. (jrheum.org)
  • ETFs do valuable Patients as they occur the source to their single folder. (sherrimack.com)
  • The herniation is usually in the right periumbilical region, but may occur in some patients on the left underside 6 . (bvsalud.org)
  • Thus, the indications for CBCT - especially in pediatric patients - should be carefully weighed against potential risks.1-6. (trnds.co)
  • The indications for boli of sedative drugs exhibited statistically significant, albeit clinically irrelevant, differences in terms of their association with processed electroencephalographical parameters. (biomedcentral.com)
  • 5 The findings of Rampes, et al 2 confirm that the interobserver reliability of joint counts between patients and HCPs varies between moderate to good, and that the reliability for SJC is lower than for TJC. (jrheum.org)
  • Of 384 patients eligible for one year follow-up (56.3% females, mean (SD) age 45.8 (14.7) years, median (IQR) duration of arthritis 31 (10-62) days), 14.4% were anti-CCP2 positive, and 11.2% were IgM RF positive. (biomedcentral.com)
  • The median length of stay was 33 days, higher in patients with complex GS (56 days). (bvsalud.org)
  • It is not covered for patients with cardiac pacemakers or with metallic clips on vascular aneurysms. (cms.gov)
  • Any intracardiac communication that allows high pulmonary blood flow will lead, over time, to irreversible pulmonary vascular injury, increased pulmonary artery pressures and, ultimately, to right-to-left intracardiac blood flow. (medscape.com)
  • With the shift of postacute care patients from hospitals into skilled nursing units, nursing homes are providing more rehabilitative care (9-11). (cdc.gov)
  • Because of the patient's worsening condition, he was transferred to a tertiary care center. (cdc.gov)