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Pantothenic AcidCoenzyme APantothenate Kinase-Associated NeurodegenerationHydroxybutyratesPeptide SynthasesThermococcusAlaninePhosphotransferases (Alcohol Group Acceptor)PantetheineAlanine Transaminasebeta-AlanineAlanine RacemaseInterleukin-1betaPlumbaginaceaeAcetyl Coenzyme AMolecular Sequence Databeta 2-MicroglobulinAmino Acid SequenceYeast, DriedThiamineAlanine DehydrogenaseKineticsEscherichia coliMutationReceptors, Adrenergic, betaIntegrin beta3PhosphotransferasesHydroxymethyl and Formyl TransferasesHeredodegenerative Disorders, Nervous SystemBase SequenceBinding SitesBiotinTonic PupilTransforming Growth Factor betaAmino AcidsSequence Homology, Amino AcidRecombinant ProteinsLiverMutagenesis, Site-DirectedIsoleucineModels, MolecularAcyl Carrier ProteinCloning, MolecularCell LineLithium ChlorideProtein ConformationSubstrate SpecificityIntegrin alpha5beta1Integrin beta4Acetolactate SynthaseAllosteric RegulationAspartic AcidIntegrin alpha6beta4Cells, CulturedIntegrin beta ChainsPyridoxine
LigaseEnzymeBiosynthesisEscherichiaSynthesisProtein
Ligase3
  • In enzymology, a pantoate-β-alanine ligase (EC 6.3.2.1) is an enzyme that catalyzes the chemical reaction ATP + (R)-pantoate + β-alanine ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + (R)-pantothenate The 3 substrates of this enzyme are ATP, (R)-pantoate, and beta-alanine, whereas its 3 products are AMP, diphosphate, and (R)-pantothenate. (wikipedia.org)
  • The systematic name of this enzyme class is (R)-pantoate:beta-alanine ligase (AMP-forming). (wikipedia.org)
  • Other names in common use include pantothenate synthetase, pantoate activating enzyme, pantoic-activating enzyme, and D-pantoate:beta-alanine ligase (AMP-forming). (wikipedia.org)
Enzyme1
Biosynthesis1
Escherichia2
  • protein_coding" "AAC73733","dacA","Escherichia coli","D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) [Ensembl]. (ntu.edu.sg)
  • We found that the model bacterium Escherichia coli incorporated pyridoxal, niacin, and pantothenate into pyridoxal 5'-phosphate, NAD, and coenzyme A (CoA), respectively. (bvsalud.org)
Synthesis1
  • This pattern was conserved in various bacterial isolates, suggesting a preference for ß-alanine over pantothenate utilization in CoA synthesis. (bvsalud.org)
Protein1
  • Penicillin-binding protein 5, D-alanyl-D-alanine carboxypeptidase [Interproscan]. (ntu.edu.sg)