Subacute Nodular MigratoryMesentericLymphomaLobular panniculitisHistiocytic panniculitisSeptal panniculitisErythema NodosumNodularEquestrian cold panniculitisMigratoryAlpha-1 AntitrypLupusForm of panniculitisSimilar to panniculitisPopsicleManifestationNecrosisInflammationDiagnosisNodulesPancreatic DiseaseSystemicUncommonNeutrophilicInflammatoryPathologyPancreatitisOccurs equallyRarityInfancyCommonlyTypicallySkinAdiposeAugmentation therapyTherapyDescriptorPatientsCold
Subacute Nodular Migratory1
- Vilanova X, Pinol Aguade J. Subacute Nodular Migratory Panniculitis. (medscape.com)
Mesenteric16
- Mesenteric Panniculitis (MP) in CT - A Predictor of Malignancy? (uni-regensburg.de)
- Purpose: The exact etiology of mesenteric panniculitis (MP) is still unknown and has been discussed in relation to different causes. (uni-regensburg.de)
- I thought I would start a discussion for patients with Mesenteric Panniculitis. (mayoclinic.org)
- From what I know, this auto-immune disorder has three stages to it, each with differing names (Mesenteric Panniculitis, Schlerosing Mesenteritis, Retractile Mesenteritis). (mayoclinic.org)
- I was diagnosed with mesenteric panniculitis on February 20 of this year after going to the emergency room in extreme pain and not being able to keep any food or liquid down. (mayoclinic.org)
- I was brought back to the rapid response room from triage because of a high heart rate which i wasn't having any chest pains at all and the e.r. doc sent me for a CT Scan which showed the mesenteric panniculitis. (mayoclinic.org)
- Hello, I have a couple of questions about Mesenteric Panniculitis. (mayoclinic.org)
- when they came back from the CAT scan all the doctor told me I had a very rare disease call mesenteric panniculitis and that she will refer me to a gastrologist I am at work right now but as I'm Walking the Floor I'm getting like cold sweats so I don't know what's going on with this disease. (mayoclinic.org)
- A Mesenteric panniculitis is an uncommon disorder with unknown etiology. (elsevierpure.com)
- We report computed tomography findings of mesenteric panniculitis in an adult patient with renal colic. (elsevierpure.com)
- Canan, A 2016, ' Mimicker of Renal Colic: Mesenteric Panniculitis ', Journal of Nepal Health Research Council , vol. 14, no. 33, pp. 132-134. (elsevierpure.com)
- Mesenteric panniculitis as a possible cause of fever of unknown origin. (bvsalud.org)
- Mesenteric panniculitis is a non-neoplastic condition involving inflammation and fibrosis of the small bowel mesentery . (bvsalud.org)
- The diagnosis of mesenteric panniculitis had been established 2 weeks prior based on an abdominal computerized tomography scan. (bvsalud.org)
- Extensive diagnostic investigations during his hospitalisation were unrevealing, and the symptoms were ultimately attributed to the mesenteric panniculitis . (bvsalud.org)
- This case suggests that mesenteric panniculitis merits consideration in the differential diagnosis of fever of unknown origin . (bvsalud.org)
Lymphoma4
- Manosca F, Ariga R, Bengana C, Reddy VB, Loew J, Gattuso P. Fine-needle aspiration of subcutaneous panniculitis-like T-cell lymphoma. (rush.edu)
- Cyclosporine A as a Primary Treatment for Panniculitis-like T Cell Lymphoma: A Case with a Long-Term Remission. (qxmd.com)
- Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a distinctive cutaneous lymphoma characterized by an infiltration of subcutaneous tissue by neoplastic T cells, similar to panniculitis. (qxmd.com)
- These diseases include mycosis fungoides and subcutaneous panniculitis-like T-cell lymphoma. (dana-farber.org)
Lobular panniculitis4
- citation needed] There are thus four main histological subtypes: lobular panniculitis without vasculitis (acute panniculitis, previously termed Weber-Christian disease, systemic nodular panniculitis) lobular panniculitis with vasculitis septal panniculitis without vasculitis septal panniculitis with vasculitis Erythema induratum, or "Bazin disease", is a panniculitis on the back of the calves. (wikipedia.org)
- Infantile onset panniculitis with uveitis and systemic granulomatosis is a rare granulomatous autoinflammatroy disease characterized by infantile-onset widespread chronic recurrent progressive lobular panniculitis associated with panuveitis arthritis and severe systemic granulomatous inflammation. (globalgenes.org)
- Cytophagic histiocytic panniculitis (CHP) is a rare lobular panniculitis, characterized by subcutaneous proliferation of benign-appearing cytophagic histiocytes and lymphocytes often associated with systemic macrophage activation syndrome (MAS). (biomedcentral.com)
- Skin biopsy specimen revealed a lobular panniculitis with areas of necrosis in both patients. (biomedcentral.com)
Histiocytic panniculitis3
- citation needed] Non-vasculitis forms of panniculitis that may occur include: Cytophagic histiocytic panniculitis was first described in 1980 by Winkelmann as a chronic histiocytic disease of the subcutaneous adipose tissue, which is characterized clinically by tender erythematous nodules, recurrent high fever, malaise, jaundice, organomegaly, serosal effusions, pancytopenia, hepatic dysfunction and coagulation abnormalities. (wikipedia.org)
- Cytophagic histiocytic panniculitis often presents with multiple subcutaneous nodules and eventuates in a bleeding diathesis. (medscape.com)
- Cytophagic histiocytic panniculitis: is it a macrophage activation syndrome in situ? (biomedcentral.com)
Septal panniculitis2
- Erythema nodosum histologically represents the prototype of a septal panniculitis. (dermnetnz.org)
- The classic histopathologic presentation of erythema nodosum is that of a septal panniculitis with a mixed cellular infiltrate of lymphocytes , histiocytes , giant cells , and occasional eosinophils and a characteristic absence of vasculitis (figures 1-3). (dermnetnz.org)
Erythema Nodosum7
- Erythema Nodosum Erythema nodosum is a specific form of panniculitis characterized by tender, red or violet, palpable, subcutaneous nodules on the shins and occasionally other locations. (msdmanuals.com)
- Septal granulomatous panniculitis: comparison of the pathology of erythema nodosum migrans (migratory panniculitis) and chronic erythema nodosum. (medscape.com)
- Is erythema nodosum the same as panniculitis? (handlebar-online.com)
- Erythema nodosum is a type of panniculitis that affects subcutaneous fat in the skin, usually first evident as an outcropping of erythematous nodules that are highly sensitive to touch. (handlebar-online.com)
- Erythema nodosum (EN), is an inflammatory condition characterized by inflammation of the fat cells under the skin, resulting in tender red nodules or lumps that are usually seen on both shins. (handlebar-online.com)
- Erythema nodosum - a review of an uncommon panniculitis. (nih.gov)
- Erythema nodosum is the most common form of panniculitis . (dermnetnz.org)
Nodular2
- Cold panniculitis (CP) is an acute, nodular, erythematous eruption usually limited to areas exposed to the cold. (medscape.com)
- B and C) Nodular panniculitis lesion in legs. (hss.edu)
Equestrian cold panniculitis4
- Equestrian chilblain is also known as equestrian cold panniculitis. (medscape.com)
- Equestrian cold panniculitis in women. (medscape.com)
- Adachi A, Masaki S, Akiyama M. Equestrian cold panniculitis in a cold-storage-room worker. (medscape.com)
- Many patients classified as having cold panniculitis or equestrian cold panniculitis have forms of perniosis that represent dermal vascular injury rather than true panniculitis. (medscape.com)
Migratory2
- Vanegas ES, Cendejas RF, Mondragón A. A 41-year-old woman with migratory panniculitis. (medscape.com)
- These include skin symptoms, such as pancreatic panniculitis, acanthosis nigricans, livedo reticularis, necrolytic migratory erythema, cutaneous signs of hemorrhage, as in persons with severe acute pancreatitis, or the finding of cutaneous metastases of pancreatic carcinoma, which may be a sign of advanced disease. (nih.gov)
Alpha-1 Antitryp5
- Alpha-1 Antitrypsin Deficiency (Alpha-1) can cause panniculitis, an uncommon skin condition. (alpha1.org)
- This characteristic helps to distinguish it from other forms of panniculitis and its association with Alpha-1 Antitrypsin Deficiency. (alphanet.org)
- This realization suggests that the association between Alpha-1 Antitrypsin Deficiency and panniculitis is underdiagnosed in those that have yet to show lung or liver disease. (alphanet.org)
- Recent studies show treatment with the immunosuppressant Anakinra for panniculitis outside of Alpha-1 Antitrypsin Deficiency has proven effective. (alphanet.org)
- The true prevalence of Alpha-1-related panniculitis is still unknown, as diagnosis depends on awareness of the various presentations of diseases related to Alpha-1 Antitrypsin Deficiency, which is lacking even among pulmonologists. (alphanet.org)
Lupus2
- 492 Lupus erythematosus panniculitis, panniculitis associated with lupus erythematosus. (wikipedia.org)
- Juczynska K, Wozniacka A, Waszczykowska E, Zebrowska A. Lupus erythematosus panniculitis resistant to standard treatment, complicated with macrophage activation syndrome. (medscape.com)
Form of panniculitis4
- Microscopically there are epithelioid granulomas and vasculitis in the subcutaneous tissue, making it a form of panniculitis. (wikipedia.org)
- CHP is a rare and often fatal form of panniculitis with multisystem involvement. (wikipedia.org)
- 492 Lipodermatosclerosis is a form of panniculitis associated with chronic venous insufficiency that presents with brown indurations on the front of the shins. (wikipedia.org)
- Other forms include: Subcutaneous fat necrosis of the newborn, a form of panniculitis occurring in newborns that is usually self-resolving, that may be a result of hypoxic injury to relatively high levels of brown fat. (wikipedia.org)
Similar to panniculitis1
- Since several skin conditions can lead to symptoms and signs similar to panniculitis, the diagnosis of panniculitis depends on a positive skin biopsy. (alphanet.org)
Popsicle4
- 491 This condition has been described in children who suck ice or popsicles, and therefore is sometimes referred to as "popsicle panniculitis. (wikipedia.org)
- Popsicle panniculitis in a 5-month-old child on systemic prednisolone therapy. (medscape.com)
- The term 'popsicle' panniculitis, first used by Epstein, 1 describes a benign, cold-induced, subcutaneous fat necrosis of the cheeks in young children who suck on the frozen confection. (contemporarypediatrics.com)
- Popsicle panniculitis. (contemporarypediatrics.com)
Manifestation4
- Deleersnijder D, Betrains A, De Haes P, Peperstraete L, Buelens J, Blockmans D. Panniculitis as the first clinical manifestation of MPO-positive ANCA-associated vasculitis. (medscape.com)
- Panniculitis can be the initial manifestation of both benign and malignant conditions, presenting with or without arthritis. (hss.edu)
- Recognizing that panniculitis is an Alpha-1 manifestation is crucial to managing accessibility to effective therapies. (alphanet.org)
- Andrade R, Camacho CP, Manso AC & Sérgio M. (2021) Pancreatic Panniculitis: A Rare Manifestation of Pancreatic Disease. (scitcentral.com)
Necrosis6
- 494 Pancreatic panniculitis (also known as enzymatic panniculitis, Pancreatic fat necrosis, and subcutaneous fat necrosis) is a panniculitis most commonly associated with pancreatic carcinoma, and more rarely with anatomic pancreatic abnormalities, pseudocysts, or drug-induced pancreatitis. (wikipedia.org)
- Cold panniculitis needs to be distinguished from other disorders such as adiponecrosis subcutanea ( subcutaneous fat necrosis of the newborn , cold panniculitis of the newborn) and sclerema neonatorum . (medscape.com)
- In cold panniculitis of the newborn (adiponecrosis subcutanea), cold injury in the full-term newborn may occur with focal fat necrosis and a granulomatous and fibrous panniculitis in which the infiltrate usually contains multifocal histiocyte foreign body giant cells containing bifringent star-shaped crystals. (medscape.com)
- The pathophysiology of the panniculitis and arthritis is related to hyperlipasemia, in which lipase and other proteases are released into the bloodstream, causing adipose tissue necrosis and skin lesions. (hss.edu)
- Pancreatitis, panniculitis, and polyarthritis (PPP) syndrome: MRI features of intraosseous fat necrosis involving the feet and knees. (hss.edu)
- Fist described in 1883 by Chiari [1], Pancreatic panniculitis (PP), also known as pancreatic fat necrosis and enzymatic panniculitis, is a rare necrosis of subcutaneous adipocytes triggered by inflammatory, traumatic or malignant pancreatic disease. (scitcentral.com)
Inflammation7
- Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin - panniculus adiposus). (wikipedia.org)
- In cold panniculitis, localized cold damage leads to inflammation of the subcutaneous adipose tissue and is particularly likely to occur in patients with chilblains or in paralyzed limbs affected by poliomyelitis. (medscape.com)
- Panniculitis is an aggravation of the fatty layer underneath the skin which occurs due to Crohn's disease (inflammation of the digestive system) or ulcerative colitis (inflammation of the colon and rectum). (news-medical.net)
- Panniculitis describes inflammation of the subcutaneous fat that can result from multiple causes. (msdmanuals.com)
- Panniculitis can be classified as lobular or septal depending on the principal site of the inflammation within the fat. (msdmanuals.com)
- Signs of systemic inflammation, such as fever and malaise, can accompany panniculitis. (msdmanuals.com)
- The excessive inflammation that results causes fever, diarrhea, panniculitis, and the other signs and symptoms of otulipenia. (medlineplus.gov)
Diagnosis7
- Differential diagnosis also includes poststeroid panniculitis and frostbite. (medscape.com)
- Cold panniculitis is a rare disorder in which the diagnosis probably is hampered by overlapping terminology. (medscape.com)
- A diagnosis was made of pancreatitis, panniculitis, and polyarthritis (PPP) syndrome, with a presumed pancreatic malignancy. (hss.edu)
- The workup for a panniculitis diagnosis recommends Alpha-1 testing, but because there is no diagnostic algorithm endorsed by any dermatological society, it is hard to know the true prevalence. (alphanet.org)
- The median age of diagnosis for panniculitis associated with the Alpha-1 ZZ-genotype is around 36 years. (alphanet.org)
- Diagnosis of panniculitis is by usually by clinical appearance and can be confirmed by biopsy. (msdmanuals.com)
- Rose C, Leverkus M, Fleischer M, Shimanovich I. Histopathology of panniculitis - aspects of biopsy techniques and difficulties in diagnosis. (medscape.com)
Nodules2
- Panniculitis is characterized by tender and erythematous subcutaneous nodules located over the extremities and sometimes over the posterior thorax, abdominal area, breasts, face, or buttocks. (msdmanuals.com)
- Diagnose panniculitis by clinical evaluation (including presence of tender, red, subcutaneous nodules) and confirm with excisional or incisional biopsy. (msdmanuals.com)
Pancreatic Disease2
- Pancreatic disease, panniculitis, polyarthrtitis syndrome successfully treated with total pancreatectomy: Case report and literature review. (hss.edu)
- Pancreatic panniculitis is a very rare complication associated with pancreatic disease, appearing in approximately 2 to 3% of all patients, most commonly those with acute or chronic pancreatitis, but also in patients with pancreatic carcinoma. (scitcentral.com)
Systemic3
- Panniculitis can also be classified based on the presence or absence of systemic symptoms. (wikipedia.org)
- Panniculitis without systemic disease can be a result of trauma or cold. (wikipedia.org)
- Newly diagnosed with Infantile onset panniculitis with uveitis and systemic granulomatosis? (globalgenes.org)
Uncommon2
- Panniculitis is an uncommon skin condition. (alpha1.org)
- Erythema induratum (EI) is an uncommon inflammatory disorder with alterations centered upon the subcutaneous fat tissue (panniculitis). (handlebar-online.com)
Neutrophilic1
- Young TK, Gutierrez D, Meehan SA, Pellett Madan R, Oza VS. Neutrophilic panniculitis arising from hematogenous spread of methicillin-resistant Staphylococcus aureus. (medscape.com)
Inflammatory3
- Restated, an inflammatory disorder primarily localized in the subcutaneous fat is termed a "panniculitis", a group of disorders that may be challenging both for the clinician and the dermatopathologist. (wikipedia.org)
- Panniculitis is an umbrella term for a group of different inflammatory conditions found in the subcutaneous fat of the skin - and a rare result for ZZ individuals and other severely deficient phenotypes. (alphanet.org)
- Treat panniculitis supportively and consider anti-inflammatory or immunosuppressive drug therapy, particularly if manifestations are severe. (msdmanuals.com)
Pathology1
- Pathology shows a septal necrotizing panniculitis with neutrophil infiltration. (hss.edu)
Pancreatitis1
- However, lipase levels are not the only factor implicated, as the relative frequency of pancreatitis with high serum lipase levels contrasts with the rarity of pancreatic panniculitis, and there are some PP cases in the literature that have been described with normal serum levels of all pancreatic enzymes [3], supporting the likely involvement of other unidentified factors in the causality of this entity. (scitcentral.com)
Occurs equally2
- Panniculitis occurs equally among men and women, usually developing at an average age of 40. (alpha1.org)
- Panniculitis occurs equally in men and women. (alphanet.org)
Rarity1
- The rarity of Alpha-1-related panniculitis means a lack of affordable and effective therapies. (alphanet.org)
Infancy1
- Cold panniculitis occurs during infancy and childhood and in adult women who are obese. (medscape.com)
Commonly1
- Adult women who are obese most commonly have cold panniculitis. (medscape.com)
Typically1
- A panniculitis outbreak is typically gradual. (alphanet.org)
Skin5
- Traumatic panniculitis is a panniculitis that occurs following trauma to the skin. (wikipedia.org)
- Panniculitis causes painful, raised red bumps to form on the skin. (alpha1.org)
- Panniculitis sometimes turns into deep ulcers in the skin where the tissue breaks down. (alpha1.org)
- Panniculitis spots sometimes develop after some kind of trauma or injury to the skin that would be minor in most people, such as vigorous exercise, intravenous injections, or cryosurgery (surgery that involves freezing the skin). (alpha1.org)
- But when the spots become deep ulcers in the skin with tissue breakdown it is known as necrotizing panniculitis. (alphanet.org)
Adipose1
- Cold panniculitis results from a cold injury to adipose tissue. (medscape.com)
Augmentation therapy2
- People with Alpha-1 who have panniculitis are sometimes treated with augmentation therapy. (alpha1.org)
- Antibiotics, chemotherapeutic agents, and Dapsone have also displayed varying levels of effectiveness in non-Alpha-1 panniculitis, so they may have some efficacy if augmentation therapy is not available. (alphanet.org)
Therapy3
- Cold Panniculitis After Ice Therapy for Supraventricular Tachycardia. (medscape.com)
- Cold Panniculitis Following Ice Therapy for Cardiac Arrhythmia. (medscape.com)
- The evidence for efficacy of this therapy in Alpha-1-related panniculitis is not strong, but it may be an alternative. (alphanet.org)
Descriptor1
- Panniculitis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
Patients3
- Patients with pancreatic malignancy and panniculitis (either with or without arthritis) seem to have a shorter median survival time than patients without this presentation [3]. (hss.edu)
- Il s'agit d'une étude transversale, monocentrique et descriptive, durant 12 mois, incluant les patients âgés d'au moins 18 ans admis en réanimation polyvalente pour un sepsis ou choc septique. (bvsalud.org)
- Cette étude documentaire, analyse les données des patients diagnostiqués et traités pour tuberculose de 2007 à 2017 en RDC. (bvsalud.org)
Cold6
- 492 Cold panniculitis is a panniculitis occurring after exposure to cold, most often seen in infants and young children. (wikipedia.org)
- Cold panniculitis: Adverse cutaneous effect of whole-body cryotherapy. (medscape.com)
- Quesada-Cortes A, Campos-Munoz L, Diaz-Diaz RM, Casado-Jimenez M. Cold panniculitis. (medscape.com)
- [ 4 ] Some overlap occurs, and cold panniculitis of the newborn has been associated with ice pack application. (medscape.com)
- Cold panniculitis is caused by cold injury in children and in women who are obese. (medscape.com)
- Ter Poorten JC, Hebert AA, Ilkiw R. Cold panniculitis in a neonate. (contemporarypediatrics.com)