Pancreaticoduodenectomy pancreatic fistula. Medical search. Frequent questions

Context Pancreaticoduodenectomy (PD) is still characterized by high morbidity rates even in high volume centers, mainly represented by postoperative pancreatic fistula (POPF) and its associated further consequences. (unina.it)
Wirsung diameter and pancreatic texture are well known features related to increased POPF risk. (unina.it)
However, limited information about the relationship between morphological features of pancreatic stump and POPF onset is available. (unina.it)
Objective Aim of the study was to evaluate the relationship between pancreatic stump morphology, intra-operatively assessed, and the occurrence of POPF in patients undergoing PD in an high volume center. (unina.it)
In multivariate analysis, only pancreatic stump soft texture and Wirsung diameter smaller than 4 mm were associated with POPF. (unina.it)
Conclusion This study confirms small Wirsung diameter and soft pancreatic texture as the main determinants for POPF development. (unina.it)
The effect of preoperative biliary drainage (PBD) prior to pancreaticoduodenectomy (PD) on postoperative pancreatic fistula (POPF) is variably reported in literature. (thieme-connect.de)
Why should biliary or pancreatic stenting affect the incidence of POPF? (thieme-connect.de)
Clinically relevant postoperative pancreatic fistula (CR-POPF) is a life-threatening complication following pancreaticoduodenectomy (PD). (hunimed.eu)
One of the most important life-threatening complications is a postoperative pancreatic fistula (POPF) [ 4 , 5 ]. (kjco.org)
The secondary outcomes include postoperative major complications (Clavien-Dindo≥3), postoperative pancreatic fistula (POPF), post-pancreatectomy acute pancreatitis (PPAP), infection, and unexpected relaparotomy, as well as postoperative length of stay, 30-day mortality, and 90-day mortality. (biomedcentral.com)
The main postoperative complications include postoperative pancreatic fistula (POPF), post-pancreatectomy hemorrhage (PPH), and delayed gastric emptying (DGE). (biomedcentral.com)
No technique showed a superiority over the others in terms of post-operative pancreatic fistula formation (POPF) in open neither during a minimally invasive approach. (sgo-iasgo.com)
Our aim was to perform a review, including only randomized controlled trial meta-analyses or well-designed studies, of evidence regarding the correlation between EN and main complications and outcomes after pancreaticoduodenectomy, as delayed gastric emptying (DGE), postoperative pancreatic fistula (POPF), postpancreatectomy hemorrhage (PPH), length of stay and infectious complications. (unipa.it)
EN appeared safe and tolerated for patients after PD, even if it did not reveal any advantages in terms of POPF, PPH, length of stay and infectious complications. (unipa.it)
Background: Following pancreatic resection, postoperative pancreatic fistula (POPF) is still the leading cause of significant morbidity and death. (surgchronicles.gr)
Operative time and hospital stay were slightly increased in the external group while the postoperative pancreatic fistula (POPF) was slightly increased in the internal group. (surgchronicles.gr)
Postoperative pancreas fistula (POPF) is a major complication after total gastrectomy with splenectomy. (biomedcentral.com)
This study was designed to evaluate the effects of abdominal shape at the umbilicus and the upper abdomen on short-term surgical outcomes, particularly the incidence of postoperative pancreas fistula (POPF) in patients undergoing total gastrectomy with splenectomy. (biomedcentral.com)

Tumor recurrence is independent of pancreatic fistula in patients after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma. (bvsalud.org)
The purpose of our study was to determine if a relationship exists between PF and tumor recurrence (both peritoneal and local) in patients after PD for pancreatic ductal adenocarcinoma . (bvsalud.org)
Pancreaticoduodenectomy Among Patients With Pancreatic Ductal Adenocarcinoma. (cancercentrum.se)
Impact of intensified chemotherapy in metastatic pancreatic ductal adenocarcinoma (PDAC) in clinical routine in Europe. (cancercentrum.se)

Results: Two hundred eleven patients underwent pancreaticoduodenectomy with pancreatic-enteric anastomosis, received appropriate saline/octreotide doses, and were available for endpoint analysis. (arizona.edu)
The two groups were comparable with respect to demographics (54% male, median age 66 years), type of pancreaticoduodenal resection (60% pylorus-preserving), type of pancreatic-enteric anastomosis (87% end-to-side pancreaticojejunostomy), and pathologic diagnosis. (arizona.edu)
Moreover, an higher risk of failure of pancreatic anastomosis is also observed in large pancreatic stumps and when main pancreatic duct is centrally located. (unina.it)
We need more such studies from other centers to confirm that the rare event of preoperative biliary and pancreatic stenting has indeed this harmful effect on healing of postoperative pancreatic anastomosis. (thieme-connect.de)
Although innumerable details of pancreaticoduodenectomy yield to continued innovation, a comprehensive discussion of intraoperative variants (ie, duct to mucosa vs invagination of the pancreaticojejunal anastomosis, diverse approaches to vein resection and reconstructions, nuances of each enteric anastomosis, and modifications of Roux-en-Y reconstructions, to name a few) is beyond the scope of this article. (medscape.com)
To investigate the simplicity, reliability, and safety of the application of single-layer mucosa-to-mucosa pancreaticojejunal anastomosis in pancreaticoduodenectomy. (wjgnet.com)
Re-enforce this by suturing the capsule of the pancreas to the serosa of the jejunum around the pancreatic anastomosis. (msurgery.ie)
Despite significant improvements in the safety and efficacy of pancreatic surgery, pancreaticoenteric anastomosis continues to be the "Achilles heel" of pancreaticoduodenectomy, due to its association with a measurable risk of leakage or failure of healing, leading to pancreatic fistula. (sagepub.com)
Pancreatic-enteric anastomosis has remained a true Achilles' heel in this complex and technically demanding operation. (biomedcentral.com)

Recurrence of pancreatic adenocarcinoma after pancreaticoduodenectomy (PD) can be increased in patients with pancreatic fistula (PF). (bvsalud.org)
Results Sixty-two patients underwent biliary stenting alone, 5 patients underwent both biliary and pancreatic stenting, and 237 patients were not stented in the adenocarcinoma group without chronic pancreatitis. (thieme-connect.de)
Prognostic indicators for survival after resection of pancreatic adenocarcinoma. (medigraphic.com)
Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma. (edu.pl)
Longterm survival after pancreatoduodenectomy for pancreatic adenocarcinoma: is cure possible? (edu.pl)

Management of early hemorrhage from pancreatic anastomoses after pancreaticoduodenectomy. (edu.pl)
Results of the Monte Carlo simulation determined: the incidence of postoperative pancreatic fistula in the Hemopatch® group reported was 7.7% vs 30.9% (p value: 0.05), biliary fistula 7.7% vs 15.4% (p value: 0.05), hemorrhage 7.7% vs 15.5% (p value: 0.05), mean stay 20.8 vs 26.3 days (p value: 0.01), ICU stay 7.1 vs 9.1 days (p value: 0.01). (blogspot.com)
An attempt was made to evalu- ate the effectiveness of argon plasma coagulation to stop late intraluminal postpancreatectomy hemorrhage in patients after pancreaticoduodenectomy and pancreaticogastrostomy at the reconstructive stage. (surgchronicles.gr)

in a subgroup composed by 72 cases we realized a prospective study recording intra-operative measurements of the remnant pancreatic stump, recording surgeon's judgment about pancreatic texture, and highlighting the caliber of main pancreatic duct, its position and the whole area. (unina.it)
Between March 2011 and June 2012, in a consecutive series of 72 PD, we prospectively recorded the following characteristics of the pancreatic stump: surgeon's judgment about pancreatic texture, diameter of main pancreatic duct, the whole area of pancreatic section (approximately calculated as elliptic), the distance between Wirsung duct and cranio-caudal and antero-posterior margins. (unina.it)
and pancreatic duct disruption based on the results of thin-cut computed tomography or endoscopic retrograde cholangiopancreatography (ERCP). (wikipedia.org)
The pancreatic organ injury scale, as minimally modified, is: When there is no pancreatic duct injury, typically hemostasis and surgical drainage are the main form of treatment. (wikipedia.org)
Methods Retrospective single center cohort study of patients who underwent pancreaticoduodenectomy over the past 10 years for carcinoma obstructing the lower common bile duct. (thieme-connect.de)
Stent placement can not only induce pancreatic and bile duct wall inflammation but also introduce infection into the biliopancreatic system, and this may be responsible. (thieme-connect.de)
Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial. (medigraphic.com)
In 1946, Waugh and Clagett described a formal en-bloc resection of the gallbladder with the common bile duct (CBD), gastric antrum, duodenum, and pancreatic head performed as a one-stage procedure, which we recognize today as the classic pancreaticoduodenectomy. (medscape.com)
Next, anastomose the cut end of the pancreatic duct to the kekunum lower down. (msurgery.ie)
Dr. Kimberly Kirkwood specializes in the treatment of pancreatic cancer as well as tumors of the stomach, spleen, gallbladder, bile duct and gastrointestinal tract. (ucsf.edu)
Pancreaticoduodenectomy (PD) nowadays serves as a standard treatment for patients with disorders of the pancreas, intestine, and bile duct. (biomedcentral.com)
Pancreaticoduodenectomy (PD)-also known as a Whipple procedure-is a complex operation that is used to treat tumors and other disorders of the pancreas, intestine, and bile duct. (biomedcentral.com)
External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trial. (edu.pl)
A retrospective observational data review (26 consecutive pancreaticoduodenectomies) from July 2015 to October 2016 using the same surgical technique, 13 procedures reinforcing the duct-to-mucosa pancreaticojejunostomy with Hemopatch® and 13 procedures without Hemopatch® at Miguel Servet University Hospital, Zaragoza, Spain. (blogspot.com)
the internal drainage group: the pancreatic duct was drained into the intestinal lumen, and the external drainage group: the pancreatic duct was drained through the anterior abdominal wall. (surgchronicles.gr)
[ 3 ] Surgery is indicated for pain, pseudocysts , suspicion of malignancy, stenosis of the mid to distal pancreatic duct, pancreatolithiasis, and stenosis of the celiac or mesenteric vessels. (medscape.com)
The ventral bud rotates dorsally and fuses with the dorsal bud, and the duct of the distal part (body and tail) of the dorsal bud unites with the duct of the ventral bud to form the main pancreatic duct (of Wirsung). (medscape.com)
Because the common bile duct (CBD) also arises from the ventral bud, it forms a common channel with the main pancreatic duct. (medscape.com)
The remaining proximal part (head) of the duct of the dorsal bud remains as the accessory pancreatic duct (of Santorini). (medscape.com)
The lower (terminal) part of the CBD runs behind (or sometimes through) the upper half of the head of pancreas before it joins the main pancreatic duct (MPD) to form a common channel (ampulla). (medscape.com)
The normal pancreatic duct may be just seen in the head (3-4 mm) and proximal body (2-3 mm) of the pancreas on CT scan. (medscape.com)

Conclusions: These data demonstrate that the prophylactic use of perioperative octreotide does not reduce the incidence of pancreatic fistula or total complications after pancreaticoduodenectomy. (arizona.edu)
Patients who underwent biliary stenting alone, biliary and pancreatic stenting, and no stenting prior to pancreaticoduodenectomy were the three study cohort groups and their records were scrutinized for the incidence of postoperative pancreatic fistula. (thieme-connect.de)
Incidence of pancreatic fistula, and occurrence of Clavien grade I/II and grade III/IV complications were comparable between groups. (sages.org)
However, to the best of our knowledge, no systematic reviews or meta-analytic studies have assessed the incidence and risk factors of POAP after pancreaticoduodenectomy (PD). (figshare.com)

We will focus on the technical aspects and perioperative impacts of the Traverso modification of pancreaticoduodenectomy. (medscape.com)
Patients who have undergone pancreaticoduodenectomy often present perioperative malnutrition that is worse in the early postoperative days, affects the process of healing, the intestinal barrier function and the number of postoperative complications. (unipa.it)
There Is No Increase in Perioperative Mortality After Pancreaticoduodenectomy in Octogenarians: Results From the Swedish National Registry for Tumors in the Pancreatic and Periampullary Region. (cancercentrum.se)

Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. (medigraphic.com)
The aim of this study was to share early outcomes of the first pancreaticoduodenectomy operations performed by our surgery team after completing a gastroenterological surgery and surgical oncology fellowship program. (bibliomed.org)
Conclusion: Our experience demonstrates that pancreaticoduodenectomy can be performed with acceptable outcomes after fellowship training that includes pancreatic surgery. (bibliomed.org)
Her NIH-funded research focuses on pancreatic inflammatory pain and on the many factors which may improve outcomes for patients following resection of pancreatic tumors. (ucsf.edu)
She focuses on improving outcomes for patients after pancreas surgery and on understanding how pancreatic cancer develops at a cellular level. (ucsf.edu)
The use of Hemopatch® as a sealant may result in better clinical (less morbidity) and possibly economic outcomes in pancreaticoduodenectomy. (blogspot.com)
Risk factors and outcomes for patients with pancreatic cancer undergoing surgical exploration without resection due to metastatic disease: A national cohort study. (cancercentrum.se)
Nationwide trends and outcomes of neoadjuvant chemotherapy in pancreatic cancer - an analysis of the Swedish national pancreatic cancer registry. (cancercentrum.se)

The artery first approach for resection of pancreatic head cancer. (medigraphic.com)
A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. (edu.pl)

See also Ampullary Carcinoma , Pancreatic Cancer , Pancreatic Trauma , and Carcinoma of the Ampulla of Vater . (medscape.com)
ASO Visual Abstract: Hospital Designations and Their Impact on Guideline-Concordant Care and Survival in Pancreatic Cancer: Do They Matter? (elsevierpure.com)
Risk factors of pancreatic fistula following pancreaticoduodenectomy for periampullary cancer. (krakow.pl)
Dr. Kirkwood specializes in treating pancreatic cancer as well as tumors of the upper gastrointestinal tract. (ucsf.edu)
Hariharan D, Saied A, Kocher HM: Analysis of mortality rates for pancreatic cancer across the world. (edu.pl)
Systematic review and meta-analysis of standard and extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer. (edu.pl)
Background: Metal stents for unresectable pancreatic cancer are associated with longer patency and superior cost-effectiveness. (scirp.org)
Conclusion: Biliary bypass surgery for unresectable pancreatic cancer may improve patient survival, although prolongs hospital stay. (scirp.org)
Pancreatic cancer is one of the leading causes of cancer related mortality all over the world. (scirp.org)
Thus, palliative managements are the sole treatment options for about 80% of pancreatic cancer patients. (scirp.org)
High resection rate improves overall survival in elderly patients with pancreatic head cancer - A cohort study. (cancercentrum.se)
First results from the Swedish National Pancreatic and Periampullary Cancer Registry. (cancercentrum.se)

Aim: In this study, we aimed to determine the clinical value and prognostic significance of neutrophil / lymphocyte ratio in predicting pancreatic fistula in patients who underwent pancreatoduodenectomy due to periampullary tumor.Material and Methods: Patients who underwent pancreatoduodenectomy for periampullary tumor between 2010-2019 were included in the study. (annalsmedres.org)
The pancreatic fistula rate was similar in the patients who underwent biliary stenting alone when compared with the group which was not stented. (thieme-connect.de)
However, the patients who underwent both biliary and pancreatic stenting had a significant increase in postoperative pancreatic fistula compared with the not stented ( p = 0.003). (thieme-connect.de)
A total of 100 preoperative high-quality CT scans of consecutive patients who underwent pancreaticoduodenectomy in our institution between 2011 and 2019 were analyzed. (hunimed.eu)
Between September 2003 and December 2013, 405 patients underwent elective pancreaticoduodenectomy or pylorus preserving pancreaticoduodenectomy for periampullary malignancy. (kjco.org)
Material and Methods: Patients who underwent pancreaticoduodenectomy by the same surgical team between November 2015 and August 2018 were retrospectively analyzed. (bibliomed.org)

The diagnoses of pancreatic fistula and clinically relevant pancreatic fistula after pancreaticoduodenectomy were judged strictly by the International Study Group on pancreatic fistula definition. (wjgnet.com)

Several studies reported leukocytosis on postoperative day (POD) 4 or 5 is related with pancreatic anastomotic leakage after PD [ 13 ]. (kjco.org)
Include haemorrhage, anastomotic leak & pancreatic fistula formation. (msurgery.ie)
Pancreatic Anastomotic Leak Study Group. (edu.pl)
Pancreatic anastomotic leakage after pancreaticoduodenectomy in 1,507 patients: a report from the Pancreatic Anastomotic Leak Study Group. (edu.pl)

A pancreatic injury is some form of trauma sustained by the pancreas. (wikipedia.org)
Abstract Resection of pancreas, in particular pancreaticoduodenectomy, is a complex procedure, commonly performed in appropriately selected patients with benign and malignant disease of the pancreas and periampullary region. (sagepub.com)
1. Introduction Pancreaticoduodenectomy (PD) is one of the standard treatments for various benign and malignant disease of the pancreatic head and periampullary region and distal pancreatectomy for lesions in the tail of pancreas. (sagepub.com)
The acute inflammatory response of the residual pancreas may affect the healing of pancreatoenteric anastomoses, leading to postoperative pancreatic fistulas (POPFs), abdominal infections, and even progressive systemic reactions, conditions that negatively affect patients' prognoses and can cause death. (figshare.com)
The pancreatic neck is the arbitrary junction between the head and body of the pancreas. (medscape.com)
Adenocarcinomas of the distal pancreas account for 15-25% of pancreatic adenocarcinomas . (medscape.com)
Because the pancreas lies obliquely, all parts of the pancreas are not at the same transverse level and are not seen in 1 section (cut) of the CT scan-the pancreatic head is lower (at the level of L2) than its body (L1) and tail (T12). (medscape.com)

Does prophylactic octreotide decrease the rates of pancreatic fistula and other complications after pancreaticoduodenectomy? (arizona.edu)
Dive into the research topics of 'Does prophylactic octreotide decrease the rates of pancreatic fistula and other complications after pancreaticoduodenectomy? (arizona.edu)

The New Fully Automated System For Ki67 Evaluation in Pancreatic Neuroendocrine Tumors (PNETs). (unina.it)
Spleen-preserving distal pancreatectomy is reserved for chronic pancreatitis , proven benign pancreatic lesions and cysts, neuroendocrine tumors, and trauma . (medscape.com)
Neuroendocrine tumors represent 2-4% of pancreatic tumors. (medscape.com)
These tumors represent 0.9-2.5% of solid pancreatic tumors, with 82-93% of cases diagnosed in young women. (medscape.com)
Serous cystadenomas are typically benign and represent 20-40% of cystic pancreatic tumors. (medscape.com)
Because of their similarities in appearance on diagnostic imaging, pancreatic pseudocysts and cystic tumors may be distinguished by endoscopic ultrasonography with fine-needle aspiration. (medscape.com)

Jianhua Yu, L. Wu and B. Li, Meta-analysis of pancreaticogastrostomy versus pancreaticojejunostomy on occurrences of postoperative pancreatic fistula after pancreaticoduodenectomy, Asian Journal of Surgery (2015). (scipedia.com)
Cristina Ridolfi Pancreatic Surgery Division, IRCCS "Humanitas" Clinical Institute. (unina.it)
Pancreatic injuries are classified according to the criteria of the American Association for the Surgery of Trauma (AAST). (wikipedia.org)
Pancreatic trauma can be a result of blunt trauma, abdominal or retroperitoneal surgery, or endoscopic retrograde cholangiopancreatography (ERCP). (medscape.com)
Despite advances in minimally invasive surgery, the implementation of total laparoscopic pancreaticoduodenectomy (TLPD) remains controversial. (sages.org)
Pancreatic surgery is challenging and associated with high morbidity. (kjco.org)
Hepatobiliary & Pancreatic Surgery » Meet the Team » Gastrointestinal Surgery » Kimberly Kirkwood, M.D. (ucsf.edu)
Dr. Kirkwood earned a medical degree at the University of Pennsylvania and completed a surgical residency and a fellowship in advanced general surgery with a focus on pancreatic surgery at Massachusetts General Hospital. (ucsf.edu)
As pancreaticoduodenectomy (PD) is one of the greatest challenges in gastrointestinal surgery, the current study aimed to evaluate either internal or external drainage is the best technique for preventing pancreatic fistula (PF) following pancreaticoduodenectomy (PD). (surgchronicles.gr)
The subgroup results of the meta-analysis by different POAP diagnostic criteria showed that the incidences of POAP were 15% (95% CI, 5-38) in the International Study Group for Pancreatic Surgery group, 51% (95% CI, 42-60) in the Connor group, 7% (95% CI, 2-24) in the Atlanta group, and 5% (95% CI, 2-14) in the unclear group. (figshare.com)
Pancreatic Surgery 3. (researchgate.net)
Global Audits on Pancreatic Surgery Group (GAPASURG). (cancercentrum.se)

ASO Visual Abstract: A Machine-Learning Approach to Predict Postoperative Pancreatic Fistula after Pancreaticoduodenectomy Using only Preoperatively Known Data. (ucsf.edu)

Few studies focus on the relation between enteral nutrition (EN) and postoperative complications. (unipa.it)

In 1937, Brunschwig extended the indications for pancreaticoduodenectomy by performing the operation for pancreatic head lesions. (medscape.com)
However, with the increasing use of imaging studies, more incidental pancreatic lesions are discovered and diagnosed. (medscape.com)

Improvement of delayed gastric emptying in pylorus-preserving pancreaticoduodenectomy: results of a prospective, randomized, controlled trial. (edu.pl)

After the demanding resection, pancreatic-enteric, biliary-enteric, and gastrojejunal anastomoses are required to complete digestive tract reconstruction. (biomedcentral.com)
Several anastomoses have been described for the reconstruction of the pancreatic stump after pancreaticoduodenectomy. (sgo-iasgo.com)

Being a woman [OR (1.37, 95% CI, 1.06-1.77)] or having a soft pancreatic texture [OR (2.56, 95% CI, 1.70-3.86)] were risk factors of POAP after PD. (figshare.com)

Pancreatic fistula (PF) is the most common and challenging complication after pancreaticoduodenectomy (PD). (scipedia.com)
1 Pancreatic fistula (PF) is the most devastating postoperative complication occurring in 2.5-25% patients, 2 and has become the main reason for increased morbidity and mortality, prolonged length of hospital stay, and increased medical costs. (scipedia.com)
Each trial reported significant decreases in overall complication rates, and two of the four reported significantly lowered rates of pancreatic fistula in patients receiving prophylactic octreotide. (arizona.edu)

Aim: Pancreaticoduodenectomy is a challenging procedure used primarily for the treatment of pancreatic head cancers. (bibliomed.org)

A systematic review and meta-analysis of pyloruspreserving versus classical pancreaticoduodenectomy for surgical treatment of periampullary and pancreatic carcinoma. (edu.pl)
All patients presented with obstructive jaundice due to pancreatic head carcinoma and treated in University Hospital Hassan II, Fez, Morocco, from January 2013 to November 2016 were enrolled in this study. (scirp.org)

Results Pancreatic fistula occurred in 19 cases (23.8%), 10 of them clinically significant (grade B and C according to ISGPF classification). (unina.it)
Postcreaticoduodenectomy operative pancreatic fistula: an international study group (ISGPF) definition. (medigraphic.com)
Liang TB, Bai XL, Zheng SS Pancreatic fistula after pancreaticoduodenectomy: diagnosed according to International Study Group Pancreatic Fistula (ISGPF) definition. (edu.pl)

Surgical Management of Hepatobiliary and Pancreatic Disorders (Second ed.). doi:10.3109/9781841847603. (wikipedia.org)
Pancreatic-protocol computed tomography (CT) with thin collimation will detect anatomic contraindications for surgical resection. (medscape.com)
A retrospective analysis was performed on the data of patients who received pancreaticoduodenectomy completed by the same surgical group between January 2011 and April 2014 in the General Hospital of the People's Liberation Army. (wjgnet.com)
Pancreaticoduodenectomy (PD) or Pylorus preserving pancreaticoduodenectomy (PPPD) are technically challenging surgical procedures that require a certain high level of experience and techniques with regard to resection and reconstruction [ 1 ]. (kjco.org)
Surgical procedures such as total gastrectomy with splenectomy should be very carefully executed in obese patients or patients with a deep abdominal cavity to decrease the risk of postoperative pancreatic fistula. (biomedcentral.com)
Surgical exploration without resection in pancreatic and periampullary tumours: report from a national database. (cancercentrum.se)

One thousand consecutive pancreaticoduodenectomies. (medigraphic.com)

Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy. (edu.pl)
Pancreatosplenectomy (pancreaticosplenectomy) or spleen-preserving pancreatectomy is performed to surgically treat pancreatic disease of the tail and body. (medscape.com)
Symptomatic or enlarging pancreatic pseudocysts can be treated with distal pancreatectomy after the acute pancreatitis episode has resolved. (medscape.com)

one retrospective case review found that computed tomography had either failed to find injuries or had underestimated the severity of injury in more than half of 17 pancreatic injury patients. (wikipedia.org)

LAPD combines the superior ergonomics and visualization of open pancreaticoduodenectomy (OPD) with the benefits of a minimally invasive approach. (sages.org)
Background: Reports on the safety of minimally invasive pancreaticoduodenectomy compared to open pancreaticoduodenectomy (OPD) have demonstrated mixed results. (psu.edu)

One study comparing robotic pancreaticoduodenectomy (RPD) vs OPD demonstrated decreased complications associated with RPD. (psu.edu)

The single most significant cause of morbidity and mortality after PD is the development of pancreatic leak and fistula. (sagepub.com)
To determine the efficacy and the impact on postoperative morbidity, mortality, and direct hospitalization costs of using the hemostatic-sealant Hemopatch® in patients undergoing pancreaticoduodenectomy. (blogspot.com)

Most of these complications are related to pancreatic fistula, with serious complications of intra-abdominal abscess, postoperative bleeding, and multiorgan failure. (sagepub.com)

Pancreaticoduodenectomy with early superior mesenteric artery dissection. (medigraphic.com)

After PD, pancreatic continuity can be restored by performing either a pancreaticojejunostomy (PJ) or a pancreaticogastrostomy (PG). (scipedia.com)

Management of a pancreatic injury can be difficult because other abdominal organs, such as the liver, usually have sustained trauma as well. (wikipedia.org)

All patients were operated on with curative intent for suspected pancreatic malignancy by a single experienced pancreatic surgeon. (sages.org)

The modern colloquial name for this operation (ie, Whipple procedure) refers to Dr Allen Oldfather Whipple, the surgeon who reported his series of pancreaticoduodenectomies in 1935. (medscape.com)

Background Surgeons and endoscopists welcome routine preoperative biliary drainage prior to pancreaticoduodenectomy despite evidence that it increases complications. (thieme-connect.de)
Simultaneous biliary and pancreatic drainage is rarely performed for very selected indications and its effects on postoperative pancreatic fistula are largely unknown. (thieme-connect.de)
Conclusion Preoperative biliary drainage alone has no significant influence on postoperative pancreatic fistula except when combined with pancreatic stenting. (thieme-connect.de)

Patients with postoperative fistula grades B and C showed WBC counts that did not decrease on subsequent measurements during the early postoperative period. (kjco.org)
Several pharmacological and technical interventions have been suggested to decrease the pancreatic fistula rate, but the results have been controversial. (sagepub.com)
Sealing with Hemopatch® as an adjuvant after a pancreaticoduodenectomy might offer a new possibility to decrease postoperative pancreatic fistula, with fewer severe fistulas, shorter hospital stays and reduced healthcare costs. (blogspot.com)

Modified Cattell s pancreaticojejunostomy, buttressing for soft pancreases and an isolated biliopancreatic loop are safety measurements that improve outcome after pancreaticoduodenectomy: a pilot study. (medigraphic.com)

[ 4 ] Trauma related to ERCP is thought to result from the regurgitation of amylase into the blood, which may occur in 75% of ERCPs, but most have no evidence of pancreatic injury. (medscape.com)

however, serum amylase can be normal, even in the face of massive pancreatic necrosis . (medscape.com)

By univariate and multivariate analysis using Firth logistic regression, pancreatic texture (OR = 1.205, CI = 0.103-2.476, p = 0.032) and the presence of a biliary and pancreatic stent (OR = 2.695, CI = 0.273-7.617, p = 0.027) were the significant factors affecting pancreatic fistula. (thieme-connect.de)
Factors associated with complications in patients undergoing pancreaticoduodenectomy were evaluated using multivariate logistic regression (MVA) and propensity score matching (PSM). (psu.edu)

Anatomy12

Diseases35

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment34

Phenomena and Processes3

Health Care9

POPF19

Ductal adenocarcinoma4

Anastomosis9

Adenocarcinoma5

Hemorrhage3

Duct21

Incidence4

Perioperative3

Outcomes8

Resection of pancreatic2

Cancer12

Underwent6

Clinically relevant1

Anastomotic4

Pancreas7

Complications after pancreaticoduodenectomy2

Tumors6

Surgery12

Abstract1

Postoperative Complications1

Lesions2

Gastric1

Anastomoses2

Soft pancreatic texture1

Complication3

Treatment of pancreatic1

Carcinoma2

ISGPF3

Surgical6

Consecutive pancreaticoduodenectomies1

Pancreatectomy3

Computed tomography1

Open pancreaticoduodenectomy2

Robotic pancreaticoduodenectomy1

Mortality2

Abscess1

Superior mesent1

Pancreaticogastrostomy1

Abdominal1

Malignancy1

Whipple1

Drainage3

Decrease3

Pancreaticojejunostomy1

Trauma1

Amylase1

Multivariate2