AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesHealth Care
Pancreatic FistulaPancreatectomyFistulaPancreaticoduodenectomyPancreaticojejunostomyPancreatic DiseasesCutaneous FistulaPancreatic DuctsArteriovenous FistulaGastric FistulaPancreatic NeoplasmsPancreasIntestinal FistulaBiliary FistulaSurgical StaplingDrainageBronchial FistulaVascular FistulaRectal FistulaPostoperative ComplicationsUrinary FistulaSplenectomyGastrostomyEsophageal FistulaSplenic VeinPancreatic PseudocystSuture TechniquesTreatment OutcomeRectovaginal FistulaSplenic ArteryVesicovaginal FistulaRespiratory Tract FistulaVaginal FistulaPancreatitis, ChronicTracheoesophageal FistulaJejunostomyRetrospective StudiesGastrectomyPancreatic JuiceLaparoscopyCongenital HyperinsulinismOctreotideUrinary Bladder FistulaAmylasesCyst FluidArterio-Arterial FistulaAnastomosis, SurgicalPancreatic CystEndoscopyArteriovenous Shunt, SurgicalPancreatic ExtractsTomography, X-Ray ComputedLength of StayPancreatitisNesidioblastosisAnastomosis, Roux-en-YOrgan Sparing TreatmentsCarotid-Cavernous Sinus FistulaIslets of Langerhans TransplantationAdenoma, Islet CellDuodenumReoperationCholangiopancreatography, Endoscopic RetrogradeTime FactorsNeoplasms, Cystic, Mucinous, and SerousCarcinoma, Pancreatic DuctalFollow-Up StudiesSplenic InfarctionHypoglycemiaSecretinSurgical Procedures, ElectiveIslets of LangerhansPain, Intractable
PostoperativePancreasDuctalAdvanced Pancreatic CancerPancreaticoduodenectomySurgeryCancerAdenocarcinomaResectionsMortalityCystsDuctLeakageBiliaryTumorsRisk factor for pancreaticPost-operativeAcute PancreatitisAbdominalTotal pancreatectomiesSplenectomyComplicationsAmylaseChronicSurgicalIncidental pancreaticPartial pancreatectomyPatientsPancreatitisTraumaEnzymes
Postoperative24
  • BACKGROUND: Postoperative pancreatic fistula (POPF) is a common and serious complication after distal pancreatectomy (DP). (minervamedica.it)
  • An effective and accepted score to predict the occurrence of clinically relevant (CR-) postoperative pancreatic fistula (POPF) does not exist. (minervamedica.it)
  • CONCLUSIONS: An easy-to-use postoperative score based on operation time, obesity, amylase level on drains on POD3 and pancreatic thickness on preoperative CT seems to predict the risk of developing CR-POPF. (minervamedica.it)
  • Most of these complications are related to pancreatic fistula, with serious complications of intra-abdominal abscess, postoperative bleeding, and multiorgan failure. (sagepub.com)
  • BACKGROUND: Laparoscopic distal pancreatectomy (LDP) reduces postoperative morbidity, hospital stay, and recovery as compared with open distal pancreatectomy. (elsevierpure.com)
  • Postoperative length of hospital stay and rates of pancreatic fistula, blood transfusion, and readmission were not statistically different. (elsevierpure.com)
  • Postoperative Pancreatic Fistula Following Traumatic Splenectomy: What Techniques Affect Incidence? (jtraumainj.org)
  • Impaired pancreatic perfusion in splenic vein thrombosis following laparoscopic splenectomy: A potential mechanism for postoperative pancreatic fistula after laparoscopic distal pancreatosplenectomy? (jtraumainj.org)
  • Jianhua Yu, L. Wu and B. Li, Meta-analysis of pancreaticogastrostomy versus pancreaticojejunostomy on occurrences of postoperative pancreatic fistula after pancreaticoduodenectomy, Asian Journal of Surgery (2015). (scipedia.com)
  • 1 Pancreatic fistula (PF) is the most devastating postoperative complication occurring in 2.5-25% patients, 2 and has become the main reason for increased morbidity and mortality, prolonged length of hospital stay, and increased medical costs. (scipedia.com)
  • After total pancreatectomy, quality of life of the patients is reduced both by surgical factors and by metabolic factors due to endocrine and exocrine insufficiency in the postoperative period. (turkjsurg.com)
  • In addition, conversion total pancreatectomy is performed in patients who are scheduled for partial pancreatectomy but considered to be at high risk of developing pancreatic fistula in the postoperative period, and completion total pancreatectomy is also performed after complications such as postoperative bleeding and abscess development after partial pancreatectomy ( 7 - 9 ). (turkjsurg.com)
  • Postoperative pancreatic fistula (POPF) is the most common major complication after pancreatectomy and it is a potentially serious and life-threatening complication that may lead to prolonged hospital stay and increased costs 7 . (baxter.nl)
  • The white blood cell (WBC) count useful as a predictive marker of postoperative pancreatic fistula. (kjco.org)
  • Thirty patients (8%) developed pancreatic fistula grade B and C. The WBC count, measured every other day, was significantly higher every other day during the first 7 postoperative days in patients who developed pancreatic fistula grade B and C, compared with those patients who did not develop pancreatic fistula. (kjco.org)
  • The WBC count cutoff value of 13.07×10 9 /L, 10.37×10 9 /L on postoperative day 1,7 yielded a sensitivity of 57%, 70%, specificity of 53%, 67% for the detection of pancreatic fistula. (kjco.org)
  • Patients with postoperative fistula grades B and C showed WBC counts that did not decrease on subsequent measurements during the early postoperative period. (kjco.org)
  • The measurement of WBC counts after pancreaticoduodenectomy can play a clinically important role in the early detection of pancreatic fistula development even from postoperative one day. (kjco.org)
  • One of the most important life-threatening complications is a postoperative pancreatic fistula (POPF) [ 4 , 5 ]. (kjco.org)
  • Several studies reported leukocytosis on postoperative day (POD) 4 or 5 is related with pancreatic anastomotic leakage after PD [ 13 ]. (kjco.org)
  • Postoperative acute pancreatitis (POAP) is a specific complication after pancreatectomy. (figshare.com)
  • The acute inflammatory response of the residual pancreas may affect the healing of pancreatoenteric anastomoses, leading to postoperative pancreatic fistulas (POPFs), abdominal infections, and even progressive systemic reactions, conditions that negatively affect patients' prognoses and can cause death. (figshare.com)
  • The aim of this study was the bi-national analysis of patients who underwent pancreatic resection for suspected chronic pancreatitis at an Austrian and a German high-volume center with regard to overall postoperative outcome and incidental carcinoma sequence. (iiarjournals.org)
  • Postoperative pancreatic fistula: an international study group (ISGPF) definition. (edu.pl)
Pancreas19
  • 1. Introduction Pancreaticoduodenectomy (PD) is one of the standard treatments for various benign and malignant disease of the pancreatic head and periampullary region and distal pancreatectomy for lesions in the tail of pancreas. (sagepub.com)
  • A pancreatic injury is some form of trauma sustained by the pancreas. (wikipedia.org)
  • We herein report the outcomes of four cases of LA spleen-preserving distal pancreatectomy (Warshaw technique [WT]) in living pancreas donors. (elsevierpure.com)
  • Pancreatic resection may be required in the treatment of patients with pathologies of the pancreas. (turkjsurg.com)
  • Pancreatic resection may be required in the treatment of patients with pathologies such as solid or cystic tumors of the pancreas, pancreatic trauma, chronic hereditary pancreatitis ( 2 - 4 ). (turkjsurg.com)
  • Common indications for elective total pancreatectomy include chronic pancreatitis that is refractory to medical management, premalignant lesions (intraductal papillary mucinous neoplasms) where partial resection is not sufficient, pancreatic neuroendocrine tumors, and malignant tumors of the pancreas ( 2 - 4 ). (turkjsurg.com)
  • Another reason for the high mortality and morbidity rates in pancreatic surgery is the anatomical location of the pancreas and the multiple gastrointestinal system (GIS) reconstructions after resection. (turkjsurg.com)
  • These techniques are used regularly for surgery of the pancreas including distal pancreatectomy and pancreatoduodenectomy. (biomedcentral.com)
  • We have particular interest in improving the clinical management of surgical diseases of the pancreas, including pancreatic cancer, chronic pancreatitis, and pancreatic cysts. (tum.de)
  • Pancreatectomy is a surgical procedure to remove all or part of the Pancreas . (mymeditravel.com)
  • The procedure is usually performed to treat several conditions that involve the pancreas, such as pancreatitis, benign pancreatic tumors, and pancreatic cancer. (mymeditravel.com)
  • There are two types of pancreatectomy: distal (to remove only the body and tail of the pancreas) and total (to remove the whole pancreas), both are performed under general anesthetic. (mymeditravel.com)
  • Chronic pancreatitis (CP) is a progressively evolving inflammation of the pancreas along with destruction of the pancreatic parenchyma and its replacement by fibrotic tissue that results in progressive loss of endocrine and exocrine functionality ( 1 ). (iiarjournals.org)
  • The pancreatic neck is the arbitrary junction between the head and body of the pancreas. (medscape.com)
  • Adenocarcinomas of the distal pancreas account for 15-25% of pancreatic adenocarcinomas . (medscape.com)
  • Spleen-preserving distal pancreatectomy is contraindicated for malignant lesions of the distal pancreas. (medscape.com)
  • Contraindications to distal pancreatosplenectomy and spleen-preserving pancreatectomy include metastatic disease, peritoneal carcinosis, vascular invasion, and pancreatitis involving the entire pancreas. (medscape.com)
  • This CT scan of the abdomen in the region of the pancreas demonstrates a large well-marginated cystic structure that represents a pancreatic pseudocyst. (medscape.com)
  • Hereditary pancreatitis in children, the second most common congenital pancreatic disorder following cystic fibrosis, is characterized by an alteration in the long arm of chromosome 7, which yields an aberrant trypsinogen protein that may induce autodigestion of the pancreas. (medscape.com)
Ductal7
  • The influence of neural invasion on survival and tumor recurrence in pancreatic ductal adenocarcinoma - A systematic review and meta-analysis. (tum.de)
  • The impact of neoadjuvant therapy on the histopathological features of pancreatic ductal adenocarcinoma - A systematic review and meta-analysis. (tum.de)
  • Meta-analysis of the impact of neoadjuvant therapy on patterns of recurrence in pancreatic ductal adenocarcinoma. (tum.de)
  • Resection margin status at the portomesenteric axis may not determine oncologic outcome after pancreaticoduodenectomy for lymph node-positive pancreatic ductal adenocarcinoma. (unibe.ch)
  • Predicting long-term disease-free survival after resection of pancreatic ductal adenocarcinoma: a nationwide cohort study. (dpcg.nl)
  • Design: nationwide cohort study amongst 836 patients who received surgery for pancreatic ductal adenocarcinoma between 2014-2016 in the Netherlands. (dpcg.nl)
  • Oba A, Wu YHA, Schulick R, Del Chiaro M. Author response to: Comment on: Comparing neoadjuvant chemotherapy with or without radiation therapy for pancreatic ductal adenocarcinoma: National Cancer Database cohort analysis. (cuanschutz.edu)
Advanced Pancreatic Cancer2
  • Specific areas of current research include blood transfusion practices during pancreatic cancer surgery, irreversible electroporation for locally advanced pancreatic cancer, and improving long-term quality of life after pancreatectomy. (columbia.edu)
  • Robotic Appleby modified procedure for locally advanced pancreatic cancer (with video). (canceropole-est.org)
Pancreaticoduodenectomy9
Surgery16
  • Pancreatic injuries are classified according to the criteria of the American Association for the Surgery of Trauma (AAST). (wikipedia.org)
  • Although some reports have described hand-assisted laparoscopic surgery for distal pancreatectomy in living-donor operations, less-invasive laparoscopy-assisted (LA) procedures are expected to increase the donor pool. (elsevierpure.com)
  • After the first successful total pancreatectomy was performed by the Viennese surgeon Theodor Billroth in 1884, there have been many developments in pancreatic surgery over the last century, but the high mortality and morbidity rates have made surgeons hesitant about pancreatic surgery ( 5 ). (turkjsurg.com)
  • Purpose: To evaluate the incidence, predictors and clinical outcome of pancreatic fistulas in patients receiving splenectomy during cytoreductive surgery for advanced or recurrent ovarian cancer. (unicatt.it)
  • Although the median length of hospital stay was higher in women with pancreatic leakage (p-value = 0.008), the median time from surgery to adjuvant treatment was not significantly increased. (unicatt.it)
  • Robotic pancreatic surgery is associated with slightly decreased blood loss and decreased length of stay compared to open surgery. (biomedcentral.com)
  • These succinct "three rules of surgery" represent how pancreatic surgery stands apart from other areas of General Surgery and the reverence (and fear) that generations of surgeons have had for this organ [ 1 , 2 ]. (biomedcentral.com)
  • Pancreatic surgery as we know it developed at the end of the nineteenth century. (biomedcentral.com)
  • At that time, surgery for patients with obstructive jaundice was limited by coagulopathy, and palliative biliary bypass was developed to relieve obstruction caused by pancreatic malignancies [ 2 ]. (biomedcentral.com)
  • The next landmark in pancreatic surgery was the distal pancreatic resection. (biomedcentral.com)
  • Welcome to the Website of the Pancreatic Clinical Study Unit (PanCSU) at the Department of Surgery at the Technical University of Munich. (tum.de)
  • In pancreatic surgery, the most serious complication is pancreatic leakage in the form of post-operative pancreatic fistula. (baxter.nl)
  • Pancreatic surgery is challenging and associated with high morbidity. (kjco.org)
  • The subgroup results of the meta-analysis by different POAP diagnostic criteria showed that the incidences of POAP were 15% (95% CI, 5-38) in the International Study Group for Pancreatic Surgery group, 51% (95% CI, 42-60) in the Connor group, 7% (95% CI, 2-24) in the Atlanta group, and 5% (95% CI, 2-14) in the unclear group. (figshare.com)
  • Fully closed-loop insulin delivery in patients undergoing pancreatic surgery. (unibe.ch)
  • [ 3 ] Surgery is indicated for pain, pseudocysts , suspicion of malignancy, stenosis of the mid to distal pancreatic duct, pancreatolithiasis, and stenosis of the celiac or mesenteric vessels. (medscape.com)
Cancer14
  • He focuses on the operative management of pancreatic cancer, liver cancer, gallbladder disease and metastases to the liver and abdominal peritoneum. (columbiasurgery.org)
  • Is 6 Months the Optimal Duration of Adjuvant Chemotherapy for Pancreatic Cancer? (cancerdiagnosisprognosis.org)
  • Indications and techniques of extended resection for pancreatic cancer. (medicalnote.jp)
  • In our study, we retrospectively analyzed the data of patients diagnosed with pancreatic cancer, intrapapillary mucinous neoplasia, pancreatic neuroendocrine tumors, and chronic pancreatitis undergoing from partial to total pancreatic resections in our clinic between 12/2017 and 12/2022. (turkjsurg.com)
  • For example, if you have pancreatic cancer, your doctor may suggest you undergo chemotherapy or radiation therapy to kill the cancer cells. (mymeditravel.com)
  • After pancreatectomy, most of your symptoms should be relieved and you may be cured or be put in remission (if you have pancreatic cancer). (mymeditravel.com)
  • In addition, CP is considered a risk factor for pancreatic cancer, whereas the overall incidence of cancer occurrence remains unspecified ( 7 , 8 ). (iiarjournals.org)
  • Recommendations for screening of patients with CP for pancreatic cancer do not exist and, due to a wide diversity of clinical and morphological presentations of CP, the differentiation between CP and pancreatic cancer, especially in cases when malignant tumor growth appears in the course of CP, is challenging ( 4 ). (iiarjournals.org)
  • Spatially restricted tumour-associated and host-associated immune drivers correlate with the recurrence sites of pancreatic cancer. (unibe.ch)
  • High tumor mutational burden (TMB) identifies a microsatellite stable pancreatic cancer subset with prolonged survival and strong anti-tumor immunity. (unibe.ch)
  • Hariharan D, Saied A, Kocher HM: Analysis of mortality rates for pancreatic cancer across the world. (edu.pl)
  • Siriwardana H, Siriwardena A: Systematic review of outcome of synchronous portal-superior mesenteric vein resection during pancreatectomy for cancer. (edu.pl)
  • A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. (edu.pl)
  • Management and Outcomes of Pancreatic Cancer in French Real-World Clinical Practice. (canceropole-est.org)
Adenocarcinoma3
  • The high incidence of incidental pancreatic adenocarcinoma especially underlines the necessity for an early surgical therapeutic approach for these patients. (iiarjournals.org)
  • Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma. (edu.pl)
  • Longterm survival after pancreatoduodenectomy for pancreatic adenocarcinoma: is cure possible? (edu.pl)
Resections7
  • Does Preoperative Estimated Glomerular Filtration Rate (eGFR) Predict Short-Term Surgical Outcomes in Patients Undergoing Pancreatic Resections? (arizona.edu)
  • In the early part of the twentieth century there were a number of surgeons who attempted and completed a variety of pancreatic resections but there was as yet no standardized approach to this organ. (biomedcentral.com)
  • Extensive vascular exposure during liver resections can increase the risk of bleeding and fistula formation. (baxter.nl)
  • Patients and Methods: Overall, 252 consecutive pancreatic resections for suspected chronic pancreatitis were performed at the two institutions between 2005 and 2015. (iiarjournals.org)
  • Results: Pancreatic resections were performed in 193 male (76.6%) and 59 female patients (23.4%), with a median age of 53.2 years. (iiarjournals.org)
  • A total of 175 resections of the pancreatic head (69.4%), 37 distal pancreatectomies (14.7%), 23 total pancreatectomies (9.1%) and 18 other pancreatic resections (7.1%) were performed within our study period. (iiarjournals.org)
  • Conclusion: The results of our study demonstrate that pancreatic resections for chronic pancreatitis may nowadays be considered technically feasible and safe. (iiarjournals.org)
Mortality4
  • The single most significant cause of morbidity and mortality after PD is the development of pancreatic leak and fistula. (sagepub.com)
  • Total pancreatectomy is a major surgical procedure with serious risk of mortality and morbidity, and patient selection is important for prognosis. (turkjsurg.com)
  • The development of pancreatic leakage was not associated with increased post-operative mortality or delay in the initiation of chemotherapy. (unicatt.it)
  • Perioperative mortality for pancreatectomy: a national perspective. (edu.pl)
Cysts1
Duct7
  • and pancreatic duct disruption based on the results of thin-cut computed tomography or endoscopic retrograde cholangiopancreatography (ERCP). (wikipedia.org)
  • The pancreatic organ injury scale, as minimally modified, is: When there is no pancreatic duct injury, typically hemostasis and surgical drainage are the main form of treatment. (wikipedia.org)
  • Unsuccessful stenting of the ruptured main pancreatic duct (MPD) was performed via endoscopic retrograde cholangiopancreatography (ERCP). (biomedcentral.com)
  • Five (35.7%) patients underwent perioperative total pancreatectomy because of high risk of pancreatic fistula development due to hard parenchyma and narrow pancreatic duct. (turkjsurg.com)
  • Long-term Risk of Pancreatic Malignancy in Patients With Branch Duct Intraductal Papillary Mucinous Neoplasm in a Referral Center. (tum.de)
  • Possible complications include dilatation, distortion and stricture of the pancreatic ducts, calcification of the pancreatic parenchyma, formation of pseudocysts, duodenal or common bile duct stenosis, or the formation of superior mesenteric, portal or splenic vein thrombosis which may each severely affect the patient's quality of life and overall prognosis ( 1 , 6 ). (iiarjournals.org)
  • Because the accessory duct is smaller in caliber than the duct of Wirsung, inadequate pancreatic drainage may result in chronic pain and recurrent pancreatitis. (medscape.com)
Leakage1
  • Perioperative morbidity was 23% (3 acute pancreatitis, 13 pancreatic fistulas, 4 abdominal abscesses, 2 pseudocysts, 1 biliary leakage). (unina.it)
Biliary1
  • Numerous congenital abnormalities of the pancreatic biliary system have been described. (medscape.com)
Tumors6
  • The Role of Endoscopic Ultrasound-Guided Ki67 in The Management of Non-Functioning Pancreatic Neuroendocrine Tumors. (columbiasurgery.org)
  • Sporadic nonfunctional pancreatic neuroendocrine tumors: Risk of lymph node metastases and aggressiveness according to tumor size: A multicenter international study. (unibe.ch)
  • Neuroendocrine tumors represent 2-4% of pancreatic tumors. (medscape.com)
  • These tumors represent 0.9-2.5% of solid pancreatic tumors, with 82-93% of cases diagnosed in young women. (medscape.com)
  • Serous cystadenomas are typically benign and represent 20-40% of cystic pancreatic tumors. (medscape.com)
  • Because of their similarities in appearance on diagnostic imaging, pancreatic pseudocysts and cystic tumors may be distinguished by endoscopic ultrasonography with fine-needle aspiration. (medscape.com)
Risk factor for pancreatic1
  • Conclusion: HIPEC was identified as a risk factor for pancreatic fistulas in patients who underwent splenectomy alone, while concomitant cholecystectomy was the only independent predictor of fistula in those receiving additional pancreatectomy. (unicatt.it)
Post-operative1
Acute Pancreatitis1
Abdominal2
  • Management of a pancreatic injury can be difficult because other abdominal organs, such as the liver, usually have sustained trauma as well. (wikipedia.org)
  • Pancreatic injuries are rare in cases of blunt abdominal trauma and therefore easily misdiagnosed at time of hospital admission. (biomedcentral.com)
Total pancreatectomies1
  • However, there has been an increase in the number of pancreatic surgeries and total pancreatectomies in the last 2-3 decades due to new treatment modalities, surgical techniques, surgeons' experience and knowledge, and the increase in the number of health care institutions with high technology and facilities. (turkjsurg.com)
Splenectomy1
Complications1
  • Pancreatic fistula (PF) hence has been one of the major complications discouraging surgeons from performing PD. (sagepub.com)
Amylase2
  • Based on multivariate analysis results, a 4 points score was created by assigning 1 point if operation time was >4 hours, amylase levels on drains' fluid >500 UI on POD 3, pancreatic thickness >10 mm and if the BMI was >30. (minervamedica.it)
  • Pancreatic injuries must be highly suspected in bicycle handlebar injuries, even if amylase/lipase levels or ultrasound findings seem unremarkable. (biomedcentral.com)
Chronic2
Surgical7
  • Surgical Management of Hepatobiliary and Pancreatic Disorders (Second ed.). doi:10.3109/9781841847603. (wikipedia.org)
  • We hypothesized that robot-assisted distal pancreatectomy (RADP) was superior to LDP as a result of improved surgical manipulation and visualization, potentially expanding the indications for minimally invasive pancreatectomy. (elsevierpure.com)
  • However, pancreatectomy is very invasive for the donor, and less-invasive surgical procedures are needed. (elsevierpure.com)
  • Lucia Moletta Pancreatic and Digestive Endocrine Surgical Unit, Fourth Surgical Clinic, University of Padua. (unina.it)
  • Anna Caterina Milanetto Pancreatic and Digestive Endocrine Surgical Unit, Fourth Surgical Clinic, University of Padua. (unina.it)
  • Valbona Liço Pancreatic and Digestive Endocrine Surgical Unit, Fourth Surgical Clinic, University of Padua. (unina.it)
  • Sergio Pedrazzoli Pancreatic and Digestive Endocrine Surgical Unit, Fourth Surgical Clinic, University of Padua. (unina.it)
Incidental pancreatic1
  • However, with the increasing use of imaging studies, more incidental pancreatic lesions are discovered and diagnosed. (medscape.com)
Partial pancreatectomy1
Patients7
  • one retrospective case review found that computed tomography had either failed to find injuries or had underestimated the severity of injury in more than half of 17 pancreatic injury patients. (wikipedia.org)
  • We report the cases of two patients who presented to our clinic 2 days in a row with a similar history of a bicycle accident and complete pancreatic rupture. (biomedcentral.com)
  • The endocrine and exocrine pancreatic insufficiency that develops in patients after total pancreatectomy can lead to a serious decrease in the quality of life of the patients due to pain, diarrhea, vomiting etc. (turkjsurg.com)
  • A total of 47 total pancreatectomy patients, 30 (63.8%) males and 17 (36.2%) females, were included in the study. (turkjsurg.com)
  • Forty (85.1%) patients used enzyme preparations to replace pancreatic enzymes. (turkjsurg.com)
  • In the overall population, a pancreatic fistula was detected in 32 (12.3%) patients, and pancreatic resection (p-value = 0.033) and HIPEC administration (p-value = 0.039) were associated with fistula development. (unicatt.it)
  • Failure to rescue in patients with distal pancreatectomy: a nationwide analysis of 10,632 patients. (canceropole-est.org)
Pancreatitis1
  • Occasionally, pancreatitis is complicated by the formation of a fibrous-walled cavity filled with pancreatic enzymes, termed a pseudocyst. (medscape.com)
Trauma1
  • Bicycle handlebar injuries are the most common cause of pancreatic trauma in children and adolescents. (biomedcentral.com)
Enzymes2
  • If you have total pancreatectomy, you may need to take insulin and enzyme supplements to prevent diarrhea, help food digestion, and help regulate blood sugar levels since your body no longer produces its own pancreatic enzymes and insulin. (mymeditravel.com)
  • Normally these cells release inactive enzymes into collecting ducts, which then drain into the main or accessory pancreatic ducts emptying directly into the duodenal lumen. (medscape.com)