• The underlying mechanism involves the formation of abnormal connective tissue within the palmar fascia. (wikipedia.org)
  • Another type of connective tissue, called fascia, surrounds and separates the tendons and muscles of the hand. (health-local.com)
  • Dupruytren's contracture is a disease that typically affects the connective tissue in the palm of the hand, although it can also impact the feet. (glutenfreeforgood.com)
  • Deep fascia is the dense fibrous connective tissue that interpenetrates and surrounds the muscles, bones, nerves and blood vessels of the body. (wikidoc.org)
  • Visceral Fascia suspends the organs within their cavities and wraps them in layers of connective tissue membranes . (wikidoc.org)
  • Involutional phase - In this phase the disease, spreads along the fascia and into the fingers, resulting in the development of a cord. (medscape.com)
  • Residual phase - During the residual phase, the disease continues to spread into the fingers and the cord tightens, creating a contracture. (medscape.com)
  • Dupuytren contracture is progressive contracture of the palmar fascial bands, causing flexion deformities of the fingers. (msdmanuals.com)
  • Treatment references Dupuytren contracture is progressive contracture of the palmar fascial bands, causing flexion deformities of the fingers. (msdmanuals.com)
  • The fascia separates into thin bands of tissue at the fingers. (health-local.com)
  • Being that our fingers are slightly bent when our hand is relaxed, many people put up with the contracture for a long time. (health-local.com)
  • The diagnosis is based on the presence of fibromatous nodule formations in the palmar fascia, which slowly (i.e. over several months or even years) progress to cords leading eventually to contractures of joints in fingers. (biomedcentral.com)
  • In stage B the disease spreads up the fascia and into the fingers, leading to the development of a cord. (biomedcentral.com)
  • In stage C the disease spreads up the fingers, eventually creating a tight cord such that the fingers are forced to progressively bend, and are unable to straighten, effecting an irreversible contracture. (biomedcentral.com)
  • Dark or Dirty appearing horizontal lines over palmar and lateral aspects of fingers. (online-sciences.com)
  • The fascia becomes thick and shortened, causing the fingers to contract and pull inward. (glutenfreeforgood.com)
  • Grade 1 disease presents as a thickened nodule and a band in the palmar apononeurosis. (biomedcentral.com)
  • Dupuytren contracture belongs to the group of fibromatoses that include plantar fibromatosis (Ledderhose disease), penile fibromatosis (Peyronie disease), and fibromatosis of the dorsal PIP joints (Garrod nodes or knuckle pads). (medscape.com)
  • Normally, the palmar fascia consists of collagen type I, but in Dupuytren patients, the collagen changes to collagen type III, which is significantly thicker than collagen type I. People with severe involvement often show lumps on the back of their finger joints (called "Garrod's pads", "knuckle pads", or "dorsal Dupuytren nodules"), and lumps in the arch of the feet (plantar fibromatosis or Ledderhose disease). (wikipedia.org)
  • Dupuytren disease (DD) is a fibrosing disorder that results in slowly progressive thickening and shorting of the palmar fascia and leads to debilitating digital contractures, particularly of the metacarpophalangeal (MCP) joints or the proximal interphalangeal (PIP) joints. (medscape.com)
  • Arrow denotes the cord often present in Dupuytren contracture. (medscape.com)
  • Dupuytren contracture is most commonly observed in persons of Northern European descent and affects 4-6% of Whites worldwide. (medscape.com)
  • Arrow denotes the typical cords of Dupuytren contracture. (medscape.com)
  • Since 2002 the Dupuytren Contracture Institute has helped people who struggle with an expanding and tightening lump on the palm. (dupuytrens-contracture.com)
  • Palmar erythema is reddish skin on the palm of the hand, which is also due to an increase in estradiol. (medmastery.com)
  • This control is lost as the disorder develops and the palmar fascia contracts, or tightens. (health-local.com)
  • The earliest sign of a contracture is a triangular "puckering" of the skin of the palm as it passes over the flexor tendon just before the flexor crease of the finger, at the metacarpophalangeal (MCP) joint. (wikipedia.org)
  • Metacarpophalangeal joint and proximal interphalangeal joint contractures are also present. (medscape.com)
  • Note the metacarpophalangeal joint contracture. (medscape.com)
  • The high density of collagen fibers is what gives the deep fascia its strength and integrity. (wikidoc.org)
  • If the hand cannot be placed flat on a table or, especially, when significant contracture develops at the proximal interphalangeal (PIP) joints, surgery is usually indicated. (msdmanuals.com)
  • Peyronie Disease Peyronie disease is fibrosis of the cavernous sheaths leading to contracture of the investing fascia of the corpora, resulting in a deviated and sometimes painful erection. (msdmanuals.com)
  • Incomplete excision or new disease results in recurrent contracture, especially in patients who are young at disease onset or who have a family history, Garrod pads, Peyronie disease, or plantar foot involvement. (msdmanuals.com)
  • After pregnancy and weight loss, the superficial fascia slowly reverts to its original level of tension. (wikidoc.org)
  • In addition to its subcutaneous presence, this type of fascia surrounds organs and glands , neurovascular bundles, and is found at many other locations where it fills otherwise unoccupied space. (wikidoc.org)
  • Surgical resection of the tumor with a longitudinal and zig-zag incision of the palm was performed exposing the mass surrounding the palmar digital branch of the median nerve. (bvsalud.org)
  • Without treatment, the contracture can become so severe that you cannot straighten your finger, and eventually you may not be able to use your hand effectively. (health-local.com)
  • The contracture is like extra scar tissue just under the skin. (health-local.com)
  • Fascia is an uninterrupted, three-dimensional web of tissue that extends from head to toe, from front to back, from interior to exterior. (wikidoc.org)
  • After injury, it is the fascia that creates an environment for tissue repair . (wikidoc.org)
  • Fascia is a highly adaptable tissue. (wikidoc.org)
  • Stage A generally starts as a small lump in the palm of the hand, often just under the digit on the palmar crease. (biomedcentral.com)
  • Although the exact cause is unknown, it occurs most often in middle-aged, white men and is genetic in nature, meaning it runs in families. (health-local.com)
  • [ 12 ] On physical examination, palmar skin blanching is seen with finger extension. (medscape.com)
  • Although the existing available biological information on DD may contain potentially valuable (though largely uninterpreted) information, the precise aetiology of DD remains unknown. (biomedcentral.com)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • Fascia functions as the body's first line of defense against pathogenic agents and infections . (wikidoc.org)