• sensitivity
  • FS patients display a multimodal change in pain sensitivity which is generalized rather than anatomically restricted. (prohealth.com)
  • To provide an example we apply these methods to data from the mechanical pain sensitivity test of the QST protocol. (peerj.com)
  • Adverse effects of opioids Common and short term Itch Nausea Vomiting Constipation Drowsiness dry mouth Other Opioid dependence Dizziness Decreased sex drive Loss of appetite impaired sexual function Decreased testosterone levels Depression Immunodeficiency opioid-induced abnormal pain sensitivity Irregular menstruation Increased risk of falls Slowed breathing Like loperamide and other opioids, morphine acts on the myenteric plexus in the intestinal tract, reducing gut motility, causing constipation. (wikipedia.org)
  • analgesia
  • It has also been demonstrated that electroacupuncture (EA) stimulation at LI18 ( Futu ), LI4 ( Hegu ) and PC6 ( Neiguan )-traditional acupuncture points that have been classically used for analgesia in thyroid surgery patients 9 -is effective, and that EA treatment may reduce the required dosages of remifentanil and acetaminophen, with a superior effect compared with acetaminophen administration alone in the reduction of postoperative pain. (bmj.com)
  • American College of R
  • Ten women (aged 25-64 years, median: 50 years) diagnosed with TMD associated with widespread pain, reported from at least three different anatomical sites apart from the jaw region and pain to palpation according to the American College of Rheumatology criteria 1990, were included in the study. (diva-portal.org)
  • Synchrony
  • A study entitled "Synchrony and exertion during dance independently raise pain threshold and encourage social bonding" concludes that group dancing, especially to energetic beats such as Gangnam Style , the international hit song released in 2012 by the South Korean rapper Psy. (painweek.org)
  • hyperalgesia
  • Following injury or the development of various pathological conditions, an abnormal degree of tenderness may develop as a result of a resetting of the pain threshold in favour of allodynia and hyperalgesia. (bmj.com)
  • Responses
  • Responses suggest that dance involving both exertive and synchronized movement "…demonstrated significant independent positive effects on pain threshold (a proxy for endorphin activation) and in-group bonding. (painweek.org)
  • This may be because experimental studies describe participants' responses exclusively in terms of thresholds that conflate several aspects of the response. (peerj.com)
  • After injury, the balance of central responses tips towards persistent pain as a result of substance P release and a reduction in nitrous oxide synthesis and also because the efficacy of inhibitory neurons is diminished by excitotoxicity. (bmj.com)
  • participants
  • The participants were asked to rate their pain on a scale from zero to 10. (drugs.com)
  • Of all the participants, 9 percent were classified as having low pain perception. (drugs.com)
  • Finally, 45 percent of the participants were rated as having high pain perception. (drugs.com)
  • Participants completed a questionnaire assessing their level of social connection and their experiences of pain. (painweek.org)
  • The availability of such standardized measures has resulted in a rapid increase in the number of studies into pain processing in healthy participants and patients. (peerj.com)
  • findings
  • Application of these methods led to intriguing findings, such as the presence lower pain-thresholds in healthy children compared to healthy adolescents. (peerj.com)
  • painful
  • For someone with a low threshold, it may become quite painful. (verywell.com)
  • That's why things that aren't painful to most people can cause pain in those with this condition. (verywell.com)
  • So if someone else feels pain from something you think shouldn't be painful, try to understand that their experience may be very different from yours. (verywell.com)
  • The temperature at which heat becomes painful for a recipient is called the heat pain threshold for that person at that time. (wikipedia.org)
  • Understanding both acute as well as chronic pain relies, to a large extent, on our ability to measure and quantify the response to painful and non-painful stimuli. (peerj.com)
  • stimuli
  • All receptors for pain stimuli are free nerve endings of groups of myelinated or unmyelinated neural fibers abundantly distributed in the superficial layers of the skin and in certain deeper tissues such as the periosteum, surfaces of the joints, arterial walls, and the falx and tentorium of the cranial cavity. (thefreedictionary.com)
  • musculoskeletal
  • Low physical activity levels and prolonged sedentary work time/hours have also been emphasized as a risk factor for developing musculoskeletal (MS) pain [ 10 , 11 ], more specifically of the neck and shoulder [ 12 ]. (hindawi.com)
  • intensity
  • Establishing the effects of low intensity cycling (LC), moderate intensity cycling (MC), and standing at a simulated office workstation on pain modulation, work performance, and metabolic expenditure. (hindawi.com)
  • Properly defined, the threshold is really the experience of the patient, whereas the intensity measured is an external event. (wikipedia.org)
  • mechanical
  • In accordance with previous research, we also found a decrease in mechanical pain threshold over pre-designated tender points and at control sites as well as a significantly larger mechanically induced neurogenic flare response. (prohealth.com)
  • The results show that adolescents are more sensitive to mechanical pain and contradict the idea that younger children simply use more lenient criteria to report pain. (peerj.com)
  • The mechanism of delayed onset muscle soreness is not completely understood, but the pain is ultimately thought to be a result of microtrauma - mechanical damage at a very small scale - to the muscles being exercised. (wikipedia.org)
  • dorsal
  • Acute noxious input into the dorsal horn of the spinal cord was apparently normal, but the increased input associated with inflammatory pain measured using c-Fos staining was diminished. (jneurosci.org)
  • The results indicate that patients with FS exhibit a significant reduction in heat pain threshold when tested on the dorsal surface of the hand. (prohealth.com)
  • study
  • At least one study shows that pain thresholds drop following exercise for people with this condition. (verywell.com)
  • The DRD1 gene was more common among those with low pain perception, the study revealed. (drugs.com)
  • The aim for this study was to investigate the effect of topical anesthesia on PPT for jaw muscles in patients with widespread pain. (diva-portal.org)
  • In conclusion, the study showed that application of topical anesthesia had no significant effect on PPT in patients with widespread pain. (diva-portal.org)
  • Thirty years ago a question about the size of abnormally tender myofascial regions arose in the relief of myofascial pain workshop of the 1981 Edinburgh meeting of the International Association of the Study of Pain, where David Simons examined a deltoid muscle of a delegate with shoulder pain. (bmj.com)
  • a 2011 study showed that attendees at a comedy club showed increased resistance to pain. (wikipedia.org)
  • response
  • Endorphins are naturally produced in response to pain, but their production can also be triggered by various human activities. (wikipedia.org)
  • innervation
  • pain felt in an area distant from the site of pathology but not mediated through a common innervation. (thefreedictionary.com)
  • New terminals sprout and increase synaptic contacts outside the injured region's original innervation, producing referred pain. (bmj.com)
  • researchers
  • Researchers pinpointed four genes that could help explain why perceptions of pain differ from person to person. (drugs.com)
  • After excluding those who reported their pain as zero, the researchers divided the remaining patients into three groups depending on their pain score. (drugs.com)
  • The researchers found this gene variant was 33 percent more prevalent in the low-pain group than in the high-pain group. (drugs.com)
  • neck
  • Methods The pain model was established by making a longitudinal midline neck incision in 60 rats. (bmj.com)
  • objective
  • Objective Acupuncture therapy effectively reduces post-surgical pain, but its mechanism of action remains unclear. (bmj.com)
  • studies
  • Behavioral studies showed that inflammatory pain was attenuated or abolished. (jneurosci.org)
  • Additionally, lactic acid is known from multiple studies to return to normal levels within one hour of exercise, and therefore cannot cause the pain that occurs much later. (wikipedia.org)
  • research
  • To receive news and publication updates for Pain Research and Management, enter your email address in the box below. (hindawi.com)
  • found
  • Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals. (wikipedia.org)
  • patients
  • Finding genes that maybe play a role in pain perception could provide a target for developing new therapies and help physicians better understand their patients' perceptions of pain. (drugs.com)
  • Postoperative pain control is an important concern for both patients and surgeons. (bmj.com)
  • muscles
  • Delayed onset muscle soreness (DOMS) is the pain and stiffness felt in muscles several hours to days after unaccustomed or strenuous exercise. (wikipedia.org)