• Comparison of a drug versus money and drug versus drug self-administration choice procedure with oxycodone and morphine in opioid addicts. (kaiserpermanente.org)
  • This double-blind, placebo-controlled study investigated the effects of oral morphine (0, 45, 135 mg/70 kg) and oral oxycodone (0, 15, 45 mg/70 kg) on buprenorphine-maintained opioid addicts. (kaiserpermanente.org)
  • Morphine is a potent opioid drug derived from the opium poppy plant . (opiates.com)
  • Furthermore, reports by the National Institute of Drug Addiction (NIDA) show that morphine acts by attaching to the opioid receptors located in the brain, spinal cord, and gastrointestinal tract. (opiates.com)
  • We found low-certainty evidence that there may be little to no difference in pain intensity, pain relief and adverse events between oxycodone and other strong opioids including morphine, commonly considered the gold standard strong opioid. (cochrane.org)
  • In the opioid group, the first step was immediate-release morphine, oxycodone, or hydrocodone/acetaminophen. (cdc.gov)
  • The members of the Anesthetic and Analgesic Drug Products Advisory Committee and the Drug Safety and Risk Management Advisory Committee voted 23 to 0 to support approval of Collegium Pharmaceutical's Xtampza ER (oxycodone extended-release capsules), for management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternatives are inadequate. (medscape.com)
  • Secondary endpoints were pain scores (NRS 0-10), morphine equivalents, patient satisfaction, quality of recovery and opioid-related side effects. (bvsalud.org)
  • Researchers working for a pharmaceutical company who were developing medications for pain as an alternative to morphine originally developed nitazenes from synthetic compounds about 60 years ago, but abandoned them because they had a high potential for overdose, Alan says. (wtop.com)
  • Morphine is a highly potent opiate (narcotic) analgesic because it treats moderate to moderately severe chronic pain. (opiates.com)
  • Morphine is a fast-acting opiate analgesic and the primary agent in opium. (opiates.com)
  • I've been reading up on the period of history known as The Great Binge (1870-1914) in which patent medicines were abundant, laudanum was freely sold over the counter and morphine/heroin based cough syrups and other opiate formulations were freely handed out to women and children for minor things like menstrual cramps and colic. (metafilter.com)
  • The first of the three opiate addiction epidemics involved opium and morphine. (hnn.us)
  • But the most prolific source of medical addiction was the hypodermic administration of morphine, typically initiated by a physician. (hnn.us)
  • The likelihood of morphine addiction increased if the physician or patient continued injections during the course of an extended and painful illness. (hnn.us)
  • Retraction Note: Oxycodone versus morphine for analgesia after laparoscopic endometriosis resection. (nih.gov)
  • Oxycodone versus morphine for analgesia after laparoscopic endometriosis resection. (nih.gov)
  • Our conclusions are consistent with other reviews and suggest that, while the reliability of the evidence base is low, given the absence of important differences within this analysis, it seems unlikely that larger head-to-head studies of oxycodone versus morphine are justified, although well-designed trials comparing oxycodone to other strong analgesics may well be useful. (cochrane.org)
  • Morphine is commonly given to patients before and after surgical procedures to reduce pain. (livescience.com)
  • According to data from IMS Health cited by the FDA, the number of extended-release oxycodone formulations dispensed by outpatient retail pharmacies has been declining, while single-entity IR oxycodone prescriptions (which do not have abuse-deterrent properties) have been on the rise - up 52%, from 10.4 million in 2010 to 15.8 million in 2014. (medscape.com)
  • Extended-release Morphine tablets are only used by patients who require around the clock pain relief, while the short-acting formulation is taken as needed. (opiates.com)
  • Canton, Massachusetts-based Collegium showed that the medication could be given by breaking open the capsule and pouring the oxycodone microspheres into a feeding tube or sprinkling them onto soft food or directly into the mouth. (medscape.com)
  • When attempting a morphine detox, consider detoxing under the supervision of an experienced physician. (opiates.com)
  • Prescriptions for extended-release oxycodone declined by about a third over the same period, from 7.3 million in 2010 to 4.7 million in 2014. (medscape.com)
  • Hallucinations (where people experience imaginary things, e.g. hearing voices) are much less common as a side effect of strong painkillers, and we found that they were less likely with oxycodone than with morphine. (cochrane.org)
  • In general, the studies showed no difference between oxycodone taken every 4-6 (immediate-release) or every 12 (controlled-release) hours. (cochrane.org)
  • Yesterday, members of the panel voted 23 to 1 against allowing Purdue Pharma's Avridi , the first immediate-release oxycodone tablet to come with abuse-deterrent properties. (medscape.com)
  • Understandably, euphoria and feelings of relaxation keep many people using morphine. (opiates.com)
  • SILVER SPRING, MD - A US Food and Drug Administration (FDA) advisory committee has recommended approval of a new extended-release, abuse-deterrent oxycodone that may be an advance over similar products. (medscape.com)