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  • thiobarbituric acid react
  • Hepatotoxicity was evaluated by the increased activities of serum hepatospecific enzymes namely aspartate transaminase, alanine transaminase, alkaline phosphatase, gamma glutamyl transferase, lactate dehydrogenase and total bilirubin along with increased elevation of lipid peroxidative markers, thiobarbituric acid reactive substances, lipid hydroperoxides, protein carbonyl content and conjugated dienes. (omicsonline.org)
  • induces
  • Elevated human amylin secretion promotes its deposition in the pancreas ( 1 ), which induces oxidative stress ( 2 ), activation of the NLRP3 inflammasome, and release of interleukin (IL)-1β ( 3 ), a cytokine involved in a plethora of inflammatory responses ( 4 ). (diabetesjournals.org)
  • cardiovascular
  • The hyperglycemia-induced oxidative stress in diabetes mellitus (DM) is the major factor in the pathogenesis of cardiovascular complications. (glucosehealth.com)
  • National Safety Associates, the owner of Juice Plus, claim that it is "the next best thing to eating fruits and vegetables", containing the "nutritional essence of 17 different fruits, vegetables, and grains" with key phytonutrients and that the product is absorbed by the body, reduces oxidative stress, promotes cardiovascular wellness, supports a healthy immune system, and helps protect DNA. (wikipedia.org)
  • humans
  • The efficacy of Protandim in humans has been investigated in three double-blind, randomized, placebo-controlled clinical trials, which showed it to have no significant overall effect on SOD or oxidative stress levels. (wikipedia.org)
  • important
  • I've repeatedly stated it's very important to maintain the proper ratio balance between omega-3 and omega-6, and medical researchers are also starting to realize and stress this importance. (mercola.com)
  • Short-term oxidative stress may also be important in prevention of aging by induction of a process named mitohormesis. (wikipedia.org)
  • free
  • The Free Radical Theory of Aging mechanistically links oxidative stress to aging. (hindawi.com)
  • The low plasma level of LPO in Okinawan centenarians, compared to younger controls, argues for protection against oxidative stress in the centenarian population and is consistent with the predictions of the Free Radical Theory of Aging. (hindawi.com)
  • It can be hypothesized that by the triggering of oxidative stress by TiO2 microparticles, level of free radicals was quantified on snail and the measuring of ROM's on snails hemolymph confirm the high production of ROS. (studiauniversitatis.ro)
  • In 1981 Sevanian became one of the founding faculty members of Dr. Paul Hochstein's Institute for Toxicology at the University of Southern California (USC), which specialized in free radical and oxidative stress research. (wikipedia.org)
  • example
  • For example, the melting temperature of di-oleoyl-phosphatidylethanolamine is -16 °C while the melting temperature of di-oleoyl-phosphatidylcholine is -20 °C. If the lipids had two palmitoyl chains, phosphatidylethanolamine would melt at 63°C while phosphatidylcholine would melt already at 41 °C. Lower melting temperatures correspond, in a simplistic view, to more fluid membranes. (wikipedia.org)
  • For example, in addition to the four classes of F2-isoprostanes that can arise from arachidonic acid, peroxidation of eicosapentaenoic acid (EPA) is predicted to lead to the generation of six classes of F3 isoprostanes, α-linolenic and γ-linolenic acids to two classes of E1- and F1-isoprostanes, and docosahexaenoic acid to eight classes of D4-isoprostanes and eight classes of E4-isoprostanes. (wikipedia.org)
  • tissues
  • In addition, antiquitin plays a role in protecting cells and tissues from the damaging effects of osmotic stress, presumably through the generation of osmolytes. (wikipedia.org)
  • biological
  • Use of MDA analysis and/or the TBA test and interpretation of sample MDA content and TBA test response in studies of lipid peroxidation require caution, discretion, and (especially in biological systems) correlative data from other indices of fatty peroxide formation and decomposition. (wikipedia.org)
  • Conclusion
  • These and other considerations from the extensive literature on MDA, TBA reactivity, and oxidative lipid degradation support the conclusion that MDA determination and the TBA test can offer, at best, a narrow and somewhat empirical window on the complex process of lipid peroxidation. (wikipedia.org)
  • acid
  • Tribulus does so by inhibiting the peroxidation of arachidonic acid . (ayurvedicscience.com)
  • In biology, hypochlorous acid is generated in activated neutrophils by myeloperoxidase-mediated peroxidation of chloride ions, and contributes to the destruction of bacteria. (wikipedia.org)
  • Thiobarbituric acid reactive substances - TBARS - are formed as a byproduct of lipid peroxidation (i.e. as degradation products of fats) which can be detected by the TBARS assay using thiobarbituric acid as a reagent. (wikipedia.org)
  • production
  • Here, we have characterized mitochondrial function, in particular as it regards the steps of oxidative phosphorylation and ROS production, in airway cells either homozygous for the F508del-CFTR allele or stably expressing wt-CFTR. (springer.com)
  • We find that oxygen consumption, ΔΨ generation, adenine nucleotide translocator-dependent ADP/ATP exchange and both mitochondrial Complex I and IV activities are impaired in CF cells, while both mitochondrial ROS production and membrane lipid peroxidation increase. (springer.com)
  • The production of this aldehyde is used as a biomarker to measure the level of oxidative stress in an organism. (wikipedia.org)
  • treatment
  • 1, Sayfa(lar) 055-061.The effect of diosmin-hesperidin combination treatment on the lipid profile and oxidative-antioxidative system in highcholesterol diet-fed rats.Alptekin Yasim. (melcalin.com)
  • major
  • Dolichols are the major lipid component (14% by mass) of human substantia nigra (SN) neuromelanin. (wikipedia.org)
  • profile
  • The probiotics are capable of preventing and treating diseases or disorders associated with an abnormal metabolic profile, especially a lipid profile by normalizing the profile. (patentsencyclopedia.com)
  • study
  • The present study suggested that the anti-oxidant and anti-inflammatory effect of rutin may prevent CP-induced nephrotoxicity via decreasing the oxidative stress, inhibiting the interconnected ROS/JNK/TNF/P38 MAPK signaling pathways, and repairing the histopathological changes against cisplatin administration. (biomedcentral.com)
  • One study of elderly people found that 400 mg of vitamin C per day (for a one-year period) reduced serum lipid peroxide levels significantly. (biomatrixone.com)